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DE60045681D1 - Vaskuläre adhesionsmoleküle und modulierung ihrer funktion - Google Patents

Vaskuläre adhesionsmoleküle und modulierung ihrer funktion

Info

Publication number
DE60045681D1
DE60045681D1 DE60045681T DE60045681T DE60045681D1 DE 60045681 D1 DE60045681 D1 DE 60045681D1 DE 60045681 T DE60045681 T DE 60045681T DE 60045681 T DE60045681 T DE 60045681T DE 60045681 D1 DE60045681 D1 DE 60045681D1
Authority
DE
Germany
Prior art keywords
adhesion molecules
modulation
function
vascular adhesion
cram
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60045681T
Other languages
English (en)
Inventor
Beat Albert Imhof
Michel Aurrand-Lions
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Serono SA
Original Assignee
Merck Serono SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Serono SA filed Critical Merck Serono SA
Application granted granted Critical
Publication of DE60045681D1 publication Critical patent/DE60045681D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Materials For Medical Uses (AREA)
DE60045681T 1999-03-11 2000-03-13 Vaskuläre adhesionsmoleküle und modulierung ihrer funktion Expired - Lifetime DE60045681D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99200746 1999-03-11
PCT/EP2000/002219 WO2000053749A2 (en) 1999-03-11 2000-03-13 Vascular adhesion molecules and modulation of their function

Publications (1)

Publication Number Publication Date
DE60045681D1 true DE60045681D1 (de) 2011-04-14

Family

ID=8239973

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60045681T Expired - Lifetime DE60045681D1 (de) 1999-03-11 2000-03-13 Vaskuläre adhesionsmoleküle und modulierung ihrer funktion

Country Status (22)

Country Link
US (3) US7393651B2 (de)
EP (2) EP2292761A1 (de)
JP (2) JP4836329B2 (de)
CN (2) CN100469878C (de)
AT (1) ATE500328T1 (de)
AU (1) AU782139B2 (de)
BR (1) BR0008915A (de)
CA (1) CA2362896C (de)
CZ (1) CZ303128B6 (de)
DE (1) DE60045681D1 (de)
EE (1) EE05497B1 (de)
ES (1) ES2361905T3 (de)
HU (1) HU229376B1 (de)
IL (1) IL145310A0 (de)
IS (1) IS2819B (de)
MX (1) MXPA01009110A (de)
NO (1) NO333085B1 (de)
NZ (1) NZ514091A (de)
PL (1) PL207994B1 (de)
RU (1) RU2244748C2 (de)
WO (1) WO2000053749A2 (de)
ZA (1) ZA200107283B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8088386B2 (en) 1998-03-20 2012-01-03 Genentech, Inc. Treatment of complement-associated disorders
US8007798B2 (en) 1997-11-21 2011-08-30 Genentech, Inc. Treatment of complement-associated disorders
EP2292761A1 (de) * 1999-03-11 2011-03-09 Merck Serono S.A. Vaskuläre Adhesionsmoleküle und Modulierung ihrer Funktion
GB0100750D0 (en) * 2001-01-11 2001-02-21 Inpharmatica Ltd Novel proteins
WO2003006673A2 (en) * 2001-07-11 2003-01-23 Texas Biotechnology Corporation A nucleic acid encoding a human junctional adhesion protein (jam3)
EP1533617A1 (de) * 2003-11-19 2005-05-25 RMF Dictagene S.A. Angiogenese inhibierende Moleküle, deren Auswahl, Herstellung und Benutzung zur Behandlung und Diagnose von Krebs
US7642341B2 (en) 2003-12-18 2010-01-05 Merck Serono S.A. Angiogenesis inhibiting molecules, their selection, production and their use in the treatment of cancer
MX337061B (es) 2005-11-04 2016-02-11 Genentech Inc Uso de inhibidores de la via del complemento para tratar enfermedades oculares.
RU2464030C2 (ru) * 2006-05-26 2012-10-20 Регадо Байосайенсиз, Инк. Введение противосвертывающей системы reg1
EP2068928A2 (de) 2006-09-28 2009-06-17 Merck Serono SA Junctional adhesion molecule-c (jam-c) bindende verbindungen und anwendungsverfahren davon
MY157948A (en) 2006-11-02 2016-08-30 Genentech Inc Humanized anti-factor d antibodies
FR2909092B1 (fr) * 2006-11-24 2012-10-19 Pf Medicament Nouveaux anticorps anti-proliferation
AR066660A1 (es) 2007-05-23 2009-09-02 Genentech Inc Prevencion y tratamiento de condiciones del ojo asociadas con su complemento
JP5815945B2 (ja) * 2007-08-06 2015-11-17 ノクソン・ファルマ・アクチエンゲゼルシャフト Ｓｄｆ−１結合核酸およびその使用
CR20170001A (es) 2008-04-28 2017-08-10 Genentech Inc Anticuerpos anti factor d humanizados
CR20160132A (es) 2013-08-12 2016-08-25 Genentech Inc Composiciones y método para tratar condiciones asociadas con el complemento
MX2016014160A (es) 2014-05-01 2017-02-16 Genentech Inc Variantes del anticuerpo anti-factor d y sus usos.
WO2017075173A2 (en) 2015-10-30 2017-05-04 Genentech, Inc. Anti-factor d antibodies and conjugates
CN108472382A (zh) 2015-10-30 2018-08-31 豪夫迈·罗氏有限公司 抗-因子d抗体变体缀合物及其用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000053753A2 (en) * 1999-03-08 2000-09-14 Genentech, Inc. Promotion or inhibition of angiogenesis and cardiovascularization
US20030170864A1 (en) * 2000-05-30 2003-09-11 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
SE9604470D0 (sv) * 1996-12-04 1996-12-04 Tamas Bartfai Konsulting Ab Transmembrane component of tight junction
JP2001524814A (ja) * 1997-03-14 2001-12-04 ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド ２８種類のヒト分泌タンパク質
JP2002503955A (ja) * 1997-03-21 2002-02-05 ジェネティックス・インスチチュート・インコーポレーテッド 分泌蛋白およびそれらをコードするポリヌクレオチド
ATE361933T1 (de) 1997-08-01 2007-06-15 Serono Genetics Inst Sa 5' ests für sekretierte proteine aus gehirngeweben
US20030044839A1 (en) 1997-09-17 2003-03-06 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP1002864A1 (de) 1998-11-10 2000-05-24 Universita' degli studi di Bologna HIgR und relatierte V Domäne zur Herstellung eines Arzneimittels zur Vorbeugung oder Behandlung von HSV-1, HSV-2 und BHV Infektionen
EP1141285A2 (de) * 1998-12-16 2001-10-10 Genentech, Inc. Ausgeschiedene und transmembran-polypeptide und dafür kodierende nukleinsäure
EP2292761A1 (de) * 1999-03-11 2011-03-09 Merck Serono S.A. Vaskuläre Adhesionsmoleküle und Modulierung ihrer Funktion
US7642341B2 (en) 2003-12-18 2010-01-05 Merck Serono S.A. Angiogenesis inhibiting molecules, their selection, production and their use in the treatment of cancer
EP1533617A1 (de) 2003-11-19 2005-05-25 RMF Dictagene S.A. Angiogenese inhibierende Moleküle, deren Auswahl, Herstellung und Benutzung zur Behandlung und Diagnose von Krebs

Also Published As

Publication number Publication date
CZ303128B6 (cs) 2012-04-18
CN1355843A (zh) 2002-06-26
JP2002537837A (ja) 2002-11-12
PL207994B1 (pl) 2011-02-28
US7393651B2 (en) 2008-07-01
US7670826B2 (en) 2010-03-02
US20050266426A1 (en) 2005-12-01
CN1637019A (zh) 2005-07-13
HU229376B1 (en) 2013-11-28
NZ514091A (en) 2004-01-30
HUP0200606A3 (en) 2004-11-29
JP2010233572A (ja) 2010-10-21
AU782139B2 (en) 2005-07-07
EP2292761A1 (de) 2011-03-09
JP4836329B2 (ja) 2011-12-14
RU2244748C2 (ru) 2005-01-20
NO333085B1 (no) 2013-02-25
BR0008915A (pt) 2002-04-09
WO2000053749A3 (en) 2000-12-14
US20080274970A1 (en) 2008-11-06
ZA200107283B (en) 2002-12-24
CN100469878C (zh) 2009-03-18
NO20014417L (no) 2001-11-12
EE200100472A (et) 2002-12-16
US20100267649A1 (en) 2010-10-21
IS2819B (is) 2012-12-15
EP1163337A2 (de) 2001-12-19
IL145310A0 (en) 2003-01-12
HUP0200606A2 (en) 2002-06-29
CA2362896A1 (en) 2000-09-14
ATE500328T1 (de) 2011-03-15
MXPA01009110A (es) 2002-08-20
WO2000053749A2 (en) 2000-09-14
HK1044169A1 (en) 2002-10-11
CA2362896C (en) 2012-07-31
ES2361905T3 (es) 2011-06-24
EE05497B1 (et) 2011-12-15
EP1163337B1 (de) 2011-03-02
US8143056B2 (en) 2012-03-27
IS6072A (is) 2001-09-10
PL350417A1 (en) 2002-12-16
AU4105100A (en) 2000-09-28
NO20014417D0 (no) 2001-09-11
CZ20013267A3 (cs) 2002-02-13

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