DE60045637D1 - Nicotin-acetylcholin rezeptoruntereinheit, deren isolierung und verwendung - Google Patents
Nicotin-acetylcholin rezeptoruntereinheit, deren isolierung und verwendungInfo
- Publication number
- DE60045637D1 DE60045637D1 DE60045637T DE60045637T DE60045637D1 DE 60045637 D1 DE60045637 D1 DE 60045637D1 DE 60045637 T DE60045637 T DE 60045637T DE 60045637 T DE60045637 T DE 60045637T DE 60045637 D1 DE60045637 D1 DE 60045637D1
- Authority
- DE
- Germany
- Prior art keywords
- polypeptides
- nicotin
- insulation
- unit
- acetylcholine receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108010001267 Protein Subunits Proteins 0.000 title 1
- 238000009413 insulation Methods 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 102000019315 Nicotinic acetylcholine receptors Human genes 0.000 abstract 1
- 108050006807 Nicotinic acetylcholine receptors Proteins 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000010188 recombinant method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99402371A EP1090991A1 (de) | 1999-09-29 | 1999-09-29 | Nikotin-acetylcholin-Rezeptor, dessen Isolierung und Verwendung |
| PCT/EP2000/007918 WO2001023551A1 (en) | 1999-09-29 | 2000-08-08 | Novel nicotinic acetylcholine receptor subunit, its isolation and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60045637D1 true DE60045637D1 (de) | 2011-03-31 |
Family
ID=8242126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60045637T Expired - Lifetime DE60045637D1 (de) | 1999-09-29 | 2000-08-08 | Nicotin-acetylcholin rezeptoruntereinheit, deren isolierung und verwendung |
Country Status (8)
| Country | Link |
|---|---|
| EP (2) | EP1090991A1 (de) |
| AT (1) | ATE498686T1 (de) |
| AU (1) | AU6442000A (de) |
| DE (1) | DE60045637D1 (de) |
| DK (1) | DK1222265T3 (de) |
| ES (1) | ES2358317T3 (de) |
| PT (1) | PT1222265E (de) |
| WO (1) | WO2001023551A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1190708A1 (de) * | 2000-09-21 | 2002-03-27 | Tinnitus Forschungs- und Entwicklungs GmbH | Medizinische Verwendung von Verbindungen |
| EP1190709A1 (de) * | 2000-09-21 | 2002-03-27 | Tinnitus Forschungs- und Entwicklungs GmbH | Behandlung von Tinnitus |
| EP2051726B1 (de) * | 2006-07-18 | 2018-04-18 | University of Utah Research Foundation | Verfahren zur behandlung von schmerzen und screening von analgetischen verbindungen |
| US9284358B2 (en) | 2006-07-18 | 2016-03-15 | University Of Utah Research Foundation | Conotoxin peptides |
| US12227771B2 (en) * | 2019-05-17 | 2025-02-18 | Janssen Pharmaceutica Nv | Expression systems and methods of use thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5683912A (en) * | 1994-07-21 | 1997-11-04 | The Salk Institute For Biological Studies | Cloning and expression of a novel acetylcholine-gated ion channel receptor subunit |
| US5599709A (en) * | 1989-09-28 | 1997-02-04 | The Salk Institute For Biological Studies | Recombinant DNA encoding neuronal α-bungarotoxin-binding proteins |
| US6485967B1 (en) * | 1995-06-07 | 2002-11-26 | Merck & Co., Inc. | Human neuronal nicotinic acetylcholine receptor α6 and β3 nucleic acid |
-
1999
- 1999-09-29 EP EP99402371A patent/EP1090991A1/de not_active Withdrawn
-
2000
- 2000-08-08 AT AT00951509T patent/ATE498686T1/de active
- 2000-08-08 DK DK00951509.9T patent/DK1222265T3/da active
- 2000-08-08 EP EP00951509A patent/EP1222265B1/de not_active Expired - Lifetime
- 2000-08-08 DE DE60045637T patent/DE60045637D1/de not_active Expired - Lifetime
- 2000-08-08 PT PT00951509T patent/PT1222265E/pt unknown
- 2000-08-08 ES ES00951509T patent/ES2358317T3/es not_active Expired - Lifetime
- 2000-08-08 WO PCT/EP2000/007918 patent/WO2001023551A1/en not_active Ceased
- 2000-08-08 AU AU64420/00A patent/AU6442000A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1222265A1 (de) | 2002-07-17 |
| PT1222265E (pt) | 2011-03-22 |
| WO2001023551A1 (en) | 2001-04-05 |
| ATE498686T1 (de) | 2011-03-15 |
| DK1222265T3 (da) | 2011-06-06 |
| AU6442000A (en) | 2001-04-30 |
| EP1222265B1 (de) | 2011-02-16 |
| ES2358317T3 (es) | 2011-05-09 |
| EP1090991A1 (de) | 2001-04-11 |
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