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DE60043156D1 - Verfahren und system zur entfernung von zytokininhibitoren in patienten - Google Patents

Verfahren und system zur entfernung von zytokininhibitoren in patienten

Info

Publication number
DE60043156D1
DE60043156D1 DE60043156T DE60043156T DE60043156D1 DE 60043156 D1 DE60043156 D1 DE 60043156D1 DE 60043156 T DE60043156 T DE 60043156T DE 60043156 T DE60043156 T DE 60043156T DE 60043156 D1 DE60043156 D1 DE 60043156D1
Authority
DE
Germany
Prior art keywords
hibitors
cytokinin
patients
binds
molecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60043156T
Other languages
English (en)
Inventor
Rigdon M Lentz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biopheresis Technologies Inc
Original Assignee
Biopheresis Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biopheresis Technologies Inc filed Critical Biopheresis Technologies Inc
Application granted granted Critical
Publication of DE60043156D1 publication Critical patent/DE60043156D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • AIDS & HIV (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
DE60043156T 1999-11-10 2000-11-10 Verfahren und system zur entfernung von zytokininhibitoren in patienten Expired - Lifetime DE60043156D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16469599P 1999-11-10 1999-11-10
PCT/US2000/042090 WO2001037873A2 (en) 1999-11-10 2000-11-10 Method and system to remove cytokine inhibitor in patients

Publications (1)

Publication Number Publication Date
DE60043156D1 true DE60043156D1 (de) 2009-11-26

Family

ID=22595665

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60043156T Expired - Lifetime DE60043156D1 (de) 1999-11-10 2000-11-10 Verfahren und system zur entfernung von zytokininhibitoren in patienten

Country Status (10)

Country Link
EP (2) EP2087907B1 (de)
JP (2) JP3852755B2 (de)
AT (1) ATE445414T1 (de)
AU (1) AU783238B2 (de)
CA (1) CA2390095C (de)
DE (1) DE60043156D1 (de)
DK (2) DK2087907T3 (de)
ES (2) ES2528307T3 (de)
PT (1) PT2087907E (de)
WO (1) WO2001037873A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004014983A1 (de) 2004-03-26 2005-10-20 Univ Stuttgart Rekombinante Polypeptide der Mitglieder der TNF Ligandenfamilie und deren Verwendung
PL1949915T3 (pl) * 2004-04-30 2013-04-30 Biopheresis Tech Inc Sposób i układ do usuwania rozpuszczalnych TNFR1, TNFR2 i IL2R u pacjentów
UY30915A1 (es) * 2007-02-16 2008-09-02 Smithkline Beecham Corp Método de tratamiento de canceres
WO2012163544A1 (en) 2011-06-01 2012-12-06 Biopheresis Technologies, Inc. Removal of soluble tumor necrosis factor receptor 2 (stnfr2)
WO2013179143A2 (en) 2012-06-01 2013-12-05 Biopheresis Technologies, Inc. Sensitization of cancer cells by the removal of soluble tumor necrosis factor receptors
CN106999550B (zh) 2014-10-03 2023-02-28 纳米提克斯有限责任公司 用于抑制可溶生物分子的生物活性的组合物以及方法
CN104353061B (zh) * 2014-11-17 2017-05-17 沈阳三生制药有限责任公司 血小板生成素在辐射造成肠组织损伤中的应用
EA201890391A1 (ru) 2015-07-29 2018-08-31 НАНОТИКС, ЭлЭлСи Модульные композиции для утилизации растворимых биомолекул и связанные с этим способы
EP3374399A1 (de) 2015-11-11 2018-09-19 Opi Vi- IP Holdco LLC Zusammensetzung und verfahren für anti-tnfr2-antikörper
JP2020504177A (ja) 2017-01-04 2020-02-06 ナノティックス，エルエルシー 捕捉粒子をアセンブルするための方法
US20190083531A1 (en) 2017-09-13 2019-03-21 Bavarian Immunology Association GmbH Purified blood for use in cancer therapy

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708713A (en) * 1984-11-16 1987-11-24 Anisa Medical, Inc. Method and system for removing immunosuppressive components from the blood of mammals
US5135919A (en) 1988-01-19 1992-08-04 Children's Medical Center Corporation Method and a pharmaceutical composition for the inhibition of angiogenesis
JPH07106219B2 (ja) * 1988-08-02 1995-11-15 宇部興産株式会社 インターロイキン２レセプターの除去装置およびそれを備えた血液体外循環装置
DE68927904T2 (de) 1988-09-01 1997-09-04 Takeda Chemical Industries Ltd Fumagillol-Derivate
US5147638A (en) 1988-12-30 1992-09-15 Oklahoma Medical Research Foundation Inhibition of tumor growth by blockade of the protein C system
US5290807A (en) 1989-08-10 1994-03-01 Children's Medical Center Corporation Method for regressing angiogenesis using o-substituted fumagillol derivatives
EP0673389A1 (de) * 1992-11-19 1995-09-27 Dana Farber Cancer Institute Antikörper gegen den gm-csf rezeptor und dessen verwendung
US5629327A (en) 1993-03-01 1997-05-13 Childrens Hospital Medical Center Corp. Methods and compositions for inhibition of angiogenesis
US5994341A (en) 1993-07-19 1999-11-30 Angiogenesis Technologies, Inc. Anti-angiogenic Compositions and methods for the treatment of arthritis
AU8114494A (en) 1993-11-12 1995-05-29 Idv Operations Ireland Limited Pourer for pouring at least two different liquids
US5639725A (en) 1994-04-26 1997-06-17 Children's Hospital Medical Center Corp. Angiostatin protein
JP4170421B2 (ja) * 1996-08-06 2008-10-22 佳子 安田 増殖性臓器疾患治療・改善剤
US6620382B1 (en) * 1998-05-22 2003-09-16 Biopheresis Technologies, Llc. Method and compositions for treatment of cancers

Also Published As

Publication number Publication date
DK2087907T3 (en) 2015-01-12
JP2006249112A (ja) 2006-09-21
PT2087907E (pt) 2015-01-05
WO2001037873A3 (en) 2002-03-07
AU4505601A (en) 2001-06-04
EP2087907B1 (de) 2014-09-24
DK1227843T3 (da) 2010-02-15
JP2003514622A (ja) 2003-04-22
CA2390095C (en) 2013-01-08
AU783238B2 (en) 2005-10-06
ES2356369T3 (es) 2011-04-07
JP3852755B2 (ja) 2006-12-06
EP1227843A2 (de) 2002-08-07
ATE445414T1 (de) 2009-10-15
ES2528307T3 (es) 2015-02-06
EP2087907A3 (de) 2009-08-19
CA2390095A1 (en) 2001-05-31
EP2087907A2 (de) 2009-08-12
WO2001037873A2 (en) 2001-05-31
EP1227843B1 (de) 2009-10-14

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