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DE60041761D1 - Tribonektine - Google Patents

Tribonektine

Info

Publication number
DE60041761D1
DE60041761D1 DE60041761T DE60041761T DE60041761D1 DE 60041761 D1 DE60041761 D1 DE 60041761D1 DE 60041761 T DE60041761 T DE 60041761T DE 60041761 T DE60041761 T DE 60041761T DE 60041761 D1 DE60041761 D1 DE 60041761D1
Authority
DE
Germany
Prior art keywords
tribonektine
tribosupplementation
tribonectin
tribonectins
injured
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60041761T
Other languages
English (en)
Inventor
Gregory D Jay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhode Island Hospital
Original Assignee
Rhode Island Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23152784&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60041761(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhode Island Hospital filed Critical Rhode Island Hospital
Application granted granted Critical
Publication of DE60041761D1 publication Critical patent/DE60041761D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Conductive Materials (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Control Of Motors That Do Not Use Commutators (AREA)
DE60041761T 1999-04-23 2000-04-24 Tribonektine Expired - Lifetime DE60041761D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/298,970 US6743774B1 (en) 1999-04-23 1999-04-23 Tribonectins
PCT/US2000/010953 WO2000064930A2 (en) 1999-04-23 2000-04-24 Tribonectins

Publications (1)

Publication Number Publication Date
DE60041761D1 true DE60041761D1 (de) 2009-04-23

Family

ID=23152784

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60041761T Expired - Lifetime DE60041761D1 (de) 1999-04-23 2000-04-24 Tribonektine

Country Status (9)

Country Link
US (6) US6743774B1 (de)
EP (1) EP1173567B2 (de)
JP (5) JP2003500022A (de)
AT (1) ATE425253T1 (de)
AU (1) AU781564B2 (de)
CA (1) CA2367750C (de)
DE (1) DE60041761D1 (de)
ES (1) ES2324199T5 (de)
WO (1) WO2000064930A2 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743774B1 (en) * 1999-04-23 2004-06-01 Rhode Island Hospital Tribonectins
GB0003092D0 (en) 2000-02-10 2000-03-29 Glaxo Group Ltd Superficial zone protein-binding molecules and uses thereof
WO2001058958A1 (en) * 2000-02-09 2001-08-16 Glaxo Group Limited Antibody binding superficial zone protein and their uses in diagnosis and screening methods
EP1347993A2 (de) * 2000-12-29 2003-10-01 Glaxo Group Limited Das "superficial zone protein" und verfahren zu dessen herstellung und anwendung
JP2004534075A (ja) * 2001-06-14 2004-11-11 ノボ　ノルディスク　アクティーゼルスカブ Ｔｆｆダイマーペプチドによる粘膜修復
US20060240037A1 (en) * 2003-06-04 2006-10-26 Edward Fey Methods and compositions for the treatment and prevention of degenerative joint disorders
KR101078202B1 (ko) * 2003-08-14 2011-11-01 와이어쓰 엘엘씨 재조합 루브리신 분자 및 이의 용도
US20090155200A1 (en) * 2004-04-20 2009-06-18 Jay Gregory D Methods of promoting cartilage healing or cartilage integration
CA2575086A1 (en) * 2004-07-23 2006-02-02 Mucosal Therapeutics Llc Compositions and methods for viscosupplementation
US20080139458A1 (en) * 2004-12-03 2008-06-12 Jay Gregory D Methods of Treatment For Injured or Diseased Joints
US20070111327A1 (en) * 2005-05-05 2007-05-17 Jay Gregory D Methods of detecting lubricin
CA2652549A1 (en) * 2006-05-17 2007-12-13 Stryker Corporation Use of a soluble morphogenic protein complex for treating cartilage defects
US20090068247A1 (en) * 2007-09-12 2009-03-12 Mucosal Therapeutics Biocompatible devices coated with a tribonectin and methods for their production
US20090104148A1 (en) * 2007-09-18 2009-04-23 Jay Gregory D Treatment and prevention of joint disease
HRP20150097T1 (hr) * 2008-05-07 2015-03-27 The Regents Of The University Of California Terapijska nadopuna i poboljšanje vlaženja površine oka
CN102438645A (zh) 2009-01-13 2012-05-02 卢布里斯有限责任公司 阴道上皮界面润滑的治疗调节
WO2010087521A1 (ja) * 2009-01-29 2010-08-05 独立行政法人理化学研究所 関節疾患治療用の組み合わせ製剤
US9730865B2 (en) 2009-05-22 2017-08-15 Lubris, Llc Application and uses of PRG4 and therapeutic modulation thereof
US11213566B2 (en) 2010-01-19 2022-01-04 Lubris Llc Oral care compositions and methods
US8716204B2 (en) 2010-07-27 2014-05-06 Zimmer, Inc. Synthetic synovial fluid compositions and methods for making the same
US20130116186A1 (en) * 2011-10-04 2013-05-09 Rhode Island Hospital, A Lifespan Partner Lubricin injections to maintain cartilage health
WO2014115022A1 (en) 2013-01-25 2014-07-31 Baylor College Of Medicine A helper-dependent adenoviral gene therapy delivery and expression system
WO2015060935A1 (en) 2013-10-22 2015-04-30 Lubris, Llc Control of rheological properties of mixed hyaluronate/lubricin solutions
WO2015081121A1 (en) 2013-11-26 2015-06-04 Lubris Llc Compositions and methods for inhibiting intercellular interactions
ES3014621T3 (en) 2015-01-26 2025-04-23 Lubris Llc Use of prg4 as an anti-inflammatory agent
DK3300482T3 (da) 2015-05-19 2021-10-18 Lubris Llc Brug af prg4 til at forbedre dynamisk synsstyrke og højere ordens aberrationer
EP3769788A1 (de) 2016-01-13 2021-01-27 Genzyme Corporation Rekombinante aav-vektoren zur expression von knochenschützenden genen mit has2 und lubricin zur behandlung von osteoarthritis und verwandten gelenkerkrankungen bei säugetieren
US11137407B2 (en) 2016-02-23 2021-10-05 Lynxon Ab Method of diagnosing arthritis or other joint degrading disease
AR121396A1 (es) 2020-02-24 2022-06-01 Novartis Ag Purificación de polipéptidos producidos recombinantemente
JP7063369B2 (ja) * 2020-12-07 2022-05-09 株式会社三洋物産 遊技機
US20250282981A1 (en) 2022-04-27 2025-09-11 Lubris Llc Methods of making polymer films

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2734862A (en) 1956-02-14 Synthetic casein fiber elastic grease
US2487377A (en) 1948-04-17 1949-11-08 Socony Vacuum Oil Co Inc Lubricant
US2878184A (en) 1953-12-29 1959-03-17 Rockwell Mfg Co Hydrocarbon resistant glycerol base lubricant
AR207237A1 (es) 1974-02-25 1976-09-22 Thomas A Procedimiento para obtener extractos biologicos estables liofilizados solubles constituidos por complejos proteicos termorresistentes
EP0050644B1 (de) 1980-04-25 1985-09-18 A/S Orthana Kemisk Fabrik Sterilisierte, konservierte, stabile, mucin enthaltende lösungen und sterilisationsverfahren
IL68218A (en) * 1983-03-23 1985-12-31 Univ Ramot Compositions for cartilage repair comprising embryonal chondrocytes
US5403592A (en) * 1987-08-25 1995-04-04 Macnaught Pty Limited Lubricant composition for rheumatism
GB8803697D0 (en) 1988-02-17 1988-03-16 Deltanine Research Ltd Clinical developments using amniotic membrane cells
US5510418A (en) 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
US5260417A (en) 1989-04-03 1993-11-09 Genetics Institute, Inc. Megakaryocyte growth promoting activity protein
US5326558A (en) 1989-08-08 1994-07-05 Genetics Institute, Inc. Megakaryocytopoietic factor
US6433142B1 (en) * 1989-08-08 2002-08-13 Genetics Institute, Llc Megakaryocyte stimulating factors
AU652022B2 (en) 1991-02-12 1994-08-11 C.R. Bard Inc. Injectable medical device
JPH04278061A (ja) 1991-03-05 1992-10-02 Suntory Ltd 栄養食品
US5605938A (en) * 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate
US5515590A (en) 1994-07-19 1996-05-14 University Of Kentucky Research Foundation Method for reducing the generation of wear particulates from an implant
US5709020A (en) 1994-07-19 1998-01-20 University Of Kentucky Research Foundation Method for reducing the generation of wear particulates from an implant
US5510122A (en) 1994-09-28 1996-04-23 The Research Foundation Of State University Of New York Preparation and use of whole saliva
FR2726188B1 (fr) * 1994-11-02 1996-12-20 Inst Vaisseaux Et Du Sang Composition glycosaminoglycane/facteur de croissance megacaryocytaire, utilisation en therapeutique
US5639734A (en) * 1994-12-20 1997-06-17 Esko; Jeffrey D. Disaccharide inflammation inhibitors and uses thereof
US6096728A (en) * 1996-02-09 2000-08-01 Amgen Inc. Composition and method for treating inflammatory diseases
AT405477B (de) 1996-04-03 1999-08-25 Norbert Mag Fuchs Kombinationspräparat
WO1998018491A1 (en) 1996-10-28 1998-05-07 BURGSTINER, Jacqueline, Cook Methods and compositions for dietary supplementation
US6960562B2 (en) 1999-04-23 2005-11-01 Rhode Island Hospital, A Lifespan Partner Tribonectin polypeptides and uses thereof
US6743774B1 (en) 1999-04-23 2004-06-01 Rhode Island Hospital Tribonectins
US7001881B1 (en) 1999-04-23 2006-02-21 Rhode Island Hospital Tribonectins
JP2004517030A (ja) 1999-05-24 2004-06-10 アバロン バイオサイエンシーズ， インコーポレイテッド グリコシルトランスフェラーゼインヒビター
AU6366100A (en) * 1999-07-23 2001-02-13 Case Western Reserve University Novel methods and reagents for the treatment of osteoarthritis
US6291533B1 (en) 1999-12-22 2001-09-18 Vitamerica, Inc. Dietary supplements for each specific blood type
GB0003092D0 (en) 2000-02-10 2000-03-29 Glaxo Group Ltd Superficial zone protein-binding molecules and uses thereof
EP1347993A2 (de) 2000-12-29 2003-10-01 Glaxo Group Limited Das "superficial zone protein" und verfahren zu dessen herstellung und anwendung
AR034635A1 (es) 2001-06-25 2004-03-03 Inspire Pharmaceuticals Inc Lubricacion de las articulaciones con agonistas del receptor purinergico p2y
GB2381750A (en) 2001-10-10 2003-05-14 Inspire Pharmaceuticals Inc Treatment for enhancing joint lubrication
US20030224386A1 (en) 2001-12-19 2003-12-04 Millennium Pharmaceuticals, Inc. Compositions, kits, and methods for identification, assessment, prevention, and therapy of rheumatoid arthritis
KR101078202B1 (ko) 2003-08-14 2011-11-01 와이어쓰 엘엘씨 재조합 루브리신 분자 및 이의 용도
CA2558497A1 (en) 2004-03-05 2005-09-15 Synthes (U.S.A.) Use of a mixture for the production of an agent for treating defective or degenerated cartilage in the production of natural cartilage replacement in vitro
CA2575086A1 (en) 2004-07-23 2006-02-02 Mucosal Therapeutics Llc Compositions and methods for viscosupplementation
US20070111327A1 (en) 2005-05-05 2007-05-17 Jay Gregory D Methods of detecting lubricin

Also Published As

Publication number Publication date
ATE425253T1 (de) 2009-03-15
US8026346B2 (en) 2011-09-27
JP5909592B2 (ja) 2016-04-26
US20140179611A1 (en) 2014-06-26
AU4485200A (en) 2000-11-10
EP1173567A2 (de) 2002-01-23
AU781564B2 (en) 2005-06-02
WO2000064930A3 (en) 2001-01-25
EP1173567B1 (de) 2009-03-11
US20100204087A1 (en) 2010-08-12
JP2016041769A (ja) 2016-03-31
EP1173567B2 (de) 2012-10-31
US7618941B2 (en) 2009-11-17
JP2012070738A (ja) 2012-04-12
ES2324199T3 (es) 2009-08-03
CA2367750A1 (en) 2000-11-02
US8680057B2 (en) 2014-03-25
US6743774B1 (en) 2004-06-01
CA2367750C (en) 2013-10-22
US20130072435A1 (en) 2013-03-21
JP2016172760A (ja) 2016-09-29
WO2000064930A2 (en) 2000-11-02
JP2003500022A (ja) 2003-01-07
JP2014144015A (ja) 2014-08-14
US20040229804A1 (en) 2004-11-18
US20100048458A1 (en) 2010-02-25
ES2324199T5 (es) 2013-03-20

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