DE60041534D1 - Verfahren zur vorhersage der wahrscheinlichkeit von knochenbrüchen mittels osteocalcin-messungen - Google Patents
Verfahren zur vorhersage der wahrscheinlichkeit von knochenbrüchen mittels osteocalcin-messungenInfo
- Publication number
- DE60041534D1 DE60041534D1 DE60041534T DE60041534T DE60041534D1 DE 60041534 D1 DE60041534 D1 DE 60041534D1 DE 60041534 T DE60041534 T DE 60041534T DE 60041534 T DE60041534 T DE 60041534T DE 60041534 D1 DE60041534 D1 DE 60041534D1
- Authority
- DE
- Germany
- Prior art keywords
- coc
- toc
- mean
- person
- ioc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000000988 bone and bone Anatomy 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 238000005259 measurement Methods 0.000 title abstract 2
- 102000004067 Osteocalcin Human genes 0.000 abstract 4
- 108090000573 Osteocalcin Proteins 0.000 abstract 4
- 208000010392 Bone Fractures Diseases 0.000 abstract 3
- 208000001132 Osteoporosis Diseases 0.000 abstract 3
- 210000001124 body fluid Anatomy 0.000 abstract 3
- 239000010839 body fluid Substances 0.000 abstract 3
- 206010017076 Fracture Diseases 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/10—Musculoskeletal or connective tissue disorders
- G01N2800/108—Osteoporosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI990693A FI990693A0 (fi) | 1999-03-29 | 1999-03-29 | Menetelmä luunmurtumien ennustamiseksi osteokalsiinimääritysten avulla |
| PCT/FI2000/000227 WO2000058732A1 (en) | 1999-03-29 | 2000-03-20 | Method for prediction of bone fractures by osteocalcin measurements |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60041534D1 true DE60041534D1 (de) | 2009-03-26 |
Family
ID=8554306
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60041534T Expired - Lifetime DE60041534D1 (de) | 1999-03-29 | 2000-03-20 | Verfahren zur vorhersage der wahrscheinlichkeit von knochenbrüchen mittels osteocalcin-messungen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6967081B1 (de) |
| EP (1) | EP1166122B1 (de) |
| AT (1) | ATE422672T1 (de) |
| DE (1) | DE60041534D1 (de) |
| ES (1) | ES2320848T3 (de) |
| FI (1) | FI990693A0 (de) |
| WO (1) | WO2000058732A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040259167A1 (en) * | 1997-08-15 | 2004-12-23 | Jukka Hellman | Isolated osteocalcin fragments |
| CA2378711A1 (en) | 1999-08-14 | 2001-02-22 | November Aktiengesellschaft Gesellschaft Fur Molekulare Medizin | Method for indirectly determining the blood-clotting status |
| GB0107393D0 (en) * | 2001-03-23 | 2001-05-16 | Osteometer Biotech As | A method of assaying osteocalcin fragments in body fluids a test kit and means for carrying out the method and use of the method to monitor bone resorption |
| WO2008088401A2 (en) * | 2006-09-13 | 2008-07-24 | The Trustees Of Columbia University In The City Of New York | Methods for identifying, or assaying for agents that increase beta-cell proliferation, insulin secretion, insulin sensitivity, glucose tolerance and decreases fat mass |
| EP2326664A2 (de) * | 2008-08-27 | 2011-06-01 | Universidade Do Algarve | Ein gammacarboxyglutamatreiches protein, verfahren und assays zu seinem nachweis, seiner aufreinigung und seiner quantifizierung und anwendungen davon |
| CN120699147B (zh) * | 2025-07-04 | 2025-12-05 | 东方海洋(北京)医学研究院有限公司 | 完全羧基化骨钙素特异性单克隆抗体及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0739439B2 (ja) * | 1989-03-16 | 1995-05-01 | 寳酒造株式会社 | モノクローナル抗体及びその使用方法 |
| ES2103906T3 (es) | 1992-02-27 | 1997-10-01 | Delmas Pierre Dr | Evaluacion de la fragilidad osea y prediccion del riesgo de fracturas osteoporoticas utilizando una determinacion cuantitativa de osteocalcina subcarboxilada circulante. |
| FI973371A0 (fi) * | 1997-08-15 | 1997-08-15 | Jukka Hellman | Nya isolerade peptider |
-
1999
- 1999-03-29 FI FI990693A patent/FI990693A0/fi unknown
-
2000
- 2000-03-20 DE DE60041534T patent/DE60041534D1/de not_active Expired - Lifetime
- 2000-03-20 ES ES00914195T patent/ES2320848T3/es not_active Expired - Lifetime
- 2000-03-20 WO PCT/FI2000/000227 patent/WO2000058732A1/en not_active Ceased
- 2000-03-20 AT AT00914195T patent/ATE422672T1/de not_active IP Right Cessation
- 2000-03-20 US US09/937,620 patent/US6967081B1/en not_active Expired - Fee Related
- 2000-03-20 EP EP00914195A patent/EP1166122B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FI990693A0 (fi) | 1999-03-29 |
| EP1166122A1 (de) | 2002-01-02 |
| EP1166122B1 (de) | 2009-02-11 |
| ES2320848T3 (es) | 2009-05-29 |
| US6967081B1 (en) | 2005-11-22 |
| WO2000058732A1 (en) | 2000-10-05 |
| ATE422672T1 (de) | 2009-02-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60223561D1 (de) | Verfahren zum nachweis von oxidativem stress sowie kit zur durchführung davon | |
| DE60239968D1 (de) | Sche | |
| WO2002063269A3 (en) | Layered calibration standard for tissue sampling | |
| DE60315373D1 (de) | Vorrichtung und Verfahren zur Bestimmung der Konzentration von Analyten | |
| ATE164943T1 (de) | Verfahren und vorrichtung zur bewertung der fitness von biopolymeren | |
| CY1111229T1 (el) | Μεθοδος προσδιορισμου ρευματοειδους αρθριτιδας με μετρηση αντι-ccp και ιντερλευκλινης 6 | |
| ATE461449T1 (de) | Verfahren zum nachweis von medizinisch relevanten zuständen in gelösten lbc-proben | |
| DK0682257T3 (da) | Fremgangsmåder til detektion af collagennedbrydning in vivo | |
| AU2003213594A1 (en) | Assays for cancer patient monitoring based on levels of analyte components of the plasminogen activator system in body fluid samples | |
| EP1381864A4 (de) | Candida-nachweis | |
| ATE511549T1 (de) | Kit zur messung der thrombinerzeugung in einer blut- oder plasmaprobe eines patienten | |
| TW200636076A (en) | Method for measuring resistance or sensitivity to docetaxel | |
| DE60041534D1 (de) | Verfahren zur vorhersage der wahrscheinlichkeit von knochenbrüchen mittels osteocalcin-messungen | |
| DE69821246D1 (de) | Testverfahren für collagenpeptid | |
| ATE333091T1 (de) | Verfahren zur messung von blutersatzstoffen | |
| ES2103906T3 (es) | Evaluacion de la fragilidad osea y prediccion del riesgo de fracturas osteoporoticas utilizando una determinacion cuantitativa de osteocalcina subcarboxilada circulante. | |
| ATE409314T1 (de) | Verfahren zur beurteilung rheumatoider arthritis durch messen von anti-ccp und serumamyloid a | |
| EP1476757A4 (de) | Verfahren und kit zur krebsvorhersage | |
| ATE412181T1 (de) | Verbessertes verfahren zur diagnose des akuten koronarsyndroms | |
| FR2831821B1 (fr) | Marqueur biologique des etats de stress, procede d'evaluation quantitative de presence de ce marqueur, et son utilisation pour la prevention du stress | |
| BRPI0415562A (pt) | reagente para avaliação diagnóstica e/ou prognóstica de carcinoma, métodos para determinação de p-lap que é um fator prognóstico em carcinoma, e para avaliação prognóstica de carcinoma, e, kit de imunoensaio para determinação da quantidade de p-lap presente em tecidos de carcinoma | |
| DE60323661D1 (de) | Quantifizierung von stressbelastung | |
| DE60330125D1 (de) | Screening-verfahren für gastritis | |
| EP1456645A4 (de) | Verfahren zur bestimmung der prognose von krebspatienten mittels tucan | |
| WO2005060627A3 (en) | Methods of assessing the risk of non-traumatic bone fracture |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |