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DE60041534D1 - Verfahren zur vorhersage der wahrscheinlichkeit von knochenbrüchen mittels osteocalcin-messungen - Google Patents

Verfahren zur vorhersage der wahrscheinlichkeit von knochenbrüchen mittels osteocalcin-messungen

Info

Publication number
DE60041534D1
DE60041534D1 DE60041534T DE60041534T DE60041534D1 DE 60041534 D1 DE60041534 D1 DE 60041534D1 DE 60041534 T DE60041534 T DE 60041534T DE 60041534 T DE60041534 T DE 60041534T DE 60041534 D1 DE60041534 D1 DE 60041534D1
Authority
DE
Germany
Prior art keywords
coc
toc
mean
person
ioc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60041534T
Other languages
English (en)
Inventor
Sanna-Maria Kaekonen
Heikki Luukinen
Kim Pettersson
Timo Loevgren
Kalervo H Vaeaenaenen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE60041534D1 publication Critical patent/DE60041534D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders
    • G01N2800/108Osteoporosis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/81Packaged device or kit

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
DE60041534T 1999-03-29 2000-03-20 Verfahren zur vorhersage der wahrscheinlichkeit von knochenbrüchen mittels osteocalcin-messungen Expired - Lifetime DE60041534D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI990693A FI990693A0 (fi) 1999-03-29 1999-03-29 Menetelmä luunmurtumien ennustamiseksi osteokalsiinimääritysten avulla
PCT/FI2000/000227 WO2000058732A1 (en) 1999-03-29 2000-03-20 Method for prediction of bone fractures by osteocalcin measurements

Publications (1)

Publication Number Publication Date
DE60041534D1 true DE60041534D1 (de) 2009-03-26

Family

ID=8554306

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60041534T Expired - Lifetime DE60041534D1 (de) 1999-03-29 2000-03-20 Verfahren zur vorhersage der wahrscheinlichkeit von knochenbrüchen mittels osteocalcin-messungen

Country Status (7)

Country Link
US (1) US6967081B1 (de)
EP (1) EP1166122B1 (de)
AT (1) ATE422672T1 (de)
DE (1) DE60041534D1 (de)
ES (1) ES2320848T3 (de)
FI (1) FI990693A0 (de)
WO (1) WO2000058732A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040259167A1 (en) * 1997-08-15 2004-12-23 Jukka Hellman Isolated osteocalcin fragments
CA2378711A1 (en) 1999-08-14 2001-02-22 November Aktiengesellschaft Gesellschaft Fur Molekulare Medizin Method for indirectly determining the blood-clotting status
GB0107393D0 (en) * 2001-03-23 2001-05-16 Osteometer Biotech As A method of assaying osteocalcin fragments in body fluids a test kit and means for carrying out the method and use of the method to monitor bone resorption
WO2008088401A2 (en) * 2006-09-13 2008-07-24 The Trustees Of Columbia University In The City Of New York Methods for identifying, or assaying for agents that increase beta-cell proliferation, insulin secretion, insulin sensitivity, glucose tolerance and decreases fat mass
EP2326664A2 (de) * 2008-08-27 2011-06-01 Universidade Do Algarve Ein gammacarboxyglutamatreiches protein, verfahren und assays zu seinem nachweis, seiner aufreinigung und seiner quantifizierung und anwendungen davon
CN120699147B (zh) * 2025-07-04 2025-12-05 东方海洋(北京)医学研究院有限公司 完全羧基化骨钙素特异性单克隆抗体及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0739439B2 (ja) * 1989-03-16 1995-05-01 寳酒造株式会社 モノクローナル抗体及びその使用方法
ES2103906T3 (es) 1992-02-27 1997-10-01 Delmas Pierre Dr Evaluacion de la fragilidad osea y prediccion del riesgo de fracturas osteoporoticas utilizando una determinacion cuantitativa de osteocalcina subcarboxilada circulante.
FI973371A0 (fi) * 1997-08-15 1997-08-15 Jukka Hellman Nya isolerade peptider

Also Published As

Publication number Publication date
FI990693A0 (fi) 1999-03-29
EP1166122A1 (de) 2002-01-02
EP1166122B1 (de) 2009-02-11
ES2320848T3 (es) 2009-05-29
US6967081B1 (en) 2005-11-22
WO2000058732A1 (en) 2000-10-05
ATE422672T1 (de) 2009-02-15

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