[go: up one dir, main page]

DE60039238D1 - C-2-modifizierte erythromycinderivate - Google Patents

C-2-modifizierte erythromycinderivate

Info

Publication number
DE60039238D1
DE60039238D1 DE60039238T DE60039238T DE60039238D1 DE 60039238 D1 DE60039238 D1 DE 60039238D1 DE 60039238 T DE60039238 T DE 60039238T DE 60039238 T DE60039238 T DE 60039238T DE 60039238 D1 DE60039238 D1 DE 60039238D1
Authority
DE
Germany
Prior art keywords
compound
formula
erythromycin derivatives
bacterial infections
treating bacterial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60039238T
Other languages
English (en)
Inventor
Zhenkun Ma
Yat Sun Or
Ly Tam Phan
Suoming Zhang
Richard F Clark
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE60039238D1 publication Critical patent/DE60039238D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE60039238T 1999-05-14 2000-05-04 C-2-modifizierte erythromycinderivate Expired - Fee Related DE60039238D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/312,517 US6355620B1 (en) 1999-05-14 1999-05-14 C-2 modified erythromycin derivatives
PCT/US2000/012202 WO2000069875A1 (en) 1999-05-14 2000-05-04 C-2 modified erythromycin derivatives

Publications (1)

Publication Number Publication Date
DE60039238D1 true DE60039238D1 (de) 2008-07-31

Family

ID=23211820

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60039238T Expired - Fee Related DE60039238D1 (de) 1999-05-14 2000-05-04 C-2-modifizierte erythromycinderivate

Country Status (11)

Country Link
US (1) US6355620B1 (de)
EP (1) EP1181299B1 (de)
JP (1) JP2002544284A (de)
AT (1) ATE398627T1 (de)
CA (1) CA2372270C (de)
DE (1) DE60039238D1 (de)
DK (1) DK1181299T3 (de)
ES (1) ES2307511T3 (de)
MX (1) MXPA01011633A (de)
PT (1) PT1181299E (de)
WO (1) WO2000069875A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE256694T1 (de) 1999-01-27 2004-01-15 Pfizer Prod Inc Ketolid-antibiotika
IL145739A0 (en) * 1999-05-24 2002-07-25 Pfizer Prod Inc 13-methyl-erythromycin derivatives
TR200401847T4 (tr) * 2000-06-30 2004-09-21 Pfizer Products Inc. Makrolit antibiyotikler.
ES2275621T3 (es) * 2000-12-21 2007-06-16 Glaxo Group Limited Antibioticos macrolidos.
DE10122139A1 (de) * 2001-05-08 2002-11-21 Daniel Swarovski Verfahren und Vorrichtung zur Bestimmung der Verteilung von Inhaltsstoffen in fluiden Medien
CN1585775A (zh) 2001-12-05 2005-02-23 奥索-麦克尼尔药品公司 可用作抗菌药的红霉素的6－o－酰基酮内酯衍生物
US6841664B2 (en) * 2002-07-25 2005-01-11 Enanra Pharmaceuticals, Inc. 6,11-4-carbon bridged ketolides
US7273853B2 (en) * 2002-05-13 2007-09-25 Enanta Pharmaceuticals, Inc. 6-11 bicyclic ketolide derivatives
US7910558B2 (en) * 2002-05-13 2011-03-22 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
US7163924B2 (en) 2003-04-25 2007-01-16 Chiron Corporation Ketolide derivatives
US7414030B2 (en) * 2004-01-07 2008-08-19 Enanta Pharmaceuticals, Inc. 6-11 Bicyclic erythromycin derivatives
WO2005070113A2 (en) * 2004-01-09 2005-08-04 Enanta Pharmaceuticals, Inc. 9n-substituted 6-11 bicyclic erythromycin derivatives
US7384921B2 (en) * 2004-02-20 2008-06-10 Enanta Pharmaceuticals, Inc. Polymorphic forms of 6-11 bicyclic ketolide derivatives
US20050250713A1 (en) * 2004-04-26 2005-11-10 Bin Zhu 11,12-Cyclic thiocarbamate macrolide antibacterial agents
WO2006065743A2 (en) * 2004-12-13 2006-06-22 Enanta Pharmaceuticals, Inc. Tetracylic bicyclolides
CN101120011A (zh) * 2004-12-21 2008-02-06 辉瑞产品公司 大环内酯
US7384922B2 (en) * 2005-05-04 2008-06-10 Enanta Pharmaceuticals, Inc. 6-11 bridged oxime erythromycin derivatives
US20060252710A1 (en) * 2005-05-04 2006-11-09 Guoqiang Wang 6-11 Bridged oxime erythromycin derivatives
WO2009019868A1 (ja) 2007-08-06 2009-02-12 Taisho Pharmaceutical Co., Ltd. １０ａ、１２位架橋型１０ａ－アザライド化合物
US8354383B2 (en) * 2007-09-17 2013-01-15 Enanta Pharmaceuticals, Inc. 6,11-bridged biaryl macrolides
US8273720B2 (en) * 2007-09-17 2012-09-25 Enanta Pharmaceuticals, Inc. 6,11-bicyclolides: bridged biaryl macrolide derivatives
KR101223158B1 (ko) * 2007-09-17 2013-01-17 이난타 파마슈티칼스, 인코포레이티드 6,11-다리걸친 바이아릴 매크로라이드
TW200946109A (en) * 2008-05-09 2009-11-16 Enanta Pharm Inc Anti-bacterial activity of 9-hydroxy derivatives 6, 11-bicyclolides
US8299035B2 (en) 2008-05-15 2012-10-30 Taisho Pharmaceutucal Co., Ltd. 10a-azalide compound having 4-membered ring structure
CN104650166B (zh) * 2014-11-17 2017-12-05 广东东阳光药业有限公司 一种大环内酯的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of erythromycin derivatives
US5403923A (en) 1990-11-28 1995-04-04 Taisho Pharmaceutical Co., Ltd. 6-0-methylerythromycin A derivatives
DK0638585T3 (da) 1992-04-22 1996-12-02 Taisho Pharmaceutical Co Ltd 5-O-desosaminylerythronolid-A-derivater
FR2742757B1 (fr) 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US5940488A (en) * 1996-11-15 1999-08-17 Active Voice Corporation Telecommunication management system and user interface
ES2217579T3 (es) * 1997-09-30 2004-11-01 Abbott Laboratories Derivados de eritromicina cetolidos, modificados en n-3 y sustituidos en o-6, que tiene una actividad antibacteriana.

Also Published As

Publication number Publication date
CA2372270A1 (en) 2000-11-23
WO2000069875A1 (en) 2000-11-23
DK1181299T3 (da) 2008-10-27
MXPA01011633A (es) 2002-07-30
PT1181299E (pt) 2008-09-18
ATE398627T1 (de) 2008-07-15
EP1181299A1 (de) 2002-02-27
WO2000069875A9 (en) 2002-02-21
ES2307511T3 (es) 2008-12-01
EP1181299B1 (de) 2008-06-18
CA2372270C (en) 2008-07-22
US6355620B1 (en) 2002-03-12
JP2002544284A (ja) 2002-12-24

Similar Documents

Publication Publication Date Title
ATE398627T1 (de) C-2-modifizierte erythromycinderivate
WO2004062601A3 (en) Antibacterial agents
CA2392973A1 (en) Benzoimidazole derivatives useful as antiproliferative agents
TR199901127T2 (xx) Antibakteriyel etkili 6-O-ikameli ketolitler.
NO996108L (no) 9-oksinerytromycinderivater
CA2413424A1 (en) Substituted bicyclic derivatives for the treatment of abnormal cell growth
DK1021456T3 (da) Makrocykliske derivater af erythromysin A og B med 13-leddet ring
IL165715A0 (en) 2-ureido-6-heteroaryl-3h-benzoimidazole-4-carboxylic acid derivatives, pharmaceutical compositions containing the same and methods for the preparation thereof
CA2478374A1 (en) N3 alkylated benzimidazole derivatives as mek inhibitors
AP9801378A0 (en) 9-amino-3- keto erythromycin derivatives.
TR200103395T2 (tr) 13-metil eritromisin türevleri.
WO2004096823A3 (en) Novel ketolide derivatives
MX2009006334A (es) Derivados de heteroaril-pirrolidinil- y -piperidinil-cetona.
NO20052074L (no) Substituerte benzoksazinoner og anvendelser derav.
DK0992509T3 (da) Nye makrolid-derivater
GEP20084437B (en) Novel lincomycin derivatives possessing antimicrobial activity
NO20054135L (no) Kipolinon/benzoksazin derivater og anvendelser derav
BR9708929A (pt) Composto composição farmacêutica e processos para controlar uma infecção bacteriana em um mamífero e para preparar compostos de macrólidos
EP1109560A4 (de) Als inhibitoren der aicarftnützliche verbindungen
AP9801377A0 (en) Tricyclic erythromycin derivatives.
WO2003057213A3 (en) Cyclohexano- and cycloheptapyrazole derivative compounds, for use in diseases associated with the 5-ht2c receptor
AP2001002325A0 (en) Novel crystalline forms of a macrolide antibiotic
WO2002018353A3 (en) Oxazolidinone chemotherapeutic agents
TR200201145T2 (tr) Hidromisin türevleri
NZ515278A (en) Halo derivatives of 9-deoxo-9a-aza-9a- homerythromycin A their salts and preparation process

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee