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DE60031418D1 - 15571, ein neues gpcr-ähnliches molekül der secretin-ähnlichen familie und dessen verwendungen - Google Patents

15571, ein neues gpcr-ähnliches molekül der secretin-ähnlichen familie und dessen verwendungen

Info

Publication number
DE60031418D1
DE60031418D1 DE60031418T DE60031418T DE60031418D1 DE 60031418 D1 DE60031418 D1 DE 60031418D1 DE 60031418 T DE60031418 T DE 60031418T DE 60031418 T DE60031418 T DE 60031418T DE 60031418 D1 DE60031418 D1 DE 60031418D1
Authority
DE
Germany
Prior art keywords
gpcr
similar
nucleic acid
proteins
secretin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60031418T
Other languages
English (en)
Other versions
DE60031418T2 (de
Inventor
R Hodge
Clare Lloyd
S Weich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Millennium Pharmaceuticals Inc
Original Assignee
Millennium Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharmaceuticals Inc filed Critical Millennium Pharmaceuticals Inc
Publication of DE60031418D1 publication Critical patent/DE60031418D1/de
Application granted granted Critical
Publication of DE60031418T2 publication Critical patent/DE60031418T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Emergency Medicine (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
DE60031418T 1999-08-03 2000-08-03 15571, ein neues gpcr-ähnliches molekül der secretin-ähnlichen familie und dessen verwendungen Expired - Lifetime DE60031418T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US14691699P 1999-08-03 1999-08-03
US146916P 1999-08-03
US51578100A 2000-02-29 2000-02-29
US515781 2000-02-29
PCT/US2000/021278 WO2001009328A1 (en) 1999-08-03 2000-08-03 15571, a novel gpcr-like molecule of the secretin-like family and uses thereof

Publications (2)

Publication Number Publication Date
DE60031418D1 true DE60031418D1 (de) 2006-11-30
DE60031418T2 DE60031418T2 (de) 2007-08-23

Family

ID=26844411

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60031418T Expired - Lifetime DE60031418T2 (de) 1999-08-03 2000-08-03 15571, ein neues gpcr-ähnliches molekül der secretin-ähnlichen familie und dessen verwendungen

Country Status (8)

Country Link
US (1) US6733990B1 (de)
EP (1) EP1208196B1 (de)
JP (1) JP2003506042A (de)
AT (1) ATE342979T1 (de)
AU (1) AU6517400A (de)
DE (1) DE60031418T2 (de)
ES (1) ES2272309T3 (de)
WO (1) WO2001009328A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2367822A (en) * 2000-06-19 2002-04-17 Smithkline Beecham Corp CD97 polypeptides
WO2002016600A2 (en) * 2000-08-25 2002-02-28 Curagen Corporation Novel proteins and nucleic acids encoding same
FR2823762A1 (fr) * 2001-04-24 2002-10-25 Servier Lab Sequence d'acides nucleiques codant un nouveau recepteur couple aux porteines g et utilisations
JP2003047472A (ja) * 2001-08-01 2003-02-18 Takeda Chem Ind Ltd 新規ｇタンパク質共役型レセプタータンパク質およびそのｄｎａ
EP1506412A1 (de) * 2002-05-08 2005-02-16 Bayer HealthCare AG Diagnostika und therapeutika für krankheiten, die mit dem vasoactive intestinal peptide receptor 2 (vpac2) assoziiert sind
WO2004000883A1 (en) * 2002-06-24 2003-12-31 Bayer Healthcare Ag Regulation of human growth hormone-releasing hormone receptor
US8084575B2 (en) 2002-12-20 2011-12-27 Julius-Maximilians-Universitat Millisecond activation switch for seven-transmembrane proteins
WO2004071393A2 (en) * 2003-02-13 2004-08-26 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with glucagon-like peptide 1 receptor (glp1r)
WO2004071396A2 (en) * 2003-02-17 2004-08-26 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with parathyroid hormone receptor 2 (pthr2)
WO2004073587A2 (en) * 2003-02-19 2004-09-02 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with parathyroid hormone receptor 1 (pthr1)
US20100278810A1 (en) * 2007-05-24 2010-11-04 Frank Kuhnert Methods of Modulating Angiogenesis
WO2013126590A2 (en) * 2012-02-21 2013-08-29 Baxter International Inc. Pharmaceutical composition comprising cd34+ cells
CN110694071B (zh) * 2017-08-21 2020-09-22 武汉大学 Gpr31抑制剂在制备治疗心肌肥厚及相关疾病药物中的应用

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5155218A (en) 1990-05-08 1992-10-13 Neurogenetic Corporation Dna encoding human 5-ht1d receptors
US5756460A (en) 1991-03-06 1998-05-26 Garvan Institute Of Medical Research Human galanin, CDNA clones encoding human galanin and a method of producing human galanin
US5576296A (en) 1991-05-15 1996-11-19 Aktiebolaget Astra Galanin antagonist
GB9214857D0 (en) 1992-07-13 1992-08-26 Medical Res Council Human nucleic acid fragments and their use
WO1996039442A1 (en) 1995-06-06 1996-12-12 Human Genome Sciences, Inc. G-protein receptor htnad29
GB9614823D0 (en) 1996-07-15 1996-09-04 Pharmacia Spa Recombinant kynurenine-3-hydroxylase enzyme and process for its preparation
EP0925358B1 (de) 1996-09-10 2007-04-25 Theodor-Kocher Institute Cxcr3 chemokine rezeptor, antikoerper, nukleinsaeure und deren verfahren zur anwendung
US6329197B2 (en) 1996-10-09 2001-12-11 Synaptic Pharmaceutical Corporation DNA encoding galanin GALR3 receptors and uses thereof
US6403305B1 (en) 1997-02-06 2002-06-11 Cornell Research Foundation, Inc. Methods of identifying peptide agonists or negative antagonists of a G protein coupled receptor
EP0973896A2 (de) * 1997-04-10 2000-01-26 Genetics Institute, Inc. Sekretierte exprimierte sequenzkennzeichen (sests)
US5948639A (en) 1997-04-10 1999-09-07 Millennium Pharmaceuticals, Inc. TGF-β pathway genes
US5912144A (en) 1997-04-24 1999-06-15 Incyte Pharmaceuticals, Inc. Edg-1-receptor homolog
US6060272A (en) 1997-05-07 2000-05-09 Human Genome Sciences, Inc. Human G-protein coupled receptors
US6020158A (en) 1997-05-22 2000-02-01 Allelix Biopharmaceuticals, Inc. Isolated polynucleotide for novel G-protein coupled receptor
US6063596A (en) 1997-12-11 2000-05-16 Incyte Pharmaceuticals, Inc. G-protein coupled receptors associated with immune response
WO1999033982A2 (en) 1997-12-23 1999-07-08 Chiron Corporation Human genes and gene expression products i
AU1955899A (en) 1997-12-30 1999-07-26 Nps Allelix Corp. Mammalian edg-7 receptor homologs
EP1053319A2 (de) 1998-01-28 2000-11-22 Chiron Corporation Menschliche gene und expressionsprodukte ii
EP1053245A4 (de) 1998-02-09 2002-04-17 Human Genome Sciences Inc 45 menschliche sekretierte proteine
JP2002504331A (ja) 1998-02-19 2002-02-12 スミスクライン ビーチャム コーポレーション Ｇタンパク質共役型受容体ＡｍＭａｉｄ
ES2300074T3 (es) 1998-03-12 2008-06-01 Astellas Pharma Inc. Nuevas proteinas de receptores copulados a proteina g.
DE19817948A1 (de) 1998-04-17 1999-10-21 Metagen Gesellschaft Fuer Genomforschung Mbh Menschliche Nukleinsäuresequenzen aus Endometrium-Tumor
JP2002512780A (ja) 1998-04-24 2002-05-08 スミスクライン ビーチャム コーポレーション 新規７ｔｍ受容体ａｘｏｒ−２のクローニング
WO1999057270A2 (en) 1998-05-01 1999-11-11 Incyte Pharmaceuticals, Inc. Human receptor molecules

Also Published As

Publication number Publication date
EP1208196A4 (de) 2003-07-09
EP1208196B1 (de) 2006-10-18
ATE342979T1 (de) 2006-11-15
AU6517400A (en) 2001-02-19
WO2001009328A9 (en) 2002-08-08
DE60031418T2 (de) 2007-08-23
ES2272309T3 (es) 2007-05-01
WO2001009328A8 (en) 2003-10-23
JP2003506042A (ja) 2003-02-18
US6733990B1 (en) 2004-05-11
WO2001009328A1 (en) 2001-02-08
EP1208196A1 (de) 2002-05-29

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