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DE60027761D1 - Komprimierte zubereitung enthaltend nichtsteroidale entzündungshemmer - Google Patents

Komprimierte zubereitung enthaltend nichtsteroidale entzündungshemmer

Info

Publication number
DE60027761D1
DE60027761D1 DE60027761T DE60027761T DE60027761D1 DE 60027761 D1 DE60027761 D1 DE 60027761D1 DE 60027761 T DE60027761 T DE 60027761T DE 60027761 T DE60027761 T DE 60027761T DE 60027761 D1 DE60027761 D1 DE 60027761D1
Authority
DE
Germany
Prior art keywords
teroidal
preparation containing
containing non
inflammation inhibitors
compressed preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60027761T
Other languages
English (en)
Other versions
DE60027761T2 (de
Inventor
Robert Arthur Sherry
Tracey Jane Rhoades
Frederick Raymond Higton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reckitt Benckiser Healthcare UK Ltd
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9929078.5A external-priority patent/GB9929078D0/en
Priority claimed from GBGB9929077.7A external-priority patent/GB9929077D0/en
Application filed by Boots Co PLC filed Critical Boots Co PLC
Application granted granted Critical
Publication of DE60027761D1 publication Critical patent/DE60027761D1/de
Publication of DE60027761T2 publication Critical patent/DE60027761T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DE60027761T 1999-12-09 2000-11-30 Komprimierte zubereitung enthaltend nichtsteroidale entzündungshemmer Expired - Lifetime DE60027761T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9929078 1999-12-09
GB9929077 1999-12-09
GBGB9929078.5A GB9929078D0 (en) 1999-12-09 1999-12-09 Therapeutic agents
GBGB9929077.7A GB9929077D0 (en) 1999-12-09 1999-12-09 Therapeutic agents
PCT/EP2000/012193 WO2001041733A2 (en) 1999-12-09 2000-11-30 Compressed tablet composition comprising a nsaid

Publications (2)

Publication Number Publication Date
DE60027761D1 true DE60027761D1 (de) 2006-06-08
DE60027761T2 DE60027761T2 (de) 2007-01-25

Family

ID=26316111

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60027761T Expired - Lifetime DE60027761T2 (de) 1999-12-09 2000-11-30 Komprimierte zubereitung enthaltend nichtsteroidale entzündungshemmer

Country Status (27)

Country Link
US (1) US8124124B2 (de)
EP (1) EP1235558B1 (de)
JP (1) JP4040878B2 (de)
KR (1) KR20020082464A (de)
CN (1) CN100346774C (de)
AR (1) AR026917A1 (de)
AT (1) ATE324868T1 (de)
AU (1) AU776308B2 (de)
BG (1) BG66007B1 (de)
BR (1) BR0016236A (de)
CA (1) CA2393585C (de)
CY (1) CY1106136T1 (de)
CZ (1) CZ300558B6 (de)
DE (1) DE60027761T2 (de)
DK (1) DK1235558T3 (de)
ES (1) ES2263510T3 (de)
HK (1) HK1046644B (de)
HU (1) HU227045B1 (de)
IL (2) IL150030A0 (de)
MX (1) MXPA02005663A (de)
NO (1) NO332259B1 (de)
NZ (1) NZ519485A (de)
PL (1) PL201223B1 (de)
PT (1) PT1235558E (de)
RU (1) RU2246294C2 (de)
SK (1) SK285706B6 (de)
WO (1) WO2001041733A2 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0113839D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
GB0113841D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
GB0113843D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
PL373914A1 (en) * 2002-02-01 2005-09-19 Pfizer Products Inc. Immediate release dosage forms containing solid drug dispersions
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
GB0423103D0 (en) * 2004-10-19 2004-11-17 Boots Healthcare Int Ltd Therapeutic agents
US8846088B2 (en) * 2005-02-03 2014-09-30 Takeda Nycomed As Melt granulation of a composition containing a calcium-containing compound
DE102005037630A1 (de) 2005-08-09 2007-02-15 Glatt Gmbh Verfahren zur Herstellung von Teilchen aus pharmazeutischen Substanzen, Teilchen aus pharmazeutischen Substanzen sowie deren Verwendung
GB0519350D0 (en) * 2005-09-22 2005-11-02 Boots Healthcare Int Ltd Therapeutic agents
US20080292702A1 (en) * 2005-12-16 2008-11-27 Hanmi Pharm. Co. Ltd. Solid Dispersion Comprising An Active Ingredient Having A Low Melting Point And Tablet For Oral Administration Comprising Same
EP1905427B1 (de) 2006-09-28 2010-11-24 Losan Pharma GmbH Schnell lösliche Formulierung von nichtsteroidalen Antiphlogistika
GB2447898B (en) * 2007-03-24 2011-08-17 Reckitt Benckiser Healthcare A tablet having improved stability with at least two actives
DE102008048729A1 (de) * 2008-09-24 2010-03-25 Add Technologies Ltd Advanced Drug Delivery Multipartikuläre Tabletten und Verfahren zur deren Herstellung
US8662705B2 (en) 2010-03-30 2014-03-04 Virwall Systems, Inc. Flexible ultraviolet LED sanitizing apparatus
US20130108699A1 (en) * 2010-04-26 2013-05-02 Jose Antonio Matji Tuduri Highly dispersible granulate for the preparation of formulations of high dosage active substances and procedure for obtaining high dosage active substances thereof
JP5750856B2 (ja) * 2010-10-04 2015-07-22 ライオン株式会社 固形医薬組成物及び医薬製剤
JP5974469B2 (ja) * 2010-12-24 2016-08-23 ライオン株式会社 錠剤の製造方法
WO2013095315A1 (en) * 2011-12-19 2013-06-27 Mahmut Bilgic Formulations comprising dexketoprofen (particle size 300-2500 micrometer)
EP2793853B1 (de) * 2011-12-23 2015-12-16 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Pharmazeutische formulierungen aus flurbiprofen und glucosamin
US20140163109A1 (en) 2012-03-26 2014-06-12 Glatt Ag Taste-masked ibupropen granules
PL2919903T3 (pl) 2012-11-14 2020-12-14 W.R. Grace & Co. - Conn. Kompozycje zawierające materiał biologicznie aktywny i nieuporządkowany tlenek nieorganiczny
EP2845850A1 (de) 2013-09-10 2015-03-11 ObsEva S.A. Pyrrolidinderivate als Oxytocin/Vasopressin-V1a-Rezeptorantagonisten
EP2886107A1 (de) 2013-12-17 2015-06-24 ObsEva S.A. Orale Formulierungen von Pyrrolydinderivaten
CZ20131023A3 (cs) * 2013-12-18 2014-08-27 Technická univerzita v Liberci Způsob rozvádění příze při jejím navíjení na cívku uloženou v navíjecím ústrojí pracovního místa textilního stroje a zařízení k jeho provádění
EA201891873A1 (ru) 2014-07-02 2019-04-30 Обсева Са Кристаллический о-метилоксим (3z,5s)-5-(гидроксиметил)-1-[(2'-метил-1,1'-бифенил-4-ил)карбонил]пирролидин-3-он, полезный в способах лечения состояний, связанных с активностью ot-r
US20190022013A1 (en) * 2015-12-19 2019-01-24 First Time Us Generics Llc Soft-chew tablet pharmaceutical formulations
CA2937365C (en) 2016-03-29 2018-09-18 F. Hoffmann-La Roche Ag Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same
BE1023057B1 (nl) * 2016-06-06 2016-11-16 Nordic Specialty Pharma Bvba Ibuprofen tablet
JP6792235B2 (ja) * 2016-09-05 2020-11-25 株式会社アクロエッジ 凝集体の凝集度の測定方法及び凝集度測定装置

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56120616A (en) * 1980-02-27 1981-09-22 Kaken Pharmaceut Co Ltd Ibuprofen-containing granule, its preparation, and internal medicine comprising it
US4609675A (en) * 1984-08-17 1986-09-02 The Upjohn Company Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing
US5240712A (en) * 1987-07-17 1993-08-31 The Boots Company Plc Therapeutic agents
SE463541B (sv) * 1987-08-31 1990-12-10 Lejus Medical Ab Granulaer produkt oeverdragen av en smaelta av sig sjaelv samt foerfarande foer dess framstaellning
DE3833448A1 (de) * 1988-10-01 1990-04-12 Hoechst Ag Verfahren zur gewinnung von ibuprofen fuer die direkttablettierung
JPH05506011A (ja) 1990-04-11 1993-09-02 ジ・アップジョン・カンパニー 流動床コーティングによるイブプロフェンの味覚マスキング
CA2061520C (en) * 1991-03-27 2003-04-22 Lawrence J. Daher Delivery system for enhanced onset and increased potency
DK138592D0 (da) 1992-11-17 1992-11-17 Nycomed Dak As Tabletter
AT401871B (de) * 1994-01-28 1996-12-27 Gebro Broschek Gmbh Verfahren zur herstellung von s(+)-ibuprofen- partikeln mit verbesserten fliesseigenschaften und deren verwendung zur arzneimittelherstellung
PL179910B1 (pl) * 1994-05-06 2000-11-30 Pfizer Postac dawkowania o kontrolowanym uwalnianiu zawierajaca azytromycyne PL PL PL PL PL PL PL PL
DE4418837A1 (de) * 1994-05-30 1995-12-07 Bayer Ag Thermisches Granulierverfahren
GB9702392D0 (en) * 1997-02-06 1997-03-26 Boots Co Plc Therapeutic agents
GB9710521D0 (en) 1997-05-22 1997-07-16 Boots Co Plc Process
DE19721467A1 (de) * 1997-05-22 1998-11-26 Basf Ag Verfahren zur Herstellung kleinteiliger Zubereitungen biologisch aktiver Stoffe
CA2214895C (en) * 1997-09-19 1999-04-20 Bernard Charles Sherman Improved pharmaceutical composition comprising fenofibrate
IE980115A1 (en) * 1998-02-16 2000-02-09 Biovail Internat Ltd Solubilizing delivery systems and method of manufacture

Also Published As

Publication number Publication date
NO20022692L (no) 2002-08-07
JP2003516341A (ja) 2003-05-13
AU776308B2 (en) 2004-09-02
DE60027761T2 (de) 2007-01-25
PT1235558E (pt) 2006-09-29
NZ519485A (en) 2004-02-27
DK1235558T3 (da) 2006-10-09
CZ20021971A3 (cs) 2002-11-13
MXPA02005663A (es) 2002-09-02
IL150030A (en) 2008-06-05
CY1106136T1 (el) 2011-06-08
CA2393585C (en) 2007-07-03
JP4040878B2 (ja) 2008-01-30
SK8022002A3 (en) 2003-07-01
PL355491A1 (en) 2004-05-04
WO2001041733A2 (en) 2001-06-14
AR026917A1 (es) 2003-03-05
HK1046644A1 (en) 2003-01-24
ATE324868T1 (de) 2006-06-15
CZ300558B6 (cs) 2009-06-17
BG66007B1 (bg) 2010-10-29
US8124124B2 (en) 2012-02-28
CA2393585A1 (en) 2001-06-14
KR20020082464A (ko) 2002-10-31
ES2263510T3 (es) 2006-12-16
NO332259B1 (no) 2012-08-13
RU2246294C2 (ru) 2005-02-20
US20030203026A1 (en) 2003-10-30
CN1433300A (zh) 2003-07-30
BR0016236A (pt) 2002-12-24
WO2001041733A3 (en) 2001-11-15
HUP0203553A3 (en) 2004-06-28
HUP0203553A2 (hu) 2004-05-28
EP1235558A2 (de) 2002-09-04
AU3006001A (en) 2001-06-18
SK285706B6 (sk) 2007-06-07
HU227045B1 (en) 2010-05-28
AU2004231245A1 (en) 2004-12-23
EP1235558B1 (de) 2006-05-03
PL201223B1 (pl) 2009-03-31
IL150030A0 (en) 2002-12-01
BG106839A (bg) 2003-03-31
RU2002118210A (ru) 2004-02-20
HK1046644B (en) 2006-11-10
CN100346774C (zh) 2007-11-07
NO20022692D0 (no) 2002-06-06

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: RECKITT BENCKISER HEALTHCARE (UK) LTD., SLOUGH, BE

8364 No opposition during term of opposition