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DE60022684D1 - Verfahren zur herstellug von 6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-(n,n-dimethylacetamid) und zwischenprodukte - Google Patents

Verfahren zur herstellug von 6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-(n,n-dimethylacetamid) und zwischenprodukte

Info

Publication number
DE60022684D1
DE60022684D1 DE60022684T DE60022684T DE60022684D1 DE 60022684 D1 DE60022684 D1 DE 60022684D1 DE 60022684 T DE60022684 T DE 60022684T DE 60022684 T DE60022684 T DE 60022684T DE 60022684 D1 DE60022684 D1 DE 60022684D1
Authority
DE
Germany
Prior art keywords
methyl
lower alkyl
formula
imidazo
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60022684T
Other languages
English (en)
Other versions
DE60022684T2 (de
Inventor
Laszlo Pongo
Jozsef Reiter
Gyula Simig
Peter Toempe
Fekete Valeria Hoffmanne
Endre Rivo
Laszlo Koncz
Donath Gyoergyi Vereczkeyne
Kalman Nagy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU9904379A external-priority patent/HU227358B1/hu
Priority claimed from HU9904377A external-priority patent/HUP9904377A2/hu
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Pharmaceuticals PLC filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of DE60022684D1 publication Critical patent/DE60022684D1/de
Application granted granted Critical
Publication of DE60022684T2 publication Critical patent/DE60022684T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE60022684T 1999-11-22 2000-11-22 Verfahren zur Herstellung von 6-Methyl-2-(4-methyl-phenyl)-imidazo [1,2-A]pyridin-3-(N,N-dimethyl-acetamid) und Zwischenprodukte Expired - Fee Related DE60022684T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
HU9904379 1999-11-22
HU9904379A HU227358B1 (en) 1999-11-22 1999-11-22 Novel process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyrimidyne-3-(n,n-dimethyl-acetamide)
HU9904377A HUP9904377A2 (en) 1999-11-22 1999-11-22 6-methyl-2-(4-methyl-phenyl)-imidazole-[1,2-a]pyrimidine-3-acetic acid-esters and process for their preparation
HU9904377 1999-11-22
PCT/HU2000/000120 WO2001038327A2 (en) 1999-11-22 2000-11-22 Process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyrimidine-3-(n,n-dimethyl-acetamide) and intermediates

Publications (2)

Publication Number Publication Date
DE60022684D1 true DE60022684D1 (de) 2005-10-20
DE60022684T2 DE60022684T2 (de) 2006-06-29

Family

ID=90000034

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60022684T Expired - Fee Related DE60022684T2 (de) 1999-11-22 2000-11-22 Verfahren zur Herstellung von 6-Methyl-2-(4-methyl-phenyl)-imidazo [1,2-A]pyridin-3-(N,N-dimethyl-acetamid) und Zwischenprodukte

Country Status (15)

Country Link
EP (1) EP1259509B1 (de)
JP (1) JP2003518016A (de)
KR (1) KR100656636B1 (de)
CN (1) CN1227252C (de)
AT (1) ATE304540T1 (de)
AU (1) AU1873901A (de)
CZ (1) CZ300711B6 (de)
DE (1) DE60022684T2 (de)
DK (1) DK1259509T3 (de)
ES (1) ES2248154T3 (de)
HR (1) HRP20020471B1 (de)
PL (1) PL354366A1 (de)
RU (1) RU2254334C2 (de)
SK (1) SK7122002A3 (de)
WO (1) WO2001038327A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2509561A1 (en) 2002-12-18 2004-07-15 Mallinckrodt Inc. Synthesis of heteroaryl acetamides
WO2004087703A1 (en) * 2003-03-12 2004-10-14 Sun Pharmaceutical Industries Limited Process for the preparation of n,n,6-trimethyl-2-(4-methylphenyl)-imidazo[1,2-a]pyridine-3-acetamide
PL2446996T3 (pl) 2005-05-26 2017-10-31 Alfa Laval Corp Ab Twardo lutowany płytowy wymiennik ciepła ze stali nierdzewnej z materiałem lutującym ze stali nierdzewnej
US20080293946A1 (en) * 2005-10-03 2008-11-27 Cheng Brian K Process for Preparing Zolpidem Hemitartrate and Tartrate Polymorphs
KR101008674B1 (ko) * 2008-01-25 2011-01-18 주식회사 이화창 컨테이너 및 그 컨테이너를 구비한 두피 마사지기
CN103360387B (zh) * 2012-03-28 2016-12-14 江苏豪森药业集团有限公司 一种制备化合物唑吡坦的方法
CN114105974A (zh) * 2020-08-27 2022-03-01 鲁南制药集团股份有限公司 一种唑吡坦的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2151834B1 (es) * 1998-08-06 2001-08-16 Sint Quimica Sa Procedimiento para preparar n,n,6-trimetil-2-(4-metilfenil)-imidazo-(1,2-a)-piridina-3-acetamida y sus sales.
DK1163241T3 (da) * 1999-03-25 2005-10-10 Synthon Bv Zolpidemsalte

Also Published As

Publication number Publication date
CN1413212A (zh) 2003-04-23
WO2001038327A2 (en) 2001-05-31
SK7122002A3 (en) 2002-10-08
CZ20021713A3 (cs) 2002-08-14
EP1259509A1 (de) 2002-11-27
CN1227252C (zh) 2005-11-16
ATE304540T1 (de) 2005-09-15
EP1259509B1 (de) 2005-09-14
AU1873901A (en) 2001-06-04
KR100656636B1 (ko) 2006-12-11
KR20020052213A (ko) 2002-07-02
ES2248154T3 (es) 2006-03-16
CZ300711B6 (cs) 2009-07-22
DK1259509T3 (da) 2006-01-16
RU2254334C2 (ru) 2005-06-20
WO2001038327A3 (en) 2002-09-12
PL354366A1 (en) 2004-01-12
HRP20020471A2 (en) 2005-10-31
JP2003518016A (ja) 2003-06-03
HRP20020471B1 (en) 2007-12-31
DE60022684T2 (de) 2006-06-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee