DE60020348D1 - Werkstoffe und verfahren zur modulierung der p66 expression - Google Patents
Werkstoffe und verfahren zur modulierung der p66 expressionInfo
- Publication number
- DE60020348D1 DE60020348D1 DE60020348T DE60020348T DE60020348D1 DE 60020348 D1 DE60020348 D1 DE 60020348D1 DE 60020348 T DE60020348 T DE 60020348T DE 60020348 T DE60020348 T DE 60020348T DE 60020348 D1 DE60020348 D1 DE 60020348D1
- Authority
- DE
- Germany
- Prior art keywords
- shc
- serine
- expression
- vitro
- vivo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000338 in vitro Methods 0.000 abstract 2
- 238000001727 in vivo Methods 0.000 abstract 2
- 230000004792 oxidative damage Effects 0.000 abstract 2
- 238000006366 phosphorylation reaction Methods 0.000 abstract 2
- 101150018665 MAPK3 gene Proteins 0.000 abstract 1
- 241000699670 Mus sp. Species 0.000 abstract 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
- 238000002679 ablation Methods 0.000 abstract 1
- 230000002950 deficient Effects 0.000 abstract 1
- 230000006801 homologous recombination Effects 0.000 abstract 1
- 238000002744 homologous recombination Methods 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 230000003938 response to stress Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Emergency Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9906515 | 1999-03-22 | ||
| GBGB9906515.3A GB9906515D0 (en) | 1999-03-22 | 1999-03-22 | Materials and methods relating to the effects oF P66 expression |
| PCT/GB2000/001079 WO2000056886A1 (en) | 1999-03-22 | 2000-03-22 | MATERIALS AND METHODS RELATING TO MODULATION OF p66 EXPRESSION |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60020348D1 true DE60020348D1 (de) | 2005-06-30 |
| DE60020348T2 DE60020348T2 (de) | 2006-02-02 |
Family
ID=10850083
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60020348T Expired - Fee Related DE60020348T2 (de) | 1999-03-22 | 2000-03-22 | Werkstoffe und verfahren zur modulierung der p66 expression |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1163335B1 (de) |
| JP (1) | JP2002539789A (de) |
| AT (1) | ATE296352T1 (de) |
| AU (1) | AU778301B2 (de) |
| CA (1) | CA2367464A1 (de) |
| DE (1) | DE60020348T2 (de) |
| DK (1) | DK1163335T3 (de) |
| ES (1) | ES2243237T3 (de) |
| GB (1) | GB9906515D0 (de) |
| WO (1) | WO2000056886A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1654377A4 (de) | 2002-03-01 | 2010-03-24 | Roger Williams Hospital | MIT DEM Shc-PROTEIN VERBUNDENE VERFAHREN UND ZUSAMMENSETZUNGEN ZUR PROGNOSE VON BRUST-, PROSTATA- UND EIERSTOCKKREBS |
| GB0722759D0 (en) * | 2007-11-20 | 2008-01-02 | Congenia S R L | Antisense oligonucleotides for the modulation of gene expression and methods relating to the use thereof |
| US20140179774A1 (en) * | 2012-12-26 | 2014-06-26 | Industrial Technology Research Institute | Methods for inhibition of shc-1/p66 to combat aging-related diseases |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5744313A (en) * | 1994-12-09 | 1998-04-28 | The Regents Of The University Of California | Assay employing novel protein domain which binds tyrosine phosphorylated proteins |
-
1999
- 1999-03-22 GB GBGB9906515.3A patent/GB9906515D0/en not_active Ceased
-
2000
- 2000-03-22 DE DE60020348T patent/DE60020348T2/de not_active Expired - Fee Related
- 2000-03-22 CA CA002367464A patent/CA2367464A1/en not_active Abandoned
- 2000-03-22 WO PCT/GB2000/001079 patent/WO2000056886A1/en not_active Ceased
- 2000-03-22 DK DK00911131T patent/DK1163335T3/da active
- 2000-03-22 AT AT00911131T patent/ATE296352T1/de not_active IP Right Cessation
- 2000-03-22 EP EP00911131A patent/EP1163335B1/de not_active Expired - Lifetime
- 2000-03-22 ES ES00911131T patent/ES2243237T3/es not_active Expired - Lifetime
- 2000-03-22 JP JP2000606745A patent/JP2002539789A/ja active Pending
- 2000-03-22 AU AU33124/00A patent/AU778301B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DK1163335T3 (da) | 2005-09-19 |
| CA2367464A1 (en) | 2000-09-28 |
| AU3312400A (en) | 2000-10-09 |
| EP1163335B1 (de) | 2005-05-25 |
| ES2243237T3 (es) | 2005-12-01 |
| WO2000056886A1 (en) | 2000-09-28 |
| GB9906515D0 (en) | 1999-05-19 |
| JP2002539789A (ja) | 2002-11-26 |
| EP1163335A1 (de) | 2001-12-19 |
| DE60020348T2 (de) | 2006-02-02 |
| ATE296352T1 (de) | 2005-06-15 |
| AU778301B2 (en) | 2004-11-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: CONGENIA S.R.L., MILANO, IT |
|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |