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DE60015390D1 - Antidiabetische thiazolidindione und ihre herstellung - Google Patents

Antidiabetische thiazolidindione und ihre herstellung

Info

Publication number
DE60015390D1
DE60015390D1 DE60015390T DE60015390T DE60015390D1 DE 60015390 D1 DE60015390 D1 DE 60015390D1 DE 60015390 T DE60015390 T DE 60015390T DE 60015390 T DE60015390 T DE 60015390T DE 60015390 D1 DE60015390 D1 DE 60015390D1
Authority
DE
Germany
Prior art keywords
antidiabetic
indions
thiazolide
production
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60015390T
Other languages
English (en)
Other versions
DE60015390T2 (de
DE60015390T9 (de
Inventor
Janos Fischer
Tamas Fodor
Sandor Levai
Ildiko Ballo
Endrene Petenyi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of DE60015390D1 publication Critical patent/DE60015390D1/de
Publication of DE60015390T2 publication Critical patent/DE60015390T2/de
Application granted granted Critical
Publication of DE60015390T9 publication Critical patent/DE60015390T9/de
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Processing Of Stones Or Stones Resemblance Materials (AREA)
DE60015390T 1999-12-18 2000-12-14 Antidiabetische thiazolidindione und ihre herstellung Active DE60015390T9 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU9904634 1999-12-18
HU9904634A HU225919B1 (en) 1999-12-18 1999-12-18 Thiazolidine-derivatives, process for their preparation pharmaceutical and intermediates
PCT/HU2000/000129 WO2001044240A1 (en) 1999-12-18 2000-12-14 Antidiabetic thiazolidinediones and their preparation

Publications (3)

Publication Number Publication Date
DE60015390D1 true DE60015390D1 (de) 2004-12-02
DE60015390T2 DE60015390T2 (de) 2005-10-13
DE60015390T9 DE60015390T9 (de) 2006-01-26

Family

ID=90000182

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60015390T Active DE60015390T9 (de) 1999-12-18 2000-12-14 Antidiabetische thiazolidindione und ihre herstellung

Country Status (6)

Country Link
EP (2) EP1242418B1 (de)
AT (1) ATE280767T1 (de)
AU (1) AU2210401A (de)
DE (1) DE60015390T9 (de)
HU (1) HU225919B1 (de)
WO (1) WO2001044240A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0006133D0 (en) 2000-03-14 2000-05-03 Smithkline Beecham Plc Novel pharmaceutical
JP4573978B2 (ja) 2000-09-19 2010-11-04 キヤノン株式会社 画像形成装置
GB0023970D0 (en) * 2000-09-29 2000-11-15 Smithkline Beecham Plc Novel pharmaceutical
GB0023971D0 (en) * 2000-09-29 2000-11-15 Smithkline Beecham Plc Novel pharmaceutical
WO2002051823A1 (en) * 2000-12-26 2002-07-04 Torrent Pharmaceuticals Ltd Process for the preparation of rosiglitazone maleate
GB0129872D0 (en) * 2001-12-13 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
WO2003050112A1 (en) * 2001-12-13 2003-06-19 Smithkline Beecham Plc Toluenesulfonate hydrates of a thiazolidinedione derivative
GB0129851D0 (en) * 2001-12-13 2002-01-30 Smithkline Beecham Plc Novel compounds
GB0129876D0 (en) * 2001-12-13 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
AR047541A1 (es) * 2004-02-13 2006-01-25 Sandoz Ag Fosfato de 5-[[4-[2-metil-2-piridinil-amino-etoxi]fenil]metil]-2,4 tiazolidinadiona (rosiglitazona) y sus formas polimorficas
GB2413795A (en) * 2004-05-05 2005-11-09 Cipla Ltd Process for the preparation of rosiglitazone
EP1745043A1 (de) * 2004-05-12 2007-01-24 Medichem S.A. Verfahren zur herstellung von rosiglitazon
CZ298424B6 (cs) * 2005-05-24 2007-09-26 Zentiva, A. S. Zpusob krystalizace rosiglitazonu a jeho derivátuze smesných rozpouštedel
HUP0600517A3 (en) * 2006-06-23 2008-10-28 Richter Gedeon Nyrt Process for the production of benzylidene-rosiglitazone base
HUP0800755A2 (en) 2008-12-11 2010-09-28 Richter Gedeon Nyrt Crystalline forms of rosiglitazone
DE102009053562A1 (de) 2009-11-18 2011-05-19 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Rosiglitazonsuccinat enthaltende pharmazeutische Zusammensetzung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3856378T2 (de) * 1987-09-04 2000-05-11 Beecham Group P.L.C., Brentford Substituierte Thiazolidindionderivate
GB9124513D0 (en) * 1991-11-19 1992-01-08 Smithkline Beecham Plc Novel process
GB9308487D0 (en) * 1993-04-23 1993-06-09 Smithkline Beecham Plc Novel compounds
GB9723295D0 (en) * 1997-11-04 1998-01-07 Smithkline Beecham Plc Novel process
CN1183130C (zh) * 1999-09-24 2005-01-05 中国人民解放军军事医学科学院毒物药物研究所 噻唑烷类衍生物及其医药用途
GB0023970D0 (en) * 2000-09-29 2000-11-15 Smithkline Beecham Plc Novel pharmaceutical

Also Published As

Publication number Publication date
DE60015390T2 (de) 2005-10-13
EP1242418B1 (de) 2004-10-27
WO2001044240A1 (en) 2001-06-21
HUP9904634A2 (hu) 2002-01-28
HU9904634D0 (en) 2000-02-28
HU225919B1 (en) 2007-12-28
ATE280767T1 (de) 2004-11-15
EP1242418A1 (de) 2002-09-25
EP1475378A1 (de) 2004-11-10
AU2210401A (en) 2001-06-25
DE60015390T9 (de) 2006-01-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition