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DE60015563D1 - Verfahren zur herstellung von benzoperhydroisoindolen - Google Patents

Verfahren zur herstellung von benzoperhydroisoindolen

Info

Publication number
DE60015563D1
DE60015563D1 DE60015563T DE60015563T DE60015563D1 DE 60015563 D1 DE60015563 D1 DE 60015563D1 DE 60015563 T DE60015563 T DE 60015563T DE 60015563 T DE60015563 T DE 60015563T DE 60015563 D1 DE60015563 D1 DE 60015563D1
Authority
DE
Germany
Prior art keywords
benzoperhydroisoindols
producing
benzoperhydroisindole
compounds
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60015563T
Other languages
English (en)
Other versions
DE60015563T2 (de
Inventor
Patrick Mailliet
Christophe Salagnad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Application granted granted Critical
Publication of DE60015563D1 publication Critical patent/DE60015563D1/de
Publication of DE60015563T2 publication Critical patent/DE60015563T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/62—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60015563T 1999-07-22 2000-07-20 Verfahren zur herstellung von benzoperhydroisoindolen Expired - Fee Related DE60015563T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9909508 1999-07-22
FR9909508A FR2796641B1 (fr) 1999-07-22 1999-07-22 Nouveau procede de preparation de composes benzoperhydroisoindole
PCT/FR2000/002082 WO2001007408A2 (fr) 1999-07-22 2000-07-20 Nouveau procede de preparation de composes benzoperhydroisoindole

Publications (2)

Publication Number Publication Date
DE60015563D1 true DE60015563D1 (de) 2004-12-09
DE60015563T2 DE60015563T2 (de) 2005-12-22

Family

ID=9548392

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60015563T Expired - Fee Related DE60015563T2 (de) 1999-07-22 2000-07-20 Verfahren zur herstellung von benzoperhydroisoindolen

Country Status (14)

Country Link
US (1) US6291679B1 (de)
EP (1) EP1206452B1 (de)
JP (1) JP2003505448A (de)
AT (1) ATE281434T1 (de)
AU (1) AU6578400A (de)
CA (1) CA2379859A1 (de)
DE (1) DE60015563T2 (de)
DK (1) DK1206452T3 (de)
ES (1) ES2230139T3 (de)
FR (1) FR2796641B1 (de)
IL (1) IL146811A0 (de)
PT (1) PT1206452E (de)
SI (1) SI1206452T1 (de)
WO (1) WO2001007408A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7569689B2 (en) * 2004-01-16 2009-08-04 Bristol-Myers Squibb Company Modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
US7253283B2 (en) 2004-01-16 2007-08-07 Bristol-Myers Squibb Company Tricyclic modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
US7326728B2 (en) * 2004-01-16 2008-02-05 Bristol-Myers Squibb Company Modulators of glucocorticoid receptor, AP-1, and/or NF-κβ activity and use thereof
US7605264B2 (en) * 2004-01-16 2009-10-20 Bristol-Myers Squibb Company Heterocyclic modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
US7273881B2 (en) * 2004-01-16 2007-09-25 Bristol-Myers Squibb Company Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
US7625921B2 (en) * 2004-01-16 2009-12-01 Bristol-Myers Squibb Company Modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
US7361654B2 (en) 2005-01-13 2008-04-22 Bristol-Myers Squibb Co. Substituted heteroaryl amide modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
US7642273B2 (en) * 2005-01-13 2010-01-05 Bristol-Myers Squibb Company Modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
US7411071B2 (en) * 2005-01-13 2008-08-12 Bristol-Myers Squibb Company Modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
US7317024B2 (en) 2005-01-13 2008-01-08 Bristol-Myers Squibb Co. Heterocyclic modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3922752A1 (de) * 1989-07-11 1991-01-17 Boehringer Ingelheim Kg Verfahren zur herstellung von r-(+) -3-oxocycloalkancarbonsaeureniederalkylestern
NZ275691A (en) 1993-11-05 1998-03-25 Warner Lambert Co Di and tripeptides and compositions thereof which inhibit farnesyl transferase
FR2736641B1 (fr) 1995-07-10 1997-08-22 Rhone Poulenc Rorer Sa Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2757855B1 (fr) * 1996-12-30 1999-01-29 Rhone Poulenc Rorer Sa Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
US6013662A (en) * 1996-12-30 2000-01-11 Rhone-Poulenc Rorer S.A. Farnesyl transferase inhibitors, their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments
US6124465A (en) * 1997-11-25 2000-09-26 Rhone-Poulenc S.A. Farnesyl transferase inhibitors, their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments
JP2001527078A (ja) * 1997-12-23 2001-12-25 アベンテイス・フアルマ・ソシエテ・アノニム 新規なファルネシルトランスフェラーゼインヒビター、それらの製造、それらを含有する製薬学的組成物及び医薬品の製造のためのそれらの使用
FR2772764B1 (fr) 1997-12-23 2000-01-14 Rhone Poulenc Rorer Sa Nouveaux inhibiteurs de farnesyle transferase, leur preparation, les compositions pharmaceutiques qui les contiennent et leur utilisation pour la preparation de medicaments

Also Published As

Publication number Publication date
DK1206452T3 (da) 2005-03-14
IL146811A0 (en) 2002-07-25
SI1206452T1 (en) 2005-04-30
CA2379859A1 (fr) 2001-02-01
PT1206452E (pt) 2005-02-28
ATE281434T1 (de) 2004-11-15
WO2001007408A3 (fr) 2001-05-17
DE60015563T2 (de) 2005-12-22
WO2001007408A2 (fr) 2001-02-01
US6291679B1 (en) 2001-09-18
ES2230139T3 (es) 2005-05-01
FR2796641A1 (fr) 2001-01-26
JP2003505448A (ja) 2003-02-12
EP1206452A2 (de) 2002-05-22
EP1206452B1 (de) 2004-11-03
FR2796641B1 (fr) 2001-09-21
AU6578400A (en) 2001-02-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8339 Ceased/non-payment of the annual fee