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DE60012196D1 - Herstellungsverfahren für derivate der naphthyridin-3-carbonsäure - Google Patents

Herstellungsverfahren für derivate der naphthyridin-3-carbonsäure

Info

Publication number
DE60012196D1
DE60012196D1 DE60012196T DE60012196T DE60012196D1 DE 60012196 D1 DE60012196 D1 DE 60012196D1 DE 60012196 T DE60012196 T DE 60012196T DE 60012196 T DE60012196 T DE 60012196T DE 60012196 D1 DE60012196 D1 DE 60012196D1
Authority
DE
Germany
Prior art keywords
naphthyridin
derivatives
production process
carbonic acid
carbonic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60012196T
Other languages
English (en)
Other versions
DE60012196T2 (de
Inventor
Sungwook Cho
Hoon Choi
John David Hayler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LG Chem Ltd
Original Assignee
LG Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LG Life Sciences Ltd filed Critical LG Life Sciences Ltd
Publication of DE60012196D1 publication Critical patent/DE60012196D1/de
Application granted granted Critical
Publication of DE60012196T2 publication Critical patent/DE60012196T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE60012196T 1999-09-03 2000-09-01 Verfahren zur Herstellung von Naphthyridin-3-carbonsäurederivaten Expired - Lifetime DE60012196T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9920917 1999-09-03
GBGB9920917.3A GB9920917D0 (en) 1999-09-03 1999-09-03 Novel process
PCT/GB2000/003366 WO2001018002A1 (en) 1999-09-03 2000-09-01 Process for production of naphthyridine-3-carboxylic acid derivatives

Publications (2)

Publication Number Publication Date
DE60012196D1 true DE60012196D1 (de) 2004-08-19
DE60012196T2 DE60012196T2 (de) 2005-08-18

Family

ID=10860353

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60012196T Expired - Lifetime DE60012196T2 (de) 1999-09-03 2000-09-01 Verfahren zur Herstellung von Naphthyridin-3-carbonsäurederivaten

Country Status (23)

Country Link
US (1) US7232907B2 (de)
EP (1) EP1214321B1 (de)
JP (1) JP4208464B2 (de)
KR (1) KR100724311B1 (de)
CN (1) CN1275963C (de)
AR (1) AR029002A1 (de)
AT (1) ATE271050T1 (de)
AU (1) AU773722B2 (de)
BR (1) BRPI0013751B8 (de)
CA (1) CA2383753C (de)
CO (1) CO5470281A1 (de)
DE (1) DE60012196T2 (de)
DK (1) DK1214321T3 (de)
ES (1) ES2223574T3 (de)
GB (1) GB9920917D0 (de)
HK (1) HK1047093B (de)
MX (1) MXPA02002355A (de)
MY (1) MY125309A (de)
PT (1) PT1214321E (de)
SI (1) SI1214321T1 (de)
TW (1) TWI274753B (de)
WO (1) WO2001018002A1 (de)
ZA (1) ZA200201781B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2281817C (en) * 1999-06-29 2008-07-29 Smithkline Beecham Corporation Methods of use of fluoroquinolone compounds against maxillary sinus pathogenic bacteria
GB9920919D0 (en) 1999-09-03 1999-11-10 Sb Pharmco Inc Novel compound
GB9920917D0 (en) 1999-09-03 1999-11-10 Sb Pharmco Inc Novel process
PT1412078E (pt) 2001-08-02 2009-01-08 Lg Life Sciences Ltd Processos para a produção de derivados amino-protegidos da 4- aminometileno-pirrolidin-3-ona, gemifloxacina ou um seu sal
KR100517638B1 (ko) * 2002-04-08 2005-09-28 주식회사 엘지생명과학 게미플록사신 산염의 새로운 제조방법
KR100653334B1 (ko) * 2003-03-07 2006-12-04 주식회사 엘지생명과학 4-아미노메틸-3-알콕시이미노피롤리딘 메탄설폰산염의 신규한 제조 방법
WO2006134431A1 (en) * 2005-05-03 2006-12-21 Ranbaxy Laboratories Limited Formate salt of gemifloxacin
EP2161270A1 (de) 2005-06-15 2010-03-10 Hetero Drugs Limited Gemifloxacinhydrate
WO2008053324A1 (en) * 2006-10-31 2008-05-08 Orchid Chemicals & Pharmaceuticals Limited An improved process for the preparation of gemifloxacin mesylate

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57134482A (en) 1981-02-13 1982-08-19 Dainippon Pharmaceut Co Ltd 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8- naphthyridine-3-carboxylic acid-3/2 hydrate and its preparation
IN162769B (de) 1984-11-13 1988-07-09 Kyorin Seiyaku Kk
NZ222047A (en) 1986-10-08 1991-01-29 Bristol Myers Co Quinoline - or naphthyridine - carboxylic acid anti-bacterial agents
JPH01100165A (ja) 1987-10-13 1989-04-18 Shionogi & Co Ltd オキシムまたはヒドロキシアミン誘導体系抗菌剤
US4920120A (en) 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
JPH0356479A (ja) 1989-07-24 1991-03-12 Takeshi Yokota 水溶性キノロン誘導体のｐ‐トルエンスルホン酸塩
IE66202B1 (en) 1989-08-16 1995-12-13 Pfizer Azabicyclo quinolone carboxylic acids
US5137892A (en) 1990-12-12 1992-08-11 Abbott Laboratories Quinoline, naphthyridine and pyridobenzoxazine derivatives
EP0541086A1 (de) 1991-11-08 1993-05-12 Kaken Pharmaceutical Co., Ltd. Antibakterielle 6-Fluoro-Chinolone mit einer Oximegruppe an dem Substituent in Position 7
JPH0673056A (ja) 1992-08-26 1994-03-15 Kaken Pharmaceut Co Ltd キノリンカルボン酸誘導体およびその塩
US5776944A (en) 1994-06-16 1998-07-07 Lg Chemical Ltd. 7-(4-aminomethyl-3-methyloxyiminopyrroplidin-1-yl)-1-cyclopropyl-6-flu oro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid and the process for the preparation thereof
DE69509442T2 (de) * 1994-06-16 1999-09-02 Lg Chemical Ltd. Chinolincarbonsäurederivate mit 7-(4-Amino-methyl-3-oxim)-pyrrolidin-Substituenten und Verfahren zu ihrer Herstellung
JP3449658B2 (ja) 1994-12-21 2003-09-22 杏林製薬株式会社 安定性に優れた８−アルコキシキノロンカルボン酸水和物並びにその製造方法
JP3145715B2 (ja) 1995-06-06 2001-03-12 ファイザー・インコーポレーテッド 無水７−（［１α，５α，６α］−６−アミノ−３−アザビシクロ［３．１．０］ヘキサ−３−イル）−６−フルオロ−１−（２，４−ジフルオロフェニル）−１，４−ジヒドロ−４−オキソ−１，８−ナフチリディン−３−カルボン酸メタンスルホン酸塩の新規な結晶形態
HUP9802862A3 (en) 1995-08-11 1999-05-28 Pfizer (1s,2s)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanolmethanesulfonate trihydrate and pharmaceutical compositions containing it for treating cns disorders
SK282346B6 (sk) 1996-03-29 2002-01-07 Smithkline Beecham Corporation Dihydrát monometánsulfonátu kyseliny (E)-alfa-[2-n-butyl-1-[(4- karboxyfenyl)metyl]-1H-imidazol-5-yl]metylén-2- tiofénpropiónovej, spôsob jeho prípravy, farmaceutický prostriedok s jeho obsahom
MA24500A1 (fr) * 1997-03-21 1998-10-01 Lg Life Sciences Ltd Derive du sel d'acide carboxylique de naphthyridine .
KR100286874B1 (ko) 1998-03-04 2001-04-16 성재갑 보호된 4-아미노메틸-피롤리딘-3-온의 제조방법
ATE249432T1 (de) 1998-05-29 2003-09-15 Upjohn Co 3-((1'-n-methylamino)ethyl-n-benzyl)pyrrolidin- monomethanesulfonat
GB9820405D0 (en) 1998-09-18 1998-11-11 Smithkline Beecham Plc Process
ES2299430T3 (es) 1999-06-29 2008-06-01 Lg Life Sciences, Ltd. Utilizacion de compuestos de gemifloxacina contra bacterias.
EP1401440A4 (de) 1999-09-01 2006-07-05 Lg Life Sciences Ltd Verfahren zur verwendung von fluorchinolone verbindungen gegen bakterien
GB9920917D0 (en) 1999-09-03 1999-11-10 Sb Pharmco Inc Novel process
GB9920919D0 (en) 1999-09-03 1999-11-10 Sb Pharmco Inc Novel compound
EP1561465A3 (de) 1999-09-22 2005-12-21 LG Life Sciences, Ltd. Verfahren zur Verwendung von fluorochinolonen Verbindungen gegen Bakterien
KR20010091379A (ko) 2000-03-15 2001-10-23 성재갑 7-(4-아미노메틸-3-옥심)피롤리딘 치환체를 갖는 퀴놀린카르복실산 유도체의 신규 제조방법
KR20020018560A (ko) 2000-09-01 2002-03-08 성재갑 3-아미노메틸-4-ｚ-메톡시이미노피롤리딘의 신규 제조방법

Also Published As

Publication number Publication date
US7232907B2 (en) 2007-06-19
WO2001018002A1 (en) 2001-03-15
EP1214321A1 (de) 2002-06-19
PT1214321E (pt) 2004-10-29
BR0013751A (pt) 2002-05-07
CA2383753C (en) 2011-06-28
HK1047093A1 (en) 2003-02-07
CA2383753A1 (en) 2001-03-15
CN1275963C (zh) 2006-09-20
HK1047093B (en) 2005-05-27
ZA200201781B (en) 2003-06-25
EP1214321B1 (de) 2004-07-14
KR100724311B1 (ko) 2007-06-04
GB9920917D0 (en) 1999-11-10
ATE271050T1 (de) 2004-07-15
AU773722B2 (en) 2004-06-03
BR0013751B1 (pt) 2013-02-05
TWI274753B (en) 2007-03-01
AU7019700A (en) 2001-04-10
CN1377350A (zh) 2002-10-30
JP4208464B2 (ja) 2009-01-14
MXPA02002355A (es) 2004-07-16
BRPI0013751B8 (pt) 2021-05-25
ES2223574T3 (es) 2005-03-01
SI1214321T1 (en) 2004-12-31
JP2003508532A (ja) 2003-03-04
AR029002A1 (es) 2003-06-04
MY125309A (en) 2006-07-31
DK1214321T3 (da) 2004-10-25
DE60012196T2 (de) 2005-08-18
KR20020041421A (ko) 2002-06-01
US20050176961A1 (en) 2005-08-11
CO5470281A1 (es) 2004-12-30

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