DE60008374D1 - Anästhetische zubereitung enthaltend einen nmda-antagonisten und einen alpha-2 adrenergen agonisten - Google Patents
Anästhetische zubereitung enthaltend einen nmda-antagonisten und einen alpha-2 adrenergen agonistenInfo
- Publication number
- DE60008374D1 DE60008374D1 DE60008374T DE60008374T DE60008374D1 DE 60008374 D1 DE60008374 D1 DE 60008374D1 DE 60008374 T DE60008374 T DE 60008374T DE 60008374 T DE60008374 T DE 60008374T DE 60008374 D1 DE60008374 D1 DE 60008374D1
- Authority
- DE
- Germany
- Prior art keywords
- alpha
- nmda antagonist
- agonist
- adrenergen
- preparation containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003703 n methyl dextro aspartic acid receptor blocking agent Substances 0.000 title abstract 3
- 230000003444 anaesthetic effect Effects 0.000 title abstract 2
- 239000000556 agonist Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- 239000000384 adrenergic alpha-2 receptor agonist Substances 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Anesthesiology (AREA)
- Inorganic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9913677.2A GB9913677D0 (en) | 1999-06-11 | 1999-06-11 | Formulation |
| GB9913677 | 1999-06-11 | ||
| PCT/GB2000/002271 WO2000076545A1 (en) | 1999-06-11 | 2000-06-09 | Anaesthetic formulation comprising an nmda-antagonist and an alpha-2 adrenergic agonist |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60008374D1 true DE60008374D1 (de) | 2004-03-25 |
| DE60008374T2 DE60008374T2 (de) | 2004-12-09 |
Family
ID=10855216
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60008374T Expired - Lifetime DE60008374T2 (de) | 1999-06-11 | 2000-06-09 | Anästhetische zubereitung enthaltend einen nmda-antagonisten und einen alpha-2 adrenergen agonisten |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6562855B1 (de) |
| EP (1) | EP1187635B1 (de) |
| JP (1) | JP2003529541A (de) |
| AT (1) | ATE259658T1 (de) |
| AU (1) | AU778671B2 (de) |
| CA (1) | CA2376916C (de) |
| DE (1) | DE60008374T2 (de) |
| DK (1) | DK1187635T3 (de) |
| ES (1) | ES2215678T3 (de) |
| GB (2) | GB9913677D0 (de) |
| PT (1) | PT1187635E (de) |
| RU (1) | RU2244558C2 (de) |
| WO (1) | WO2000076545A1 (de) |
| ZA (1) | ZA200110116B (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2812545B1 (fr) * | 2000-08-03 | 2003-03-28 | Air Liquide Sante Int | Aerosol medicamenteux inhalable dans le traitement ou la prevention de la douceur |
| GB0209998D0 (en) * | 2002-05-01 | 2002-06-12 | Protexeon Ltd | Use |
| ES2321185T3 (es) | 2002-06-12 | 2009-06-03 | Air Liquide Deutschland Gmbh | Proteccion cerebral con un gas que contiene xenon. |
| US20050255169A1 (en) * | 2002-07-05 | 2005-11-17 | Messer Griesheim | Adjuvant containing xenon |
| WO2004052337A2 (de) * | 2002-12-06 | 2004-06-24 | Michael Georgieff | Nasale pharmazeutische präparation enthaltend eine lipophile flüssige oder gasförmige wirksubstanz |
| CA2542412A1 (en) * | 2003-10-21 | 2005-05-06 | Aga Ab | Use of xenon for the prevention of programmed cell death |
| US7795263B2 (en) * | 2008-07-08 | 2010-09-14 | Wildlife Laboratories, Inc. | Pharmaceutical combination for and method of anesthetizing and immobilizing non-domesticated mammals |
| US20100022574A1 (en) * | 2008-07-28 | 2010-01-28 | EndogenX, Inc. | Methods to Treat Pain Using an Alpha-2 Adrenergic Agonist and an Endothelin Antagonist |
| US20110244058A1 (en) * | 2008-08-01 | 2011-10-06 | Gerald Horn | Compositions and methods for treatment of pulmonary diseases and conditions |
| US12246013B2 (en) | 2008-08-01 | 2025-03-11 | Eye Therapies Llc | Vasoconstriction compositions and methods of use |
| US8952011B2 (en) | 2008-08-01 | 2015-02-10 | Eye Therapies Llc | Compositions and methods for the treatment of nasal conditions |
| US8338421B2 (en) | 2008-08-01 | 2012-12-25 | Alpha Synergy Development, Inc. | Compositions and methods for reversing rebound hyperemia |
| US20100203165A1 (en) | 2008-08-01 | 2010-08-12 | Gerald Horn | Compositions and methods for treatment of disorders or conditions of the eye |
| KR101859486B1 (ko) * | 2009-05-15 | 2018-06-28 | 레크로파마, 인코포레이티드 | 설하용 덱스메데토미딘 조성물과 그의 사용 방법 |
| US8987270B2 (en) | 2009-07-27 | 2015-03-24 | Eye Therapies Llc | Formulations of selective alpha-2 agonists and methods of use thereof |
| US20110152271A1 (en) * | 2009-12-17 | 2011-06-23 | Gerald Horn | Compositions and methods for ophthalmic delivery of nasal decongestants |
| AU2011204315A1 (en) * | 2010-01-08 | 2012-08-02 | Recro Pharma, Inc. | Topical transdermal dexmedetomidine compositions and methods of use thereof |
| CN103068394A (zh) * | 2010-04-15 | 2013-04-24 | 皇家学习促进学会/麦吉尔大学 | 对于疼痛的局部治疗 |
| US8445526B2 (en) | 2011-02-03 | 2013-05-21 | Glaucoma & Nasal Therapies Llc | Compositions and methods for treatment of glaucoma |
| US20130096170A1 (en) | 2011-10-14 | 2013-04-18 | Hospira, Inc. | Methods of treating pediatric patients using dexmedetomidine |
| SG11201403094TA (en) | 2011-12-11 | 2014-10-30 | Recro Pharma Inc | Intranasal dexmedetomidine compositions and methods of use thereof |
| CN103565745A (zh) | 2012-08-10 | 2014-02-12 | 德克萨斯州大学系统董事会 | 用于治疗中风的神经保护性脂质体组合物和方法 |
| AU2014233018A1 (en) | 2013-03-15 | 2015-10-01 | The Board Of Regents Of The University Of Texas System | Liquids rich in noble gas and methods of their preparation and use |
| US8999938B2 (en) | 2013-06-21 | 2015-04-07 | Gnt Llc | Ophthalmic lipophilic drug delivery vehicle formulations |
| KR101831290B1 (ko) | 2013-10-07 | 2018-02-22 | 테이코쿠 팔마 유에스에이, 인코포레이티드 | 덱스메데토미딘 경피 조성물을 사용하여 주의력 결핍 과잉행동 장애, 불안 및 불면증을 치료하기 위한 방법 및 조성물 |
| RU2646512C2 (ru) | 2013-10-07 | 2018-03-05 | ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. | Устройства для трансдермальной доставки дексмедетомидина и способы их применения |
| RU2648449C2 (ru) | 2013-10-07 | 2018-03-26 | ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. | Способы и композиции для трансдермальной доставки неседативного количества дексмедетомидина |
| RU2557882C1 (ru) * | 2014-07-08 | 2015-07-27 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Астраханская государственная медицинская академия" Министерства здравоохранения Российской Федерации (ГБОУ ВПО АГМА Минздрава России) | Способ проведения премедикации при плановом хирургическом лечении |
| WO2017139382A1 (en) * | 2016-02-08 | 2017-08-17 | The Texas A&M University System | Combination of adjuvant drugs esketamine and brimonidine for medical treatments |
| RU2723761C1 (ru) | 2016-10-31 | 2020-06-17 | ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. | Способы устранения боли с использованием устройств для трансдермальной доставки дексмедетомидина |
| WO2023287726A1 (en) | 2021-07-12 | 2023-01-19 | Penland Foundation | Treatment of cancer using botulinum toxin and nitrous oxide |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4859685A (en) * | 1986-08-13 | 1989-08-22 | Boc, Inc. | Anesthetic composition and method of using the same |
| US5605911A (en) * | 1995-01-31 | 1997-02-25 | Washington University | Use of alpha-2 adrenergic drugs to prevent adverse effects of NMDA receptor hypofunction (NRH) |
| US6083720A (en) | 1995-11-13 | 2000-07-04 | Chroboczek; Jadwiga | Dodecahedral adenoviral protein complex, composition containing same and uses thereof |
| DE19709704C2 (de) | 1997-03-10 | 1999-11-04 | Michael Georgieff | Verwendung einer flüssigen Präparation von Xenon zur intravenösen Verabreichung bei Einleitung und/oder Aufrechterhaltung der Anaesthesie |
| FR2787713A1 (fr) | 1998-12-23 | 2000-06-30 | Johan Huysman | Composition en tant que medicament et utilisation d'une telle composition pour l'obtention d'un medicament destine a l'anesthesie, notamment medicament analgesique |
| DE19910986C2 (de) | 1999-03-11 | 2001-06-07 | Aga Ab | Verwendung von Xenon bei der Behandlung von Neurointoxikationen |
| GB9917822D0 (en) * | 1999-07-29 | 1999-09-29 | Imperial College | Nmda antagonist |
-
1999
- 1999-06-11 GB GBGB9913677.2A patent/GB9913677D0/en not_active Ceased
-
2000
- 2000-06-09 WO PCT/GB2000/002271 patent/WO2000076545A1/en not_active Ceased
- 2000-06-09 AT AT00940519T patent/ATE259658T1/de active
- 2000-06-09 DK DK00940519T patent/DK1187635T3/da active
- 2000-06-09 DE DE60008374T patent/DE60008374T2/de not_active Expired - Lifetime
- 2000-06-09 PT PT00940519T patent/PT1187635E/pt unknown
- 2000-06-09 ES ES00940519T patent/ES2215678T3/es not_active Expired - Lifetime
- 2000-06-09 AU AU55444/00A patent/AU778671B2/en not_active Ceased
- 2000-06-09 US US10/018,007 patent/US6562855B1/en not_active Expired - Lifetime
- 2000-06-09 RU RU2002100254/15A patent/RU2244558C2/ru not_active IP Right Cessation
- 2000-06-09 EP EP00940519A patent/EP1187635B1/de not_active Expired - Lifetime
- 2000-06-09 JP JP2001502877A patent/JP2003529541A/ja not_active Ceased
- 2000-06-09 GB GB0014165A patent/GB2352633B/en not_active Expired - Fee Related
- 2000-06-09 CA CA2376916A patent/CA2376916C/en not_active Expired - Lifetime
-
2001
- 2001-12-10 ZA ZA200110116A patent/ZA200110116B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2376916C (en) | 2010-09-21 |
| GB2352633B (en) | 2002-04-17 |
| AU778671B2 (en) | 2004-12-16 |
| AU5544400A (en) | 2001-01-02 |
| JP2003529541A (ja) | 2003-10-07 |
| GB9913677D0 (en) | 1999-08-11 |
| PT1187635E (pt) | 2004-07-30 |
| GB2352633A (en) | 2001-02-07 |
| ES2215678T3 (es) | 2004-10-16 |
| DK1187635T3 (da) | 2004-06-21 |
| GB0014165D0 (en) | 2000-08-02 |
| ATE259658T1 (de) | 2004-03-15 |
| EP1187635A1 (de) | 2002-03-20 |
| RU2244558C2 (ru) | 2005-01-20 |
| US6562855B1 (en) | 2003-05-13 |
| EP1187635B1 (de) | 2004-02-18 |
| DE60008374T2 (de) | 2004-12-09 |
| CA2376916A1 (en) | 2000-12-21 |
| ZA200110116B (en) | 2003-07-23 |
| WO2000076545A1 (en) | 2000-12-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8363 | Opposition against the patent | ||
| 8365 | Fully valid after opposition proceedings |