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DE60008584D1 - Benzamidin-derivate - Google Patents

Benzamidin-derivate

Info

Publication number
DE60008584D1
DE60008584D1 DE60008584T DE60008584T DE60008584D1 DE 60008584 D1 DE60008584 D1 DE 60008584D1 DE 60008584 T DE60008584 T DE 60008584T DE 60008584 T DE60008584 T DE 60008584T DE 60008584 D1 DE60008584 D1 DE 60008584D1
Authority
DE
Germany
Prior art keywords
blood
coagulation
inhibiting
benzamidine derivatives
effect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60008584T
Other languages
English (en)
Other versions
DE60008584T2 (de
Inventor
Kaoru Yoshida
Tadakiyo Nakagawa
Takashi Kayahara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Publication of DE60008584D1 publication Critical patent/DE60008584D1/de
Application granted granted Critical
Publication of DE60008584T2 publication Critical patent/DE60008584T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/59—Hydrogenated pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60008584T 1999-12-08 2000-12-07 Benzamidin-derivate Expired - Lifetime DE60008584T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP34850499 1999-12-08
JP34850499 1999-12-08
PCT/JP2000/008656 WO2001042254A1 (en) 1999-12-08 2000-12-07 Benzamidine derivatives

Publications (2)

Publication Number Publication Date
DE60008584D1 true DE60008584D1 (de) 2004-04-01
DE60008584T2 DE60008584T2 (de) 2004-11-04

Family

ID=18397469

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60008584T Expired - Lifetime DE60008584T2 (de) 1999-12-08 2000-12-07 Benzamidin-derivate

Country Status (7)

Country Link
US (1) US6784191B2 (de)
EP (1) EP1236735B1 (de)
JP (1) JP4446145B2 (de)
AT (1) ATE260102T1 (de)
AU (1) AU1733101A (de)
DE (1) DE60008584T2 (de)
WO (1) WO2001042254A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1847527A4 (de) * 2005-02-02 2009-04-08 Ajinomoto Kk Neue benzamidinverbindungen
KR102059120B1 (ko) * 2011-07-05 2019-12-24 백톤 디킨슨 앤드 컴퍼니 응고 조절제 및 그를 포함하는 장치
CN103933488A (zh) * 2013-01-17 2014-07-23 赵明义 用于治疗脑血栓的配方

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5952307A (en) * 1994-01-21 1999-09-14 Georgia Tech Research Corp. Basic α-aminoalkylphosphonate derivatives
JPH11140040A (ja) * 1997-11-06 1999-05-25 Kissei Pharmaceut Co Ltd ３−アミジノフェニルエーテル誘導体、活性化血液凝固第ｘ因子阻害剤およびそれらの製造中間体
EP0992994B1 (de) 1997-12-12 2008-03-12 Sony Corporation Optische platte aufzeichnungs/wiedergabeverfahren, optische platte und optischeplattenvorrichtung
CA2334476A1 (en) * 1998-06-08 1999-12-16 Ajinomoto Co., Inc. Benzamidine derivative
EP1236712B1 (de) * 1999-12-06 2008-08-06 Ajinomoto Co., Inc. Amidinophenylbrenztraubensäure-derivat

Also Published As

Publication number Publication date
AU1733101A (en) 2001-06-18
US20020193348A1 (en) 2002-12-19
EP1236735B1 (de) 2004-02-25
ATE260102T1 (de) 2004-03-15
DE60008584T2 (de) 2004-11-04
EP1236735A1 (de) 2002-09-04
WO2001042254A1 (en) 2001-06-14
JP4446145B2 (ja) 2010-04-07
EP1236735A4 (de) 2002-10-29
US6784191B2 (en) 2004-08-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition