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DE60003194D1 - Sedativ hypnotische zusammensetzungen mit gesteuerter freisetzung und diesbezügliche verfahren - Google Patents

Sedativ hypnotische zusammensetzungen mit gesteuerter freisetzung und diesbezügliche verfahren

Info

Publication number
DE60003194D1
DE60003194D1 DE60003194T DE60003194T DE60003194D1 DE 60003194 D1 DE60003194 D1 DE 60003194D1 DE 60003194 T DE60003194 T DE 60003194T DE 60003194 T DE60003194 T DE 60003194T DE 60003194 D1 DE60003194 D1 DE 60003194D1
Authority
DE
Germany
Prior art keywords
sedative
compound
hypnotic
controlled release
related procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60003194T
Other languages
English (en)
Other versions
DE60003194T2 (de
Inventor
D Bruce Campbell
Jay Thiele
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neurocrine Biosciences Inc
Original Assignee
Neurocrine Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurocrine Biosciences Inc filed Critical Neurocrine Biosciences Inc
Application granted granted Critical
Publication of DE60003194D1 publication Critical patent/DE60003194D1/de
Publication of DE60003194T2 publication Critical patent/DE60003194T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE60003194T 1999-08-26 2000-08-28 Sedativ hypnotische zusammensetzungen mit gesteuerter freisetzung und diesbezügliche verfahren Expired - Fee Related DE60003194T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38444899A 1999-08-26 1999-08-26
US384448 1999-08-26
PCT/US2000/023665 WO2001013895A2 (en) 1999-08-26 2000-08-28 Controlled-release sedative-hypnotic compositions and methods related thereto

Publications (2)

Publication Number Publication Date
DE60003194D1 true DE60003194D1 (de) 2003-07-10
DE60003194T2 DE60003194T2 (de) 2004-06-17

Family

ID=23517364

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60003194T Expired - Fee Related DE60003194T2 (de) 1999-08-26 2000-08-28 Sedativ hypnotische zusammensetzungen mit gesteuerter freisetzung und diesbezügliche verfahren

Country Status (9)

Country Link
EP (2) EP1206248B1 (de)
JP (1) JP2003507413A (de)
AT (1) ATE241968T1 (de)
AU (1) AU7335500A (de)
DE (1) DE60003194T2 (de)
DK (1) DK1206248T3 (de)
ES (1) ES2199857T3 (de)
PT (1) PT1206248E (de)
WO (1) WO2001013895A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050038042A1 (en) * 2002-11-15 2005-02-17 Jenet Codd Modified release composition comprising a short-acting hypnotic for treatment of sleep disorders
CA2538064C (en) * 2003-09-15 2013-12-17 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
GB0423964D0 (en) * 2004-10-28 2004-12-01 Jagotec Ag Dosage form
US20070020333A1 (en) * 2005-07-20 2007-01-25 Chin-Chih Chiang Controlled release of hypnotic agents
EP1970056A1 (de) * 2007-03-15 2008-09-17 Polichem S.A. Zeitspezifische Dosierformen mit verzögerter/pulsatiler Freisetzung
JP5749247B2 (ja) 2010-02-22 2015-07-15 第一三共株式会社 経口用徐放性固形製剤
EP2540294B1 (de) * 2010-02-22 2016-08-03 Daiichi Sankyo Company, Limited Feststoffpräparat mit verzögerter freisetzung zur oralen verabreichung
CN102670613A (zh) * 2011-03-16 2012-09-19 中国人民解放军军事医学科学院毒物药物研究所 用于改善茚地普隆溶出的药物组合物及其制备方法
JP6129184B2 (ja) 2012-09-03 2017-05-17 第一三共株式会社 ヒドロモルフォン塩酸塩含有の経口用徐放性医薬組成物
PT3102189T (pt) * 2014-02-06 2019-12-11 Bo Chen Lan Composição e método para melhorar o sono

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4654347A (en) * 1983-06-23 1987-03-31 American Cyanamid Company Aryl and heteroaryl[[7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]methanones
US4948592A (en) * 1986-05-09 1990-08-14 Alza Corporation Pulsed drug delivery
HRP970493A2 (en) * 1996-09-23 1998-08-31 Wienman E. Phlips Oral delayed immediate release medical formulation and method for preparing the same
EP1064937A1 (de) * 1999-06-28 2001-01-03 Sanofi-Synthelabo Pharmazeutische Zusammensetzungen mit kontrollierten Freigabe enthaltend ein Hypnotikum mit kurzer Wirkung oder deren Salze
US6472528B1 (en) * 1999-08-10 2002-10-29 Neurocrine Biosciences, Inc. Synthesis of substituted pyrazolopyrimidines

Also Published As

Publication number Publication date
WO2001013895A3 (en) 2001-09-27
DE60003194T2 (de) 2004-06-17
EP1206248A2 (de) 2002-05-22
EP1206248B1 (de) 2003-06-04
PT1206248E (pt) 2003-11-28
ATE241968T1 (de) 2003-06-15
EP1352647A1 (de) 2003-10-15
JP2003507413A (ja) 2003-02-25
WO2001013895A2 (en) 2001-03-01
AU7335500A (en) 2001-03-19
ES2199857T3 (es) 2004-03-01
DK1206248T3 (da) 2003-09-29

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee