DE60001748D1 - Verfahren zur synthese von beta-laktamderivaten - Google Patents
Verfahren zur synthese von beta-laktamderivatenInfo
- Publication number
- DE60001748D1 DE60001748D1 DE60001748T DE60001748T DE60001748D1 DE 60001748 D1 DE60001748 D1 DE 60001748D1 DE 60001748 T DE60001748 T DE 60001748T DE 60001748 T DE60001748 T DE 60001748T DE 60001748 D1 DE60001748 D1 DE 60001748D1
- Authority
- DE
- Germany
- Prior art keywords
- synthesising
- lactam derivatives
- beta lactam
- carbamoylation
- cefuroxime
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title abstract 4
- 150000003952 β-lactams Chemical class 0.000 title 1
- 230000021235 carbamoylation Effects 0.000 abstract 2
- JFPVXVDWJQMJEE-IZRZKJBUSA-N cefuroxime Chemical compound N([C@@H]1C(N2C(=C(COC(N)=O)CS[C@@H]21)C(O)=O)=O)C(=O)\C(=N/OC)C1=CC=CO1 JFPVXVDWJQMJEE-IZRZKJBUSA-N 0.000 abstract 2
- 229960001668 cefuroxime Drugs 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999MI001655A IT1313569B1 (it) | 1999-07-27 | 1999-07-27 | Processo per la sintesi di derivati beta-lattamici. |
| PCT/EP2000/007068 WO2001007443A1 (en) | 1999-07-27 | 2000-07-24 | A process for the synthesis of beta-lactam derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60001748D1 true DE60001748D1 (de) | 2003-04-24 |
| DE60001748T2 DE60001748T2 (de) | 2003-10-16 |
Family
ID=11383419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60001748T Expired - Fee Related DE60001748T2 (de) | 1999-07-27 | 2000-07-24 | Verfahren zur synthese von beta-laktamderivaten |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6642378B1 (de) |
| EP (1) | EP1196420B1 (de) |
| KR (1) | KR20020031391A (de) |
| CN (1) | CN1364169A (de) |
| AT (1) | ATE234845T1 (de) |
| AU (1) | AU5986700A (de) |
| CA (1) | CA2380183A1 (de) |
| DE (1) | DE60001748T2 (de) |
| DK (1) | DK1196420T3 (de) |
| ES (1) | ES2193973T3 (de) |
| IT (1) | IT1313569B1 (de) |
| PT (1) | PT1196420E (de) |
| TR (1) | TR200200196T2 (de) |
| WO (1) | WO2001007443A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT411996B (de) | 2000-09-11 | 2004-08-26 | Sandoz Ag | Verfahren zur herstellung von cefuroxim in der form seines n-butylammoniumsalzes |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3966717A (en) * | 1971-05-14 | 1976-06-29 | Glaxo Laboratories Limited | 7-β-Acylamido-3-carbamoyloxymethylceph-3-em-4-carboxylic acids and salts thereof |
| BE875371A (fr) * | 1978-04-07 | 1979-10-08 | Glaxo Group Ltd | Procede de preparation de 3-carbamoyloxymethyl-cephalosporines et nouvelles cephalosporines |
| GB2018764B (en) * | 1978-04-07 | 1982-09-02 | Glaxo Group Ltd | Cephalosporin compounds |
| GB8810394D0 (en) * | 1988-05-03 | 1988-06-08 | Glaxo Group Ltd | Chemical process |
| DE4321842A1 (de) * | 1993-07-01 | 1995-01-12 | Basf Ag | Verfahren zur Herstellung von alpha, omega-Dicarbonsäurediestern |
-
1999
- 1999-07-27 IT IT1999MI001655A patent/IT1313569B1/it active
-
2000
- 2000-07-24 DE DE60001748T patent/DE60001748T2/de not_active Expired - Fee Related
- 2000-07-24 WO PCT/EP2000/007068 patent/WO2001007443A1/en not_active Ceased
- 2000-07-24 EP EP00945949A patent/EP1196420B1/de not_active Expired - Lifetime
- 2000-07-24 TR TR2002/00196T patent/TR200200196T2/xx unknown
- 2000-07-24 ES ES00945949T patent/ES2193973T3/es not_active Expired - Lifetime
- 2000-07-24 AT AT00945949T patent/ATE234845T1/de not_active IP Right Cessation
- 2000-07-24 CA CA002380183A patent/CA2380183A1/en not_active Abandoned
- 2000-07-24 DK DK00945949T patent/DK1196420T3/da active
- 2000-07-24 CN CN00810821.8A patent/CN1364169A/zh active Pending
- 2000-07-24 KR KR1020027001009A patent/KR20020031391A/ko not_active Withdrawn
- 2000-07-24 PT PT00945949T patent/PT1196420E/pt unknown
- 2000-07-24 AU AU59867/00A patent/AU5986700A/en not_active Abandoned
- 2000-07-24 US US10/031,990 patent/US6642378B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IT1313569B1 (it) | 2002-09-09 |
| DK1196420T3 (da) | 2003-07-14 |
| CA2380183A1 (en) | 2001-02-01 |
| ITMI991655A0 (it) | 1999-07-27 |
| ES2193973T3 (es) | 2003-11-16 |
| KR20020031391A (ko) | 2002-05-01 |
| DE60001748T2 (de) | 2003-10-16 |
| AU5986700A (en) | 2001-02-13 |
| EP1196420B1 (de) | 2003-03-19 |
| CN1364169A (zh) | 2002-08-14 |
| ITMI991655A1 (it) | 2001-01-27 |
| EP1196420A1 (de) | 2002-04-17 |
| TR200200196T2 (tr) | 2002-07-22 |
| ATE234845T1 (de) | 2003-04-15 |
| US6642378B1 (en) | 2003-11-04 |
| PT1196420E (pt) | 2003-06-30 |
| WO2001007443A1 (en) | 2001-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |