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DE502005000428D1 - Process for the preparation of 1,2-diaminocyclohexane-platinum (II) complexes - Google Patents

Process for the preparation of 1,2-diaminocyclohexane-platinum (II) complexes

Info

Publication number
DE502005000428D1
DE502005000428D1 DE502005000428T DE502005000428T DE502005000428D1 DE 502005000428 D1 DE502005000428 D1 DE 502005000428D1 DE 502005000428 T DE502005000428 T DE 502005000428T DE 502005000428 T DE502005000428 T DE 502005000428T DE 502005000428 D1 DE502005000428 D1 DE 502005000428D1
Authority
DE
Germany
Prior art keywords
diaminocyclohexane
complexes
platinum
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE502005000428T
Other languages
German (de)
Inventor
Andreas Dr Pepels
Ralf-Dieter Dr Schnebeck
Holger Dr Rauter
Friedrich Dr Wissmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Heraeus Deutschland GmbH and Co KG
Original Assignee
WC Heraus GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by WC Heraus GmbH and Co KG filed Critical WC Heraus GmbH and Co KG
Publication of DE502005000428D1 publication Critical patent/DE502005000428D1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE502005000428T 2004-02-05 2005-01-15 Process for the preparation of 1,2-diaminocyclohexane-platinum (II) complexes Expired - Lifetime DE502005000428D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004005906A DE102004005906B3 (en) 2004-02-05 2004-02-05 Process for the preparation of 1,2-diaminocylohexane-platinum (II) complexes

Publications (1)

Publication Number Publication Date
DE502005000428D1 true DE502005000428D1 (en) 2007-04-19

Family

ID=34673186

Family Applications (2)

Application Number Title Priority Date Filing Date
DE102004005906A Expired - Fee Related DE102004005906B3 (en) 2004-02-05 2004-02-05 Process for the preparation of 1,2-diaminocylohexane-platinum (II) complexes
DE502005000428T Expired - Lifetime DE502005000428D1 (en) 2004-02-05 2005-01-15 Process for the preparation of 1,2-diaminocyclohexane-platinum (II) complexes

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE102004005906A Expired - Fee Related DE102004005906B3 (en) 2004-02-05 2004-02-05 Process for the preparation of 1,2-diaminocylohexane-platinum (II) complexes

Country Status (17)

Country Link
US (1) US7309796B2 (en)
EP (1) EP1561754B1 (en)
JP (1) JP3997232B2 (en)
CN (2) CN1680411A (en)
AR (1) AR047519A1 (en)
AT (1) ATE356136T1 (en)
AU (1) AU2005200417C1 (en)
BR (1) BRPI0500307A (en)
CA (1) CA2492254C (en)
CY (1) CY1106579T1 (en)
DE (2) DE102004005906B3 (en)
DK (1) DK1561754T3 (en)
ES (1) ES2281031T3 (en)
MX (1) MXPA05001428A (en)
PL (1) PL1561754T3 (en)
PT (1) PT1561754E (en)
SI (1) SI1561754T1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005051966A1 (en) 2003-11-25 2005-06-09 Platco Technologies (Proprietary) Limited Platinum(ii) complexes, preparation and use
TW200617014A (en) * 2004-07-12 2006-06-01 Sicor Inc Cis-diiodo-(trans-l-1,2-cyclohexanediamine) platinum (Ⅱ) complex and processes for preparing high purity oxaliplatin
WO2006024897A1 (en) 2004-09-01 2006-03-09 Platco Technologies (Proprietary) Limited Preparation of platinum(ii) complexes
US8068647B2 (en) 2005-06-14 2011-11-29 General Electric Company Method and apparatus for real-time motion correction for ultrasound spatial compound imaging
CA2640621A1 (en) * 2006-01-30 2007-08-02 Platco Technologies (Proprietary) Limited Preparation of platinum (ii) complexes
US20090076139A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched oxalplatin
AR072238A1 (en) * 2009-01-13 2010-08-18 Eriochem Sa PROCESS TO PREPARE NEUTRAL ANATYNOPLASIC DERIVATIVES OF PLATINUM (II) PHARMACEUTICAL DEGREE WITH LOW SILVER CONTENT
EP2208731B1 (en) 2009-06-26 2012-08-15 Umicore AG & Co. KG Process for preparation of 1,2-diamino-cyclohexane-platinum(II) complexes
CN101891771B (en) * 2010-07-30 2012-12-12 重庆泰濠制药有限公司 Method for preparing oxaliplatin
CN103232494A (en) * 2012-05-22 2013-08-07 湖北一半天制药有限公司 Oxaliplatin preparation method
JP7180923B2 (en) 2018-09-01 2022-11-30 ベイジン ショウバイ ファーマシューティカル カンパニー，リミティッド Platinum-based compound phosphate and method for producing the same
CN111569868A (en) * 2020-06-10 2020-08-25 上海济平新能源科技有限公司 Method for preparing catalyst loaded on carbon

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6041077B2 (en) * 1976-09-06 1985-09-13 喜徳 喜谷 Cis platinum(2) complex of 1,2-diaminocyclohexane isomer
US4206208A (en) * 1977-08-29 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Use of 4-carboxy-phthalato(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof with cyclophosphamide and 5-fluorouracil in alleviating L1210 murine leukemia
US4206226A (en) 1977-08-29 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Use of 4-carboxy-phthalato-(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof in alleviating L1210 murine leukemia
GR75598B (en) * 1980-04-29 1984-08-01 Sanofi Sa
US4665210A (en) * 1984-12-17 1987-05-12 American Cyanamid Company Platinum complexes of aliphatic tricarboxylic acids
ATE49214T1 (en) 1984-12-17 1990-01-15 American Cyanamid Co PLATINUM COMPLEXES OF ALIPHATIC TRICARBONIC ACIDS.
EP0376076A1 (en) * 1988-12-27 1990-07-04 Ss Pharmaceutical Co., Ltd. Novel platinum complex
JPH0776230B2 (en) * 1992-01-13 1995-08-16 田中貴金属工業株式会社 Method for producing platinum compound
JP2673331B2 (en) * 1993-01-12 1997-11-05 田中貴金属工業 株式会社 Optically pure cis-oxalate (trans-1-1,2-cyclohexanediamine) platinum (▲ II ▼)
JPH06287021A (en) * 1992-04-22 1994-10-11 Tanaka Kikinzoku Kogyo Kk Optical resolution method for optically active platinum complex compounds
JP3025602B2 (en) * 1993-05-21 2000-03-27 デビオファーム エス．アー． Method for producing optically high purity cis-oxalate (trans-l-l, 2-cyclohexanediamine) platinum (II) complex
US20040186172A1 (en) * 2001-07-02 2004-09-23 Houssam Ibrahim Oxaliplatin active substance with a very low content of oxalic acid
DE10226592B4 (en) * 2002-06-14 2004-07-29 Faustus Forschungs Cie. Translational Cancer Research Gmbh Anti-tumor platinum (II) oxalato complexes
TW200617014A (en) * 2004-07-12 2006-06-01 Sicor Inc Cis-diiodo-(trans-l-1,2-cyclohexanediamine) platinum (Ⅱ) complex and processes for preparing high purity oxaliplatin

Also Published As

Publication number Publication date
BRPI0500307A (en) 2005-11-08
ES2281031T3 (en) 2007-09-16
AU2005200417A1 (en) 2005-08-25
DK1561754T3 (en) 2007-06-11
AU2005200417B2 (en) 2007-07-12
CA2492254A1 (en) 2005-08-05
PL1561754T3 (en) 2007-07-31
AU2005200417C1 (en) 2008-04-03
EP1561754B1 (en) 2007-03-07
JP2005220138A (en) 2005-08-18
EP1561754A1 (en) 2005-08-10
MXPA05001428A (en) 2005-09-30
SI1561754T1 (en) 2007-08-31
AR047519A1 (en) 2006-01-25
CY1106579T1 (en) 2012-01-25
US20050197389A1 (en) 2005-09-08
CN103214525A (en) 2013-07-24
US7309796B2 (en) 2007-12-18
ATE356136T1 (en) 2007-03-15
PT1561754E (en) 2007-04-30
JP3997232B2 (en) 2007-10-24
AU2005200417B8 (en) 2005-08-25
CA2492254C (en) 2010-03-16
CN1680411A (en) 2005-10-12
DE102004005906B3 (en) 2005-09-29

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