DE4320117A1 - Combination products - Google Patents
Combination productsInfo
- Publication number
- DE4320117A1 DE4320117A1 DE19934320117 DE4320117A DE4320117A1 DE 4320117 A1 DE4320117 A1 DE 4320117A1 DE 19934320117 DE19934320117 DE 19934320117 DE 4320117 A DE4320117 A DE 4320117A DE 4320117 A1 DE4320117 A1 DE 4320117A1
- Authority
- DE
- Germany
- Prior art keywords
- metabolites
- indications
- main
- still
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000002207 metabolite Substances 0.000 claims description 8
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 4
- 239000000470 constituent Substances 0.000 claims description 3
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims description 2
- 235000004866 D-panthenol Nutrition 0.000 claims description 2
- 239000011703 D-panthenol Substances 0.000 claims description 2
- 229930003427 Vitamin E Natural products 0.000 claims description 2
- 229960003949 dexpanthenol Drugs 0.000 claims description 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 2
- 208000019423 liver disease Diseases 0.000 claims description 2
- 230000000926 neurological effect Effects 0.000 claims description 2
- 239000000126 substance Substances 0.000 claims description 2
- 235000019156 vitamin B Nutrition 0.000 claims description 2
- 239000011720 vitamin B Substances 0.000 claims description 2
- 235000019165 vitamin E Nutrition 0.000 claims description 2
- 229940046009 vitamin E Drugs 0.000 claims description 2
- 239000011709 vitamin E Substances 0.000 claims description 2
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 claims 2
- AGBQKNBQESQNJD-SSDOTTSWSA-N (R)-lipoic acid Chemical compound OC(=O)CCCC[C@@H]1CCSS1 AGBQKNBQESQNJD-SSDOTTSWSA-N 0.000 claims 1
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 claims 1
- AGBQKNBQESQNJD-UHFFFAOYSA-N alpha-Lipoic acid Natural products OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 claims 1
- 235000019136 lipoic acid Nutrition 0.000 claims 1
- 229940055726 pantothenic acid Drugs 0.000 claims 1
- 235000019161 pantothenic acid Nutrition 0.000 claims 1
- 239000011713 pantothenic acid Substances 0.000 claims 1
- 229960002663 thioctic acid Drugs 0.000 claims 1
- 239000002253 acid Substances 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Description
Die Kombinationspräparate bestehen zumindest aus α-Lipon säure und oder ihrer Abkömmlinge und oder ihrer Bestand teile und oder ihrer Metabolite und Pantethensäure (bzw. Dexpanthenol) und oder ihrer Abkömmlinge und oder ihrer Bestandteile und oder ihrer Metabolite.The combination preparations consist at least of α-lipon acid and or its descendants and or its stock parts and or their metabolites and pantethenic acid (or Dexpanthenol) and or their descendants and or their Ingredients and or their metabolites.
Sie sind insbesondere zur Behandlung von den verschiedens ten neurologischen Indikationen (s. Hauptanmeldung) und Hautindikationen (s. Zusatzanmeldung (P 43 13 428.9) usw. geeignet. Sie sollen aber auch für jede weitere Indikation, die eventuell noch möglich ist, abgedeckt sein.They are especially used to treat the various neurological indications (see main registration) and Skin indications (see additional registration (P 43 13 428.9) etc. suitable. But they should also be used for any other indication, that may still be possible.
Die Kombinationspräparate gemäß den Ansprüchen in der Haupt- und in den Zusatzanmeldungen können auch oder an Stelle der B-Vitamine deren Abkömmlinge, deren Bestandteile oder deren Metabolite enthalten. Auch alle Abkömmlinge von Vitamin E, dessen Bestandteile und oder dessen Metabolite können darin vorkommen. Auch andere Substanzen können darin vorkommen.The combination preparations according to the claims in the main and in the additional applications can also or instead of B vitamins their descendants, their components or their Metabolites included. Also all descendants of vitamin E, its constituents and or its metabolites can therein occurrence. Other substances can also be found in it.
Sämtliche Ansprüche in der Haupt- und in den Zusatzanmel dungen sollen für Lebererkrankungen und für jede weitere Indikation, die eventuell noch möglich ist, abgedeckt sein und natürlich für die bereits genannten Indikationen un abhängig davon, was man noch dazu mixt.All claims in the main and additional applications are intended for liver diseases and for every further Indication that may still be possible and of course for the indications already mentioned depending on what you mix.
Claims (4)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19924201196 DE4201196C2 (en) | 1992-01-18 | 1992-01-18 | Medicines used to treat polyneuropathy |
| DE19934320117 DE4320117A1 (en) | 1992-01-18 | 1993-06-18 | Combination products |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19924201196 DE4201196C2 (en) | 1992-01-18 | 1992-01-18 | Medicines used to treat polyneuropathy |
| DE19934320117 DE4320117A1 (en) | 1992-01-18 | 1993-06-18 | Combination products |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE4320117A1 true DE4320117A1 (en) | 1994-12-22 |
Family
ID=25911055
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19934320117 Withdrawn DE4320117A1 (en) | 1992-01-18 | 1993-06-18 | Combination products |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE4320117A1 (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3802895A1 (en) * | 1988-02-01 | 1989-08-10 | Koeltringer Peter | Combination product for the treatment of disorders and injuries of nerve cells and nerve fibres |
| DE4035456A1 (en) * | 1989-11-09 | 1991-05-16 | Asta Pharma Ag | Pharmaceutical composition |
| DE9200543U1 (en) * | 1992-01-18 | 1992-05-07 | Rabien, Margarethe, 65239 Hochheim | Ataxia medication in which a-lipoic acid + pantothenic acid or dexpanthenol are combined (also against MS, muscular atrophy, polyneuropathy, etc.) |
| DE4201196A1 (en) * | 1992-01-18 | 1993-08-12 | Rabien Margarethe | Use of multi component compsn. contg. alpha lipoic acid and vitamin(s) |
| DE4218572A1 (en) * | 1992-06-05 | 1993-12-09 | Asta Medica Ag | Synergistic combination of drugs containing as active ingredient alpha-lipoic acid, dihydrolipoic acid, their metabolites as well as the oxidized and reduced enantiomers of alpha-lipoic acid such as R-alpha-lipoic acid or S-alpha-lipoic acid and metabolites of alpha-lipoic acid with vitamins A, B1 -6, B12, C and E |
-
1993
- 1993-06-18 DE DE19934320117 patent/DE4320117A1/en not_active Withdrawn
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3802895A1 (en) * | 1988-02-01 | 1989-08-10 | Koeltringer Peter | Combination product for the treatment of disorders and injuries of nerve cells and nerve fibres |
| DE4035456A1 (en) * | 1989-11-09 | 1991-05-16 | Asta Pharma Ag | Pharmaceutical composition |
| DE9200543U1 (en) * | 1992-01-18 | 1992-05-07 | Rabien, Margarethe, 65239 Hochheim | Ataxia medication in which a-lipoic acid + pantothenic acid or dexpanthenol are combined (also against MS, muscular atrophy, polyneuropathy, etc.) |
| DE4201196A1 (en) * | 1992-01-18 | 1993-08-12 | Rabien Margarethe | Use of multi component compsn. contg. alpha lipoic acid and vitamin(s) |
| DE4218572A1 (en) * | 1992-06-05 | 1993-12-09 | Asta Medica Ag | Synergistic combination of drugs containing as active ingredient alpha-lipoic acid, dihydrolipoic acid, their metabolites as well as the oxidized and reduced enantiomers of alpha-lipoic acid such as R-alpha-lipoic acid or S-alpha-lipoic acid and metabolites of alpha-lipoic acid with vitamins A, B1 -6, B12, C and E |
Non-Patent Citations (6)
| Title |
|---|
| Chemical-Abstracts: Vol.109,1988,Ref.209980h * |
| Derwent-Abstracts, Ref.87-255392/36 * |
| Vol. 79,1973,Ref.135593x * |
| Vol. 83,1975,Ref. 523m * |
| Vol. 90,1979,Ref.166927r * |
| Vol.108,1988,Ref.220675n * |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AF | Is addition to no. |
Ref country code: DE Ref document number: 4201196 Format of ref document f/p: P |
|
| OM8 | Search report available as to paragraph 43 lit. 1 sentence 1 patent law | ||
| AF | Is addition to no. |
Ref country code: DE Ref document number: 4201196 Format of ref document f/p: P |
|
| 8141 | Disposal/no request for examination |