DE4020874A1 - Soft drink giving protection against sun-light exposure - contains carotenoid and Vitamin=C or Vitamin=E - Google Patents

Abstract

In an anti-sun protective compsn. on a liq. base, with a carotenoid mixt., alone or in admixture with vitamin C and/or E and/or other physiologically acceptable antioxidants, the content of these substances is not more than 10 RDA vitamin A equivs. of provitamin A-active carotenoids/l of liq. (RDA = max. recommended daily dose). USE/ADVANTAGE - The compsn. is a soft drink on a nutrient basis, which gives protection against damage by exposure to UV light, esp. against skin cancer. The systemic absorption of carotenoids and other anti-sun protectants can be adjusted according to the exposure to sunlight, without excessive dosing. The greater the exposure to the sun, the greater the thirst, and the greater the amt. of the drink taken.

Description

The present invention relates to a soft drink beverage Food base containing carotenoids, which as Protection against damage caused by UV light exposure, esp special skin cancer in humans, is usable.

It has long been known that UV light is a major cause for skin cancer is. The prior art uses numerous protective agents against the dangers of UV light exposure, especially protective materials that apply topically to the skin such as sun ointments and lotions nen that contain light protection materials, be it on Water, alcohol or oil based. This approach - so far the only effective course of action has prevailed and was accepted - has the Notable disadvantage that they have a large amount of Sunscreen materials are required, some of which recently suspected under these conditions toxic and harmful to health in various ways be. Furthermore, it is difficult to maintain a constant and maintain even skin coverage with protective ointments and the effectiveness of such protective means protecting the skin from UVA radiation is also questionable.

It has been known for some time that systemic Carotenoids and antioxidants both with and without Provitamin A activity as a protective agent against Sun exposure risks are effective.

Recently it has been suggested carotenoid intake through dietary measures or oral use of  Carotenoid administration, e.g. Gelatin capsules and / or tablets to increase. However, this approach is not optimal, because the appetite from sun and heat exposure is reduced and because of the intake of antioxidants in concentrated form, e.g. by swallowing tablets, which should preferably be taken with meals, lead to uneven doses of antioxidants, those with metabolic interactions and also with toxicity can be related.

Such systemic approaches also have the Noteworthy disadvantage that they are not with the actual sun exposure are synchronized and therefore unnecessarily large - or ineffectively small - quantities Protective agents can be found in the system.

It is therefore an object of the present invention to provide a vehicle to make available through which the systemic Auf ingestion of carotenoids and other light stabilizers in a way that is related to sun exposure can be turned without the amount needed to achieve reliable physiological protection Exposure to solar radiation is essential, too exceed and / or without the recommended by Daily maximum dose (RDA) generally accepted To breach security restrictions.

This task is solved by the characteristics of the contractor Proverbs 1 and 8.

It is an advantage of the present invention Food drink available for sun exposure too put which carotenoids as the basic ones Contains sunscreen, which is at least one disadvantage the methods of the prior art are overcome and which has comparatively high levels of light stabilizers  and provides antioxidants in the body when they are most needed because they are fast on the one hand be recorded and on the other hand their concentration in the System decreases at high speed so that a systemic protective effect is provided.

Therefore, the invention is directed to a soft drink beverage the one carotenoid mixture, alone or together with Vitamin C and / or Vitamin E and / or other antioxidants in an amount containing 10 vitamin A RDA equivalents Provitamin A carotenoids per liter of cold drink, not exceeds. Intake of carotenoids and related Sunscreen is a function of sun and Heat exposure. The more a person is exposed to the sun is, the greater the amount of carotenoid that it will take up because of thirst and drinking in the Ratio, which corresponds to the extent / degree of Exposure to sun and heat corresponds.

It should be understood that the addition of vitamins C and E or selenium to the carotenoid-containing drink has a synergistic effect insofar as reduced gluta thion (GSH) and vitamin E in the prevention of peroxidation of nuclear material are involved and vitamin C through its regenerating effect on vitamin E also in this Wise works. As a result, these additives can be used in protection contribute to the initial phase of skin damage, whereas Ca rotinoids tend to be in the later release stages of the photoreak tion are effective.

Other additives that can be used include antioxidants and Factors directly or indirectly related to radical scavengers for example GSH or Se and / or CoQ10 related stand. These can be in the form of individual substances as natural occurring components of vegetable or fruit juices and / or plant preparations are added.  

Typically, a mixture of carotenoids contains a number of Carotenoids, such as, for example, β-carotene, canthaxanthin, Zeaxanthin, Lycopen, Lutein, Crocetin, Capsanthin or Like. The RDA equivalents of such a mixture are based on due to the relative provitamin A activity of those Calculated carotenoids which have provitamin A activity, provided that all of these carotenoids have Provitamin A activity can be converted into vitamin A, e.g. B. β: 100%, α: 50-54%, Γ: 42-50%, β-zeacarotin: 20-40%, cryptoxane thin: 50-60%, β-apo-8-carotinal: 72%, β-apo-12-carotinal: 120%, etc.

Among the various advantages of the invention is also said to be be emphasized that a drink is an excellent vehicle for the purposes of the present invention because it it is generally accepted and proven that drinking at warm weather is beneficial. Furthermore, thirst can pass through the addition of sugars or equivalent substances in high Proportions are stimulated to encourage further drinking. The Will to drink the mixture of the invention naturally better stimulated with tasty drinks.

If the beverage according to the invention as an application method is used, the risk of an overdose is minimized because overdosing can occur if too large Amount of substance is absorbed by the body is not used because the body does not use it so much needed, like when sun exposure in one Way takes place that the body is caused that Take up sunscreen. This problem is solved with the proportional substance absorption by the invention Drink resolved on its own.

It has also been found that vitamin C carotenoids protects and therefore allows the addition of vitamin C.  lower carotenoid concentrations to work what is of course desirable. Furthermore, there exists a synergism between vitamin C and vitamin E, as Vitamin E (tocopherol) from the tocopheryl radical Vitamin C is regenerated.

Vitamin C can also be in other forms or precursors are made available which are metabolized to get vitamin C, such as Ascorbyl palmitate. One found of the ascorbyl palmitate itself out that it is more effective compared to ascorbic acid Protect carotene and internal organs, e.g. B. liver free radicals. Maybe that's because it is is more easily soluble in adipose tissue.

While the limits of provitamin A and carotenoids Vitamins that should be taken daily, self-consumption are the current RDAs, are some examples of increased concentrations and other compositions, which are to be used according to the invention, subsequently described in detail herein.

It is, of course, believed that the following Examples are for the purpose of illustration only and none have a restricting effect. Different flavors and Additives, which are then reproduced in more detail that are also only given more precisely by way of example and one skilled in the art is capable of other relevant Addi tive, flavorings or the like. Available so that created a drink in the sense of the invention becomes.

Among the many additives that can be used herbal tonics are used as possible suitable additives closed, e.g. Cucumber herb, aloe vera, peppermint, soda nen / lemons, ginseng, barley tea (barley water), anise, pam  pelmuses, raspberries, strawberries, hawthorn berries, rosemary, Watercress, Guarana, Papavera rhoea, Achilea milfolia, Arcitium lappaa, Chrysanthemum, Parthenium, Cola vera, Elentherococcus, Bingo bilboa, Japanese Apricot (UMA) etc.

The following composition examples illustrate some of the many uses of the invention. While some bei games of active substance levels hereinafter thereafter are specified, the skilled worker is aware of this be that many different combinations of Carotenoids and other active ingredients Can be made available depending on the Final composition requirements in terms of aroma, Color, RDA etc.

In general, the addition of active substances, for example by following the general instructions given below happen.

Liquids soluble in milk / fat

Fat emulsion-carotenoid mixture: β-carotene 30% suspension: 8 mg (for light drinks, e.g. Pina Colada) up to 25 mg (Butter raspberry), 60 mg (cocoa), per liter cocoa / raspberry Buttermilk preparations. Apocarotinal (yellow-orange-brown Color), 30% fat emulsion base: 5-15 mg / l for cocoa and other coffee-based liquids and ice types. Canthaxanthin 1% water soluble: 500-2000 mg / l in strawberry and cocoa preparations. αTocopherol (e.g. Hoffmann-La Roche): 0-400 mg / l drink.

Water-based drinks

Carotenoid mixture, such as canthaxanthin powder (water soluble) 10% and β-carotene powder 1%. Dark drinks  like raspberry, strawberry or cola contain (per liter) that following: 350-2500 mg β-carotene 1% and 500-1500 mg Canthaxanthin 10%. Apo-carotene, 30% fat emulsifier base, 1: 1 mixed with emulsifier for ginger lemonade: 5-15 mg / l.

For lightly colored beverages mostly β-carotene, e.g. 350 mg / l for lime / lemon drinks and 700-2500 mg / l for Mint drinks.

Vitamin C: Water-soluble mixture: L-ascorbic acid or As corbate, depending on taste needs between 50-2000 mg / l. As corbyl palmitate mixture (water-insoluble): ratio 1: 1 or ascorbyl palmitate and emulsifier: Application range: 200-8000 mg Mix per liter of drink.

example 1 Instant tangerine orange powder

A powder is prepared, which is dissolved in water (130 g / l), adding the following ingredients: 82.73% cane sugar / white sugar, 10% flavorings (like e.g. HNR mandarin orange flavor 48230), 3% Citric acid, 3% dextrose, 1% clouding agent (e.g. HNR). Buffer: 0.5% trisodium citrate, 0.5% Tricalcium phosphate. 0.2% ascorbic acid, 0.07% Food coloring.

Diet version: Due to a sweetness index of cane sugar = 1, one part of sugar is made up of 1/200 part of aspartame or 1/250 Part acesulfame-K replaced.

To the above, 1-5 RDA equivalents of β-carotene and α-To copherol in a water emulsion base and L-ascorbic acid (Hoffmann-La Roche) or ascorbyl palmitate (ICN Biochemicals) added.  

Example 2 Orange drink

An orange drink can be made, the following Ingredients contain: 150 g juice (10.5.BX) or 24.6 oran gene concentrate 64 BX, 89.25 g cane sugar, 2.77 g Lemonic acid, flavors, stabilizers, citrate buffer (um Avoid tartar) and extracts, 883.38 g water, Carotenoid mixture: 8 mg%, vitamin C equivalent: 20 mg%.

The composition of the invention can also in one Milk / fat-water emulsion can be provided. in the Examples of such compositions are given below.

Example 3 Instant chocolate drink

One formulation (8-10% / l milk) contains: 67% cane zuc ker / sugar, 30% cocoa powder, 1% lecithin and 2% satia gum, Carotenoid mixture, 6 mg%, vitamin E, E. E. (α-tocopherol Equivalent) 6 mg%, coenzyme Q10.

Example 4 Vegetarian milk base: Pina Colada

The drink contains 5% coconut oil, 0.1% emulsifiers, 8-10% Sugar, 0.1% Pina Colada flavor and active ingredients such as in the previous examples.

Example 5 Ice cream

An ice cream can contain about 10% fat, 12% fat-free Milk solids, 15% sugar, 3% corn syrup (color) extracts and flavors and active ingredients as in the previous examples.

Example 6 Raspberry ice cream buttermilk

61.45% buttermilk, 15.5% raspberry pulp, 14% cane zuc ker, 6% corn syrup, 3% butter, 0.2% emulsifier (lecithin), 0.2% stabilizers, e.g. Lygomme ELB (pH 3.8-4.0), active Ingredients as in the previous examples.

Example 7 Chamomile summer punch (tonic)

A strong infusion (concentrated hot water herbal extract with or without 1/4 ethanol) with pineapple, papaya and honey. Add mint and strawberry cubes for color and taste. Ak active ingredients as stated above.

Example 8 Herbs (mint) drops

Strong infusion: 4-8 teaspoons of peppermint in 1 cup boiling water, brewing the infusion in a covered cool container for a few hours. 50 drops at a time Add lemonade drink. Active ingredients as mentioned above give.

Example 9 Teas

Rose fruit (rose hip) tea blend (cold vitamin C drink): 1 cup of rose fruits (rose hips), 1 cinnamon stick approx.7.6 cm (3 inch), 1/4 cup dried lemon balm leaves, 1 teaspoon dried grated natural lemon peel.

Rose fruit and blackberry liqueur: 2 tea bags of rose fruits (pompadour brand), 1-2 teaspoons of blackberry liqueur, 1 cup of boiling Water. Brew together and serve.

Peppermint-alfalfa tea blend: 1 cup of peppermint or spearmint or horse mint leaves (bee balm), 1 cup dried Alfalfa leaves.

Active ingredients as stated above.

Example 10 Lemon-mint mixture

Water preparation: 1/2 cup dried peppermint leaves, 1 Cup of dried alfalfa leaves, 3 tablespoons of dried Lemon balm leaves, 3 tablespoons of dried, grated Lemon peel. Solids: 1 teaspoon (250 g Cane sugar / l). Active ingredients as stated above.

Example 11 Barley tea blend

About 1.1 l (2 pints) of barley tea (113 to 125 g (4 ounces) Barley, whole, 56 to 63 g (2 ounces) honey, washed Lemon zest of 1/2 lemon: add approx. 0.55 l (1st pint) water to barley and lemon peel. Simmer up both are soft. Remove from the heat source. Pull  to let. Add honey.), Approx. 0.55 l (1 pint) of hot water, 70-78 g (2 1/2 ounces) sliced figs, 14-32 g (1/2 ounce) crushed licorice root, 70-78 g (2 1/2 ounces) sliced raisins. Boil down to approx 1.1 l (2 pints). Strain. Active ingredients as above specified.

Example 12 Ginger lemonade

1 large piece of crushed ginger root, approx. 0.55 l (1 pint) boiling water, 1 teaspoon of honey, mineral water (Perrier Water) as needed, boil water, crushed ginger root add and let simmer for 15 to 20 min. root strain. Add honey and mix well. With mineral water (Perrier water) unite. No powdered ginger use. Active ingredients as stated above.

Example 13 Powdered beverages

"Orange flavor": (Values expressed as a percentage / content in a consumer preparation): 10% sugar, 1% carotene mixture (A dietary drink should contain 1/200 aspartame or 1/250 acesulfame). 0.1% citric acid, 0.9% flavorings, 0.1-0.2% stabilizers (CMC, guargum etc.), buffer - Na ₃ citrate extracts.

As can be seen from the examples above, this is Manufacture of an inventive Carotenoid mix drink simple and economical. It should be understood from the above that the Meaning of the words "soft drink beverage" and "beverage", see above as used in the present description  also frozen or semi-frozen liquids like Include ice creams and sorbets.

Example 14 Fruit ice cream and strawberry sorbet

21.5% cane sugar, 6.5% corn syrup (DE 36-38), 24.15% strawberry puree, 2.5% strawberry concentrate, 0.35% Satia Algin GAX-900. pH 3.3-3.5, 45% water.

Herbal juice and pineapple: mint, alfalfa, filaree, dandelion, Leaves of Lactuca sativa longifolia (Romaine leaves), pe tersilie, celery herb, carrot herb, 2 cups of pineapple: each combine a handful and extract juice. These herbs and handfuls of home plants into the juice extractor 1 cup for every 2 cups of pineapple. This green juice can processed into ice cubes and then used. Give otherwise active ingredients can be used as stated above be applied.

The nutritional and RDA data for the components of the inventions Beverages according to the invention are well known to those skilled in the art and are modified change from time to time. Clarifying data are un ten specified. They are based on values at the time of Filing of this application accepted are: RDA was formerly in International Units, I.E. (I.U.) defined, defined as 0.3 µg crystalline all-trans reti nol or 0.6 µg β-carotene. RDA has been working on vitamin A since 1980 generally in µg and R.E. specified. For an adult The RDA is set to 1,000 RE (750 as retinol and 250 as β-carotene, 5000 IU), while the RDA for Women is set at 800 RE (4000 IU) lower. Children need 400 to 1000 RE (2000 to 5000 IU), increasing from early childhood to the age of 14  Years. The amount of β-carotene required for 1 RE is 6 µg, while the amount of other provitamin A-carotenoids is 12 µg. 1 RDA carotene is that Provitamin A equivalent of 5000 IU Vitamin A.

Claims (10)

1. Sunscreen composition on liquid Base with a carotenoid mixture, alone or in an admixture of vitamin C and / or vitamin E. and / or other physiologically acceptable atioxidan tien, the content of these substances 10 RDA Vitamin A- Equivalents of provitamin A-active carotenoids per Liter of liquid does not exceed. 2. Sunscreen composition according to claim 1, because characterized in that the composition in rivers in a drinkable form. 3. Sunscreen composition according to claim 1, because characterized in that the composition in frozen Rener or semi-frozen form is present. 4. Sunscreen composition according to one of the An sayings 1 to 3, characterized in that the together up to 10 RDA carotenoid equivalents and Has vitamin C. 5. Sunscreen composition according to one of the An sayings 1 to 3, characterized in that the together up to 10 RDA carotenoid equivalents and Has vitamin E. 6. Sunscreen composition according to one of the above forthcoming claims, characterized in that the Composition still biologically acceptable flavors and / or additives.   7. Sunscreen composition according to one of the above forthcoming claims, characterized in that the Flavors include one or more invigorating herbs selected from the group consisting of: cucumber herb, Aloe vera, peppermint, lime / lemon, ginseng, ger stentee (Barley water), anise, grapefruit, raspberries, Strawberries, hawthorn berries, rosemary, watercress, Guarana, Papavera rhoea, Achila milfolia, Arcitium lap paa, chrysanthemum, parthenium, cola vera, elenthero coccus, bingo bilboa and Japanese apricot (UMA). 8. Dried or concentrated extract for the manufacture len of a sun protection food, characterized thereby records that the extract carotenoids alone or in Admixture with vitamin C in a water base-Zu preparation and / or vitamin E in a milk base Preparation has. 9. Sunscreen composition according to one of the An sayings 1 to 8, characterized in that the together antioxidants and / or radical scavengers having. 10. Sunscreen composition according to one of the types sayings 1 to 9, characterized in that the together composition as water or milk base or in emulsified form is present.