DE3700924C2 - Use of active ingredient combinations for combating botrytis monilia and sclerotinia species - Google Patents

Description

The present invention relates to the use of combinations of active ingredients, those from the known 1- (4-chlorophenyl) -4,4-dimethyl-3- (1,2,4-triazol-1-yl- methyl) -pentan-3-ol on the one hand and certain known fungicidal active ingredients on the other hand, to combat botrytis, monilia and Sclerotinia species.

Combinations of 1- (4-chlorophenyl) -4,4- are known from EP-OS 0 135 854 dimethyl-3- (1,2,4-triazol-1-yl-methyl) -pentan-3-ol (= tebuconazole) and others Fungicidal components known. As a possible mixed partner including N, N-dimethyl-N'-phenyl- (N'-fluorodichloromethylthio) sulfamide (= Dichlofluanide) and 1,2-dimethylcyclopropane-1,2-dicarboxylic acid-3,5-dichlorophenylimide (= Procymidone) called. There is also the Indication that mixtures of tebuconazole and other fungicides against numerous phytopathogenic mushrooms can be used. However, it will neither the use of tebuconazole in a mixture with dichlofluanid or Procymidone still use any other combination of tebuconazole especially for combating Botrytis, Monilia or Sclerotinia species described.

From DE-OS 25 52 967 and the communication in Chem. Abstr. 105, 74 383 k (1986) shows that mixtures of certain 1,2,4-triazoles and other fungicidal agents used against phytopathogenic fungi can be. However, the azole component is completely different significantly from the tebuconazole. So in the cited publications No azole derivatives mentioned, in which the 1,2,4-triazolyl radical via a CH₂ group is connected to the carbinol carbon atom.

It has now been found that the active ingredient combinations out

• a) 1- (4-Chlorophenyl) -4,4-dimethyl-3- (1,2,4-triazol-1-yl-methyl) -pentan-3-ol of the formula and
• b) N, N-dimethyl-N'-phenyl- (N'-fluorodichloromethylthio) - sulfamide of the formula or 1,2-dimethyl-cyclopropane-1,2-dicarboxylic acid-3,5-dichlorophenylimide of the formula 1 to 10 parts by weight of active compound of formula (II) or 0.5 to 5 parts by weight of active compound of formula (III) are contained in the active compound combinations per 1 part by weight of active compound of formula (I),

very good for combating botrytis, monilia and Sclerotinia species are suitable.

Surprisingly, the effectiveness of the invention Active substance combinations in the indicated indications much higher than the sum of the effects of the individual active ingredients. So it's an unpredictable one synergistic effect before and not only an addition. Furthermore, the invention outperform Drug combinations surprisingly also the most constitutionally similar combinations known, the previously used for the same purpose were.

The contained in the active ingredient combinations according to the invention Active substances are already known (cf. EP-OS 00 40 345; R. Wegler "Chemistry of Plant Protection and Pesticides ", Volume 2, page 95, Springer Verlag Berlin / Heidelberg / New York, 1970 and K. H. Büchel "Plant Protection and Pest Control", pages 146 and 148, Georg Thieme Verlag, Stuttgart, 1977).

The active compound combinations according to the invention are suitable particularly good for combating botrytis species in viticulture, in soft fruit and in vegetable growing, also to combat of Monilia species in stone fruit growing and for combating of Sclerotinia species on different cultures, like rapeseed.  

The active compound combinations according to the invention can in the usual formulations are transferred, such as Solutions, emulsions, suspensions, powders, foams, Pastes, granules, aerosols, very fine encapsulations in polymeric substances and in coating compositions for seeds, as well ULV formulations.

These formulations are prepared in a known manner e.g. B. by mixing the active ingredient with extenders, i.e. liquid solvents, under pressure standing liquefied gases and / or solid carriers, optionally using surfactants Agents, ie emulsifiers and / or dispersants and / or foam-generating agents. In the event of the use of water as an extender can, for. Belly organic solvents used as auxiliary solvents become. Essentially come as liquid solvents in question: aromatics, such as xylene, toluene or alkylnaphthalenes, chlorinated aromatics or chlorinated aliphatic Hydrocarbons such as chlorobenzenes, chlorethylenes or Methylene chloride, aliphatic hydrocarbons, such as Cyclohexane or paraffins, e.g. B. petroleum fractions, alcohols, such as butanol or glycol and their ethers and esters, Ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone, strongly polar solvents, such as Dimethylformamide and dimethyl sulfoxide, as well as water. With liquefied gaseous extenders or carriers are meant such liquids, which in normal Temperature and under normal pressure are gaseous, for. B. Aerosol propellants, such as halogenated hydrocarbons as well Butane, propane, nitrogen and carbon dioxide. As fixed  Carriers come into question: z. B. natural stone powder, such as kaolins, clays, talc, chalk, quartz, Attapulgite, montmorillonite or diatomaceous earth and synthetic Rock powder, such as highly disperse silica, Alumina and silicates. As solid carriers for Granules are possible: B. broken and fractionated natural rocks such as calcite, marble, pumice, Sepiolite, dolomite and synthetic granules inorganic and organic flours and granules organic material such as sawdust, coconut shells, corn cobs and tobacco stems. As an emulsifier and / or foam generator Funds are possible: B. non-ionic and anionic emulsifiers, such as polyoxyethylene fatty acid esters, Polyoxyethylene fatty alcohol ether, e.g. B. alkylaryl polyglycol ether, Alkyl sulfonates, alkyl sulfates, aryl sulfonates and Protein hydrolyzates. Possible dispersants are: e.g. B. lignin sulfite and methyl cellulose.

In the formulations, adhesives such as carboxymethyl cellulose, natural and synthetic powdery, granular or latex-shaped polymers can be used, such as Gum arabic, polyvinyl alcohol, polyvinyl acetate, as well natural phospholipids such as cephalins and lecithins, and synthetic phospholipids. Other additives can mineral and vegetable oils.

Dyes such as inorganic pigments, e.g. B. Iron oxide, titanium oxide, ferrocyan blue and organic dyes, such as alizarin, azo and metal phthalocyanine dyes and trace nutrients, such as salts of iron, manganese, Boron, copper, cobalt, molybdenum and zinc can be used.  

The formulations generally contain between 0.1 and 95 percent by weight of active ingredient, preferably between 0.5 and 90%.

The active compound combinations according to the invention can in the formulations in admixture with other known ones Active substances are present, such as fungicides, insecticides, Acaricides and herbicides, as well as in mixtures with Fertilizers.

The active ingredient combinations as such, in the form their formulations or the use forms prepared from them, like ready-to-use solutions, emulsifiable Concentrates, emulsions, suspensions, wettable powders, soluble powders and granules.

The application is done in the usual way, e.g. B. by Pouring, spraying, spraying or dusting.

When treating parts of plants, the Active substance concentrations in the use forms in can be varied over a wide range. They are in the generally between 1 and 0.0001% by weight, preferably between 0.5 and 0.001%.

The good fungicidal activity of the active compound combinations according to the invention goes from the example below forth. While the individual active ingredients in the fungicidal The combinations show effect weaknesses an effect over a simple summation of effects goes out.  

Fungicides always have a synergistic effect then before if the fungicidal action of the active ingredient combinations is greater than the sum of the effects of individual applied active ingredients.

The expected effect for a given combination of two active ingredients can be calculated as follows (cf. Colby, SR "Calculating synergetic and antagonistic responses of herbicide combinations", Weeds 15, pages 20-22, 1967):
If

• X the disease infestation, expressed in% of the untreated control, when using the active ingredient A in a concentration of m ppm,
• Y the disease incidence, expressed in% of the untreated control, when using the active ingredient B in a concentration of n ppm and
• E means the expected disease incidence, expressed in% of the untreated control, when active ingredients A and B are used in concentrations of m and n ppm,

then

If the actual fungicidal effect is greater than calculated, the combination is superadditive in its effect, d. H. there is a synergistic effect. In this case, the infestation actually observed must be observed less than that from the above formula calculated value for the expected infestation (E).  

The table in the following example clearly shows shows that the effect found of the invention Drug combinations is greater than the calculated d. that is, there is a synergistic effect.

Example A Botrytis test (bean) / protective

For the preparation of a suitable preparation of active ingredient an injectable, commercially available active ingredient Formulation with water to the desired one Concentration diluted.

To test for protective efficacy one splashes young plants with the respective active ingredient preparation (individual active ingredients or combinations of active ingredients) to to dripping wet. After the spray coating has dried on 2 small botrytis cinerea overgrown on each leaf Pieces of agar placed on top. The inoculated plants will in a darkened, humid chamber at 20 ° C set up. 3 days after the inoculation, the size the infestation spots on the leaves were evaluated.

Active substances, active substance concentrations and test results are shown in the following table.

Table A

Botrytis test (bean) / protective

Claims (3)

1. Use of active ingredient combinations

• a) 1- (4-chlorophenyl) -4,4-dimethyl-3- (1,2,4-triazol-1-yl-methyl) -pentan-3-ol of the formula and
• b) N, N-dimethyl-N'-phenyl- (N'-fluorodichloromethylthio) - sulfamide of the formula or 1,2-dimethyl-cyclopropane-1,2-dicarboxylic acid-3,5-dichlorophenylimide of the formula

to combat botrytis, monilia and Sclerotinia species, being in the active ingredient combinations to 1 part by weight Active ingredient of formula (I) 1 to 10 parts by weight of active ingredient of formula (II) or 0.5 to 5 parts by weight of active ingredient Formula (III) are included. 2. Procedure for combating botrytis, monilia and Sclerotinia species, characterized in that that active ingredient combinations according to claim 1 the mushrooms and / or their habitat.