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DE3789430D1 - Homogenes fluortestverfahren mit abstoss des fluorzenten hintergrundes. - Google Patents

Homogenes fluortestverfahren mit abstoss des fluorzenten hintergrundes.

Info

Publication number
DE3789430D1
DE3789430D1 DE87905011T DE3789430T DE3789430D1 DE 3789430 D1 DE3789430 D1 DE 3789430D1 DE 87905011 T DE87905011 T DE 87905011T DE 3789430 T DE3789430 T DE 3789430T DE 3789430 D1 DE3789430 D1 DE 3789430D1
Authority
DE
Germany
Prior art keywords
repellation
fluorous
background
test method
homogeneous fluorine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE87905011T
Other languages
English (en)
Other versions
DE3789430T2 (de
Inventor
Irwin Wieder
Ron Hale
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter Healthcare Corp
Original Assignee
Baxter Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Diagnostics Inc filed Critical Baxter Diagnostics Inc
Application granted granted Critical
Publication of DE3789430D1 publication Critical patent/DE3789430D1/de
Publication of DE3789430T2 publication Critical patent/DE3789430T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/40—Rare earth chelates

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
DE3789430T 1986-06-17 1987-06-15 Homogenes fluortestverfahren mit abstoss des fluorzenten hintergrundes. Expired - Lifetime DE3789430T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87528786A 1986-06-17 1986-06-17
PCT/US1987/001407 WO1987007955A1 (en) 1986-06-17 1987-06-15 Homogeneous fluoroassay methods employing fluorescent background rejection and water-soluble rare earth metal chelate fluorophores

Publications (2)

Publication Number Publication Date
DE3789430D1 true DE3789430D1 (de) 1994-04-28
DE3789430T2 DE3789430T2 (de) 1994-10-27

Family

ID=25365527

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3789430T Expired - Lifetime DE3789430T2 (de) 1986-06-17 1987-06-15 Homogenes fluortestverfahren mit abstoss des fluorzenten hintergrundes.

Country Status (8)

Country Link
US (1) US6242268B1 (de)
EP (1) EP0272320B1 (de)
JP (1) JP2802921B2 (de)
CA (1) CA1309016C (de)
DE (1) DE3789430T2 (de)
DK (1) DK172464B1 (de)
FI (1) FI93997C (de)
WO (1) WO1987007955A1 (de)

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US6087088A (en) * 1997-01-31 2000-07-11 Bayer Corporation Binding assays using more than one label for determining analyte in the presence of interfering factors
US6344360B1 (en) 1998-03-11 2002-02-05 Sensors For Medicine And Science, Inc. Detection of analytes by fluorescent lanthanide metal chelate complexes containing substituted ligands
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DE60222008T2 (de) * 2001-11-30 2008-05-15 California Institute Of Technology, Pasadena Verbesserte methode zur quantitativen bestimmung von bakteriellen endosporen unter anwendung der lanthanid-dipicolinat-lumineszenz
US8367013B2 (en) 2001-12-24 2013-02-05 Kimberly-Clark Worldwide, Inc. Reading device, method, and system for conducting lateral flow assays
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US7314763B2 (en) * 2002-08-27 2008-01-01 Kimberly-Clark Worldwide, Inc. Fluidics-based assay devices
US7285424B2 (en) 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
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US7611862B2 (en) * 2004-11-12 2009-11-03 California Institute Of Technology Method and apparatus for detecting and quantifying bacterial spores on a surface
US7563615B2 (en) * 2005-04-15 2009-07-21 California Institute Of Technology Apparatus and method for automated monitoring of airborne bacterial spores
US20070117175A1 (en) * 2005-06-17 2007-05-24 Adrian Ponce Airborne bacterial spores as an indicator of biomass in an indoor environment
US7608419B2 (en) * 2003-11-13 2009-10-27 California Institute Of Technology Method and apparatus for detecting and quantifying bacterial spores on a surface
US7247500B2 (en) * 2002-12-19 2007-07-24 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in membrane-based assay devices
US20040197819A1 (en) 2003-04-03 2004-10-07 Kimberly-Clark Worldwide, Inc. Assay devices that utilize hollow particles
US7851209B2 (en) * 2003-04-03 2010-12-14 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in assay devices
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US7943395B2 (en) 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US7713748B2 (en) 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
US20050112703A1 (en) 2003-11-21 2005-05-26 Kimberly-Clark Worldwide, Inc. Membrane-based lateral flow assay devices that utilize phosphorescent detection
US7943089B2 (en) 2003-12-19 2011-05-17 Kimberly-Clark Worldwide, Inc. Laminated assay devices
US7815854B2 (en) * 2004-04-30 2010-10-19 Kimberly-Clark Worldwide, Inc. Electroluminescent illumination source for optical detection systems
US7796266B2 (en) * 2004-04-30 2010-09-14 Kimberly-Clark Worldwide, Inc. Optical detection system using electromagnetic radiation to detect presence or quantity of analyte
US20050244953A1 (en) * 2004-04-30 2005-11-03 Kimberly-Clark Worldwide, Inc. Techniques for controlling the optical properties of assay devices
US20060019265A1 (en) * 2004-04-30 2006-01-26 Kimberly-Clark Worldwide, Inc. Transmission-based luminescent detection systems
US7521226B2 (en) 2004-06-30 2009-04-21 Kimberly-Clark Worldwide, Inc. One-step enzymatic and amine detection technique
US7906276B2 (en) * 2004-06-30 2011-03-15 Kimberly-Clark Worldwide, Inc. Enzymatic detection techniques
US7094528B2 (en) * 2004-06-30 2006-08-22 Kimberly-Clark Worldwide, Inc. Magnetic enzyme detection techniques
US20070121113A1 (en) * 2004-12-22 2007-05-31 Cohen David S Transmission-based optical detection systems
US7939342B2 (en) 2005-03-30 2011-05-10 Kimberly-Clark Worldwide, Inc. Diagnostic test kits employing an internal calibration system
US7803319B2 (en) * 2005-04-29 2010-09-28 Kimberly-Clark Worldwide, Inc. Metering technique for lateral flow assay devices
US7858384B2 (en) * 2005-04-29 2010-12-28 Kimberly-Clark Worldwide, Inc. Flow control technique for assay devices
US7439079B2 (en) * 2005-04-29 2008-10-21 Kimberly-Clark Worldwide, Inc. Assay devices having detection capabilities within the hook effect region
US7504235B2 (en) * 2005-08-31 2009-03-17 Kimberly-Clark Worldwide, Inc. Enzyme detection technique
US7829347B2 (en) * 2005-08-31 2010-11-09 Kimberly-Clark Worldwide, Inc. Diagnostic test kits with improved detection accuracy
US7279136B2 (en) 2005-12-13 2007-10-09 Takeuchi James M Metering technique for lateral flow assay devices
US7645583B2 (en) * 2005-12-14 2010-01-12 Kimberly-Clark Worldwide, Inc. Identification of compounds for inhibiting complexation of C-reactive protein with fibronectin
US7618810B2 (en) * 2005-12-14 2009-11-17 Kimberly-Clark Worldwide, Inc. Metering strip and method for lateral flow assay devices
US7745158B2 (en) * 2005-12-14 2010-06-29 Kimberly-Clark Worldwide, Inc. Detection of secreted aspartyl proteases from Candida species
US8758989B2 (en) * 2006-04-06 2014-06-24 Kimberly-Clark Worldwide, Inc. Enzymatic detection techniques
US7897360B2 (en) 2006-12-15 2011-03-01 Kimberly-Clark Worldwide, Inc. Enzyme detection techniques
US7998414B2 (en) * 2007-02-28 2011-08-16 Corning Incorporated System for high throughput GPCR functional assay
US8535617B2 (en) * 2007-11-30 2013-09-17 Kimberly-Clark Worldwide, Inc. Blood cell barrier for a lateral flow device
FI20095302A0 (fi) * 2009-03-24 2009-03-24 Arctic Partners Oy Ab Luminesenssimääritysmenetelmä
WO2015165826A1 (en) 2014-05-02 2015-11-05 Drh Finland Oy New chromophoric structures for lanthanide chelates field of the invention
US11112409B2 (en) 2016-02-12 2021-09-07 The Regents Of The University Of California Systems and compositions for diagnosing pathogenic fungal infection and methods of using the same
CN109313198B (zh) 2016-06-09 2022-07-15 雷度米特图尔库公司 用于结合测定的背景阻断剂
WO2018187385A1 (en) 2017-04-03 2018-10-11 The Regents Of The University Of California Compositions and methods of diagnosing pancreatic cancer
FI130554B (en) 2020-01-20 2023-11-16 Oy Arctic Partners Ab LUMINESCENCE HYBRIDIZATION DETERMINATION METHOD

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CA1205028A (en) * 1981-07-01 1986-05-27 Jerald C. Hinshaw Fluorescent chelates and labeled specific binding reagents prepared therefrom
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Also Published As

Publication number Publication date
WO1987007955A1 (en) 1987-12-30
DE3789430T2 (de) 1994-10-27
CA1309016C (en) 1992-10-20
EP0272320A4 (de) 1989-08-09
FI880719L (fi) 1988-02-16
EP0272320A1 (de) 1988-06-29
JP2802921B2 (ja) 1998-09-24
FI93997C (fi) 1995-06-26
DK79888A (da) 1988-02-16
DK79888D0 (da) 1988-02-16
FI880719A0 (fi) 1988-02-16
DK172464B1 (da) 1998-08-31
EP0272320B1 (de) 1994-03-23
JPH01500458A (ja) 1989-02-16
FI93997B (fi) 1995-03-15
US6242268B1 (en) 2001-06-05

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Legal Events

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8364 No opposition during term of opposition