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DE3689769D1 - Multilamellare liposome mit verbesserter einschliessungswirkung. - Google Patents

Multilamellare liposome mit verbesserter einschliessungswirkung.

Info

Publication number
DE3689769D1
DE3689769D1 DE86904583T DE3689769T DE3689769D1 DE 3689769 D1 DE3689769 D1 DE 3689769D1 DE 86904583 T DE86904583 T DE 86904583T DE 3689769 T DE3689769 T DE 3689769T DE 3689769 D1 DE3689769 D1 DE 3689769D1
Authority
DE
Germany
Prior art keywords
including effect
multilamellar liposome
improved including
improved
multilamellar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE86904583T
Other languages
English (en)
Other versions
DE3689769T2 (de
Inventor
Marcel Bally
Pieter Cullis
Michael Hope
Andrew Janoff
Lawrence Mayer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elan Pharmaceuticals LLC
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Publication of DE3689769D1 publication Critical patent/DE3689769D1/de
Application granted granted Critical
Publication of DE3689769T2 publication Critical patent/DE3689769T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
DE3689769T 1985-07-05 1986-06-24 Multilamellare liposome mit verbesserter einschliessungswirkung. Expired - Fee Related DE3689769T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75242385A 1985-07-05 1985-07-05
US80054585A 1985-11-21 1985-11-21
PCT/US1986/001371 WO1987000043A1 (en) 1985-07-05 1986-06-24 Multilamellar liposomes having improved trapping efficiencies

Publications (2)

Publication Number Publication Date
DE3689769D1 true DE3689769D1 (de) 1994-05-11
DE3689769T2 DE3689769T2 (de) 1994-07-21

Family

ID=27115587

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3689769T Expired - Fee Related DE3689769T2 (de) 1985-07-05 1986-06-24 Multilamellare liposome mit verbesserter einschliessungswirkung.

Country Status (4)

Country Link
EP (1) EP0231261B1 (de)
JP (2) JP2579625B2 (de)
DE (1) DE3689769T2 (de)
WO (1) WO1987000043A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5897873A (en) * 1984-04-12 1999-04-27 The Liposome Company, Inc. Affinity associated vaccine
US5204112A (en) * 1986-06-16 1993-04-20 The Liposome Company, Inc. Induction of asymmetry in vesicles
US5252263A (en) * 1986-06-16 1993-10-12 The Liposome Company, Inc. Induction of asymmetry in vesicles
US4963297A (en) * 1987-12-22 1990-10-16 The Liposome Company, Inc. Spontaneous vesticulation of multilamellar liposomes
EP0414663A4 (en) * 1987-04-16 1991-07-17 The Liposome Company, Inc. Liposome continuous size reduction method and apparatus
US5262168A (en) * 1987-05-22 1993-11-16 The Liposome Company, Inc. Prostaglandin-lipid formulations
US5925375A (en) * 1987-05-22 1999-07-20 The Liposome Company, Inc. Therapeutic use of multilamellar liposomal prostaglandin formulations
WO1988009170A1 (en) * 1987-05-22 1988-12-01 The Liposome Company, Inc. Prostaglandin-lipid formulations
MX9203804A (es) * 1987-10-19 1992-07-01 Liposome Co Inc Sistemas farmaceuticos a base de tocoferol.
US5948441A (en) * 1988-03-07 1999-09-07 The Liposome Company, Inc. Method for size separation of particles
BE1001869A3 (fr) * 1988-10-12 1990-04-03 Franz Legros Procede d'encapsulation liposomiale d'antibiotiques aminoglucosidiques, en particulier de la gentamycine.
US5049392A (en) * 1989-01-18 1991-09-17 The Liposome Company, Inc. Osmotically dependent vesicles
US5100662A (en) * 1989-08-23 1992-03-31 The Liposome Company, Inc. Steroidal liposomes exhibiting enhanced stability
US5820848A (en) * 1990-01-12 1998-10-13 The Liposome Company, Inc. Methods of preparing interdigitation-fusion liposomes and gels which encapsulate a bioactive agent
US5525232A (en) * 1990-03-02 1996-06-11 The Liposome Company, Inc. Method for entrapment of cationic species in lemellar vesicles
DK148292D0 (da) * 1992-12-09 1992-12-09 Lundbeck & Co As H Forbindelser
JPH08510748A (ja) * 1993-05-21 1996-11-12 ザ リポソーム カンパニー、インコーポレーテッド リポソームが誘発する生理的副作用の低減
CA2126648C (en) * 1993-11-09 2000-10-10 Tomas De Paoli Liposomes containing bioavailable iron (ii) and method for obtaining them
US5902604A (en) * 1995-06-06 1999-05-11 Board Of Regents, The University Of Texas System Submicron liposome suspensions obtained from preliposome lyophilizates
CA2208215A1 (en) 1995-10-12 1997-04-17 Supergen, Inc. Liposome formulations of 5.beta. steroids
US6613352B2 (en) 1999-04-13 2003-09-02 Universite De Montreal Low-rigidity liposomal formulation
US7718189B2 (en) 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
ES2275443B1 (es) * 2005-11-30 2008-06-01 Italfarmaco, S.A. Procedimiento de preparacion de liposomas.
ES2594368T3 (es) 2005-12-08 2016-12-19 Insmed Incorporated Composiciones a base de lípidos de antiinfecciosos para tratar infecciones pulmonares
US20100196455A1 (en) 2007-05-04 2010-08-05 Transave, Inc. Compositions of Multicationic Drugs for Reducing Interactions with Polyanionic Biomolecules and Methods of Use Thereof
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
US20150272880A1 (en) 2012-05-21 2015-10-01 Insmed Incorporated Systems for treating pulmonary infections
ES2743039T3 (es) 2012-11-29 2020-02-18 Insmed Inc Formulaciones de vancomicina estabilizada
PT3142643T (pt) 2014-05-15 2019-10-28 Insmed Inc Métodos para o tratamento de infeções mico bacterianas pulmonares não tuberculares
US11571386B2 (en) 2018-03-30 2023-02-07 Insmed Incorporated Methods for continuous manufacture of liposomal drug products
KR20210024451A (ko) 2018-05-02 2021-03-05 인스메드 인코포레이티드 리포솜 약물 제형을 제조하는 방법
WO2022212863A1 (en) 2021-04-01 2022-10-06 Vestaron Corporation Liposome formulations for pesticide delivery and methods for producing and using the same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5186117A (en) * 1975-01-27 1976-07-28 Tanabe Seiyaku Co Johoseibiryushiseizainoseiho
JPS5492951A (en) * 1977-12-29 1979-07-23 Shionogi & Co Ltd Novel aminoglycoside derivative
JPS558488A (en) * 1978-07-05 1980-01-22 Mitsubishi Electric Corp Surface treating method of radiator
US4397846A (en) * 1981-05-15 1983-08-09 Murray Weiner Storage-stable lipid vesicles and method of preparation
WO1983003383A1 (en) * 1982-03-29 1983-10-13 Liposome Co Inc Stable plurilamellar vesicles
US4515736A (en) * 1983-05-12 1985-05-07 The Regents Of The University Of California Method for encapsulating materials into liposomes
CA1237671A (en) * 1983-08-01 1988-06-07 Michael W. Fountain Enhancement of pharmaceutical activity
US4532089A (en) * 1984-01-14 1985-07-30 Northwestern University Method of preparing giant size liposomes
GB8407557D0 (en) * 1984-03-23 1984-05-02 Hayward J A Polymeric lipsomes
JPS6150912A (ja) * 1984-08-16 1986-03-13 Shionogi & Co Ltd リポソ−ム製剤の製造法

Also Published As

Publication number Publication date
JP2579625B2 (ja) 1997-02-05
JPH08175975A (ja) 1996-07-09
WO1987000043A1 (en) 1987-01-15
EP0231261A1 (de) 1987-08-12
EP0231261B1 (de) 1994-04-06
EP0231261A4 (de) 1988-04-27
JPS63500798A (ja) 1988-03-24
DE3689769T2 (de) 1994-07-21
JP2566747B2 (ja) 1996-12-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee