DE3468104D1 - New aryloxypropanolamine derivatives, process for the preparation thereof, pharmaceutical compositions and therapeutic use - Google Patents
New aryloxypropanolamine derivatives, process for the preparation thereof, pharmaceutical compositions and therapeutic useInfo
- Publication number
- DE3468104D1 DE3468104D1 DE8484100085T DE3468104T DE3468104D1 DE 3468104 D1 DE3468104 D1 DE 3468104D1 DE 8484100085 T DE8484100085 T DE 8484100085T DE 3468104 T DE3468104 T DE 3468104T DE 3468104 D1 DE3468104 D1 DE 3468104D1
- Authority
- DE
- Germany
- Prior art keywords
- hydrogen
- preparation
- pharmaceutical compositions
- lower alkyl
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- 150000002431 hydrogen Chemical group 0.000 abstract 3
- 239000005977 Ethylene Chemical group 0.000 abstract 1
- 125000005529 alkyleneoxy group Chemical group 0.000 abstract 1
- 125000001951 carbamoylamino group Chemical group C(N)(=O)N* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- -1 methylendioxy group Chemical group 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT19219/83A IT1193608B (it) | 1983-01-21 | 1983-01-21 | Derivati di arilossipropanolamina,procedimento per la loro preparazione composizioni farmaceutiche che li contengono e loro impiego terapeutico |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3468104D1 true DE3468104D1 (en) | 1988-01-28 |
Family
ID=11155887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8484100085T Expired DE3468104D1 (en) | 1983-01-21 | 1984-01-06 | New aryloxypropanolamine derivatives, process for the preparation thereof, pharmaceutical compositions and therapeutic use |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4579861A (de) |
| EP (1) | EP0116825B1 (de) |
| JP (1) | JPS59139362A (de) |
| AT (1) | ATE31410T1 (de) |
| DE (1) | DE3468104D1 (de) |
| IT (1) | IT1193608B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL135487A (en) | 2000-04-05 | 2005-07-25 | Cupron Corp | Antimicrobial and antiviral polymeric materials and a process for preparing the same |
| US7296690B2 (en) | 2002-04-18 | 2007-11-20 | The Cupron Corporation | Method and device for inactivating viruses |
| US7364756B2 (en) | 2003-08-28 | 2008-04-29 | The Cuprin Corporation | Anti-virus hydrophilic polymeric material |
| US7480393B2 (en) | 2003-11-19 | 2009-01-20 | Digimarc Corporation | Optimized digital watermarking functions for streaming data |
| DE602005015475D1 (de) | 2004-11-09 | 2009-08-27 | Cupron Corp | Verfahren und materialien für die hautpflege |
| US9751830B2 (en) | 2010-03-15 | 2017-09-05 | The Trustees Of The University Of Pennsylvania | Inhibitors of the tumor necrosis factor receptor complex |
| IT202100000782A1 (it) | 2021-01-18 | 2022-07-18 | Procos Spa | Processo per la sintesi di imepitoina |
| EP4553066A1 (de) | 2023-11-10 | 2025-05-14 | Justesa Imagen S.A.U. | Verbessertes verfahren zur synthese von imepitopin |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE787103A (fr) * | 1971-08-04 | 1973-02-02 | Pfizer | Nouveaux derives de propanolamine et composition pharmaceutiqueles contenant |
| DE2644833A1 (de) * | 1976-10-05 | 1978-04-20 | Boehringer Sohn Ingelheim | Neue 1-aryloxy-2-hydroxy-3-alkylenaminopropane und verfahren zu ihrer herstellung |
| DK193181A (da) * | 1980-06-05 | 1981-12-06 | Hoffmann La Roche | Fremgangmaade til fremstilling af imidazolderivater |
| US4319032A (en) * | 1980-06-06 | 1982-03-09 | Alcolac Inc. | Derivatives of aminoalkyl alkylene ureas |
-
1983
- 1983-01-21 IT IT19219/83A patent/IT1193608B/it active
-
1984
- 1984-01-06 DE DE8484100085T patent/DE3468104D1/de not_active Expired
- 1984-01-06 EP EP84100085A patent/EP0116825B1/de not_active Expired
- 1984-01-06 AT AT84100085T patent/ATE31410T1/de not_active IP Right Cessation
- 1984-01-06 US US06/568,598 patent/US4579861A/en not_active Expired - Fee Related
- 1984-01-20 JP JP59009393A patent/JPS59139362A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0116825B1 (de) | 1987-12-16 |
| IT1193608B (it) | 1988-07-21 |
| US4579861A (en) | 1986-04-01 |
| ATE31410T1 (de) | 1988-01-15 |
| JPS59139362A (ja) | 1984-08-10 |
| EP0116825A1 (de) | 1984-08-29 |
| IT8319219A0 (it) | 1983-01-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |