DE19810965A1 - Nanopartikel, Verfahren zu ihrer Herstellung und ihre Verwendung - Google Patents

Nanopartikel, Verfahren zu ihrer Herstellung und ihre Verwendung

Info

Publication number: DE19810965A1
Authority: DE; Germany
Prior art keywords: nanoparticles; oxy; particles; polyelectrolyte complex; tris
Prior art date: 1998-03-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

DE1998110965

Other languages

German (de)

English (en)

Inventor

Javier Manero

Jennifer Filbey

Peter Boderke

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Aventis Research and Technologies GmbH and Co KG

Original Assignee

Aventis Research and Technologies GmbH and Co KG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-13

Filing date

1998-03-13

Publication date

1999-09-16

1998-03-13 Application filed by Aventis Research and Technologies GmbH and Co KG filed Critical Aventis Research and Technologies GmbH and Co KG

1998-03-13 Priority to DE1998110965 priority Critical patent/DE19810965A1/de

1999-03-06 Priority to CN 99803733 priority patent/CN1292687A/zh

1999-03-06 Priority to JP2000536370A priority patent/JP2002506814A/ja

1999-03-06 Priority to EP99911744A priority patent/EP1061904A1/fr

1999-03-06 Priority to PCT/EP1999/001452 priority patent/WO1999047130A1/fr

1999-03-06 Priority to AU30318/99A priority patent/AU3031899A/en

1999-09-16 Publication of DE19810965A1 publication Critical patent/DE19810965A1/de

Status Withdrawn legal-status Critical Current

Links

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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5192—Processes

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Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Nanotechnology (AREA)
Optics & Photonics (AREA)
Physics & Mathematics (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DE1998110965 1998-03-13 1998-03-13 Nanopartikel, Verfahren zu ihrer Herstellung und ihre Verwendung Withdrawn DE19810965A1 (de)

Priority Applications (6)

Application Number	Priority Date	Filing Date	Title
DE1998110965 DE19810965A1 (de)	1998-03-13	1998-03-13	Nanopartikel, Verfahren zu ihrer Herstellung und ihre Verwendung
CN 99803733 CN1292687A (zh)	1998-03-13	1999-03-06	毫微颗粒、毫微颗粒的制备方法及其应用
JP2000536370A JP2002506814A (ja)	1998-03-13	1999-03-06	ナノ粒子、ナノ粒子の製造法およびその使用
EP99911744A EP1061904A1 (fr)	1998-03-13	1999-03-06	Nanoparticules, leur procede de production et leur utilisation
PCT/EP1999/001452 WO1999047130A1 (fr)	1998-03-13	1999-03-06	Nanoparticules, leur procede de production et leur utilisation
AU30318/99A AU3031899A (en)	1998-03-13	1999-03-06	Nanoparticles, method for producing nanoparticles and use of the same

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE1998110965 DE19810965A1 (de)	1998-03-13	1998-03-13	Nanopartikel, Verfahren zu ihrer Herstellung und ihre Verwendung

Publications (1)

Publication Number	Publication Date
DE19810965A1 true DE19810965A1 (de)	1999-09-16

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ID=7860805

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE1998110965 Withdrawn DE19810965A1 (de)	1998-03-13	1998-03-13	Nanopartikel, Verfahren zu ihrer Herstellung und ihre Verwendung

Country Status (6)

Country	Link
EP (1)	EP1061904A1 (fr)
JP (1)	JP2002506814A (fr)
CN (1)	CN1292687A (fr)
AU (1)	AU3031899A (fr)
DE (1)	DE19810965A1 (fr)
WO (1)	WO1999047130A1 (fr)

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DE19952073A1 (de) *	1999-10-29	2001-07-12	Cognis Deutschland Gmbh	Verfahren zur Herstellung von nanopartikulären Chitosanen oder Chitosan-Derivaten
DE10118852A1 (de) *	2001-04-17	2002-10-31	Fricker Gert	Bdellosomen
WO2002096551A1 (fr) *	2001-05-31	2002-12-05	Novosom Ag	Microcapsules et nanocapsules solubles, procede de production associe et utilisation
DE10132669A1 (de) *	2001-07-05	2003-01-30	Fraunhofer Ges Forschung	Pharmakologische Zubereitung aus einem nanopartikulären mesomorphen Polyelektrolyt-Lipid-Komplex und mindestens einem Wirkstoff
WO2008152669A3 (fr) *	2007-06-11	2009-02-12	Univ Palermo	Vecteurs colloïdaux à structure polyaminoacide pour une libération orale de peptides et de protéines et leur méthode de production
WO2009035438A1 (fr) *	2007-09-13	2009-03-19	Janos Borbely	Nanoparticules polymériques obtenues par interactions ion-ion
WO2008093195A3 (fr) *	2007-01-29	2009-09-11	Medipol Sa	Particules colloïdales à base de chitosane pour la délivrance d'arn
EP2197457A4 (fr) *	2007-09-26	2010-10-27	Aparna Biosciences	Produit thérapeutique et compositions de nanoparticules de polyélectrolyte de vaccin
US20110287067A1 (en) *	2010-05-24	2011-11-24	University Of Utah Research Foundation	Reinforced adhesive complex coacervates and methods of making and using thereof
US9272069B2 (en)	2008-01-24	2016-03-01	University Of Utah Research Foundation	Adhesive complex coacervates and methods of making and using thereof
US9421300B2 (en)	2010-11-12	2016-08-23	University Of Utah Research Foundation	Simple coacervates and methods of use thereof
US9913927B2 (en)	2014-07-14	2018-03-13	University Of Utah Research Foundation	In situ solidifying complex coacervates and methods of making and using thereof
US9913926B2 (en)	2008-01-24	2018-03-13	University Of Utah Research Foundation	Adhesive complex coacervates and method of making and using thereof
US10077324B2 (en)	2013-02-06	2018-09-18	Kci Licensing, Inc.	Polymers, preparation and use thereof
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WO2001036000A1 (fr)	1999-11-15	2001-05-25	Bio Syntech Canada, Inc.	Solution biopolymere aqueuse auto-gelifiante en fonction du ph et a temperature controlee
ATE481110T1 (de) *	2002-07-16	2010-10-15	Biosyntech Canada Inc	Zusammensetzung für die herstellung zellkompatibler, injizierbarer, selbstgelierender chitosan lösungen zum einkapseln und verabreichen von lebenden zellen oderbiologisch aktiven faktoren
EP1548439A4 (fr) *	2002-09-13	2008-04-23	Hitachi Chemical Co Ltd	Porteur de fixation et phase solide
ES2246694B1 (es)	2004-04-29	2007-05-01	Instituto Cientifico Y Tecnologico De Navarra, S.A.	Nanoparticulas pegiladas.
ES2246695B1 (es)	2004-04-29	2007-05-01	Instituto Cientifico Y Tecnologico De Navarra, S.A.	Composicion estimuladora de la respuesta inmunitaria que comprende nanoparticulas a base de un copolimero de metil vinil eter y anhidrido maleico.
CN101396351B (zh) *	2007-09-28	2011-04-27	上海交通大学医学院附属瑞金医院	可响应磷酸酶浓度的载药聚电解质胶囊及其制备方法
EP2266546A1 (fr)	2009-06-08	2010-12-29	Advancell Advanced in Vitro Cell Technologies,S.A.	Procédé pour la préparation de systèmes colloïdaux pour la livraison de composés actifs
CN102813937A (zh) *	2012-06-12	2012-12-12	天津大学	含有疏水性药物的聚电解质复合物及其制备方法和应用
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EP0454044B1 (fr) *	1990-04-25	1995-12-06	Hoechst Aktiengesellschaft	Produit pharmacologique contenant des composés de polyélectrolytes sous forme de microparticules et au moins un agent actif
NZ242220A (en) *	1991-04-02	1994-04-27	Biotech Australia Pty Ltd	Complex for oral delivery of a substance to the circulatory or lymphatic drainage system comprising microparticle coupled to at least one carrier, the substance being encapsulated by the microparticle
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WO1999018934A1 (fr) *	1997-10-09	1999-04-22	Vanderbilt University	Dispositif d'administration de microparticules ou de nanoparticules de polymeres

1998
- 1998-03-13 DE DE1998110965 patent/DE19810965A1/de not_active Withdrawn
1999
- 1999-03-06 CN CN 99803733 patent/CN1292687A/zh active Pending
- 1999-03-06 AU AU30318/99A patent/AU3031899A/en not_active Abandoned
- 1999-03-06 EP EP99911744A patent/EP1061904A1/fr not_active Withdrawn
- 1999-03-06 WO PCT/EP1999/001452 patent/WO1999047130A1/fr not_active Ceased
- 1999-03-06 JP JP2000536370A patent/JP2002506814A/ja active Pending

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DE19952073A1 (de) *	1999-10-29	2001-07-12	Cognis Deutschland Gmbh	Verfahren zur Herstellung von nanopartikulären Chitosanen oder Chitosan-Derivaten
DE10118852A1 (de) *	2001-04-17	2002-10-31	Fricker Gert	Bdellosomen
WO2002096551A1 (fr) *	2001-05-31	2002-12-05	Novosom Ag	Microcapsules et nanocapsules solubles, procede de production associe et utilisation
DE10132669A1 (de) *	2001-07-05	2003-01-30	Fraunhofer Ges Forschung	Pharmakologische Zubereitung aus einem nanopartikulären mesomorphen Polyelektrolyt-Lipid-Komplex und mindestens einem Wirkstoff
DE10132669B4 (de) *	2001-07-05	2008-08-07	Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.	Pharmakologische Zubereitung aus einem nanopartikulären mesomorphen Polyelektrolyt-Lipid-Komplex und mindestens einem Wirkstoff
WO2008093195A3 (fr) *	2007-01-29	2009-09-11	Medipol Sa	Particules colloïdales à base de chitosane pour la délivrance d'arn
WO2008152669A3 (fr) *	2007-06-11	2009-02-12	Univ Palermo	Vecteurs colloïdaux à structure polyaminoacide pour une libération orale de peptides et de protéines et leur méthode de production
WO2009035438A1 (fr) *	2007-09-13	2009-03-19	Janos Borbely	Nanoparticules polymériques obtenues par interactions ion-ion
EP2197457A4 (fr) *	2007-09-26	2010-10-27	Aparna Biosciences	Produit thérapeutique et compositions de nanoparticules de polyélectrolyte de vaccin
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Also Published As

Publication number	Publication date
AU3031899A (en)	1999-10-11
EP1061904A1 (fr)	2000-12-27
JP2002506814A (ja)	2002-03-05
CN1292687A (zh)	2001-04-25
WO1999047130A1 (fr)	1999-09-23

Publication	Publication Date	Title
DE19810965A1 (de)	1999-09-16	Nanopartikel, Verfahren zu ihrer Herstellung und ihre Verwendung
DE69812887T2 (de)	2003-12-18	Mikropartikel aus chitosan-gelatin a
Sinha et al.	2004	Chitosan microspheres as a potential carrier for drugs
DE69221568T2 (de)	1998-03-19	Systeme zur oralen freisetzung von mikropartikeln
DE69927841T2 (de)	2006-07-13	Partikel auf polyaminosäure(n)basis sowie deren herstellungsverfahren
DE60035211T2 (de)	2008-02-21	Mikrokugeln mit kontinuierlicher Freisetzung
DE10121982B4 (de)	2008-01-24	Nanopartikel aus Protein mit gekoppeltem Apolipoprotein E zur Überwindung der Blut-Hirn-Schranke und Verfahren zu ihrer Herstellung
EP0454044B1 (fr)	1995-12-06	Produit pharmacologique contenant des composés de polyélectrolytes sous forme de microparticules et au moins un agent actif
DE69516296T2 (de)	2000-11-23	Herstellung von proteinmikrospähren, filmen und beschichtungen
DE69718470T2 (de)	2003-11-06	Verfahren und zubereitungen zum verbessern der bioadhäsiv-eigenschaften von polymeren unter verwendung organischer excipienten
DE102005062440B4 (de)	2011-02-24	Proteinbasiertes Trägersystem zur Resistenzüberwindung von Tumorzellen
DE112006002617T5 (de)	2008-08-28	Verfahren zur Herstellung von Core-Shell-Kompositen bzw. Kern-Hüllen-Kompositen mit vernetzten Hüllen und daraus entstehende Core-Shell-Komposite
WO2005032512A2 (fr)	2005-04-14	Capsules de films polymeres neutres a multiples couches associees par liaison d'hydrogene
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WO2004030649A2 (fr)	2004-04-15	Procede pour preparer et stabiliser des microsuspensions et des nanosuspensions au moyen d'amphiphiles et de polyelectrolytes
JP2008297288A (ja)	2008-12-11	微粒子および製造方法
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JP2006241321A (ja)	2006-09-14	キトサンナノ粒子の製造方法、キトサン粒子、コーティング用組成物、徐放性製剤、注射剤
RU2256440C2 (ru)	2005-07-20	Фармацевтический препарат
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