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DE19643813A1 - Kit for controlled injection of drugs - Google Patents

Kit for controlled injection of drugs

Info

Publication number
DE19643813A1
DE19643813A1 DE19643813A DE19643813A DE19643813A1 DE 19643813 A1 DE19643813 A1 DE 19643813A1 DE 19643813 A DE19643813 A DE 19643813A DE 19643813 A DE19643813 A DE 19643813A DE 19643813 A1 DE19643813 A1 DE 19643813A1
Authority
DE
Germany
Prior art keywords
preferred
kit according
controller
actuator
piston
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19643813A
Other languages
German (de)
Inventor
Hans Dr Dr Schreiber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
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Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to DE19643813A priority Critical patent/DE19643813A1/en
Publication of DE19643813A1 publication Critical patent/DE19643813A1/en
Withdrawn legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01D—MEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
    • G01D5/00—Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable
    • G01D5/26—Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable characterised by optical transfer means, i.e. using infrared, visible, or ultraviolet light
    • G01D5/32—Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable characterised by optical transfer means, i.e. using infrared, visible, or ultraviolet light with attenuation or whole or partial obturation of beams of light
    • G01D5/34—Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable characterised by optical transfer means, i.e. using infrared, visible, or ultraviolet light with attenuation or whole or partial obturation of beams of light the beams of light being detected by photocells
    • G01D5/347—Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable characterised by optical transfer means, i.e. using infrared, visible, or ultraviolet light with attenuation or whole or partial obturation of beams of light the beams of light being detected by photocells using displacement encoding scales
    • G01D5/34746—Linear encoders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3125—Details specific display means, e.g. to indicate dose setting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3306—Optical measuring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3379—Masses, volumes, levels of fluids in reservoirs, flow rates
    • A61M2205/3389—Continuous level detection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A61M5/1684—Monitoring, detecting, signalling or eliminating infusion flow anomalies by detecting the amount of infusate remaining, e.g. signalling end of infusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31556—Accuracy improving means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31573—Accuracy improving means

Landscapes

  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The kit comprises an injection syringe (1) or other injection device with an adaptable add-on electronic control system (2). This calculates the flow of the drug, indicates it, provides an alarm (6) if the injection is incorrect and, if required, a control element (7) corrects it. The control system can determine incrementally and-or decrementally, preferably in binary form, the longitudinal displacement of the piston. The piston can be motor driven by the control system according to a preset programme with the electrical connections formed by sliding contacts.

Description

Exakt dosierte Medikamentenapplikationen finden in zunehmendem Maße Bedeutung; sei es bei der Einzelinjektion bei kurz-, mittel- oder langdauernden Injektionen oder Infusionen, die über Injektomaten oder Infusiomaten nach Programmierung gesteuert werden.Exactly dosed medication applications can be found in increasing importance; be it with single injection for short, medium or long injections or Infusions following injectors or infusiomats Programming can be controlled.

Der Sinn der vorliegenden Erfindung besteht darin, alle Applikationsformen elektronisch zu kontrollieren bzw. zu steuern.The purpose of the present invention is all To control application forms electronically Taxes.

So dient ein bevorzugter Regler dazu, eine Einzelinjektion zu überwachen, gleichzeitig ist er bei entsprechenden Spritzengrößen aber als Regelglied angedacht, der nach Soll-Ist-Vergleich im Sinne eines kybernetischen Reglers ein Stellglied nach Kontaktierung ansteuert.For example, a preferred controller is used for a single injection to monitor, he is at the Syringe sizes but considered as a control element, according to Target-actual comparison in the sense of a cybernetic controller controls an actuator after contacting.

Der bevorzugte Kolbenverschub mag dabei über einen Elektromotor bevorzugt mittels elastischer Welle, pneumatisch oder dgl. geregelt erfolgen, wobei bei Injektomaten die Spritze in einer optimierten Halte- und Kolbenverfahrvorrichtung fixiert ist.The preferred piston displacement may be over one Electric motor preferably by means of an elastic shaft, controlled pneumatically or the like Injectomat the syringe in an optimized holding and Piston traversing device is fixed.

Dabei besteht darüber hinaus die Möglichkeit, z. B. Mehrfachinjektomaten zu konzipieren, die über einen jeweils bevorzugt separaten Antrieb z. B. über einen übergeordneten Prozessor gesondert angesteuert werden.There is also the possibility, for. B. To design multiple injectors, each one preferably separate drive z. B. via a parent Processor can be controlled separately.

Auf alternative Medikamentenkompartimente soll weiter nicht eingegangen werden.Alternative drug compartments should not go on To be received.

Die Erfindung wird nun beispielhaft anhand der Ansprüche und der Fig. 1 und 2 näher erläutert. The invention will now be explained in more detail by way of example with reference to the claims and FIGS. 1 and 2.

Dabei zeigtIt shows

Fig. 1 in schematisierter Schnittdarstellung den Gesamtbausatz, Fig. 1 in a schematic sectional view of the overall kit,

Fig. 2 in schematisierter, teilperspektifischer Darstellung den bevorzugten Regler nach dem Moir´-Prinzip in Anlehnung an Fig. 1. Fig. 2 in a schematic, partially perspective representation of the preferred controller according to the Moir 'principle based on Fig. 1st

Fig. 1 zeigt in schematisierter Schnittdarstellung den Gesamtbausatz. Wir erkennen Spritze (1) mit Zylinder (15), Kolben (24), Kolbenstange (11), Fingerstütze (26) und Daumenauflage (27). Die Kolbenstange (11) ist in bekannter Art kreuzförmig gestaltet und ebenso wie die Hauptspritzen­ komponenten aus bevorzugt Polyethylen im Spritzgußverfahren hergestellt, was sich insbesondere deshalb als Vorteil erweist, indem es sich lichttransparent darstellt. Fig. 1 shows a schematic sectional view of the overall kit. We recognize syringe ( 1 ) with cylinder ( 15 ), piston ( 24 ), piston rod ( 11 ), finger rest ( 26 ) and thumb rest ( 27 ). The piston rod ( 11 ) is designed in a cross-shaped manner and, like the main syringe components, is preferably made of polyethylene by injection molding, which has proven to be an advantage in particular by being transparent to light.

Bevorzugt im Bereich der Fingerstütze (26) ist der Regler (2) mit seinem Gehäuse (16) fixiert, das hier als erkennbare Merkmale Warn-LED (6), Programmierschalter (29) und den Schleif- und/oder Induktivkontakt (17) trägt, der hier nicht darstellbar mit dem Stellglied (7) zusammen­ wirkt, das das bevorzugte Antriebselement (20) steuert. Die Spritzenhalte- und -führungsvorrichtung (18, 30, 19, . . .) dient bei kurz- mittel- und langdauernden Injektionen dazu, einerseits die Spritze (1) z. B. am Infusionsständer zu fixieren (18), andererseits den Spritzenkolben (11) zu haltern (30) und sicher zu verfahren (19).The controller ( 2 ) is preferably fixed with its housing ( 16 ) in the area of the finger rest ( 26 ), which carries warning LEDs ( 6 ), programming switches ( 29 ) and the sliding and / or inductive contact ( 17 ) as recognizable features , which cannot be represented here, cooperates with the actuator ( 7 ) that controls the preferred drive element ( 20 ). The syringe holding and guiding device ( 18, 30, 19 ,...) Is used for short, medium and long-term injections, on the one hand the syringe ( 1 ) z. B. to fix on the IV pole ( 18 ), on the other hand to hold the syringe plunger ( 11 ) ( 30 ) and to move safely ( 19 ).

Gleichzeitig macht Fig. 1 noch erkennbar, daß der Strichmaßstab (9) hier von Seiten des Benutzers bevorzugt vor Gebrauch fixiert (28) wurde, während es dem Anmelder sinnvoll erscheint, den Strichmaßstab (9) herstellungs­ seitig bereits in optimaler Strichcodeteilung zu liefern.At the same time, Fig. 1 shows that the bar scale ( 9 ) was preferably fixed by the user before use ( 28 ), while it appears to the applicant to provide the bar scale ( 9 ) on the production side in an optimal bar code division.

Fig. 2 zeigt in schematischer, teilperspektifischer Darstellung den bevorzugten Regler (2) mit Kolbenstangen­ segment (10), adaptiertem und fixiertem Strichmaßstab (9), der besser als transparentes, plattenförmiges Teilungs­ codeelement (9) zu bezeichnen ist und auf der Abtastplatte (8) beim Kolbenverschub so verfährt, daß das über die bevorzugte Leucht-LED (12) erzeugte und bevorzugt über Lichtleiter (33) gelenkte Licht über Photodiode (13) als wechselnder Hell-Dunkel-Kontrast aufgenommen wird, der als Spannungsrechteckimpuls (23) an Mikroprozessor (3) mit Zähler (14) weitergegeben wird. Fig. 2 shows a schematic, partially perspective representation of the preferred controller ( 2 ) with piston rod segment ( 10 ), adapted and fixed line scale ( 9 ), which can be better described as a transparent, plate-shaped division code element ( 9 ) and on the scanning plate ( 8 ) moves during the piston displacement so that the light generated via the preferred light-emitting LED ( 12 ) and preferably directed via light guide ( 33 ) is received via photodiode ( 13 ) as an alternating light-dark contrast, which is transmitted to the microprocessor as a voltage square-wave pulse ( 23 ) ( 3 ) is passed on with counter ( 14 ).

Mittels Timer (5) gelingt die-Umrechnung der Kolbenverfahr­ geschwindigkeit und damit die Medikamentenflowberechnung, die ggf. über LED (6) als Fehler gemeldet und die über Stellglied (7) und Antriebselement (20) korrigiert wird.Using a timer ( 5 ), the piston travel speed can be converted and thus the drug flow calculation, which may be reported as an error via LED ( 6 ) and which is corrected via actuator ( 7 ) and drive element ( 20 ).

Hinzuweisen bleibt noch auf die bevorzugte und symbolisiert dargestellte bevorzugte Knopfzelle (22) und auf Kontakt (17).It remains to point out the preferred and symbolized preferred button cell ( 22 ) and contact ( 17 ).

Alternativen und insbesondere bevorzugte Anwendungsbei­ spiele sind den Ansprüchen zu entnehmen.Alternatives and particularly preferred application games can be found in the claims.

Claims (17)

1. Bausatz zur gesteuerten Medikamentenapplikation, dadurch gekennzeichnet, daß dieser neben einer Injektionsspritze (1) oder einer alternativen Applikationsvorrichtung zur Funktionsausführung aus einer adaptier- und fixierbaren Regelelektronik (2) besteht, die geeignet ist, den Medikamentenflow zu errechnen (3, 5), anzuzeigen (14), Fehlinjektionen zu melden (6) und bei Bedarf über ein Stellglied (7) zu korrigieren.1. Kit for controlled medication application, characterized in that, in addition to an injection syringe ( 1 ) or an alternative application device for carrying out the function, it consists of adaptable and fixable control electronics ( 2 ) which is suitable for calculating the medication flow ( 3, 5 ), display ( 14 ), report incorrect injections ( 6 ) and correct if necessary using an actuator ( 7 ). 2. Bausatz nach Anspruch 1, dadurch gekennzeichnet, daß der Regler (2) geeignet ist, bevorzugt inkremental und/oder dekremental und bevorzugt binär den longitudinalen Kolbenverschub zu ermitteln (8, 9).2. Kit according to claim 1, characterized in that the controller ( 2 ) is suitable, preferably incrementally and / or decrementally and preferably binary to determine the longitudinal piston displacement ( 8, 9 ). 3. Bausatz nach mindestens einem der Ansprüche 1, 2, dadurch gekennzeichnet, daß bei der inkrementalen/dekrementalen Meßmethode nach dem bevorzugten Moir´-Prinzip der/die bevorzugte/n Strichmaßstab/stäbe (9) (Durchlichtmaßstab) auf mindestens einem lichttransparenten Kolbenstangensegment (10) bevorzugt wieder abnehmbar fixierbar ist/sind und dort bevorzugt den gesamten Verfahrweg der Kolbenstange (11) einnimmt, während die bevorzugte/n Lichtquelle/n (12) ggf. mit Lichtleiter/n (33) und Kondensorlinse, die Abtastplatte/n (8), die Fotodiode/n (13), der/die Zähler (14), der/die Timer (5), der/die Mikroprozessor/en (3) mit Rechenwerk bevorzugt so am Spritzenzylinder (15, 26) mit dem entsprechenden Gehäuse (16) fixierbar als Regler (2) dienen und geeignet sind, mindestens ein Stellglied (7) anzusteuern, wobei bevorzugt zusätzlich mindestens ein Komparator und ein Richtungsdiskriminator Verwendung finden.3. Kit according to at least one of claims 1, 2, characterized in that in the incremental / decremental measuring method according to the preferred Moir 'principle / the preferred / n / ruler (s) ( 9 ) (transmitted light scale) on at least one light-transparent piston rod segment ( 10 ) is / are preferably detachably fixable and preferably occupies the entire travel of the piston rod ( 11 ), while the preferred light source (s) ( 12 ) optionally with light guide (s) ( 33 ) and condenser lens, the scanning plate (s) ( 8 ), the photodiode (s) ( 13 ), the counter ( 14 ), the timer ( 5 ), the microprocessor (s) ( 3 ) with arithmetic unit, preferably on the syringe cylinder ( 15 , 26 ) with the corresponding one Serve housing ( 16 ) fixable as a controller ( 2 ) and are suitable to control at least one actuator ( 7 ), preferably using at least one comparator and a directional discriminator. 4. Bausatz nach mindestens einem der Ansprüche 1-3, dadurch gekennzeichnet, daß ein bevorzugter Schleif- oder Steckkontakt und/oder eine induktive Kontaktierung o. dgl. (17) geeignet ist/sind, die Verbindung zum Stellglied (7) herzustellen, das in bevorzugter Ausführungsform die Regelelektronik eines Elektromotors darstellt, der über eine optimierte Spritzenhalte- (18) bzw. -führungsvorrichtung (19) mittels einer bevorzugten elastischen Welle (20) die vorprogrammierte Medikamentenapplikation ermöglicht.4. Kit according to at least one of claims 1-3, characterized in that a preferred sliding or plug contact and / or an inductive contact or the like. ( 17 ) is / are suitable to make the connection to the actuator ( 7 ), the represents in a preferred embodiment the control electronics of an electric motor, which enables the pre-programmed medication application via an optimized syringe holder ( 18 ) or guide device ( 19 ) by means of a preferred elastic shaft ( 20 ). 5. Bausatz nach mindestens einem der Ansprüche 1-4, dadurch gekennzeichnet, daß der Kolbenverschub geeignet ist, pneumatisch mit darauf abgestimmtem Stellglied und geeigneter Spritzenhalte- bzw. -führungsvorrichtung zu erfolgen.5. Kit according to at least one of claims 1-4, characterized, that the piston displacement is suitable, pneumatically with matching actuator and more suitable Syringe holding or guiding device to take place. 6. Bausatz nach mindestens einem der Ansprüche 1-5, dadurch gekennzeichnet, daß bei Mehrfachinjektionen bevorzugt ein überge­ ordneter Regler geeignet ist, die Einzelinjektionen nach der erfolgten Programmierung zu steuern, wobei bevorzugt jeder Injektionsspritze (1) ein separater Antrieb mit separatem Stellglied zugeordnet ist.6. Kit according to at least one of claims 1-5, characterized in that in the case of multiple injections, a superordinate controller is preferably suitable for controlling the individual injections after the programming has been carried out, with each injection syringe ( 1 ) preferably being assigned a separate drive with a separate actuator . 7. Bausatz nach mindestens einem der Ansprüche 1-6, dadurch gekennzeichnet, daß der Regler geeignet ist, bevorzugt über mindestens ein an der Kolbenstange bevorzugt federgelagertes Reibrad, ggf. mit Umlenkung und Winkelbestimmung, mechanisch und/oder mittels sonstiger elektronischer Code-Meßverfahren, den longitudinalen Kolbenverschub und damit das injizierte Medikamentenvolumen zu bestimmen.7. Kit according to at least one of claims 1-6, characterized,  that the controller is suitable, preferably over at least a preferably spring-loaded on the piston rod Friction wheel, possibly with deflection and angle determination, mechanically and / or by means of other electronic Code measuring method, the longitudinal piston displacement and thus the injected drug volume determine. 8. Bausatz nach mindestens einem der Ansprüche 1-7, dadurch gekennzeichnet, daß die Regelelektronik bevorzugt in einem dem Spritzenzylinder (15), bevorzugt im Bereich der Fingerstützen (26), adaptierten und sicher fixierten Gehäuse (16) integriert und geeignet ist, Longitudinalbewegungen der Kolbenstange (11) sicher zu ermitteln, wobei die bevorzugte Stromversorgung (22) z. B. in Form mindestens einer Knopfzelle einfach zu wechseln ist.8. Kit according to at least one of claims 1-7, characterized in that the control electronics are preferably integrated in a syringe barrel ( 15 ), preferably in the region of the finger supports ( 26 ), adapted and securely fixed housing ( 16 ), suitable for longitudinal movements determine the piston rod ( 11 ) safely, the preferred power supply ( 22 ) z. B. is easy to change in the form of at least one button cell. 9. Bausatz nach mindestens einem der Ansprüche 1-8, dadurch gekennzeichnet, daß der jeweilige Durchlichtmaßstab (9) in der erforderlichen Größe aus transparentem Kunststoff mit der/den erforderlichen Strichmarkierung/en (32) zur Verfügung steht, die (32) wiederum mit einer bevorzugten Abtastplatte (8) korrespondiert/en.9. Kit according to at least one of claims 1-8, characterized in that the respective transmitted light scale ( 9 ) is available in the required size made of transparent plastic with the required line marking (s) ( 32 ), which ( 32 ) in turn with corresponds to a preferred scanning plate ( 8 ). 10. Bausatz nach mindestens einem der Ansprüche 1-9, dadurch gekennzeichnet, daß die für Regelzwecke benutzten Spritzen (1) mit auf den Kolbenfortsätzen (11) herstellungsmäßig aufgebrachten Strichmaßstäben (9) lieferbar sind, bzw. daß mindestens ein Kolbensegment geeignet ist, als Strichmaßstab zu dienen. 10. Kit according to at least one of claims 1-9, characterized in that the syringes used for control purposes ( 1 ) with line scales ( 9 ) applied to the piston extensions ( 11 ) are available for production, or that at least one piston segment is suitable as Line scale to serve. 11. Bausatz zur gesteuerten Medikamentenapplikation, dadurch gekennzeichnet, daß ein Durchlichtmaßstab mit bevorzugt mehreren gegeneinander versetzten Teilungsstrecken und bevorzugt minimierter Teilungsperiode beim bevorzugten LED-Lichtdurchtritt in eine gegen bevorzugt Fremd- und/oder Streulicht abgeschirmte Kammer mit bevorzugt einem einzigen auf die Teilungsperiode abgestimmten Lichtdurchlaß einer Trennplatte (modifizierte Abtastplatte) o. dgl. geeignet ist, mindestens ein Photoelement so zu aktivieren, daß dieses wiederum geeignet ist, eine aktuelle bevorzugt heruntergeteilte Frequenz mindestens eines Schwingquarzes zu erfassen und ggf. mit dem bevorzugt gleichen und bevorzugt gleich heruntergeteilten Schwingquarz einer bevorzugt programmierbaren Echtzeituhr zu vergleichen, um Abweichungen im so gestalteten und zusätzlich programmierten Regler dem Stellglied zuzuleiten, wobei alternativ anstelle des bevorzugten photoelektrischen Meßprinzips geeignete Kontakte konzipierbar sind.11. Kit for controlled medication application, characterized, that a transmitted light scale with preferably several offset sections and preferably minimized division period in the preferred LED light passage in a preferred against foreign and / or Chamber shielded from stray light with preference one matched to the division period Light transmission of a partition plate (modified Scanning plate) or the like is suitable, at least one Activate the photo element so that this in turn is suitable, a current preferably divided Frequency of at least one quartz crystal and optionally with the same and preferred equally divided quartz crystal one preferred programmable real time clock to compare Deviations in the so designed and additional to feed the programmed controller to the actuator, whereby alternatively, instead of the preferred photoelectric Measuring principles suitable contacts are conceivable. 12. Bausatz nach mindestens einem der Ansprüche 1-11, dadurch gekennzeichnet, daß bevorzugt Uhrenschwingquarze mit einer üblichen Frequenz Verwendung finden, die über Frequenzteiler synchron auf einen definierten Wert heruntergeteilt werden.12. Kit according to at least one of claims 1-11, characterized, that preferred watch quartz crystals with a usual Find frequency use using frequency dividers divided down synchronously to a defined value will. 13. Bausatz nach mindestens einem der Ansprüche 1-12, dadurch gekennzeichnet, daß aus Sicherheitsgründen wesentliche Steuerungs­ elemente und die Stromversorgung in doppelter Ausführung und im Stand-by-Betrieb vorhanden sind.13. Kit according to at least one of claims 1-12, characterized, that essential control for security reasons elements and the power supply in double Execution and are available in stand-by mode. 14. Bausatz nach mindestens einem der Ansprüche 1-13, dadurch gekennzeichnet, daß der Regler bevorzugt bei einer Vorschubgewinde­ -stange bevorzugt als deren Winkel- bzw. Umdrehungsmeß­ vorrichtung konzipiert ist.14. Kit according to at least one of claims 1-13,  characterized, that the controller prefers a feed thread rod preferred as their angle or revolution measurement device is designed. 15. Bausatz nach mindestens einem der Ansprüche 1-14, dadurch gekennzeichnet, daß der Gewindestab aus Anspruch 14. bevorzugt ein Feinstgewinde aufweist und bevorzugt den Regler mitnimmt, wobei eine dem Verfahrweg ausreichende Länge gewährleistet ist.15. Kit according to at least one of claims 1-14, characterized, that the threaded rod from claim 14 preferably a Has very fine thread and preferably the controller takes along, with a length sufficient for the travel is guaranteed. 16. Bausatz nach mindestens einem der Ansprüche 1-15, dadurch gekennzeichnet, daß der Gewindestab aus Anspruch 14. eine bevorzugte Längsnut aufweist, in die ein Mitnehmer eines bevorzugt stationären Reglers einzugreifen in der Lage ist, der mit entsprechender Zusatzelektronik ausgestattet geeignet ist, Stellgliedfunktion zusätzlich zu übernehmen.16. Kit according to at least one of claims 1-15, characterized, that the threaded rod of claim 14 is preferred Has longitudinal groove into which a driver a able to intervene preferably stationary controller is that with appropriate additional electronics is suitable, actuator function to take over in addition. 17. Bausatz nach mindestens einem der Ansprüche 1-16, dadurch gekennzeichnet, daß der Regler und/oder das Stellglied geeignet ist/sind, über bevorzugt ein ortszuständiges Zeitfunksignal mittels geeigneter Antenne angesteuert zu werden, das darüber hinaus auch als Echtzeituhr dient.17. Kit according to at least one of claims 1-16, characterized, that the controller and / or the actuator is suitable is / are, preferably via a local authority Time radio signal controlled by a suitable antenna to become a real-time clock serves.
DE19643813A 1996-09-26 1996-10-30 Kit for controlled injection of drugs Withdrawn DE19643813A1 (en)

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DE19643813A DE19643813A1 (en) 1996-09-26 1996-10-30 Kit for controlled injection of drugs

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Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002028456A1 (en) * 2000-10-05 2002-04-11 Novo Nordisk A/S A medication delivery system with improved dose accuracy
DE10154954A1 (en) * 2001-11-11 2003-06-05 Said Mansouri Anesthesia syringe is fitted with control unit for injection process
WO2004009163A1 (en) * 2002-07-24 2004-01-29 Deka Products Limited Partnership Optical displacement sensor for infusion devices
FR2848860A1 (en) * 2002-12-20 2004-06-25 Sedat Medical injection instrument e.g. for contrast fluid has syringe operated by handle in two articulated sections for single-handed operation and controlled pressure
JP2007167222A (en) * 2005-12-20 2007-07-05 Japan Servo Co Ltd Syringe pump device
WO2008040479A1 (en) * 2006-10-07 2008-04-10 Sanofi-Aventis Deutschland Gmbh Optical determination of the position of the stopper in glass ampoules
CN100415314C (en) * 2006-03-17 2008-09-03 浙江浙大医学仪器有限公司 Alarming transmission device for syring inaccurate installation
EP2065064A1 (en) * 2007-11-29 2009-06-03 Valtronic Technologies (Suisse) SA Pen injector for medication
US7704231B2 (en) 2004-02-18 2010-04-27 Ares Trading S.A. Hand-held electronically controlled injection device for injecting liquid medications
US7717879B2 (en) 2004-02-03 2010-05-18 Smjm Inject Gmbh Anesthetic syringe
WO2015143058A1 (en) * 2014-03-21 2015-09-24 Osprey Medical, Inc. Syringe with optical system for monitoring the position of the plunger rod
US9999718B2 (en) 2012-08-28 2018-06-19 Osprey Medical, Inc. Volume monitoring device utilizing light-based systems
US10413677B2 (en) 2012-08-28 2019-09-17 Osprey Medical, Inc. Volume monitoring device
CN110711293A (en) * 2018-07-13 2020-01-21 西诺医药有限责任公司 High precision syringe with detachable pump unit
US11116892B2 (en) 2012-08-28 2021-09-14 Osprey Medical, Inc. Medium injection diversion and measurement
US11135375B2 (en) 2012-08-28 2021-10-05 Osprey Medical, Inc. Volume monitoring systems
US11499841B2 (en) 2019-04-12 2022-11-15 Osprey Medical, Inc. Energy-efficient position determining with multiple sensors
US11951291B2 (en) 2018-04-19 2024-04-09 Eli Lilly And Company Status sensing system for injection device

Cited By (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7500959B2 (en) 2000-10-05 2009-03-10 Novo Nordisk A/S Medication delivery system with improved dose accuracy
WO2002028456A1 (en) * 2000-10-05 2002-04-11 Novo Nordisk A/S A medication delivery system with improved dose accuracy
DE10154954A1 (en) * 2001-11-11 2003-06-05 Said Mansouri Anesthesia syringe is fitted with control unit for injection process
JP2011020003A (en) * 2002-07-24 2011-02-03 Deka Products Lp Optical displacement sensor for infusion device
WO2004009163A1 (en) * 2002-07-24 2004-01-29 Deka Products Limited Partnership Optical displacement sensor for infusion devices
US8552361B2 (en) 2002-07-24 2013-10-08 Deka Products Limited Partnership Optical displacement sensor for infusion devices
JP2005533568A (en) * 2002-07-24 2005-11-10 デカ・プロダクツ・リミテッド・パートナーシップ Optical deflection sensor for injection devices.
CN1671432B (en) * 2002-07-24 2010-05-12 德卡产品有限公司 Optical Displacement Sensors for Infusion Devices
AU2003256696B2 (en) * 2002-07-24 2008-12-11 Deka Products Limited Partnership Optical displacement sensor for infusion devices
US7498563B2 (en) 2002-07-24 2009-03-03 Deka Products Limited Partnership Optical displacement sensor for infusion devices
FR2848860A1 (en) * 2002-12-20 2004-06-25 Sedat Medical injection instrument e.g. for contrast fluid has syringe operated by handle in two articulated sections for single-handed operation and controlled pressure
US7717879B2 (en) 2004-02-03 2010-05-18 Smjm Inject Gmbh Anesthetic syringe
US7704231B2 (en) 2004-02-18 2010-04-27 Ares Trading S.A. Hand-held electronically controlled injection device for injecting liquid medications
US8376985B2 (en) 2004-02-18 2013-02-19 Ares Trading S.A. Hand-held electronically controlled injection device for injecting liquid medications
US7967784B2 (en) 2004-02-18 2011-06-28 Ares Trading S.A. Hand-held electronically controlled injection device for injecting liquid medications
JP2007167222A (en) * 2005-12-20 2007-07-05 Japan Servo Co Ltd Syringe pump device
CN100415314C (en) * 2006-03-17 2008-09-03 浙江浙大医学仪器有限公司 Alarming transmission device for syring inaccurate installation
CN101522239B (en) * 2006-10-07 2013-04-24 塞诺菲-安万特德国有限公司 Optical determination of the position of a stopper in a glass cartridge
CN101522239A (en) * 2006-10-07 2009-09-02 塞诺菲-安万特德国有限公司 Optical determination of the position of the stopper in glass ampoules
WO2008040479A1 (en) * 2006-10-07 2008-04-10 Sanofi-Aventis Deutschland Gmbh Optical determination of the position of the stopper in glass ampoules
EP2076300B2 (en) † 2006-10-07 2016-04-13 Sanofi-Aventis Deutschland GmbH Optical determination of the position of the stopper in glass ampoules
US10712148B2 (en) 2006-10-07 2020-07-14 Sanofi-Aventis Deutschland Gmbh Optical determination of the position of the stopper in glass ampoules
EP2065064A1 (en) * 2007-11-29 2009-06-03 Valtronic Technologies (Suisse) SA Pen injector for medication
US9999718B2 (en) 2012-08-28 2018-06-19 Osprey Medical, Inc. Volume monitoring device utilizing light-based systems
US10413677B2 (en) 2012-08-28 2019-09-17 Osprey Medical, Inc. Volume monitoring device
US11116892B2 (en) 2012-08-28 2021-09-14 Osprey Medical, Inc. Medium injection diversion and measurement
US11135375B2 (en) 2012-08-28 2021-10-05 Osprey Medical, Inc. Volume monitoring systems
US11219719B2 (en) 2012-08-28 2022-01-11 Osprey Medical, Inc. Volume monitoring systems
WO2015143058A1 (en) * 2014-03-21 2015-09-24 Osprey Medical, Inc. Syringe with optical system for monitoring the position of the plunger rod
US11951291B2 (en) 2018-04-19 2024-04-09 Eli Lilly And Company Status sensing system for injection device
CN110711293A (en) * 2018-07-13 2020-01-21 西诺医药有限责任公司 High precision syringe with detachable pump unit
US11499841B2 (en) 2019-04-12 2022-11-15 Osprey Medical, Inc. Energy-efficient position determining with multiple sensors

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