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DE122009000006I1 - Pharmazeutische kombination von ethinylestradiol und drospirenone als empfängnisverhütendes mittel - Google Patents

Pharmazeutische kombination von ethinylestradiol und drospirenone als empfängnisverhütendes mittel

Info

Publication number
DE122009000006I1
DE122009000006I1 DE122009000006C DE122009000006C DE122009000006I1 DE 122009000006 I1 DE122009000006 I1 DE 122009000006I1 DE 122009000006 C DE122009000006 C DE 122009000006C DE 122009000006 C DE122009000006 C DE 122009000006C DE 122009000006 I1 DE122009000006 I1 DE 122009000006I1
Authority
DE
Germany
Prior art keywords
drospirenone
ethinylestradiol
consumer
pharmaceutical combination
preventive agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE122009000006C
Other languages
English (en)
Other versions
DE122009000006I2 (de
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Bayer Schering Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26153359&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE122009000006(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Schering Pharma AG filed Critical Bayer Schering Pharma AG
Publication of DE122009000006I1 publication Critical patent/DE122009000006I1/de
Publication of DE122009000006I2 publication Critical patent/DE122009000006I2/de
Active legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE200912000006 1999-08-31 2000-08-31 Pharmazeutische kombination von ethinylestradiol und drospirenone als empfangnisverhutendes mittel. Active DE122009000006I2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38627499A 1999-08-31 1999-08-31
EP99202826 1999-08-31
PCT/IB2000/001213 WO2001015701A1 (en) 1999-08-31 2000-08-31 Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptive

Publications (2)

Publication Number Publication Date
DE122009000006I1 true DE122009000006I1 (de) 2009-05-07
DE122009000006I2 DE122009000006I2 (de) 2012-03-22

Family

ID=26153359

Family Applications (5)

Application Number Title Priority Date Filing Date
DE200912000006 Active DE122009000006I2 (de) 1999-08-31 2000-08-31 Pharmazeutische kombination von ethinylestradiol und drospirenone als empfangnisverhutendes mittel.
DE60006692T Expired - Lifetime DE60006692T2 (de) 1999-08-31 2000-08-31 Pharmazeutische kombination von ethinylestradiol und drospirenone als empfängnisverhütendes mittel
DE200912000007 Active DE122009000007I2 (de) 1999-08-31 2000-08-31 Pharmazeutische kombination von ethinylestradiol und drospirenone als empfangnisverhutendes mittel.
DE60041421T Expired - Lifetime DE60041421D1 (de) 1999-08-31 2000-08-31 Pharmazeutische Kombination von Ethinylestradiol und Drospirenon als empfängnisverhütendes Mittel
DE60042089T Expired - Lifetime DE60042089D1 (de) 1999-08-31 2000-08-31 Pharmazeutische Kombination von Ethinylestradiol und Drospirenon als empfängnisverhütendes Mittel

Family Applications After (4)

Application Number Title Priority Date Filing Date
DE60006692T Expired - Lifetime DE60006692T2 (de) 1999-08-31 2000-08-31 Pharmazeutische kombination von ethinylestradiol und drospirenone als empfängnisverhütendes mittel
DE200912000007 Active DE122009000007I2 (de) 1999-08-31 2000-08-31 Pharmazeutische kombination von ethinylestradiol und drospirenone als empfangnisverhutendes mittel.
DE60041421T Expired - Lifetime DE60041421D1 (de) 1999-08-31 2000-08-31 Pharmazeutische Kombination von Ethinylestradiol und Drospirenon als empfängnisverhütendes Mittel
DE60042089T Expired - Lifetime DE60042089D1 (de) 1999-08-31 2000-08-31 Pharmazeutische Kombination von Ethinylestradiol und Drospirenon als empfängnisverhütendes Mittel

Country Status (26)

Country Link
EP (4) EP1380301B1 (de)
JP (2) JP4354667B2 (de)
KR (2) KR101019361B1 (de)
AT (3) ATE254464T1 (de)
AU (4) AU780330B2 (de)
BG (1) BG66114B1 (de)
BR (1) BR0014159A (de)
CY (3) CY1108990T1 (de)
CZ (1) CZ300514B6 (de)
DE (5) DE122009000006I2 (de)
DK (3) DK1598069T3 (de)
EE (1) EE05128B1 (de)
ES (3) ES2211580T3 (de)
HK (1) HK1047247B (de)
HR (1) HRP20070188B1 (de)
HU (1) HU227207B1 (de)
IL (1) IL148339A0 (de)
ME (2) MEP36008A (de)
NO (1) NO326860B1 (de)
NZ (1) NZ517845A (de)
PL (1) PL199028B1 (de)
PT (3) PT1598069E (de)
RS (3) RS50262B (de)
SI (3) SI1214076T1 (de)
TW (1) TWI276436B (de)
WO (1) WO2001015701A1 (de)

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KR101019361B1 (ko) * 1999-08-31 2011-03-07 바이엘 쉐링 파마 악티엔게젤샤프트 피임약으로서의 사용을 위한 에티닐에스트라디올과드로스피렌온의 약학적 조합
RS52149B (sr) * 2000-01-18 2012-08-31 Bayer Schering Pharma Aktiengesellschaft Farmaceutska kombinacija mikronizovanog drospirenona i estrogena za terapiju zamene hormona
JO2334B1 (en) * 2000-01-18 2006-06-28 باير شيرنغ فارما اكتنجيسيلشافت Drospirenone for hormone replacement therapy
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EP1216713A1 (de) * 2000-12-20 2002-06-26 Schering Aktiengesellschaft Zusammensetzungen von Estrogen-Zyklodextrin Komplexe
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US7786101B2 (en) 2002-11-05 2010-08-31 Bayer Schering Pharma Ag Cardiovascular protection using anti-aldosteronic progestins
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WO2009112232A2 (en) * 2008-03-10 2009-09-17 Vladimir Hanes New drospirenone/17beta-estradiol regimen, pharmaceutical combination product and kit for performing this regimen
TW200942242A (en) * 2008-03-10 2009-10-16 Rolf Schurmann New drospirenone/17β-estradiol regimen, pharmaceutical combination product and kit for performing this regimen
WO2009138224A1 (en) * 2008-05-14 2009-11-19 Helm Ag Pharmaceutical composition comprising drospirenone
DE102008037025C5 (de) 2008-08-08 2016-07-07 Jesalis Pharma Gmbh Verfahren zur Herstellung kristalliner Wirkstoff-Mikropartikel bzw. einer Wirkstoffpartikel-Festkörperform
WO2010094623A1 (en) 2009-02-18 2010-08-26 Bayer Schering Pharma Aktiengesellschaft Formulation comprising drospirenone for subcutaneous or intramuscular administration
UY32836A (es) 2009-08-12 2011-03-31 Bayer Schering Pharma Ag Partículas estabilizadas que comprenden 5-metil-(6s)-tetrahidrofolato
CN102985070A (zh) * 2010-04-15 2013-03-20 拜耳知识产权有限责任公司 用于hrt的极低剂量的固体口服剂型
AR081670A1 (es) 2010-06-29 2012-10-10 Leon Farma Sa Lab Composicion farmaceutica que comprende drospirenona y kit anticonceptivo
US11351122B1 (en) 2010-07-28 2022-06-07 Laboratorios Leon Farma Sa Synthetic progestogens and pharmaceutical compositions comprising the same
US10849857B2 (en) 2010-07-28 2020-12-01 Laboratorios Leon Farma Sa Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same
US9603860B2 (en) 2010-07-28 2017-03-28 Laboratorios Leon Farma Sa Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same
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RS52149B (sr) * 2000-01-18 2012-08-31 Bayer Schering Pharma Aktiengesellschaft Farmaceutska kombinacija mikronizovanog drospirenona i estrogena za terapiju zamene hormona

Also Published As

Publication number Publication date
BR0014159A (pt) 2002-05-07
KR20070067248A (ko) 2007-06-27
ATE420648T1 (de) 2009-01-15
NO20020801L (no) 2002-04-26
AU2005202046A1 (en) 2005-06-09
DK1214076T3 (da) 2004-02-23
EP2044941A1 (de) 2009-04-08
DE122009000006I2 (de) 2012-03-22
HRP20070188B1 (hr) 2015-06-19
PL199028B1 (pl) 2008-08-29
JP4354667B2 (ja) 2009-10-28
EP1598069A2 (de) 2005-11-23
EP1598069A3 (de) 2006-04-05
HK1082432A1 (en) 2006-06-09
IL148339A0 (en) 2002-09-12
EP1214076A1 (de) 2002-06-19
NO20020801D0 (no) 2002-02-19
HRP20070188A2 (en) 2007-07-31
DE60006692T2 (de) 2004-09-23
HUP0202500A3 (en) 2004-04-28
EP1214076B1 (de) 2003-11-19
EE200200110A (et) 2003-06-16
HU227207B1 (en) 2010-11-29
JP2003508441A (ja) 2003-03-04
EP1380301B1 (de) 2009-01-14
PT1598069E (pt) 2009-07-20
AU780330B2 (en) 2005-03-17
DE60042089D1 (de) 2009-06-04
DK1598069T3 (da) 2009-07-06
ES2319750T3 (es) 2009-05-12
JP2009143959A (ja) 2009-07-02
AU2010226924A1 (en) 2010-10-28
WO2001015701A1 (en) 2001-03-08
KR20020040798A (ko) 2002-05-30
ES2325589T3 (es) 2009-09-09
HK1061968A1 (en) 2004-10-15
CZ2002615A3 (cs) 2002-08-14
PT1214076E (pt) 2004-04-30
KR100857344B1 (ko) 2008-09-05
ME00329B (me) 2011-05-10
TWI276436B (en) 2007-03-21
RS50262B (sr) 2009-07-15
ATE429231T1 (de) 2009-05-15
SI1214076T1 (en) 2004-06-30
DE60006692D1 (de) 2003-12-24
BG66114B1 (bg) 2011-05-31
HK1047247B (en) 2004-07-23
NO326860B1 (no) 2009-03-02
NZ517845A (en) 2004-12-24
CY1108990T1 (el) 2014-02-12
AU2009200247B2 (en) 2010-07-01
CZ300514B6 (cs) 2009-06-03
DK1380301T3 (da) 2009-04-20
AU2005202046B9 (en) 2008-12-11
ATE254464T1 (de) 2003-12-15
ES2211580T3 (es) 2004-07-16
RS20090134A (sr) 2009-11-10
CY2009015I1 (el) 2014-02-12
EP1598069B1 (de) 2009-04-22
SI1598069T1 (sl) 2009-10-31
DE60041421D1 (de) 2009-03-05
AU6589500A (en) 2001-03-26
CY1109252T1 (el) 2014-07-02
PT1380301E (pt) 2009-03-30
RS50262B2 (sr) 2018-10-31
AU2009200247A1 (en) 2009-02-19
EE05128B1 (et) 2009-02-16
DE122009000007I1 (de) 2009-05-07
HUP0202500A2 (en) 2002-10-28
HK1047247A1 (en) 2003-02-14
AU2005202046B2 (en) 2008-11-20
KR101019361B1 (ko) 2011-03-07
DE122009000007I2 (de) 2011-07-21
SI1380301T1 (sl) 2009-06-30
CY2009015I2 (el) 2014-02-12
EP1380301A1 (de) 2004-01-14
PL354406A1 (pl) 2004-01-12
YU14502A (sh) 2006-01-16
MEP36008A (hr) 2011-02-10

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