[go: up one dir, main page]

DE122006000018I2 - 19-Nor-Vitamin-D-Derivate. - Google Patents

19-Nor-Vitamin-D-Derivate.

Info

Publication number
DE122006000018I2
DE122006000018I2 DE122006000018C DE122006000018C DE122006000018I2 DE 122006000018 I2 DE122006000018 I2 DE 122006000018I2 DE 122006000018 C DE122006000018 C DE 122006000018C DE 122006000018 C DE122006000018 C DE 122006000018C DE 122006000018 I2 DE122006000018 I2 DE 122006000018I2
Authority
DE
Germany
Prior art keywords
vitamin
undifferentiated cells
cells
malignant
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE122006000018C
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26982778&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE122006000018(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/481,354 external-priority patent/US5237110A/en
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of DE122006000018I2 publication Critical patent/DE122006000018I2/de
Active legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE122006000018C 1989-03-09 1990-03-09 19-Nor-Vitamin-D-Derivate. Active DE122006000018I2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32103089A 1989-03-09 1989-03-09
US07/481,354 US5237110A (en) 1989-03-09 1990-02-16 19-nor-vitamin d compounds

Publications (1)

Publication Number Publication Date
DE122006000018I2 true DE122006000018I2 (de) 2008-05-08

Family

ID=26982778

Family Applications (3)

Application Number Title Priority Date Filing Date
DE1990606052 Pending DE122006000018I1 (de) 1989-03-09 1990-03-09 19-Nor-Vitamin-D-Derivate
DE122006000018C Active DE122006000018I2 (de) 1989-03-09 1990-03-09 19-Nor-Vitamin-D-Derivate.
DE90302521T Expired - Lifetime DE69006052T2 (de) 1989-03-09 1990-03-09 19-Nor-Vitamin-D-Derivate.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE1990606052 Pending DE122006000018I1 (de) 1989-03-09 1990-03-09 19-Nor-Vitamin-D-Derivate

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE90302521T Expired - Lifetime DE69006052T2 (de) 1989-03-09 1990-03-09 19-Nor-Vitamin-D-Derivate.

Country Status (8)

Country Link
EP (1) EP0387077B1 (de)
CN (1) CN1033857C (de)
AT (1) ATE100447T1 (de)
DE (3) DE122006000018I1 (de)
ES (1) ES2062334T3 (de)
IE (1) IE64526B1 (de)
NL (1) NL300228I1 (de)
NZ (1) NZ232734A (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2229921B (en) * 1989-04-05 1992-12-16 Chugai Pharmaceutical Co Ltd Treatment for hyperparathyroidism with use of vitamin d derivatives
US5459136A (en) * 1990-08-24 1995-10-17 Wisconsin Alumni Research Foundation Methods using vitamin D compounds for improvement of skin conditions
AU649057B2 (en) * 1990-08-24 1994-05-12 Wisconsin Alumni Research Foundation Methods and compositions containing vitamin D compounds for improvement of skin conditions
ATE173401T1 (de) * 1990-09-07 1998-12-15 Wisconsin Alumni Res Found Neue verwendung von 1-alpha-hydroxylierten-19-nor-vitamin-d-verbind ngen zur behandlung von psoriasis
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
US5086191A (en) * 1991-05-28 1992-02-04 Wisconsin Alumni Research Foundation Intermediates for the synthesis of 19-nor vitamin D compounds
ATE143007T1 (de) * 1991-07-05 1996-10-15 Duphar Int Res Vitamin-d derivat, verfahren zu dessen herstellung sowie zwischenprodukte dafür
CA2129120A1 (en) * 1992-01-29 1993-08-05 Joyce C. Knutson 1.alpha.-hydroxy-24-epi-vitamin d4
DE4220757A1 (de) * 1992-06-24 1994-01-05 Schering Ag Derivate in der Vitamin D-Reihe mit Modifikationen in der 20-Position, Verfahren zu ihrer Herstellung, Zwischenprodukte für dieses Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
AU666563B2 (en) * 1992-08-07 1996-02-15 Wisconsin Alumni Research Foundation Preparation of 19-nor-vitamin D compounds
CA2096105A1 (en) * 1992-10-07 1994-04-08 Enrico Giuseppe Baggiolini (Deceased) Vitamin d3 fluorinated analogs
US5753638A (en) * 1992-10-07 1998-05-19 Hoffmann-La Roche Inc. Method of treating hyperproliferative skin disease with Vitamin D3 fluorinated analogs
TW267161B (de) * 1992-11-20 1996-01-01 Hoffmann La Roche
DE69400495T2 (de) * 1993-04-05 1997-04-30 Wisconsin Alumni Res Found 19-Nor-vitamin-D3-Verbindung mit einem Substituent an die 2. Stelle
US5449668A (en) * 1993-06-04 1995-09-12 Duphar International Research B.V. Vitamin D compounds and method of preparing these compounds
ES2209327T3 (es) * 1993-07-09 2004-06-16 Laboratoire Theramex Nuevos analogos estructurales de la vitamina d.
DE69503394T2 (de) * 1994-01-20 1999-03-11 Duphar International Research B.V., Weesp Vitamin-D-Derivate und Verfahren zu deren Herstellung
BR9509739A (pt) * 1994-11-21 1997-10-21 Wisconsin Alumni Res Found Compostos 18,19-dinor-vitamina d
DE69508895T2 (de) * 1994-12-14 1999-10-21 Duphar International Research B.V., Weesp Vitamin-D-Derivate und Verfahren zur Herstellung dieser Verbindungen
US5597815A (en) * 1995-07-13 1997-01-28 Wisconsin Alumni Research Foundation Prevention of hyperphosphatemia in kidney disorder patients
EP0870503B9 (de) * 1995-12-28 2006-06-28 Chugai Seiyaku Kabushiki Kaisha Verwendung von Vitamin D Derivaten zur Herstellung eines Medikaments zur Behandlung von BÖSARTIGEN TUMORMETASTASE
US6869940B2 (en) 1995-12-28 2005-03-22 Chugai Seiyaku Kabushiki Kaisha Malignant tumor metastasis inhibitors
US5891865A (en) * 1996-10-04 1999-04-06 Wisconsin Alumni Research Foundation Treatment of arthritic disease induced by infectious agents
US6306844B1 (en) 1997-03-17 2001-10-23 Wisconsin Alumni Research Foundation Use of 2α-methyl-19-nor-20(S)-1α, 25-dihydroxyvitamin D3 to increase bone strength
US5945410A (en) * 1997-03-17 1999-08-31 Wisconsin Alumni Research Foundation 2-alkyl-19-nor-vitamin D compounds
US6392071B1 (en) 1997-03-17 2002-05-21 Wisconsin Alumni: Research Foundation 26,27-homologated-20-EPI-2-alkylidene-19-nor-vitamin D compounds
US6316642B1 (en) 1997-03-17 2001-11-13 Wisconsin Alumni Research Foundation 26,27-Homologated-20-EPI-2alkyl-19-nor-vitamin D compounds
US5843928A (en) * 1997-03-17 1998-12-01 Wisconsin Alumni Research Foundation 2-alkylidene-19-nor-vitamin D compounds
JP3276375B2 (ja) * 1997-05-23 2002-04-22 バジリア ファルマスーチカ アーゲー シクロヘキサンジオール誘導体
US5939406A (en) * 1997-07-21 1999-08-17 Wisconsin Alumni Research Foundation 18-substituted-19-nor-vitamin D compounds
US6114317A (en) 1998-05-21 2000-09-05 Wisconsin Alumni Research Foundation Method of locking 1α-OH of vitamin D compounds in axial orientation
AU2001265272B2 (en) 2000-05-31 2006-08-17 Wisconsin Alumni Research Foundation 2-ethyl and 2-ethylidene-19-nor-vitamin d compounds
US7241747B2 (en) 2003-04-10 2007-07-10 Wisconsin Alumni Research Foundation 2-propylidene-19-nor-vitamin D compounds
US6894037B2 (en) 2003-07-03 2005-05-17 Wisconsin Alumni Research Foundation 2-methylene-19-nor-20(S)-25-methyl-1α-hydroxycalciferol and its uses
US7713951B2 (en) 2004-04-09 2010-05-11 Wisconsin Alumni Research Foundation 2-alkylidene-18,19-dinor-vitamin D compounds
CA2612604A1 (en) * 2005-07-18 2007-01-25 Anchel Schwartz Purification of paricalcitol
EP2010483A2 (de) 2006-04-05 2009-01-07 Wisconsin Alumni Research Foundation 1.alpha.-hydroxy-2-(3'-hydroxypropyliden)-19-nor-vitamin-d-verbindungen sowie verfahren zu ihrer herstellung und verwendung
US8377913B2 (en) * 2007-11-20 2013-02-19 Abbvie Inc. Vitamin D receptor activators and methods of making
US7491712B1 (en) 2007-12-10 2009-02-17 Formosa Laboratories, Inc. Process for preparation of paricalcitol and intermediates thereof
WO2010009879A2 (en) 2008-07-22 2010-01-28 Azad Pharmaceutical Ingredients Ag Methods for producing paricalcitol
PL216135B1 (pl) 2009-08-07 2014-03-31 Inst Farmaceutyczny Nowe syntony i ich zastosowanie do otrzymywania pochodnych 19-nor witamin D
EP2545940A1 (de) 2011-07-14 2013-01-16 hameln rds gmbh Parenterale Zusammensetzungen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4448726A (en) * 1983-05-11 1984-05-15 Wisconsin Alumni Research Foundation Ring A- and triene-modified vitamin D compounds
NL8520009A (nl) * 1984-01-30 1985-12-02 Wisconsin Alumni Res Found 1alfa.25-dihydroxy-22z-dehydrovitamine d verbinding.
US4555364A (en) * 1984-11-01 1985-11-26 Wisconsin Alumni Research Foundation Method for preparing 1-hydroxyvitamin D compounds
CA1314872C (en) * 1986-04-25 1993-03-23 Toshio Nishizawa Fluorine derivatives of vitamin d _and process for producing the same

Also Published As

Publication number Publication date
ATE100447T1 (de) 1994-02-15
ES2062334T3 (es) 1994-12-16
IE900840L (en) 1990-09-09
EP0387077A1 (de) 1990-09-12
IE64526B1 (en) 1995-08-09
CN1033857C (zh) 1997-01-22
DE122006000018I1 (de) 2006-06-29
EP0387077B1 (de) 1994-01-19
DE69006052D1 (de) 1994-03-03
NZ232734A (en) 1991-11-26
DE69006052T2 (de) 1994-05-05
NL300228I1 (nl) 2006-06-01
CN1046155A (zh) 1990-10-17

Similar Documents

Publication Publication Date Title
ATE100447T1 (de) 19-nor-vitamin-d-derivate.
HU896762D0 (en) Process for preparation of pyrimidine-derivatives and for manufacturing of pharmaceutical compositions containing these compounds
AU549481B2 (en) Hair growing agent
YU29099A (sh) Derivati 2-(purin-9-il)-tetrahidrofuran-3,4-diola
GR3019450T3 (en) Azaheterocyclylmethyl-chromans as agents for the treatment of diseases of the central nervous system
AP2000001881A0 (en) 2-(Purine-9-YL)-tetrahydrofuran-3,4 4-diol derivatives.
EP0363415A4 (en) Compounds for the treatment of alzheimer's disease
BG104729A (en) 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
ATE90342T1 (de) 1-hydroxyvitamin d2-epimer und dessen derivate.
DK0412554T3 (da) Sustained-release-præparat til administration i hjernen
IL68456A (en) Pharmaceutical compositions comprising perfluoro-substituted compounds as vehicles
EP0328634A4 (en) Pharmaceutical compositions for the treatment of psoriasis
ATE67495T1 (de) 4-(1,2,5,6-tetrahydro-1-alkyl-3-pyridinyl)-2thiazolamine und 4-(hexahydro-1-alkyl-3pyridinyl)-2-thiazolamine.
ATE528279T1 (de) 3-butenyl-1-aminederivate und ihre verwendung als ih modulatoren von therapie für psychiatrische erkrankungen
ES545194A0 (es) Un procedimiento para preparar derivados de purina
IL111580A (en) Use of melatonin derivatives in the preparation of pharmaceutical compositions for use in treating sleep disorders
ATE239470T1 (de) Melatonin-derivate zur verwendung in der behandlung von desynchronisierungs-erkankungen
IE891407L (en) Side chain unsaturated 1-ó-hydroxyvitamin d homologs
DE68903019D1 (de) 4,5,6,7-tetrahydroisothiazolo (4,5-c)pyridin-derivate und isomere.
CS318690A3 (en) Pharmaceutical composition usable for depression therapy
IT8349055A0 (it) B-osso-l-carbammoil-pirrolpropionitrile, procedimento per la loro produzione, preparati farmaceutici con tenenti questi composti, nonche' il loro impiego terapeutico
ZA873928B (en) Topical methotrexate preparation for the treatment of hyperproliferative epithelial disease
EP0301449A3 (en) Enantiomers of propafenone-containing therapeutic agents
IL87867A (en) Preparation of pharmaceutical compositions containing a 2,6-diamino-3-phenyl-azo-pyridine derivative
NO170331C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive acyleringsprodukter av bis(2-imidazolin-2-ylhydrazoner)av 9,10-antracen- dikarboksaldehyd