[go: up one dir, main page]

DE112009001591A5 - Di- und Triphosphat-Prodrugs, insbesondere Nukleosiddi- und -Triphosphat-Prodrugs - Google Patents

Di- und Triphosphat-Prodrugs, insbesondere Nukleosiddi- und -Triphosphat-Prodrugs Download PDF

Info

Publication number
DE112009001591A5
DE112009001591A5 DE112009001591T DE112009001591T DE112009001591A5 DE 112009001591 A5 DE112009001591 A5 DE 112009001591A5 DE 112009001591 T DE112009001591 T DE 112009001591T DE 112009001591 T DE112009001591 T DE 112009001591T DE 112009001591 A5 DE112009001591 A5 DE 112009001591A5
Authority
DE
Germany
Prior art keywords
triphosphate
prodrugs
triphosphate prodrugs
particular nucleoside
nucleoside
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE112009001591T
Other languages
English (en)
Inventor
Chris Meier
Henning Jessen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitaet Hamburg
Original Assignee
Universitaet Hamburg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitaet Hamburg filed Critical Universitaet Hamburg
Publication of DE112009001591A5 publication Critical patent/DE112009001591A5/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/22Amides of acids of phosphorus
    • C07F9/24Esteramides
    • C07F9/2404Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/242Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of hydroxyaryl compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE112009001591T 2008-04-24 2009-04-24 Di- und Triphosphat-Prodrugs, insbesondere Nukleosiddi- und -Triphosphat-Prodrugs Withdrawn DE112009001591A5 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102008020633.4 2008-04-24
DE200810020633 DE102008020633A1 (de) 2008-04-24 2008-04-24 Nukleosiddi- und Nukleosidtriphosphat-Prodrugs
PCT/DE2009/000550 WO2009129798A2 (de) 2008-04-24 2009-04-24 Di- und triphosphat-prodrugs, insbesondere nukleosiddi- und -triphosphat-prodrugs

Publications (1)

Publication Number Publication Date
DE112009001591A5 true DE112009001591A5 (de) 2011-04-07

Family

ID=40874513

Family Applications (2)

Application Number Title Priority Date Filing Date
DE200810020633 Withdrawn DE102008020633A1 (de) 2008-04-24 2008-04-24 Nukleosiddi- und Nukleosidtriphosphat-Prodrugs
DE112009001591T Withdrawn DE112009001591A5 (de) 2008-04-24 2009-04-24 Di- und Triphosphat-Prodrugs, insbesondere Nukleosiddi- und -Triphosphat-Prodrugs

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE200810020633 Withdrawn DE102008020633A1 (de) 2008-04-24 2008-04-24 Nukleosiddi- und Nukleosidtriphosphat-Prodrugs

Country Status (2)

Country Link
DE (2) DE102008020633A1 (de)
WO (1) WO2009129798A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102014112055A1 (de) 2014-08-22 2016-02-25 Universität Hamburg Di- und Triphosphat-Propharmaka
EP3548087A1 (de) 2016-12-02 2019-10-09 Universität Hamburg Nukleosidtriphosphat und nukleosidtriphosphat-analog-prodrugs
EP4151646A1 (de) 2021-09-20 2023-03-22 Universität Hamburg 5-fluoruracilderivate als prodrugs zur krebsbehandlung
EP4356928A1 (de) 2022-10-20 2024-04-24 Universität Hamburg Nukleosid-diphosphat- oder diphosphonat-prodrugs oder nukleosid-analog-diphosphat- oder diphosphonat-prodrugs

Also Published As

Publication number Publication date
WO2009129798A3 (de) 2009-12-17
DE102008020633A1 (de) 2009-10-29
WO2009129798A2 (de) 2009-10-29

Similar Documents

Publication Publication Date Title
HRP20181774T1 (hr) Novi citostatski 7-deazapurinski nukleosidi
SI2801580T1 (sl) Nukleozidna fosforamidatna predzdravila
BRPI0922508A2 (pt) Análogos de nucleosídeo
IL213698A0 (en) Nucleoside phosphoramidates
BRPI0911410A2 (pt) análogos de carba-nucleosídeo para tratamento antiviral
ZA201008829B (en) Nucleoside cyclicphosphates
BRPI0819797A2 (pt) compostos de nucleosídeos antivirais
DK2114980T3 (da) Antivirale nukleosidanaloger
DK2511282T3 (da) Uracylspirooxetannukleosider
BRPI0911269A2 (pt) análogos de halicondrina b
PL4134790T3 (pl) Przetwarzanie sieciowe o obniżonym zużyciu energii
BRPI0915524A2 (pt) conjunto de aerofólio
BRPI0909488A2 (pt) brocha
BRPI0721981A2 (pt) Folha traseira para um artigo absorvente
BRPI0910534A2 (pt) terapia antiviral
EP2362725A4 (de) Antivirenergänzung formulierungen
IT1391276B1 (it) Casco perfezionato
DE602008004490D1 (de) Werkzeugwechselsystem
BRPI0911359A2 (pt) híbridos polímero - dendrímero
BRPI0814725A2 (pt) Composição antiviral
EP2138172A4 (de) Antiviraler wirkstoff
EP2147732A4 (de) Durch innenhochdruck geformter artikel
DE112009001591A5 (de) Di- und Triphosphat-Prodrugs, insbesondere Nukleosiddi- und -Triphosphat-Prodrugs
DE112009001912A5 (de) Orthodontischer Bauteil, insbesondere Bracket
EP2127675A4 (de) Antivirales mittel

Legal Events

Date Code Title Description
R119 Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee

Effective date: 20111101