DE102009008026A1 - Method for producing stack of medicament pockets that is utilized for storing and providing medicament wafers for e.g. contraception, involves stacking pockets so that markings are arranged in marking sections of pockets within each stack - Google Patents

Abstract

The method involves providing markings (3) at medicament pockets of a medicament pocket model (7) in marking sections (18). Rows (R) of the pockets are separated from each other along a separating line (23), and strips (13) are formed corresponding to the number of rows. The pockets are individualized by separating each individual pocket from the strips. The individualized pockets of the respective strip are stacked to a respective stack such that the respective markings are arranged in the consecutive marking sections at the pockets within each stack from one pocket to next pocket. An independent claim is also included for a medicament pocket model for producing a stack of medicament pockets comprising two rows of consecutive medicament pockets.

Description

Field of the invention

The The invention relates to a method for producing a stack of for the storage and provision of drug wafers Drug pouches using a drug pouch template, the medicine bag template and its uses for manufacturing a stack and for producing a device for storage and provision of drug wafers. The drug wafers contain medicines in layer form and are used in particular for used contraception or hormone replacement therapy.

State of the art

Pharmaceutical wafers are sheet-like devices containing pharmaceutically active agents contained in a drug carrier. The active substances in the wafers can be administered, for example, transmucosally, ie via the oral mucosa, by placing the wafers on or under the tongue, whereby the active substance carrier dissolves, thereby releasing the active substances. The wafers are provided enclosed in foil pockets. According to DE 101 59 746 B4 These pockets may consist of at least one carrier foil and at least one cover foil, wherein at least the areal larger foil has two parallel side edges and between the carrier foil and the cover foil the foil- or sheet-like material (wafer) is enclosed gas- and moisture-proof.

For the preparation of the device according to DE 101 59 746 B4 For example, the described foil pouches containing the drug wafers are simply collected into a stack and introduced into the device. The device for storing and providing the wafers described therein comprises an at least single-divided housing, against which the lateral edges of the stacked foil pockets abut, on a front inner side that edge of a carrier foil which projects beyond the edge of an associated cover foil. The stacked film bags are pressed by a spring against the upper inside of the housing. The front upper portion of the housing has two slots for separately discharging the carrier film and the cover film, whereby the wafer can be provided with the carrier film or with the cover film. The task of the spring is to hold together the remaining film pockets near the slots after removal of a foil bag and to position them for further removal. Between the slots, a separating tool for separating the carrier film from the cover sheet is arranged, against which the uppermost carrier film rests with its lying in front of the front edge of the cover sheet area. To transport the drug pockets from the housing serves a rotatable about a rotation axis transport element.

These Device with her succession to be removed drug pockets has the disadvantage that a user (in) when using the removed Drug bags for taking the drug wafers on the one hand has no control over whether one for a certain period predetermined intake already has taken place or still has to take place. Therefore, it can easily become one double intake, or the user forgets at all, to take the wafer.

To the others may be the user in this closed device Also, do not see how many wafers she / he has already taken or how long the intake has to last A particular disadvantage This device is moreover that the user due to the closed design also can not detect whether the device all drug bags necessary for the treatment at all contains. An opening of this compactly built Device is not intended and would destroy it.

The Completeness of a device containing drug wafers is however a basic requirement for the success of a medical treatment. This applies even more the use of drug wafers for contraception and for hormone replacement therapy. Therefore, at the Production of devices for time-dependent drug administration considerable effort for quality assurance expended. In addition, of course, too the user (s) of these devices at a control facility Interested.

Out The prior art is in terms of control over Time and frequency of intake of active substance units in the form of tablets, dragees o. Ä. So-called drug blister known, d. H. Facilities for storing tablets, dragees o. Ä., In which the tablets, dragees o. Ä. In contained in a first film embossed pockets and the film with a zipper closing the pockets second film is connected. Is taking the tablets of depending on a specific time, you can the second slide details, eg. As weekdays, be applied.

For example, in EP 0 166 763 B1 a blister is provided with pockets arranged in a row for the tablets. In the manufacture of the blisters, the pockets become uniquely the days of at least one calendar month Further, sequential integer numerical indicia are arranged in a one-to-one relation near the pockets such that each pocket is visually identifiable with one and only one calendar day of the calendar month and wherein consecutive integer numerical indicia are located near breakable zones in the second film in that they are visible from the back on the second sheet and each zone being visually identifiable with one and only one calendar day of the calendar month. This allows each pocket to be visually identified from both the front and back with one and only one calendar day. Thus, removal of the tablets on a daily basis and compliance with user compliance can be facilitated.

Furthermore, in EP 0 511 726 B1 describes an assembly for receiving tablets in a field, comprising: a blister pack having a predetermined area in which a plurality of tablets configured in a selected field are located, a container for receiving the blister pack, and a daily calendar placed on the panel of the tablets in the blister pack, wherein the daily calendar is slidable to position a selected start day on a first tablet in the field of tablets and wherein pointers are provided on the container and the blister pack has a locating notch close to and in proximity to a first tablet so that the first tablet to be taken is displayed.

Furthermore, in DE 10 2005 032 015 A1 discloses a case for receiving a blister pack having a first and a second half hinged thereto. The first Etuihälfte is designed as a pocket for receiving the blister pack and has an outer part and an inner visible part and first openings in the visible part and second openings in the outer part, wherein the first openings are aligned with the second openings, at least where the containers for the tablets are in the blister pack after picking up in the bag. The second half of the case has a compartment for receiving a display of the days of the week and windows for displaying the days of the week in an inner visible area of the second half of the compartment in the area of the compartment, wherein the windows are arranged such that they correspond to the columns of the containers of a pocket Blister pack are assigned.

These Embodiments of storage devices and However, providing drug units affects tablets in blister packs whose manufacturing process differs from manufacturing process for devices with drug wafers in drug pockets basically different.

From Therefore, an object of the present invention is a Drug bag template and a method of making a Stacks of for storage and provision of drug wafers serving medicine bags from the medicine bag template to create with which a stack can be generated, the / the User in using a control over the already withdrawn drug wafers allowed.

A Another object of the present invention is to provide the method for the production of the stack so that already during the Manufacturing process a simple control over the Completeness of the stack in terms of the number of Drug bags is possible. In particular, a should flawless stacking, allowing the stack contains too few or too many medicine bags. This is intended to reduce the costs by scrap and the cost of the final inspection of the produced stack or for the Quality assurance can be reduced.

A Still another object of the present invention is to Ensure that the wafers are in a given rhythm from the device depending on the period of use safely can be taken or taken, d. H. that the device is capable of giving the user control the prescribed intake over a certain period of time Allow drug wafers.

Summary of the invention

These and other objects are achieved by the present invention. Advantageous embodiments of the invention are in the Subclaims specified.

Typically, a drug pocket consists of a base sheet and a coversheet. The cover film can be connected to the base film, for example glued or welded, via a preferably strip-shaped connection running along the side edges of the cover film. Furthermore, in a particularly preferred embodiment, the base film and the cover film may each have on each at least one side edge protruding tabs which are not connected to each other. Thus, a pulling apart and thus opening the drug bag for removal of the wafer contained therein is greatly simplified, because the two slides can be easily grasped. A drug wafer is formed between the base sheet and the coversheet within the composition The area enclosed preferably air-tight and moisture-proof. Due to their structure or only in the area of the wafer, the film pockets can have a small elevation due to this condition.

The inventive method is used for the production a stack of for storage and provision of drug wafers serving pharmaceutical bags, each drug bag on a Marker edge one mark each in one of several side by side has marking portions arranged on the marking edge.

• a. Bereitstellen einer Arzneimitteltaschenvorlage, wobei die Arzneimitteltaschenvorlage mindestens zwei benachbarte Reihen von Feldern, aus denen die Arzneimitteltaschen durch Vereinzeln gebildet werden sollen, enthält und wobei die Markierungen auf in der Reihe aufeinander folgenden Feldern in aufeinander folgenden Markierungsabschnitten angebracht sind;
• b. Trennen der mindestens zwei benachbarten Reihen voneinander entlang mindestens einer die Reihen trennenden Trennlinie, wobei entsprechend der Anzahl der Reihen Streifen gebildet werden, die die in den Reihen aufeinander folgenden Arzneimitteltaschen enthalten;
• c. Vereinzeln der in den jeweils gebildeten Streifen enthaltenen Arzneimitteltaschen durch Abtrennen jeder einzelnen Arzneimitteltasche von deren Streifen; und
• d. Stapeln der vereinzelten Arzneimitteltaschen eines jeweiligen Streifens zu einem jeweiligen Stapel, so dass die jeweiligen Markierungen auf den Arzneimitteltaschen innerhalb jedes Stapels schrittweise von einer Arzneimitteltasche zur nächsten Arzneimitteltasche in aufeinander folgenden Markierungsabschnitten angeordnet sind.

The method according to the invention comprises the following steps:

• a. Providing a drug pocket template, wherein the drug pocket template includes at least two adjacent rows of fields from which the drug pockets are to be singulated, and wherein the markers are mounted on consecutive rows in successive marker portions;
• b. Separating the at least two adjacent rows from each other along at least one parting line separating the rows, forming strips corresponding to the number of rows containing the successive drug pockets in the rows;
• c. Separating the drug pockets contained in the respective strips formed by separating each individual drug bag from its strip; and
• d. Stacking the singulated drug pockets of a respective strip into a respective stack such that the respective markers on the drug pockets within each stack are arranged incrementally from one drug pocket to the next drug pocket in successive marker portions.

• a) Befördern der Arzneimitteltaschenvorlage in einer Transportrichtung, wobei die Arzneimitteltaschenvorlage mindestens zwei benachbarte Reihen der in der Transportrichtung aufeinander folgenden Felder enthält, wobei sich die Reihen parallel zur Transportrichtung erstrecken und wobei die Markierungen auf in der Reihe aufeinander folgenden Feldern in aufeinander folgenden Markierungsabschnitten angebracht sind;
• b) Trennen der mindestens zwei benachbarten Reihen voneinander entlang mindestens einer der Transportrichtung folgenden Trennlinie, wobei entsprechend der Anzahl der Reihen Streifen gebildet werden, die die in der Transportrichtung aufeinander folgenden Arzneimitteltaschen enthalten;
• c) Vereinzeln der in den jeweils gebildeten Streifen enthaltenen Arzneimitteltaschen durch Abtrennen jeder einzelnen Arzneimitteltasche von deren Streifen; und
• d) Stapeln der vereinzelten Arzneimitteltaschen eines jeweiligen Streifens zu einem jeweiligen Stapel, so dass die jeweiligen Markierungen auf den Arzneimitteltaschen innerhalb jedes Stapels schrittweise von einer Arzneimitteltasche zur nächsten Arzneimitteltasche in aufeinander folgenden Markierungsabschnitten angeordnet sind.

The method preferably comprises the following method steps:

• a) conveying the drug pocket template in a transport direction, wherein the drug pocket template contains at least two adjacent rows of successive fields in the transport direction, the rows extending parallel to the transport direction, and wherein the markers are mounted on consecutive rows in successive marking portions ;
• b) separating the at least two adjacent rows from one another along at least one separating line following the transport direction, whereby strips are formed corresponding to the number of rows and containing the successive drug pockets in the transport direction;
• c) separating the drug pockets contained in the respective strips formed by separating each individual drug bag from its strip; and
• d) stacking the singulated drug pockets of a respective strip into a respective stack so that the respective markings on the drug pockets within each stack are arranged incrementally from one drug pocket to the next drug pocket in successive marker sections.

The Drug bag template for making stacks of for storage and providing drug wafers serving pharmaceutical bags comprises at least two, preferably at least four and preferably at most twelve, for example four, eight, ten or twelve, preferably adjacent to the longitudinal direction of the Drug pocket template extending rows of consecutive Fields from which the drug pockets generated by dicing should be. Preferably, each drug pocket has one Marker edge one mark each in one of several side by side on the marking edge arranged sections. Furthermore is preferably on each drug pocket on the drug pocket template a mark so attached that the markings on in series of consecutive medicine bags in succession following marking sections are attached. Possibly follows in the rows a drug bag with a on one the first end of the marker edge mark on a Drug bag with a at a second end of the marker edge located mark.

In inventive way is the drug pocket template for making a stack of for storage and provision of Used for pharmaceutical wafers.

Farther The drug pocket template is also used to make a device used for storage and provision of drug wafers become. The device comprises i) a stack of the drug wafers containing drug pockets having preferably each seven marker sections at a marking edge and in each case a marking in one of Marking sections and ii) a support on which preferably seven times are arranged, with which the markings aligned.

The process according to the invention has the advantage over the prior art that the production of the stacks takes place with greater security det, because to be taken together in a stack of drug bags are first held together in strips and are separated from each other just before stacking by stacking. This reduces the risk of errors in the order of the drug pockets in the stack. Thus, the correct number of drug pockets and their order in the stack can be made easier.

About that In addition, the markings on the medicine bags can be checked whether the stacks have been created properly, such as by the stacks are scrolled through manually or mechanically and the order of the marks on the stack in succession Drug bags is controlled.

Thereby that the drug pockets in inventive Are provided with the markings, the user has (in) when using a stack to determine the possibility if you already have a portion of medication in the current period has taken or not. With the help of the markings on The medicine bags can thus be the progress of the intake the drug wafers are controlled. Take over the markings therefore in addition to the general test function the additional function of quickly assigning a specific drug wafer at a specific intake period.

Preferably may be prepared by the method according to the invention Stack for storage and provision of for Contraception or hormone replacement therapy serving drug wafers be used.

Detailed description

Preferably The medicine bag templates are in the form of bows in front of which are boxes containing the medicine bags correspond. In a preferred embodiment of the invention an arc comprises six mutually adjacent rows of each other following medicine bags and in each row seven consecutive Medicament pockets. With a preferred number of 28 medicine bags Accordingly, four arcs are used simultaneously for each stack Production of six piles needed.

In an alternative preferred embodiment of the invention For example, the medicine bag template in shape a long band are provided, the tape on a Roll (coil) can be wound and then in the transport direction for the procedure is unrolled. For example, includes a band six extending parallel to the transport direction adjacent rows of successive in the transport direction Fields for the medicine bags.

In a preferred embodiment of the method yourself on the medicine bag template at each marker edge the drug pockets have seven marker sections. The marks are preferably in the second drug pocket area. The markers will be consecutive in a row Fields on the medicine bag template on in successive Marking sections attached so that the markings in the 7-turn from drug bag to drug bag gradually change in position, d. H. from the first to the first to the seventh drug bag. If the medicine bag template contains more than seven fields in each row, for example 14 fields, begins the cycle of consecutive markings on in a series of consecutive fields from the eighth until the fourteenth drug bag, etc. then again. D. H. it is preferable to look at the medicine bag template in each row seen in the transport direction seven consecutive Drug pockets are located. This results after the separation and stacking the drug bags weekly piles, which eventually stacked to a monthly stack with 28 medicine bags can.

A Such dimensioning of the stacks with drug pockets is especially for use in contraception and for Hormone replacement therapy beneficial because in this case over several weeks, for example four weeks (28 days), once each a portion of medicine must be taken during the day. By recording of 28 medicine bags in a stack, the user can for consume a stack each such cycle.

If the drug wafers are to be taken daily are the times in a preferred embodiment weekdays or Calendar days, the latter represented by the numbering the days of a month. Weekdays are preferred and have the advantage over the calendar days that repetition occurs more frequently than the latter. This allows easier attachment of times on the carrier, since only for the first day the suitable day of the week chosen from the seven days of the week must become. The day of the week, calendar day or other Times are preferably at the beginning of a revenue phase of Drug wafer attached to the carrier.

The pharmaceutical bag template according to the invention preferably contains pharmaceutical wafers which Contain medicines for contraception or hormone replacement therapy. Within a range of drug pockets, there may be sub-sets of drug pockets containing drug wafers that are not drug-containing, such as placebo, or even drugs that are different from those of the other drug wafers (two-phase drugs). For example, in each 25.-28. Drug bag located in a row drug wafers that are placebos. This has the advantage that, for example, in the contraception, in which there are periods in which no medicines are to be taken, the usual intake of the wafers must not be interrupted because the placebos contain no active ingredients.

The Separating the at least two adjacent rows on a drug pocket template from each other along the dividing line following, for example, the transport direction is preferably done by cutting. Singling in the educated Strips contained drug pockets is preferably carried out by Cutting or punching. In a particular embodiment the invention can the separation of the strips from each other and the Separate the drug bags from the strips also done by punching.

Provided the medicine bag template still no openings for contains the medicine bags, these can during, before or after singulation into the medicine bag template or the drug pockets, for example by punching introduced become.

After this the stack by stacking the isolated drug pockets finished, this can be subsequently on a support arranged and connected thereto via a connecting element become. Or the medicine bags can be on the Carrier stacked and doing with the connecting element get connected. In both cases receives the Stack through the carrier for improved stability and can be handled more easily. In addition, the Wafer protected by the carrier against mechanical effects.

The Pharmaceutical bags preferably have mutually aligned openings through which the connecting element is passed. This will connect the medicine bags together and preferably arranged to be movable relative to one another. That has that Advantage that the small elevations in the drug pockets, in the drug bags caused by the drug wafers will be compensated. The medicine bags can characterized in an orderly manner in the stack. To this The first is an aesthetically pleasing device created. Secondly, the wafers in the stack become smaller Measurements are mechanically loaded and therefore stored gently.

The connecting element may be, for example, a rivet or another connecting element, which holds the pocket stack tamper-proof. In the case of a rivet, the connecting element can consist of two, for example, rod-shaped connecting element parts, which can be inserted into one another or screwed or glued together. The connecting element may be remote rod-shaped. In a further embodiment of the invention, the connecting element may also be formed in a compact construction in which it consists of two parts, wherein it, when assembled, can almost completely fill the openings in the medicament pockets. The connecting element may in particular comprise a box-shaped lower part with a web arranged therein for passage through the openings and a top part closing off the box-shaped lower part. Furthermore, the box-shaped lower part of the box-shaped connecting element may comprise a base plate, a wall resting on the base plate and partially enclosing and thus guiding the medicament pockets, and the web. In any case, a connection element is understood to mean a component which is passed through the openings in the medicament pockets and connects the medicament pockets. Thus, a rivet and also the web of the formed in a compact design connecting element can be understood as connecting elements. In the case of the bridge, it is of course necessary to hold the stack together additional suitable holding devices on the foot and the head of the bridge. These additional holding devices can be realized, for example, by the box construction consisting of the box-shaped lower part and the upper part. Alternatively, differently shaped foot and head parts may be provided at the foot and the head of the bridge, which hold the stack together. The web can also be designed as a rivet with two web-shaped rivet heads. When assembling of the connecting element forming connecting element parts they can lock together and are preferably not again non-destructively detachable from each other, or they can be glued together, welded or connected to one another at their joining technique. In all these cases, it is a so-called tamper-evident closure, ie a tamper evident closure. It is particularly preferred if the connection of the at least two parts which form the connecting element is achieved by positive locking. A rivet is to be understood as meaning a connecting element which consists of at least two parts which engage in one another and are connected to one another in a form-fitting manner, and further capable of stapling the stack of drug pockets interposed therebetween by respective head formations.

As well Is it possible to take the isolated medicine bags directly to stack on a support. In this case, the carrier already include the connecting element or a part of the connecting element. This ensures that the stack produced already mechanically is summarized and no longer in the subsequent handling can fall apart. This enables a secure production method.

In Each drug bag is preferably one for tearing each a second drug pocket area containing the drug wafer the drug bag from a first drug bag area serving perforation introduced. The perforation can, for example before applying the label on the drug pocket template be introduced into this or only afterwards. The perforation allows that the drug wafers are easily removed from the stack can, for example by tearing out or cutting out a second drug pocket area from the stack.

In A preferred embodiment of the invention is the Do not perforate across the entire width of the drug pockets but trained in a shortened overall, taking their both ends into slots. Through the slots will produces a notch effect which is the severing of the second medicament pocket regions further simplified. The introduction of the perforation can, for example done by suitable punching tools.

In a further preferred embodiment of the invention is another before stacking the isolated drug bags Step provided, in which the drug bags in addition are each provided with a peripheral recess, wherein the recesses in the stack of drug bag to drug bag incrementally grow larger, so over all medicine bags seen in the stack a staircase Course of the recesses forms and thus marks on all medicine bags are visible. These are preferably on the edge of each drug pouch within a stack seen in the direction of transport graphic marks, for example in the form of a symbol, such as a colored colon, a smiley, a logo or a crossbeam, applied, which gradually removed by the introduction of the recesses become. The recesses, for example, during of the manufacturing process punched out of the drug bag can look up in the finished stack each visible in the area of the recess graphic mark free on the medicine bag in the stack below. These graphic marks can already be printed on the medicine bag template be. The recesses and the thus recognizable graphic Brands have the advantage that the production staff or a suitable control device in the production of the stack its completeness and thus the number of medicine bags in the stack can easily check.

The Pharmaceutical bags are preferably formed from two laminates between which the drug wafer is located. The laminates can have the following layer sequence: polyethylene / aluminum / polyethylene terephthalate, wherein the polyethylene layers each abut the drug wafer and the polyterephthalate layers facing outward.

In a preferred embodiment of the invention is the Marking on one of the aluminum layers or one of the polyethylene terephthalate layers applied.

The produced by the method according to the invention Device is preferably carried out forgery-proof. For this purpose, one or more security features on the device provided a verification of authenticity allow the device, for example, imprints in micro-writing, Holograms, tipping or other security features.

The Figures described below are for general understanding the invention. But they are not meant to be limiting but are only intended to explain certain embodiments, which are preferred without other preferred embodiments excluded.

1 shows a schematic view of an embodiment of the drug pocket template; 1a : Variant of the template of 1 ;

2 shows a perspective view of a prepared from a drug pocket template stack in a first embodiment;

3 shows a further perspective view of a manufactured from a drug pocket template stack in a second embodiment with a first connecting element;

4 shows a perspective view of another embodiment of a wafer pocket booklet with a second connecting element in different stages of assembly; 4a : before stapling the pile; 4b : after stapling the pile; 4c after connecting to a carrier;

5 shows a perspective view of another embodiment of a wafer pocket booklet with the connecting element of 4 in different stages of assembly; 5a : Carrier with the connecting element; 5a-1 : first variant for arranging a weekday strip, 5a-2 , second variant for arranging a weekday strip; 5b : after installation of the stack, 5c : Device partially closed;

6 shows a perspective view of a prepared from a drug pocket template wafer pocket booklet with stepped recesses.

Same Reference numerals in the figures indicate like elements.

1 shows a schematic view of an embodiment of a drug pocket template, which is used for carrying out the method according to the invention for producing a stack. The medicine bag template 7 is formed in this embodiment as a bow.

The arc 7 has 6 × 7 = 42 fields 4 ' on, which correspond to medicine bags. The arc 7 includes six parallel to the direction in which the sheet is conveyed in the manufacture of the drug pockets (arrow 22 ), arranged and adjacent rows R of successive fields 4 ' and seven transverse to the transport direction 22 arranged columns S of fields 4 ' , The fields 4 ' for the drug pockets each have a perforation (not shown), via which a first drug pocket area and a second drug pocket area are interconnected. Furthermore, lateral notches may be provided on the perforations, such as in 1a shown. Continue to be in the fields 4 ' openings 8th punched out.

Adjacent to the openings 8th are in the fields 4 ' the marking sections 18 and markings 3 to be seen in the marking sections. Within a row R of seven consecutive fields 4 ' (Numbers in a circle) change the positions of the markers 3 gradually from field 4 ' to field 4 ' , By contrast, the positions of the markings remain 3 within a column S unchanged.

The illustrated adjacent six rows R each with seven fields 4 ' initially according to the invention along the dividing lines 23 in six stripes 13 cut before the medicine bags are separated from the strips. One strip each 13 is then further processed by separating each individual drug bag. The thus separated drug bags are then stacked on each other, for example, to weekly stacks. Subsequently, another arc 7 processed according to the same procedure. From a sheet, for example, six weekly stacks are generated. By placing another 21 drug bags on each of the first sheet 7 received six first week stacks, which consisted of three other sheets 7 are obtained, a total of six stacks are formed, each containing 28 drug pockets. By first the stripes 13 are generated and then the drug pockets are cut off from the respective strips or separated by punching, the belonging to a stack drug pockets are held together as long as possible in the form of the strip. Only immediately before the stacking of the drug bags these are from the strips 13 disconnected. Thus, mis-sorting is avoided, so that the security in the production of the stack is increased.

A variant of the drug pocket template of 1 is in 1a shown. This template 7 differs from that described above in that eight rows of each seven fields are provided for the preparation of drug pockets. Furthermore, each field has an oval opening 8th as well as a perforation 19 as well as notches 20 on. In addition, the template is on both sides 7 protruding edges 31 in which there are continuous perforations 32 are located. These perforations 32 serve to transport the template 7 , like a film transport.

2 shows a stack produced by the process according to the invention 1 for storage and provision of drug wafers 2 serving medicine bags 4 . 4 ' . 4 '' wherein the drug pockets are connected after stacking or already during stacking. Every medicine bag 4 . 4 ' . 4 '' has a marker at each edge of the marker 3 in one of a plurality of marking portions arranged side by side on the marking edge 18 on (only on top of drug bag 4 shown). The medicine bags 4 . 4 ' . 4 '' have second drug pocket areas 11 and first drug pocket areas 10 each with a mutually aligned opening 8th on. Through the opening 8th is the connecting element 9 passed. The connecting element 9 connects the medicine bags 4 with each other and arranges these movably to each other. The opening 8th is as a slot and the connecting element 9 designed as a rivet. The first medicine bag areas 10 and the second drug areas 11 each have a perforation 19 connected to each other, so that the separation of the drug wafer 2 located in the second drug pocket area 11 is located from the first drug pocket area 10 at the perforation 19 is relieved. This leaves the first drug bag area 10 in the pile 1 ,

3 shows a preferred embodiment of a batch produced by the method according to the invention 1 for storing and providing drug wafers 2 with a first embodiment of a connecting element 9 for the stack 1 , 3 is essentially similar to the structure of the wafer pocket booklet 2 , although in contrast to 2 the marks 3 and the marker sections 18 not adjacent to the perforation 19 but at the opposite edge of the drug pocket areas 11 , The stack 1 consists of several medicine bags 4 . 4 ' . 4 '' , The medicine bags 4 . 4 ' . 4 '' have second drug pocket areas 11 and first drug pocket areas 10 each with a mutually aligned opening 8th on. The opening 8th is designed as a slot.

The medicine bags 4 . 4 ' . 4 '' are in this embodiment in contrast to that of 2 through a compact connecting element 9 consisting of a lower connecting element part 9a and an upper connector part 9b Connected to the opening 8th fully fills in the assembled state, wherein the connecting element is in the form of a rivet.

The lower connector part 9a grips through the oblong holes from below 8th therethrough. The columnar rivet holders 9d . 9e of the lower connector part 9a are on a base plate 9c fastened so spaced apart that the outer edges of the rivet holders loosely abut the rounded slot ends. These outer edges are slightly tilted towards the top (enlarged view of the rivet holder 9e ), so that the successively on the lower connector part 9a applied medicine bags 4 . 4 ' . 4 '' with their respective slot 8th easy on this part 9a ride up. After the whole pile 1 is formed, the rivet is closed by the upper connecting element part 9b between the columnar rivet holders 9d . 9e is pressed. For the positive connection of the upper connecting element part 9b with the lower connector part 9a For this purpose, both parts have tooth-shaped side surfaces which dig together. After the connecting element 9 is closed, the stack can 1 be handled without fear that its integrity in handling could be compromised. In addition, the riveted stack 1 also be used to refill a carrier.

The first medicine bag areas 10 and the second drug pocket areas 11 each have a perforation 19 connected together, the overall perforation being shorter than in 2 is formed, ie not over the entire width of the drug pockets 4 . 4 ' . 4 ' extends but at both ends in slots 20 goes over, which act like a notch. This will remove the drug wafer 2 by even easier separation of the second drug pocket area 11 from the first drug pocket area 10 at the perforation 19 facilitated. The first medicine bag area 10 remains after the separation of the second drug pocket area 11 in the wafer pocket booklet.

In the production of the pile 1 becomes the lower connector part 9a for example, held by a holding device or optionally a carrier, and the isolated drug pockets 4 . 4 ' . 4 '' or the finished stack 1 comes with the openings 8th on the lower connector part 9a placed. Subsequently, the connecting element 9 by placing the upper connector part 9b closed.

In 4a . 4b and 4c A further embodiment of a wafer pocket booklet in different assembly stages is shown in perspective view.

The stack 1 includes a variety of drug bags 4 For example, 28 bags, of which only the uppermost drug bag is visible. The medicine bag 4 contains a welded wafer 2 , At the bottom of the medicine bags 4 there are marking sections 18 , On one of the marker sections 18 there is a mark 3 ,

The medicine bags 4 are notched on two sides in the upper area at 20 and have a perforation 19 on. In addition, the medicine bags 4 slots 8th on, by in the assembled state a bridge 15 reaches through.

In 4a is above the stack 1 the connecting element 9 shown, which is constructed in two parts: The connecting element 9 has a lower part 24 and a top 26 on. The lower part 24 includes the footbridge 15 as well as a frame 27 both on a base plate 28 are attached. The jetty 15 grips through the oblong holes from below 8th therethrough. The frame 27 limits the base plate 28 partially on three sides as well as on the fourth page. Where is this frame 27 not located, can the medicine bags 4 about the perforation 19 rich passing connecting part. By the way, this frame surrounds 27 the upper part of the medicine bags 4 flush and thus provides an external guide for the drug pockets so that they sit tightly in the wafer pocket booklet without play. The upper part of the connecting element 9 is through a plate 26 formed on the lower part 24 can be attached positively or cohesively. In cohesive connection, the plate 26 for example, by means of ultrasonic welding with the lower part 24 get connected. For a positive connection, for example undercuts on one of the two parts and projecting parts are provided on the other of the two parts.

After the connecting element 9 is locked, the stapled stack 1 be handled without any problem, without having to worry about the integrity of the stack 1 could be affected during handling.

The lower part 24 of the connecting part 9 is preferably on a support 5 , For example, by gluing, attached. In the production of the stack 1 from medicine bags 4 becomes the carrier 5 together with the lower part 24 preferably submitted. The medicine bags 4 then be on the carrier 5 hung up, the bridge 15 of the on the carrier 5 attached lower part 24 each in the slot 8th the bags 4 slides into it. Through this bridge 15 as well as the frame 27 become the medicine bags 4 on the carrier 5 held. In addition, their position is determined by the frame 27 exactly determined.

After stacking all drug bags together 4 forming the stack 1 becomes the carrier 5 with a weekday strip 6 Mistake. The weekday strip 6 is attached so that it with the marker sections 18 on the medicine bags 4 flees. This allows the user to recognize on which day of the week the wafer 2 the overhead medicine bag 4 must be taken.

The carrier 5 is then folded so both at the bottom so that this end a lid 29 for the wafer pocketbook. On the lid 29 For example, information about the manufacturer and the name of the medicinal product may be appropriate. The lid 29 extends essentially over the entire surface of the drug pockets 4 ,

The upper end of the carrier 5 will not be folded over. At this point forms the connecting element 9 a box that closes the wafer pocket booklet at the top. The lid 29 extends over the connecting element 9 , Both parts are connected by a releasable closure. For example, on the inside of the lid 29 and on the outside of the connecting element 9 Magnetic fasteners may be appropriate, ie on one side of a metal strip and on the other side of a magnetized metal strip. These two elements can also be hidden in the respective components.

5a . 5b . 5c show a further embodiment of a wafer pocket booklet in various stages of assembly.

The stack 1 includes a variety of drug bags 4 For example, 28 bags, of which only the uppermost drug bag is visible. The medicine bag 4 contains a welded wafer 2 , At the bottom of the medicine bags 4 there are marking sections 18 , On one of the marker sections 18 there is a mark 3 , In the under the upper visible drug pocket 4 lying (not visible) second drug bag, this mark is mounted on the marking portion, which is adjacent to the first marking portion, in which the mark is located on the uppermost drug pocket.

The medicine bags 4 are notched on two sides in the upper area at 20 and have a perforation 19 on. In addition, the medicine bags 4 slots 8th on, by in the assembled state of the wafer pocket booklet a bridge 15 reaches through.

In 5a is the lower connector part 24 on the carrier 5 shown. The connecting element is as in the embodiment of 4 constructed in two parts: it has a lower part 24 and a top 26 on. The lower part 24 includes a footbridge 15 a frame 27 as well as a base plate 28 , The jetty 15 grips through the oblong holes from below 8th therethrough. The frame 27 sits on the edge of the base plate 28 on. He limits the base plate 28 partially on three sides as well as on the fourth page. Where is this frame 27 not located, can the medicine bags 4 about the perforation 19 rich passing connecting part. Incidentally, this framework encompasses 27 the upper part of the medicine bags 4 flush and guides them so that they sit tightly in the wafer pocket booklet. The upper connector part 26 is formed by a plate which on the lower connecting element part 24 can be attached positively or cohesively. This plate 26 is with the carrier 5 for example, materially bonded (gluing o. Ä.).

The lower connector part 24 is on the carrier 5 attached for example by gluing. In the production of the stack 1 from medicine bags 4 become the carriers 5 with the lower connector part 24 preferably submitted. The medicine bags 4 then be on the carrier 5 hung up, the bridge 15 of the on the carrier 5 fixed lower part 24 each in the slot 8th the bags 4 slides into it. Through this bridge 15 as well as the frame 27 become the medicine bags 4 on the carrier 5 held. In addition, will their position through the frame 27 exactly determined.

After stacking all drug bags together 4 a wafer pocketbook becomes the carrier 5 with a weekday strip 6 Mistake. The weekday strip 6 can both at the in 5a-1 as well as at the in 5a-2 be shown attached position. The weekday strip 6 is attached so that it with the marker sections 18 on the medicine bags 4 flees. This allows the user to recognize on which day of the week the wafer 2 the overhead medicine bag 4 must be taken.

The carrier 5 is then folded over at the top so that the end is a cover 30 for the wafer pocketbook. On the cover 30 For example, information about the manufacturer and the name of the medicinal product may be appropriate. The cover 30 extends over the entire surface of the drug pockets 4 as well as the supernatant of the carrier 5 at the bottom of the wafer pocket booklet.

To the crimping and closing of the connecting element assembled the wafer pocketbook.

6 shows a perspective view of a prepared from a drug pocket template wafer pocket booklet with a stack 1 in essence, too 3 , but with the medicine bags 4 . 4 . 4 '' additionally one recess each 16 exhibit. The recesses 16 are each located on one edge of the medicine bags 4 The first and second drug pocket areas 10 . 11 together, with the individual recesses in the successive drug pockets 4 . 4 ' . 4 '' are designed such that they are incrementally larger from drug bag to drug bag. This results in all drug bags 4 . 4 ' . 4 '' seen a staircase shape of the recesses 16 from drug bag to drug bag. The recesses 16 which, for example, during the manufacturing process from the drug bag 4 . 4 ' . 4 '' punched out, give the view of one each in the area of the recess 16 introduced graphic brand 21 , shown as a colon, on the pile 1 underlying medicine bag 4 ' . 4 '' free.

The stack 1 is on a support in this embodiment 5 arranged. The stack 1 and the carrier 5 are through two rivets 9 connected with each other. Optionally, only a rivet could 9 ' or for example, the connecting element according to 3 for the connection of Sta pel 1 and carriers 5 be used. On top of the drug bag 4 are in the second drug pocket area 11 the mark 3 and the marker sections 18 to see.

The carrier 5 In this embodiment, it has one over the lower edge of the second medicament pocket regions 11 protruding area 17 and on the area 17 times 6 on, with the times 6 , here weekdays, with the marking sections 18 aligned.

The times 6 are applied, for example, by sticking and have the weekday "Mo", "Tues", "Wed", "Do", "Fr", "Sa", "So" on. The strip is prepared so that the start day of the week appears at the far left. On the overhead medicine bag 4 is a first mark aligned with the day of the week "Mo" 3 appropriate. Further markings 3 are not shown as these are from the overlying drug pockets 4 are covered.

QUOTES INCLUDE IN THE DESCRIPTION

This list The documents listed by the applicant have been automated generated and is solely for better information recorded by the reader. The list is not part of the German Patent or utility model application. The DPMA takes over no liability for any errors or omissions.

Cited patent literature

• - DE 10159746 B4 [0002, 0003]
• EP 0166763 B1 [0008]
• - EP 0511726 B1 [0009]
• - DE 102005032015 A1 [0010]

Claims (20)

Method for producing a stack ( 1 ) for the storage and provision of drug wafers ( 2 ) serving pharmaceutical bags ( 4 ), each drug bag ( 4 ) at a marker edge in each case a mark ( 3 ) in one of a plurality of marking portions arranged next to each other on the marking edge ( 18 ), comprising the following steps: a. Providing a drug pocket template ( 7 ), wherein the medicine bag template ( 7 ) at least two adjacent rows (R) of fields ( 4 ' ), from which the medicine bags ( 4 ) are to be formed by singling, and wherein the markings ( 3 ) in the row (R) of successive fields ( 4 ' ) in successive marker sections ( 18 ) are attached; b. Separating the at least two adjacent rows (R) from each other along at least one dividing line separating the rows (R) ( 23 ), where according to the number of rows (R) stripes ( 13 ) forming the successive drug pockets (R) in rows (R) ( 4 ) contain; c. Separating the strips formed in each case ( 13 ) containing pharmaceutical bags ( 4 ) by separating each individual drug bag ( 4 ) of their strips ( 13 ); and d. Stacking the isolated medicine bags ( 4 ) of a respective strip ( 13 ) to a respective stack ( 1 ), so that the respective markings ( 3 ) on the medicine bags ( 4 ) within each stack ( 1 ) progressively from a drug bag ( 4 ) to the nearest medicine bag ( 4 ) in successive marker sections ( 18 ) are arranged. A method according to claim 1, characterized in that it comprises the following method steps: a. Carrying the medicine bag template ( 7 ) in a transport direction ( 22 ), wherein the medicine bag template ( 7 ) at least two parallel to the transport direction ( 22 ) adjacent rows (R) of the in the transport direction ( 22 ) successive fields ( 4 ' ) and where the markings ( 3 ) in the row (R) of successive fields ( 4 ' ) in successive marker sections ( 18 ) are attached; b. Separating the at least two adjacent rows (R) from each other along at least one of the transport direction ( 22 ) following dividing line ( 23 ), where according to the number of rows (R) stripes ( 13 ) are formed, which in the transport direction ( 22 ) successive medicinal bags ( 4 ) contain; c. Separating the strips formed in each case ( 13 ) containing pharmaceutical bags ( 4 ) by separating each individual drug bag ( 4 ) of their strips ( 13 ); and d. Stacking the isolated medicine bags ( 4 ) of a respective strip ( 13 ) to a respective stack ( 1 ), so that the respective markings ( 3 ) on the medicine bags ( 4 ) within each stack ( 1 ) progressively from a drug bag ( 4 ) to the nearest medicine bag ( 4 ) in successive marker sections ( 18 ) are arranged. Method according to one of the preceding claims, characterized in that at each marking edge seven marking sections ( 18 ) are located. Method according to one of the preceding claims, characterized in that the stack ( 1 ) 28 medicine bags ( 4 ) contains. Method according to one of the preceding claims, characterized in that the stack ( 1 ) on a support ( 5 ) and with this via a connecting element ( 9 ) or that the medicine bags ( 4 ) on the support ( 5 ) and with this via the connecting element ( 9 ) get connected. Method according to one of the preceding claims, characterized in that in each drug pocket ( 4 ) one each for tearing off the drug wafer ( 2 ) containing second drug pocket area ( 11 ) of the drug bag ( 4 ) from a first drug pocket area ( 10 ) serving perforation ( 19 ) is introduced. Method according to claim 6, characterized in that the marking ( 3 ) in the second drug pocket area ( 11 ) is located. Method according to one of the preceding claims, characterized in that the separating of the at least two adjacent Rows (R) are made from each other by cutting. Method according to one of the preceding claims, characterized in that the separation of the strips formed in the strips ( 13 ) containing pharmaceutical bags ( 4 ) by cutting or punching done. Method according to one of the preceding claims, characterized in that the medicament pocket templates ( 7 ) Arches are. A method according to claim 10, characterized in that each sheet six adjacent rows (R) of the successive drug pockets ( 4 ) and seven successive medicinal bags in each row (R) ( 4 ). Method according to one of the preceding claims, characterized in that prior to the stacking of the isolated medicament pockets ( 4 ) a further step is provided in which the medicament pockets ( 4 ) additionally each with a peripheral recess ( 16 ), the recesses ( 16 ) in the stack ( 1 ) of drug bag ( 4 ) to drug bag ( 4 ) grow incrementally, so that over all drug pockets ( 4 ) seen in the stack ( 1 ) a step-shaped course of the recesses ( 16 ). Method according to one of the preceding claims, characterized in that the drug wafers ( 2 ) are designed for use for contraception or hormone replacement therapy. Drug bag template ( 7 ) for producing a stack ( 1 ) for the storage and provision of drug wafers ( 2 ) serving pharmaceutical bags ( 4 ), wherein the medicine bag template ( 7 ) at least two adjacent rows (R) of successive drug pockets ( 4 ) and each drug bag ( 4 ) at a marker edge in each case a mark ( 3 ) in one of a plurality of marking portions arranged next to each other on the marking edge ( 18 ) and wherein on each drug bag ( 4 ) on the medicine bag template ( 7 ) a mark ( 3 ) is mounted in such a way that the markings ( 3 ) in the row (R) of consecutive drug pockets ( 4 ) in successive marker sections ( 18 ) are mounted. Drug bag template ( 7 ) according to claim 14, characterized in that at each marking edge seven marking sections ( 18 ) are located. Drug bag template ( 7 ) according to one of claims 14 and 15, characterized in that in each row (R) seven medicament pockets ( 4 ) are located. Drug bag template ( 7 ) according to any one of claims 14-16, characterized in that the drug wafers ( 2 ) Contain medicines for contraception or hormone replacement therapy. Drug bag template ( 7 ) according to any one of claims 14-17, characterized in that the medicament pockets ( 4 ) additionally each marginally graphic marks ( 21 ) exhibit. Use of the drug pocket template ( 7 ) according to one of claims 14-18 for the production of a stack ( 1 ) for the storage and provision of drug wafers ( 2 ) serving pharmaceutical bags ( 4 ). Use of the drug pocket template ( 7 ) according to any one of claims 14-18 for the manufacture of a device for the storage and provision of drug wafers ( 2 ) comprising i) a stack ( 1 ) of the drug wafers ( 2 ) containing pharmaceutical bags ( 4 ) each having seven marking sections and ii) a carrier ( 5 ), on which seven times ( 6 ) are arranged, with which the markings ( 3 ) are aligned.