DE102007054019A1 - Injection device with actuation-activated clutch - Google Patents

Abstract

Injection device for administering a product, comprising: a) an actuating device (6, 7, 12, 13) which rotates when actuated for administration, b) an output device (9, 10) which rotates for the administration of the product c) an engaging member (13), which upon actuation of the actuating means (6, 7, 12, 13) for the administration of the product from a decoupled state in which the actuating means (6, 7, 12, 13) relative to the Output device (9, 10) is rotatable, in a coupled state, in which the actuating device (6, 7, 12, 13) rotatably coupled to the output device (9, 10) is movable.

Description

The The invention relates to an injection device for administration a particular liquid product, such as B. a drug. For example, with the injection device Insulin preparations, Growth hormones or others in a similar way medicines to be administered to a human or animal Patients are administered. The injection device may be together or be sold separately with a separate drug, the by User of the injection device is used in this. Prefers the injection device is connected to one in the injection device distributed drug contained, causing the injection device can also be considered as a disposable injection device, the after complete product distribution is disposed of.

Out In the prior art, a drug containing disposable injection devices known, which are completely disposed of after the product has been distributed. Such injection devices should be both inexpensive to manufacture also easy and safe to use.

It is therefore an object of the invention, an injection device to provide that meets these requirements.

The Task is solved by the features of claim 1. Advantageous developments from the dependent ones claims and the description.

The Injection device according to the invention comprises an actuating device, the on actuation for the Administration performs a rotational movement. The actuating device can be done by a work agent, such as B. one Motor or a spring actuated become. Preferably, the actuator is powered by muscle power z. B. by the pressure of a finger of the user on the actuator actuated. It is thus preferable for the injection device to have access from the outside is possible on the actuator. For example, the actuator proximally from a housing the injection device protrude and, for example, the proximal end form the injection device. The initiating a product distribution Power can be up first the actuating device and subsequently on one of the actuator downstream element or downstream elements, such as. Legs Output device, act.

The actuator may be one-piece or preferably multi-part. She can in particular also be axially movable in addition to their rotational mobility. Prefers exists between the actuator and a housing the injection device threaded engagement, d. H. that the housing in the actuator or the actuator in the case intervenes. The thread preferably has a self-locking slope. The actuating device can then be screwed into or out of the housing.

The Injection device further comprises an output device which for the Administration of the product rotates. The Output device or at least a part of the output device transmits his / her Movement on the product, especially on a piston, on the product works to dispense product. It is therefore preferred that the output device or at least a part of the output device an axial movement, preferably in the discharge direction can perform. The output device may be in one piece or preferably in several parts be.

The actuator and the output device are coupled to each other in a product distribution, ie during actuation of the actuator for a product distribution, in particular rotationally fixed. The injection device for this purpose comprises an engagement member which, upon actuation of the actuator for the administration of the product from a decoupled state in which the actuating device is rotatable relative to the output device in a coupled state in which the actuator is rotatably coupled to the output device, movable is or is moving. The engagement member is preferably formed on or by the actuating device or at least of a part of the actuating device. Preferably, the engagement member is formed axially fixed to the actuator or to a part of the one or more part actuator. For example, the actuating device, in particular the engagement member - if it is not in engagement with the output device - relative to the output device rotatably movable or längsbewegbar or preferably both. This is particularly advantageous for the mounting of the injection device or the setting of a product dose, since the actuator is movable independently of the output device. If the actuator is rotatably coupled via the engaging member with the output device - such. As in the operation of the actuator for a product distribution - the actuator or at least the engaging member relative to the output device preferably only be moved axially. The actuator or a part thereof can cooperate in the operation with the output device or with their part acting on the piston so that this or this by a larger, same or more preferably smaller way in Is moved longitudinally, as the actuator. In other words, it is preferred that the movement of the actuating device is transmitted in a restricted manner to the output device or to the part of the output device which acts on the piston. For example, the output device or a part thereof may have a thread which engages in the housing or a housing-fixed part and has a smaller pitch than the thread with which the actuating device engages in the housing or a housing-fixed part, whereby the reduction is effected. For the sake of completeness, it should be mentioned that with equal thread pitches the ratio of the axial movements of the actuating device and the output device or a part thereof is 1 and that if the output device has a greater thread pitch than the actuating device, the output device or the part acting on the piston thereof performs a larger axial movement than the actuator.

In preferred embodiments includes the actuator a coupling member and a guide member. The engagement member may be attached to the coupling member on the guide member or as a separate part between coupling member and guide member be formed. At the operation the actuator is the coupling member relative to the guide member to a clutch stroke axially movable. The operation consists of a clutch stroke and a drive stroke, wherein in the coupling stroke, the engaging member with the output device rotatably coupled with the drive and the rotation with the actuator coupled drive means a drive stroke or a Ausschütthub to the piston for a product distribution is moved, executes. In particular, in the moving around the coupling stroke coupling member the engagement member in the coupled state.

The actuator may comprise a spring member which between the coupling member and guide member acts to make this in an unactuated Squeeze state so that the engaging member is in a decoupled state with the Drive device is located. The spring member can be a separate Spring member, such as. B. a coil spring made of metal or plastic be. The spring member may in particular with at least one of coupling member and guide member be firmly connected. The spring member may alternatively be a separate Spring also in one piece on the coupling member or the guide member be formed. The advantage achieved by this is that the spring during injection molding of the preferably made of plastic coupling member or guide member can be made with equal, which has the advantage that a separate part can be saved.

coupling member and guide member are preferred only by a limited route, in particular the clutch stroke, movable relative to each other. For this purpose, coupling member and guide member interlocking stops having the movement of the unactuated coupling member relative to guide member prevent against the direction of the clutch stroke. Especially Also, the spring member may be arranged so that it has this effect achieved.

Prefers are coupling member and guide member rotatably relative to each other, in particular permanently non-rotatably coupled. Coupling member and guide member can For this purpose, interlocking longitudinal guides exhibit. Likewise preferred is that the engagement member rotatably, in particular permanently rotationally fixed relative to the coupling member or the guide member is.

The Engagement member may be a first transmission element and a coupling member and guide member may have a second transmission element, wherein during movement the coupling member to the coupling stroke, the first transmission element and engage the second gear member, thereby the engagement member from the decoupled state in the coupled Condition is moved. The transmission elements can, for example, on each other sliding surfaces, such as B. inclined planes, which is an axial movement of the first Transmission element in a radial to the longitudinal axis of the injection device convert directed movement of the second gear member. Prefers have the first transmission element radially outward and the second transmission element radially inward. The engaging member may be an engaging portion have, in engagement with the output device, the actuating device rotatably coupled with the output device, but preferably one Axial movement of the actuator relative to the output device permits. Preferably, the engagement region has radial inside.

The Engaging member may be a separate part of the coupling member and / or the leader for one radial movement is performed. However, it is preferred that the engagement member on a coupling member from or guide member, in particular is formed in one piece. It is further preferred that the engagement member is formed on a resilient arm, the z. B. already during the injection molding process made of the coupling member or the guide member can be.

The arm may extend from the location where it is attached to the coupling member or the guide member at least partially in the circumferential direction, ie, about the longitudinal axis of the injection device. In a likewise preferred alternative For example, the arm may extend in the axial direction, ie, approximately parallel to the longitudinal axis of the injection device. There may be several such arms, such. B. two arms, may be provided, each having an engaging member and are preferably distributed uniformly over the circumference of the coupling member or the guide member. It is generally preferred that the arm is connected at one end to the coupling member or the guide member and at its other end has the engagement member.

In preferred embodiments the output device comprises circumferentially distributed and longitudinal the injection device extending grooves. In these grooves is the engagement member movable into engagement, wherein in this engagement between Engagement member and output device an axial relative movement possible and a rotational movement is locked. In the combined rotational and axial movement, d. H. Screwing, which the actuator during its Actuation, in particular during the drive stroke, is preferred between the engagement member and the output device only an axial relative movement instead. Generally preferred, that in the coupled state of the engaging member, the actuating device and the output device acting in the same direction rotational movement To run.

The Output device may be one or more parts. Preferably can the output device when actuated the coupling member an axial movement in the discharge direction to a piston, which acts on a product.

In an embodiment can the output device, in particular a piston rod, z. B. apart from acting on the piston flange, in one piece be formed, wherein the piston rod at its outer periphery of the above-mentioned grooves for the Engaging the engaging member and a thread which overlies the grooves is, has. In particular, you can the areas between two adjacent threads arranged areas have the grooves. The thread of the piston rod can be in one Engagement with the housing the injection device, wherein the piston rod at her Rotation a dispensing movement, d. H. one to be distributed Product or piston acting on the product.

In alternative preferred embodiments The output device is multi-part and includes at least one Output member and a piston rod. In particular, the output device have a driven member, which is sleeve-shaped, for example. Furthermore, the output device a piston rod, which preferably from the driven member is surrounded. Output member and piston rod can be connected together be that a rotational movement of the output member an axial movement the piston rod causes. Preferably, the output member is relatively to the housing the injection device rotatably and axially fixed.

According to one first variant, the piston rod, for example, with a thread engage in the output member, so that a rotational movement of the output member relative to the piston rod relative to an axial movement of the piston rod to the housing and causes the output member. The piston rod can be relatively to the housing rotatably and axially slidably received in the housing or thereof be stored. Suitable means for this are in the longitudinal direction the piston rod extending groove or flattening. The thread, with which the piston rod engages in the output member, in this case in reverse to the thread, with which the actuating device engages in the housing.

According to one second, preferred variant, the output member is non-rotatable with the piston rod is connected, wherein the piston rod relative to the output member is axially movable. Suitable means for this are in the longitudinal direction the piston rod extending groove or flattening. Preferably, the attacks Piston rod with its thread in the housing, so that one on the Piston rod transmitted rotary motion of the output member, the piston rod screwed in the distal direction. In this case, it is preferable that the thread of the piston rod has the same sense of rotation as the thread with the actuator in the case intervenes.

Generally it is preferred that the thread of the piston rod is a smaller one Slope has as the thread with which the actuator in the housing intervenes.

Preferably is the actuator, in particular the guide member the actuator in a threaded engagement with the housing, allowing a rotational movement the actuator causes their axial movement. For this purpose, the actuating device, in particular the guide member at least one Abragung, for example, in shape a threaded section-shaped Cam and which can be formed into a housing formed by the housing Thread engages. The thread has a sufficiently large pitch so that no self-locking occurs, d. H. that an axial up the actuating device practiced Force implemented in a rotational or screwing movement of the actuator becomes. Because the guide member preferred rotatably connected to the coupling member, turn on actuation, especially in the drive stroke both guide member and coupling member.

In preferred embodiments will be forward or during the clutch stroke, d. H. if the coupling member is not yet around the Clutch stroke is moved, the actuator, in particular, the coupling member just out, so that an unwanted Rotary movement of the actuator relative to the housing is prevented. This can be achieved by the housing of the Injection device in the actuator engages, in particular by means of a locking member. The intervention of the Locking member in the coupling member is preferably strong enough to the Actuation device for or while to block the clutch stroke against an unwanted twist, but weak enough to allow a desired rotational movement of the actuator. It means that at a z. B. applied by the user of the device Torque on the actuator, in particular, the coupling member is rotatable. When applied to the actuator axial force z. By the user of the injection device No or only a small torque is generated, which is not sufficient for the just run Coupling member, in particular the latching engagement of the housing in the coupling member to solve.

The Coupling member may be at its outer periphery have at least one profile section, in which the locking member of the housing engages and the actuator at the beginning and also during the clutch stroke locks against an unwanted rotational movement. Of the at least one profile section can in the circumferential direction of the coupling member juxtaposed and longitudinally extending grooves that form the profile. Conveniently, the grooves have flattened flanks corresponding to a desired, on the actuator applied torque engaging in the grooves locking member Press against an elastic force out of engagement. Alternatively or additionally also the locking member which engages in the grooves corresponding Have flanks, so that the locking member out of engagement with the Grooves pressed will, if a sufficiently large Torque is applied. The actuating direction can at least rotated in one direction of rotation, preferably in both directions of rotation be when the actuator not yet activated is.

Preferably has the actuating device, in particular the coupling member, at least one threaded portion on, in which the housing or that on the case educated while the coupling stroke engaging in the at least one profile section Detent member engages when the coupling member to the Kupplungshubs is moved. This makes possible, that the actuating device during the further operation, d. H. while the drive stroke the for the product distribution required rotational movement relative to the housing can perform. The at least one Threaded portion may have a profilarmen reason. The reason can from the outer circumference the coupling member formed in the region of the at least one threaded portion become. The at least one threaded portion or its base can a less pronounced one Profile than the at least one profile section. hereby will that for a rotation of the coupling member required torque reduced or / and at the same time a weak audible or when turning tactile Click generated. Preferably, the profilarme threaded portion or its reason profile-free, which makes the rotation of the coupling member Required torque even stronger can be reduced. The at least one threaded portion of the Coupling member may have the same pitch as the thread of the housing, in which the actuating device, in particular the guide member intervenes. While of the drive stroke, the coupling member may be a combined rotary and perform axial movement and with the at least one threaded portion along the locking member along slide.

Of the At least one profile section may be preferred in at least one be limited in both axial directions of a threaded portion. The threaded sections can groove shape be. The at least one threaded section and / or the at least a profile section can partially or completely, in particular, wind several times around the circumference of the coupling member. For example, you can a plurality, in particular two profile sections and / or threaded sections over the Circumference be arranged.

Prefers is the at least one threaded portion in the circumferential direction of one in the longitudinal direction the coupling member extending, profilarmen, especially even limited profile free section. This will make the production the coupling member simplified. Preference is given to two profile arms Sections and two profile sections evenly distributed around the circumference, the in particular each may have the same arc length, whereby each section about about a quarter of the circumference extends. In this embodiment may be preferred two locking members may be provided, in the circumferential direction in 90 ° and in the axial direction by a quarter of the pitch of the at least one threaded portion can be offset. This ensures that always a locking member in a Thread portion or a profile section engages.

In preferred embodiments, the adjustment of a product dose to be distributed is possible with the actuating device, for which reason the actuating device can also be used as a dosing actuator direction can be designated. The dosage of the dispensed product dose can be made by means of a rotary movement of the actuator relative to the housing and the output device. In particular, during the adjustment of the product dose, the actuating device is not actuated, ie the engaging element is decoupled from the output device. By rotation on the coupling member, a torque is applied, which is large enough to release the locking engagement of the housing in the coupling member in angular increments. With each rotation of the coupling member by a certain angle step is by clicking out and locking the housing from one groove to the next audible click and preferably also felt. Each click can stand for a certain dose of product, which also allows visually impaired people to adjust the desired product dose. Conveniently, for metering, ie for increasing the dose of product, the actuating device can be screwed proximally out of the housing. For dosing, ie to reduce the dose of product, the actuator is screwed in the distal direction, ie in the housing. After the desired dose of product has been adjusted, the actuator is actuated by an applied force in the distal direction, whereby locking member comes into engagement with the at least one threaded portion from engagement with the at least one profile section. At the same time the engagement member is brought into engagement with the output device, so that upon further actuation of the actuator, the drive stroke of the actuator is carried out, whereby the actuator and the output device are rotated, which ultimately leads to a movement of the output device or a part thereof in the delivery direction and thus leads to product distribution.

The Injection device, in particular the operation submission can also have a dose indicator with which the set product dose visually is readable. For example, a dose display drum may be provided be, the rotationally and axially fixed to the actuator, in particular with is connected to the coupling member. In preferred embodiments For example, the dose indicating drum may at least provide the actuating means partially surrounded. The dose indicator drum may be at its periphery a helical one arranged dose scale, in particular with a slope, which corresponds to the pitch of the thread with which the actuator and the case are coupled. For example, the dose-indicating drum may be of the type casing or part of the housing be surrounded, preferably a window for reading a particular Scale value, the scale applied to the dose display drum having. In the product distribution, in which the actuator screwed into the housing in the distal direction, the dose indicator drum is also set in a screwing motion, whereby the set product dose corresponding to the drive stroke of actuator turns back. At more complete successful distribution the dose 0 appears in the window.

Preferably, several dosages and product distributions can be made with the injection device. In order to prevent a larger dose being set than product is in the injection device, a stop member may be provided which serves at the last dose setting to allow only the setting of a product dose equal to the rest of the product contained in the injection device equivalent. The stop member is preferably in threaded engagement with the actuator. Preferably, the stop member is sleeve-shaped and between the actuating device, in particular the coupling member, the z. B. may have the thread for the stop member, and the output device, in particular arranged the driven member. The thread in which the stop member engages preferably has a smaller pitch than the thread with which the actuator is in engagement with the housing and also preferably but not necessarily a smaller pitch than the thread with which the output means is in engagement with the housing. The stop member is preferably in engagement with the output device in such an engagement that the stop member is rotatably and longitudinally movable relative to the output device. Preferably, this engagement, as well as the engagement in the thread of the actuator permanently. During adjustment of a product dose, the actuator is rotatable relative to the output device and also relative to the stop member. Due to the threaded engagement of the actuator with the stop member and the longitudinal displaceability of the stop member relative to the output device, the stop member is axially displaced during dose setting. Since, in a product distribution, the actuating device and the output device are rotationally fixed relative to one another, the stop element is not displaced relative to the actuating device or to the output device during the product discharge. The injection device preferably comprises a stop, the z. B. be formed by the actuator to which the stop member is moved a bit further at each dosage. In the last presettable dosage with the injection device, the stop member is moved into engagement with the stop. A further metering is thus no longer possible since the stop member located in the stop with the actuating device blocks an increase in the product dose. This ensures that no higher product dose is set can be than can actually be distributed, which can be advantageous advantageous misuse can be avoided.

The This invention has been described in terms of preferred embodiments. Hereinafter the invention will be described with reference to preferred embodiments. The features disclosed here each form individually in the combinations also advantageous with the preceding description, the invention further. Show it:

1A to 1D different views of an injection device in an initial state,

2A to 2D different views of the injection device from the 1A to 1D in a condition with set product dose,

3A to 3D different views of the injection device from the 1A to 1D in a state after completed clutch stroke,

4 a perspective view of a housing and a coupling member in a state with a set product dose,

5 a perspective view of a housing and a coupling member in a state after completion of the coupling stroke,

6 an actuating device with arms extending in the longitudinal direction of the injection device for an engaging member,

7 different views of an injection device with extending in the longitudinal direction of the injection device arms for an engaging member and before a coupling stroke,

8th different views of the injection device 7 after completion of the coupling stroke,

9 an actuator having circumferentially extending arms for an engaging member;

10 various views of an injection device with circumferentially extending arms for an engaging member and before a coupling stroke,

11 different views of the injection device 10 after completion of the coupling stroke,

12 a coupling member, a guide member and a combination thereof with an arm extending in the longitudinal direction of the injection device for an engaging member, and

13 a coupling member, a guide member and a combination thereof and a circumferentially extending arm for an engaging member.

The reference numerals used in the figures indicate the same or at least similar parts, unless stated otherwise. The invention will be initially based on 1A to 3D described.

The injection device comprises an actuating device 6 . 7 . 12 . 13 in a multipart housing 1 . 2 . 3 is arranged. The housing 1 . 2 . 3 has an outer housing 1 , an inner case 2 , which is rotationally and axially fixed to the outer housing 1 is connected and a functional sleeve 3 on, which is also rotationally and axially fixed to the outer housing 1 and the inner housing 2 connected is. In principle, the housing could be formed in one piece. Due to the multi-part of the housing, however, there are advantages during assembly.

In the case 1 . 2 . 3 is a product container 4 arranged, which has a distal, intended for a needle end and a proximal, with a displaceable piston 4a has closed end. By displacement of the piston 4a in the distal direction, the product is released, whereby the distal direction can also be referred to as the delivery direction. Distal becomes the product container 4 closed by a septum that can be perforated by the needle when attached to the housing. The injection device shown is provided with an inserted product container 4 delivered. The product container 4 is not interchangeable, so it is a so-called disposable injection device. Basically, the product container could 4 also directly from the outer housing 1 be formed.

The injection device further comprises an output device 9 . 10 . 11 that is an output member 9 , one in the output member 9 received, with an external threaded piston rod 10 and one at the distal end of the piston rod 10 arranged flange 11 having. About the flange 11 becomes a dispensing movement on the piston 4a transferred in the distal direction for a product distribution. The flange 11 is relative to the piston rod 10 freely rotatable and axially fixed to the piston rod 10 coupled.

Like from the 1C and 13 it can be seen has the piston rod 10 Flattening on, in which the sleeve-shaped output member 9 engages and thus a rotation of the piston rod 10 in relation to the output member 9 permanently prevented, however, an axial displacement of the piston rod 10 relative to the output member 9 allows. The output member 9 is by means of a on the housing 1 . 2 . 3 , in particular on the functional sleeve 3 formed pivot bearing 3a relative to the housing 1 . 2 . 3 rotatably and axially fixed. The threaded rod 10 engages with its external thread in the internal thread 3c the functional sleeve 3 one.

In addition, it should be mentioned that in an alternative embodiment, the piston rod 10 with its thread in a sleeve-shaped output member 9 formed internal thread engage and, for. B. with its flattening, rotatably and axially displaceable by the function sleeves 3 can be included. The piston rod 10 However, then has a thread with a sense of rotation, which is opposite to the direction of rotation of the thread in the first described embodiment.

A rotation of the output device, ie the output member 9 and the piston rod 10 in one direction causes an axial displacement of the piston rod 10 in the distal direction due to the threaded engagement of the piston rod 10 with the thread of the functional sleeve 3c or - alternatively - the output member 9 , In other words, the piston rod 10 screws in the distal direction. About the freely rotatable flange 11 becomes the screwing movement of the piston rod 10 in an axial movement of the piston 4a , ie transferred to a delivery stroke, whereby the product is distributed. To turn back the piston rod 10 to prevent the other direction of rotation, engages the functional sleeve 3 with a locking element 3d in sawtooth, over the circumference of the output member 9 distributed ribs 9a one. Each sawtooth rib 9a have a flat and steep flank. The flat flank allows the output member 9 to turn in one direction, at which the piston rod 10 is moved in the distal direction. The steep flank prevents rotation of the output member 9 in the other direction of rotation, causing the piston rod 10 would be screwed in the proximal direction. This ensures that the piston rod 10 only in the distal direction, that can be screwed in the delivery direction. The sawtooth ribs 9a are distal to the area of the output member 9 who is in the pivot bearing 3a is arranged. Proximal of this area has the output member 9 evenly distributed over its circumference and extending in the longitudinal direction of the injection device grooves on such. B. off 1C is apparent. These grooves are sawtooth-shaped in the embodiment shown, but may also have other shapes, in particular symmetrical tooth shapes. The grooves serve on the one hand as anti-rotation and as a longitudinal guide for a sleeve-shaped stop member 8th , which is the output member 9 surrounds and with its inside in the grooves of the output member 9 intervenes. Thus, the stopper is 8th relative to the output member 9 permanently rotationally fixed and axially displaceable.

The on the outer circumference of the output member 9 arranged grooves are also used, in particular predominantly, to a rotation between the actuator 6 . 7 . 12 . 13 and the output device 9 . 10 . 11 optionally to produce a rotational movement of the actuator 6 . 7 . 12 . 13 on the output device 9 . 10 . 11 transferred to. The actuating device 6 . 7 . 12 . 13 also serves for dose adjustment in the embodiment shown, which is why it is also used as dosing and actuating device 5 . 6 . 7 . 12 . 13 can be designated. The metering and actuating device 5 . 6 . 7 . 12 . 13 includes a dose indicator drum 5 placed in an annular gap between the sleeve-shaped inner housing 2 and sleeve-shaped outer housing 1 is arranged. The dose indicator drum 5 has a helical around the dose display drum 5 running dose scale on. The currently set product dose is through that in the outer housing 1 formed windows 1a ( 1A ) readable. At the proximal end of the dose indicator drum 5 is a handle formed ( 1A ), on which the user of the injection device by gripping and turning a torque on the dose display drum 5 and thus on the metering and actuating device 5 . 6 . 7 . 12 . 13 , in particular for dose adjustment exercise. The dose indicator drum 5 has at its proximal end region further on a radially inwardly formed shoulder on the z. B. a stop 5a for the proximal end of the stop member 8th can be formed. The function of the stop member 8th will be described later in more detail.

An actuator designed as a button 12 is at the proximal end of the actuator 5 . 6 . 7 . 12 . 13 , freely rotatable and axially fixed. Thus, at a later actuation of the actuator 5 . 6 . 7 . 12 . 13 the actuator 12 relative to the housing 1 . 2 . 3 as an adapter for z. B. a thumb of the user of the device relative to the housing 1 . 2 . 3 stand firm while the rest of the actuator 5 . 6 . 7 . 12 . 13 relative to the housing 1 . 2 . 3 performs a rotational movement.

The actuating device 5 . 6 . 7 . 12 . 13 further includes an with the dose display drum 5 axially and rotatably locked, sleeve-shaped coupling member 6 , The coupling member 6 has at its inner periphery an internal thread, which is in an external thread of the stop member 8th , in particular permanent, engages. The thread has a relatively small pitch, which is preferably only so large that the thread is self-locking.

At the outer periphery of the coupling member 6 are distributed over the circumference arranged profile sections 6b comprising a plurality of juxtaposed, longitudinally extending and profile-forming ribs or grooves 6a have arranged. Such as B. off 1C it can be seen has the coupling member 6 in cross-section over the circumference of two profile sections 6b and two profile arms, here profile-free or smooth sections 6c on. Each profile section 6b becomes circumferentially on each side of a profile-free section 6c limited. Each profile section 6b has several, evenly spaced grooves 6a on. The profile sections 6b and the profile-free sections 6c extend in the cross section of the coupling member 6 about substantially the same circular arc section length. In the example shown, each of the sections is 6b . 6c in about a quarter of the circumference of the coupling member 6 long.

The grooves 6a are formed by radially outwardly projecting ribs, which also extend in the longitudinal direction, wherein between two adjacent ribs, a groove is arranged. The ribs or the grooves 6a have flattened flanks, so that engaging in the groove locking member 2 B , preferably as a locking cam 2 B is formed, with a sufficient on the coupling member 6 applied torque out of engagement with a groove 6a is pressed and engaged with the next groove 6a device. This will create an audible or tactile click.

The locking cam 2 B is on the inner case 2 via a springy arm, the locking cams 2 B against the outer periphery of the coupling member 6 pushes, educated. The inner housing 2 has a total of two such locking cams, wherein the two locking cams in the circumferential direction by 90 ° and in the axial direction by a quarter of the way, the coupling member 6 performs a complete rotation, are axially offset. Because the profile sections 6b and the profile-free sections 6c each extend about 90 ° around the circumference, it is ensured that upon rotation of the coupling member 6 always one of the two locking cams 2 B in a profile section 6b and the other of the two locking cams 2 B in the profile-free section 6c intervenes. This causes the profile sections 6a only partially over the circumference of the coupling member 6 extend, a simple manufacture of the coupling member 6 allows.

The coupling member 6 has at its periphery further threaded portions 6d , In particular threaded guides or thread grooves, extending through the profile sections 6b , ie in sections over the circumference of the coupling member 6 extend. The threaded sections 6d are at least as wide in the longitudinal direction of the injection device, as the locking cams 2 B ,

In an unactuated state of the actuator 5 . 6 . 7 . 12 . 13 is at least one of the two cams 2 B in engagement with a groove 6a , The threaded sections 6d have the same pitch as the coupling member 6 covered in one turn. The offset in the axial and circumferential directions locking cams 2 B of the inner housing 2 are z. B. particularly clearly in the 4 and 5 shown.

The metering and actuating device 5 . 6 . 7 . 12 . 13 further comprises a guide member 7 , which in this embodiment rotatably with the coupling member 6 connected is. The coupling member 6 is axial, ie along the longitudinal axis of the injection device in particular by a Kupplungshub h displaced. The guide member 7 has at least one, in this example two radially projecting engagement cam 7a on which sections over the circumference of the guide member 7 extend. The inner housing 2 has an internal thread 2a in the shape of a helically encircling groove into which the engagement cam 7a extends. The intervention cam 7a Therefore, although it only partially extends over the circumference has a corresponding helical form or pitch to in the thread 2a to fit. A rotational movement of the guide member 7 thus causes its axial movement and vice versa. The way the actuator 5 . 6 . 7 . 12 . 13 traverses in one revolution corresponds to the pitch of the thread 2a , The threaded sections preferably also have 6d the same pitch as the thread 2a , The thread 2a is a double-threaded, with a first engagement cam 7a in the first thread and a second engagement cam 7a engage in the other thread.

The coupling member 6 is along the longitudinal axis relative to the guide member 7 limited in both directions and movable to the Kupplungshub h. To fall out of the actuator 5 . 6 . 7 . 12 . 13 from the proximal end of the housing 1 . 2 . 3 To prevent, a movement of the coupling member 6 relative to the guide member 7 in the proximal direction by axially engaging, on the coupling member 6 and the guide member 7 formed stop pairs 16 formed, such. In 12 , middle representation, can be seen. As in 13 can be seen, this task can also be designed as a clasp spring member 15 , which surrounds a cam b hook-shaped and on the coupling member 6 is attached, take over.

By the spring member 15 become the coupling member 6 and the guide member 7 pressed as far apart as the above-mentioned travel limits allow it.

The coupling member 6 may be about a clutch stroke h relative to the guide member 7 be moved in the distal direction, wherein the spring member 15 ( 12 and 13 ) is stretched.

The actuating device 5 . 6 . 7 . 12 . 13 has an engaging member 13 on. The engaging member 13 can, as in the 6 - 8th and 12 respectively. 9 - 11 and 13 is shown to be arranged in various ways. However, the arrangements shown have in common that the engaging member 13 during the movement of the coupling member 6 relative to the guide member 7 in the distal direction radially inward, that is pressed in the direction of the longitudinal axis of the injection device. The inwardly pressed engaging member 13 engages with his intervention area 13a ( 12 and 13 ) in the outer periphery of the driven member 9 formed grooves. As a result, an anti-rotation between the output member 9 and engaging member 13 educated. The engaging member 13 is in turn rotationally fixed with the dosing actuator 5 . 6 . 7 . 12 . 13 ie with the coupling member 6 ( 12 ) or the guide member 7 ( 13 ) connected.

The in the 6 - 8th and 12 respectively. 9 - 11 and 13 shown engaging members 13 also have in common that they are arranged in particular at the end of a resilient arm. The resilient arm is on the coupling member 6 ( 12 ) or on the guide member 7 ( 13 ) in particular formed in one piece. The arm makes it possible for the engaging member 13 when moving the coupling member 6 pressed by the clutch stroke h in the distal direction into the engagement and when moving the coupling member 6 in the coupling stroke h opposite direction from the engagement with the output member 9 is moved.

The engaging member 13 has a first transmission element 13b which points radially outward. The first transmission element 13b has a gear surface, which is formed according to the mechanism of action of an inclined plane on. The transmission element 13b is engaged with a second gear member during execution of the clutch stroke 14 brought by the guide member 7 ( 12 ) or the coupling member 6 ( 13 ) can be formed. The second transmission element 14 has a radially inwardly facing gear surface, which can also act according to the laws of an inclined plane. When moving the coupling member to the Kupplungshub h get the gear surfaces of the first gear member 13b and the second transmission element 14 in an engagement and slide on each other, so that the engaging member 13 is pressed radially inward.

The engaging member 13 can, as in 12 shown along the longitudinal axis of the injection device have. The curvature corresponds to the radius at which the arm is spaced from the longitudinal axis. In the in 12 The example shown is the arm on which the engaging member 13 is arranged on the coupling member 6 attached. Alternatively, the arm pointing along the longitudinal axis could be on the guide member 7 be arranged, in which case the second transmission element 14 on the coupling member 6 instead of the guide member 7 could be arranged.

The engaging member 13 can, as in 13 is shown formed on a circumferentially extending, curved arm. As in 13 is shown is the arm 13 on the guide member 7 formed, wherein the second transmission element 14 on the coupling member 6 is formed. Alternatively, the circumferentially extending arm could be on the coupling member 6 be arranged, in which case the second transmission element 14 on the guide member 7 could be arranged.

Be particularly advantageous, as in 12 shown, serpentine spring members 15 or, as in 13 is shown, designed as a clasp spring members 15 exposed.

The function of the injection device will now be described below: The injection device is preferably in the in the 1A to 1D shown state delivered. The coupling member 6 is from the in 12 or 13 illustrated spring member 15 relative to the guide member 7 pressed in the proximal direction and held there. The metering and actuating device 5 . 6 . 7 . 12 . 13 is still unconfirmed. One dose is not yet set. At least one locking cam 2 B engages in a profile section 6b of the coupling member 6 one. The metering and actuating device 5 . 6 . 7 . 12 . 13 and the output device 9 . 10 are not rotationally locked in this state.

To adjust a dose of product, the user of the injection device will place it at the proximal end of the dose indicating drum 5 formed handle with a torque applied. By this torque, the metering and actuating device 5 . 6 . 7 . 12 . 13 rotated, causing them to become threaded 7a . 2a in the proximal direction of the housing 1 . 2 . 3 screwed. One of the two locking cams 2 B engages in a profile section 6b ie in a groove 6a one with the other locking cam 2 B in a profile-free section 6c intervenes. That means that on the dosing and actuating device 5 . 6 . 7 . 12 . 13 Applied torque must be large enough that the locking cams 2 B out of engagement with the grooves 6a is pressed. As a result, an audible or tactile signal is generated which indicates the rotation of the metering and actuating device 5 . 6 . 7 . 12 . 13 indexed. The output device 9 . 10 performs no rotation during the metering, since the engaging member 13 not in the output member 9 intervenes. An unintentional rotation, z. B. caused by the clicking vibrations is caused by the latching engagement of the locking element 3b in the output member 9 prevented.

The coupling member 6 , with an internal thread in the non-rotatable with the output member 9 connected stop member 8th engages, during the dosage leads a rotational movement relative to the stop member 8th because of the thread engagement, the stop member 8th towards the stop 5a is moved. The stopper 8th is in the 2 and 3 deviating from 1 drawn only in the representations C, which does not mean, however, that no stop member 8th is available.

In 4 is shown as the inner case 2 and the coupling member 6 at the end of a dose setting and before actuation of the dosing and actuating device 5 . 6 . 7 . 12 . 13 interact. In particular, it can be seen that a cam 2 B in the grooves 6a of the profile section 6b intervenes.

The 2A to 2D show the injection device in an overdosed condition, where the desired product dose in the window 1a is readable. The metering and actuating device 5 . 6 . 7 . 12 . 13 is in this state still umbetätigt to initiate the product distribution is the metering actuator 5 . 6 . 7 . 12 . 13 pressed and first, as in the 3A to 3D shown, the coupling member 6 together with the actuator 12 and the dose indicator drum 5 in the distal direction about the clutch stroke h relative to the guide member 7 postponed.

By the engagement of the cams 2 B in the grooves 6a becomes the coupling member 6 for the clutch stroke h straight led. At the end of the clutch stroke h at least one of the cams engage 2 B in the threaded section 6d and the other of the two cams 2 B in the profile-free section 6c one ( 5 ). Further, at the end of the clutch stroke h, the engaging member 13 in the rotationally fixed engagement with the output member 9 brought. The 3A to 3D show the injection device in a shifted by the coupling stroke h state. In a further operation, ie displacement of the metering and actuating device 5 . 6 . 7 . 12 . 13 this performs the drive stroke, which is the delivery stroke of the piston rod 10 causes.

During the drive stroke, the dose indicator drum screws 5 , the coupling member 6 and the guide member 7 due to the thread engagement 7a . 2a distally into the housing 1 . 2 . 3 and offset due to the engagement of the engaging member 13 in the output member 9 the piston rod 10 in a directed in the same direction of rotation rotation, alternatively - in a threaded engagement between the piston rod and driven member - in no rotation.

This causes the piston rod to move 10 due to their engagement in the functional sleeve 3a in the distal direction, ie discharge direction, causing the piston 4a is taken in the distal direction. Product is distributed.

Because between coupling member 6 and output member 9 during the drive stroke of the coupling member 6 , ie during the product distribution, no relative movement takes place, the distance between the proximal end of the stop member remains 8th and the stop 5a constant. After the metering and actuating device has been pushed back completely into its original position, can be metered anew, whereby the stop member 8th again towards the stop 5a is moved. This can be repeated until the stop member 8th to the stop 5a abuts, at which moment an increase in the product dose is no longer possible, even if the scale value of the dose display drum 5 allow another dosage. The distance of the stop member to the stop 5 is tuned to the stop member 8th to the stop 5a then strikes when the piston 4a in a distribution then carried out its most distal position.

The 6 . 7 and 8th show the injection device in the embodiment with an axially extending arm for the engaging member 13 wherein the arm on the coupling member 6 is attached. In 7 is the injection device with an unactuated metering and actuating device 5 . 6 . 7 . 12 . 13 shown ie that the engaging member 13 not in the output member 9 intervenes. A shift of the coupling member 6 around the clutch stroke h ( 7 ) causes the engaging member 13 in the output member 9 engages, causing the coupling member 6 relative to the output member 9 rotatably coupled ( 8th ).

In the 9 . 10 and 11 In the embodiment, the injection device is provided with a circumferentially extending arm for the engagement member 13 shown. The arm is in this example on the guide member 7 arranged. In 10 the injection device is shown in an unactuated state, that is, the engagement member 13 not in the output member 9 intervenes. When the rotary and axial fixed with the dose display drum 5 connected coupling member 6 around the clutch stroke h ( 10 ) is shifted, the engaging member 13 due to the interaction of the transmission elements 13b and 14 radially inwardly into a rotationally fixed engagement with the output member 9 pressed.

Claims (22)

Injection device for administering a product, comprising: a) an actuating device ( 6 . 7 . 12 . 13 ) which, when actuated, makes a rotational movement for the administration, b) an output device ( 9 . 10 ) which rotates for the administration of the product, c) an intervention member ( 13 ) which, when the actuating device ( 6 . 7 . 12 . 13 ) for the administration of the product from a decoupled state in which the actuating device ( 6 . 7 . 12 . 13 ) relative to the output device ( 9 . 10 ) is rotatable in a coupled state, in which the actuating device ( 6 . 7 . 12 . 13 ) rotatably with the output device ( 9 . 10 ) is movable. Injection device according to claim 1, characterized in that the engaging member ( 13 ) on the actuating device ( 6 . 7 . 12 . 13 ) is arranged. Injection device according to one of the preceding claims, characterized in that the actuating device ( 6 . 7 . 12 . 13 ) a coupling member ( 6 ) and a guide member ( 7 ), wherein upon actuation of the actuating device ( 6 . 7 . 12 . 13 ) the coupling member ( 6 ) relative to the guide member ( 7 ) is axially movable about a coupling stroke (h), wherein in the case of the coupling member (h) moved around the coupling stroke (h) 6 ) the engaging member ( 13 ) is in the coupled state. Injection device according to one of the preceding claims, characterized in that the engagement member ( 13 ) a first transmission element ( 13a ) and one of coupling member ( 6 ) and guide member ( 7 ) a second transmission element ( 14 ), wherein during the movement of the coupling member ( 6 ) about a coupling stroke (h) the first transmission element ( 13a ) and the second transmission element ( 14 ) engage, whereby the engaging member ( 13 ) is moved from the decoupled state to the coupled state. Injection device according to one of the preceding claims, characterized in that the engagement member ( 13 ) an intervention area ( 13a ) in engagement with the output device ( 9 . 10 ) the actuating device ( 6 . 7 . 12 . 13 ) with the output device ( 9 . 10 ) rotatably coupled. Injection device according to one of the two preceding claims, characterized in that the engagement region ( 13a ) radially inward and / or the first transmission element ( 13b ) pointing radially outwards. Injection device according to one of the two preceding claims, characterized in that the engagement member ( 13 ) on one of the coupling member ( 6 ) or the guide member ( 7 ) formed arm is formed. Injection device according to the preceding claim, characterized in that the arm extends in the circumferential direction Injection device according to claim 7, characterized in that that the arm extends in the axial direction. Injection device according to one of the preceding claims, characterized in that the coupling member ( 6 ) and the guide member ( 7 ) are rotatably coupled relative to each other. Injection device according to one of the preceding claims, characterized in that the output device ( 9 . 10 ) distributed in the circumferential direction and extending in the longitudinal direction of the injection device grooves, into which the engaging member ( 13 ) is engageable, wherein in the engagement between a handle member ( 13 ) and output device ( 9 . 10 ) An axial relative movement possible and a rotational movement is locked. Injection device according to one of the preceding claims, characterized in that the output device ( 9 . 10 ) has a thread which is in engagement with a housing ( 1 . 2 . 3 ) of the injection device, wherein the output device ( 9 . 10 ) Whose rotation is a Ausschüttbewegung performs. Injection device according to one of the preceding claims, characterized in that the output device ( 9 . 10 ) an output member ( 9 ) and a piston rod ( 10 ), wherein the piston rod ( 10 ) relative to the output member ( 9 ) rotationally fixed and axially displaceable in the output member ( 9 ) is arranged, wherein the piston rod ( 10 ) in a threaded engagement with a housing ( 1 . 2 . 3 ), whereby the piston rod ( 10 ) is moved in its rotation in the discharge direction, and wherein the engaging member ( 13 ) with the output member ( 9 ) in an engagement, the relative rotation between actuator ( 6 . 7 . 12 . 13 ) and output unit ( 9 . 10 ) locks, can be brought. Injection device according to the preceding claim, characterized in that the output member ( 9 ) relative to the housing ( 1 . 2 . 3 ) is rotatable and axially fixed. Injection device according to one of the preceding claims, characterized in that the actuating device ( 6 . 7 . 12 . 13 ), in particular especially the guiding element ( 7 ) is in threaded engagement with the housing, so that a rotational movement of the actuating device ( 6 . 7 . 12 . 13 ) causes the axial movement. Injection device according to one of the preceding claims, characterized in that the housing ( 1 . 2 . 3 ) of the injection device in the actuator ( 6 . 7 . 12 . 13 ) engages that the actuating device ( 6 . 7 . 12 . 13 ) in the not yet about the coupling stroke (h) moving coupling member ( 6 ) is guided straight, so that an unwanted rotational movement of the actuating device ( 6 . 7 . 12 . 13 ) relative to the housing ( 1 . 2 . 3 ) is prevented. Injection device according to one of the preceding claims, characterized in that the coupling member ( 6 ) at least one profile section ( 6b ), in which the housing ( 1 . 2 . 3 ) and the actuating device ( 6 . 7 . 12 . 13 ) locks at the beginning and also during a clutch stroke (h) against an unwanted rotational movement. Injection device according to one of the preceding claims, characterized in that the actuating device ( 6 . 7 . 12 . 13 ), in particular the coupling member ( 6 ) at least one threaded section ( 6d ), in which the housing engages when the coupling member ( 6 ) is moved about the coupling stroke (h), wherein the at least one threaded portion ( 6d ) has the same thread pitch as the thread ( 2a ) of the housing ( 1 . 2 . 3 ) into which the actuating device ( 6 . 7 . 12 . 13 ), in particular the guide member ( 7 ) intervenes. Injection device according to one of the preceding claims, characterized in that when the coupling member ( 6 ) is moved about the clutch stroke (h), the actuator can perform a combined rotational and axial movement. Injection device according to one of the preceding claims, characterized in that with the actuating device ( 6 . 7 . 12 . 13 ) a dosage of a dispensed product dose by means of a rotary movement of the actuator ( 6 . 7 . 12 . 13 ) relative to the housing ( 1 . 2 . 3 ) and the output device ( 9 . 10 ) is vornehmbar. Injection device according to the preceding claim, characterized in that the housing ( 1 . 2 . 3 ) in engagement with the actuating device ( 6 . 7 . 12 . 13 ), which is strong enough, the actuator ( 6 . 7 . 12 . 13 ) for the clutch stroke (h) to lock against unwanted rotation, but weak enough, a voluntary rotational movement of the actuator ( 6 . 7 . 12 . 13 ) to allow. Injection device according to one of the preceding claims, further comprising a stop member ( 8th ), which with the actuating device ( 6 . 7 . 12 . 13 ) in a threaded engagement and with the output device ( 9 . 10 ) in such an engagement that the stop member ( 8th ) relative to the output device ( 9 . 10 ) is rotationally fixed and longitudinally movable.