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DE08771330T1 - Vorrichtung und verfahren für automatische einführung, blasenentfernung, reinigung und kalibrierung einer spektralsonde während einer auflösungsprüfung - Google Patents

Vorrichtung und verfahren für automatische einführung, blasenentfernung, reinigung und kalibrierung einer spektralsonde während einer auflösungsprüfung Download PDF

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Publication number
DE08771330T1
DE08771330T1 DE08771330T DE08771330T DE08771330T1 DE 08771330 T1 DE08771330 T1 DE 08771330T1 DE 08771330 T DE08771330 T DE 08771330T DE 08771330 T DE08771330 T DE 08771330T DE 08771330 T1 DE08771330 T1 DE 08771330T1
Authority
DE
Germany
Prior art keywords
optical probe
probe
solution
optical
cleaning
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE08771330T
Other languages
German (de)
English (en)
Inventor
Laurence Dwayne Needham Chin
Archibald Wareham Williams
Martin Lakeville Schwalm
Brett Andrew Feeney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Varian Inc
Original Assignee
Varian Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Varian Inc filed Critical Varian Inc
Publication of DE08771330T1 publication Critical patent/DE08771330T1/de
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/15Preventing contamination of the components of the optical system or obstruction of the light path
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/85Investigating moving fluids or granular solids
    • G01N21/8507Probe photometers, i.e. with optical measuring part dipped into fluid sample
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • G01N2013/006Dissolution of tablets or the like
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/15Preventing contamination of the components of the optical system or obstruction of the light path
    • G01N2021/154Ultrasonic cleaning
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/85Investigating moving fluids or granular solids
    • G01N21/8507Probe photometers, i.e. with optical measuring part dipped into fluid sample
    • G01N2021/8528Immerged light conductor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274Calibration, base line adjustment, drift correction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Optical Measuring Cells (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
DE08771330T 2007-06-20 2008-06-18 Vorrichtung und verfahren für automatische einführung, blasenentfernung, reinigung und kalibrierung einer spektralsonde während einer auflösungsprüfung Pending DE08771330T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US93625707P 2007-06-20 2007-06-20
US936257P 2007-06-20
PCT/US2008/067302 WO2008157584A2 (en) 2007-06-20 2008-06-18 Apparatus and methods for automatic insertion, debubbling, cleaning and calibration of a spectral probe during dissolution testing

Publications (1)

Publication Number Publication Date
DE08771330T1 true DE08771330T1 (de) 2010-09-30

Family

ID=40156950

Family Applications (1)

Application Number Title Priority Date Filing Date
DE08771330T Pending DE08771330T1 (de) 2007-06-20 2008-06-18 Vorrichtung und verfahren für automatische einführung, blasenentfernung, reinigung und kalibrierung einer spektralsonde während einer auflösungsprüfung

Country Status (8)

Country Link
EP (1) EP2162725A4 (pt)
JP (1) JP2010530542A (pt)
KR (1) KR20100023963A (pt)
CN (1) CN101688825A (pt)
BR (1) BRPI0813135A2 (pt)
DE (1) DE08771330T1 (pt)
MX (1) MX2009013778A (pt)
WO (1) WO2008157584A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010094341A1 (de) * 2009-02-20 2010-08-26 Erweka Gmbh Zerfallszeitmessgerät
JP5861010B2 (ja) * 2013-12-11 2016-02-16 オリンパス株式会社 校正器および校正装置
CN104492364A (zh) * 2014-12-29 2015-04-08 常州市龙道电子商务有限公司 具有旋转消泡装置的反应釜
CN104492365A (zh) * 2014-12-29 2015-04-08 常州市龙道电子商务有限公司 反应釜
EP3176565B1 (en) * 2015-12-04 2021-04-28 Atten2 Advanced Monitoring Technologies S.L.U. Fluid monitoring system based on near-infrared spectroscopy
US9945830B2 (en) * 2016-01-21 2018-04-17 Rosemount Inc. Standard solution with cleaning reagent for wet chemistry analyzer
CN113388488B (zh) * 2020-03-12 2023-09-29 迪必尔智能科技(深圳)有限公司 一种可高温灭菌的探针式生物量在线检测装置
JP7446614B2 (ja) * 2020-10-23 2024-03-11 富山産業株式会社 崩壊試験バスケット及び崩壊検出装置
WO2024091881A1 (en) * 2022-10-24 2024-05-02 Thermo Scientific Portable Analytical Instruments Inc. Self centering vial holder for immersion probes

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH636200A5 (en) * 1979-03-20 1983-05-13 Zellweger Uster Ag Method and device for removing gas bubbles and other deposits from cuvettes (cells)
US6174497B1 (en) * 1997-06-04 2001-01-16 Euro-Celtique, S.A. Detection systems and methods for predicting the dissolution curve of a drug from a pharmaceutical dosage form
US6762841B1 (en) * 2000-02-22 2004-07-13 Spectraalliance, Inc. Method of performing spectral analysis in a pharmaceutical dissolution process
AU2001240121B2 (en) * 2000-03-10 2005-06-23 Textron Systems Corporation Optical probes and methods for spectral analysis
US6580506B2 (en) * 2001-02-10 2003-06-17 Leap Technologies, Inc. Fiber optic probes apparatus for spectrophotometry
US6962674B2 (en) * 2001-02-28 2005-11-08 Varian, Inc. Dissolution test apparatus
US6764651B2 (en) * 2001-11-07 2004-07-20 Varian, Inc. Fiber-optic dissolution systems, devices, and methods
WO2003098199A1 (en) * 2002-05-17 2003-11-27 Delphian Technology, Inc. In situ methods for measuring the release of a substance from a dosage form

Also Published As

Publication number Publication date
BRPI0813135A2 (pt) 2014-12-23
WO2008157584A2 (en) 2008-12-24
CN101688825A (zh) 2010-03-31
KR20100023963A (ko) 2010-03-04
EP2162725A4 (en) 2010-06-09
JP2010530542A (ja) 2010-09-09
WO2008157584A3 (en) 2009-03-05
MX2009013778A (es) 2010-02-17
EP2162725A2 (en) 2010-03-17

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