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DD138547A5 - Verfahren zur herstellung von 2-guanidinomethyl-indolinen - Google Patents

Verfahren zur herstellung von 2-guanidinomethyl-indolinen

Info

Publication number
DD138547A5
DD138547A5 DD78207604A DD20760478A DD138547A5 DD 138547 A5 DD138547 A5 DD 138547A5 DD 78207604 A DD78207604 A DD 78207604A DD 20760478 A DD20760478 A DD 20760478A DD 138547 A5 DD138547 A5 DD 138547A5
Authority
DD
German Democratic Republic
Prior art keywords
guanidinomethyl
indolines
preparation
guanidinomethyl indolines
Prior art date
Application number
DD78207604A
Other languages
German (de)
English (en)
Inventor
Rochus Jonas
Hans-Jochen Schliep
Ernst Schorscher
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of DD138547A5 publication Critical patent/DD138547A5/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DD78207604A 1977-09-03 1978-09-01 Verfahren zur herstellung von 2-guanidinomethyl-indolinen DD138547A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772739723 DE2739723A1 (de) 1977-09-03 1977-09-03 2-guanidinomethyl-indoline und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
DD138547A5 true DD138547A5 (de) 1979-11-07

Family

ID=6018021

Family Applications (1)

Application Number Title Priority Date Filing Date
DD78207604A DD138547A5 (de) 1977-09-03 1978-09-01 Verfahren zur herstellung von 2-guanidinomethyl-indolinen

Country Status (10)

Country Link
US (1) US4260628A (es)
EP (1) EP0001546A1 (es)
JP (1) JPS5446778A (es)
AU (1) AU3939978A (es)
DD (1) DD138547A5 (es)
DE (1) DE2739723A1 (es)
ES (2) ES473038A1 (es)
IL (1) IL55460A (es)
IT (1) IT1106131B (es)
ZA (1) ZA785005B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963689A (en) * 1989-05-19 1990-10-16 Pfizer Inc. Heterocyclicguanidines as 5HT3 antagonists
FR2822463B1 (fr) 2001-03-21 2004-07-30 Lipha Derives bicycliques de guanidines et leurs applications en therapeutique
US9670149B2 (en) * 2013-06-17 2017-06-06 3M Innovative Properties Company Process for preparing guanidino-functional monomers
CN113968855A (zh) * 2020-07-24 2022-01-25 中国科学院上海药物研究所 一种治疗血栓性疾病的化合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3093632A (en) * 1961-02-02 1963-06-11 Ciba Geigy Corp Dibenzpolymethylenimino-alkylene-guanidines
US3317560A (en) * 1963-01-03 1967-05-02 Philips Corp Indol-3-yl alkylguanidine derivatives
US3354174A (en) * 1964-02-19 1967-11-21 Sterling Drug Inc 1-and 2-benzimidazolyl-lower-alkylamidoximes, amidines-, and guanidines
US3428653A (en) * 1965-06-28 1969-02-18 Sterling Drug Inc 3-indolylmethylguanidine
BE792724A (fr) * 1971-12-16 1973-06-14 Merck Patent Gmbh Derives de pyrazinoindole et leur procede de preparation
HU170404B (es) * 1975-02-27 1977-06-28

Also Published As

Publication number Publication date
ES473038A1 (es) 1979-10-16
IT1106131B (it) 1985-11-11
IL55460A (en) 1981-03-31
DE2739723A1 (de) 1979-03-08
JPS5446778A (en) 1979-04-12
EP0001546A1 (de) 1979-05-02
ZA785005B (en) 1979-08-29
IT7850946A0 (it) 1978-09-01
ES480765A1 (es) 1979-11-16
IL55460A0 (en) 1978-10-31
US4260628A (en) 1981-04-07
AU3939978A (en) 1980-03-06

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