CZ418597A3 - 1,6-disubstituované izochromany pro léčbu bolestí hlavy při migréně - Google Patents
1,6-disubstituované izochromany pro léčbu bolestí hlavy při migréně Download PDFInfo
- Publication number
- CZ418597A3 CZ418597A3 CZ974185A CZ418597A CZ418597A3 CZ 418597 A3 CZ418597 A3 CZ 418597A3 CZ 974185 A CZ974185 A CZ 974185A CZ 418597 A CZ418597 A CZ 418597A CZ 418597 A3 CZ418597 A3 CZ 418597A3
- Authority
- CZ
- Czechia
- Prior art keywords
- defined above
- ethyl
- isochroman
- alkyl
- piperazinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/76—Benzo[c]pyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74195P | 1995-06-30 | 1995-06-30 | |
| US1123496P | 1996-02-06 | 1996-02-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CZ418597A3 true CZ418597A3 (cs) | 1998-06-17 |
Family
ID=26668092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CZ974185A CZ418597A3 (cs) | 1995-06-30 | 1996-06-07 | 1,6-disubstituované izochromany pro léčbu bolestí hlavy při migréně |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0836599A1 (es) |
| JP (1) | JPH11509532A (es) |
| AU (1) | AU6252296A (es) |
| BR (1) | BR9609631A (es) |
| CA (1) | CA2225282A1 (es) |
| CZ (1) | CZ418597A3 (es) |
| FI (1) | FI974640A0 (es) |
| MX (1) | MX9710260A (es) |
| NO (1) | NO976112L (es) |
| PL (1) | PL324319A1 (es) |
| SK (1) | SK164297A3 (es) |
| WO (1) | WO1997002259A1 (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2370270A (en) * | 2000-12-20 | 2002-06-26 | Lilly Co Eli | Pharmaceutical compounds |
| GB0130339D0 (en) * | 2001-12-19 | 2002-02-06 | Lilly Co Eli | Isochroman compounds |
| US7335660B2 (en) | 2001-12-19 | 2008-02-26 | Eli Lilly And Company | Isochroman compounds for treatment of CNS disorders |
| US7110576B2 (en) | 2002-12-30 | 2006-09-19 | Pitney Bowes Inc. | System and method for authenticating a mailpiece sender |
| BRPI0510642A (pt) | 2004-05-05 | 2007-11-20 | Hoffmann La Roche | arilsulfonil benzodioxanos úteis para modulação do receptor de 5-ht6, do receptor de 5ht2a ou ambos |
| EP1831189B1 (en) | 2004-12-21 | 2009-11-11 | F. Hoffmann-Roche AG | Tetralin and indane derivatives and uses thereof |
| EP1831203A1 (en) | 2004-12-21 | 2007-09-12 | F. Hoffmann-Roche AG | Chroman derivatives and uses thereof in the treatment of cns disorders |
| KR20070088798A (ko) | 2004-12-21 | 2007-08-29 | 에프. 호프만-라 로슈 아게 | 크로만 유도체 및 그의 5-ht 수용체 리간드로서의 용도 |
| BRPI0515860B8 (pt) | 2004-12-21 | 2021-05-25 | Hoffmann La Roche | derivados de tetralin e indano, seus usos, e composição farmacêutica |
| CN101111472A (zh) | 2004-12-21 | 2008-01-23 | 弗·哈夫曼-拉罗切有限公司 | 1,2,3,4-四氢化萘和茚满衍生物及其作为5-ht拮抗剂的用途 |
| NZ567285A (en) | 2005-11-03 | 2010-06-25 | Hoffmann La Roche | Arylsulfonylchromans as 5-HT6 inhibitors indolylmaleimide derivatives as protein kinase inhibitors |
| BRPI0713736A2 (pt) | 2006-06-20 | 2014-11-18 | Hoffmann La Roche | Derivados de tetralina e indano e emprego destes |
| MX2008015510A (es) | 2006-06-20 | 2008-12-18 | Hoffmann La Roche | Derivados de arilsulfonamidiltetralina y usos de los mismos. |
| WO2007147763A1 (en) | 2006-06-20 | 2007-12-27 | F. Hoffmann-La Roche Ag | Arylsulfonyl naphthalene derivatives and uses thereof |
| KR20110125258A (ko) * | 2009-03-05 | 2011-11-18 | 스미또모 가가꾸 가부시끼가이샤 | 할로겐 치환 벤젠디메탄올의 제조 방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1552004A (en) * | 1976-05-26 | 1979-09-05 | Takeda Chemical Industries Ltd | Isochroman derivatives |
| ES2133714T3 (es) * | 1993-12-28 | 1999-09-16 | Upjohn Co | Compuestos heterociclicos para el tratamiento de trastornos del snc y cardiovasculares. |
-
1996
- 1996-06-07 AU AU62522/96A patent/AU6252296A/en not_active Abandoned
- 1996-06-07 PL PL96324319A patent/PL324319A1/xx unknown
- 1996-06-07 CA CA002225282A patent/CA2225282A1/en not_active Abandoned
- 1996-06-07 SK SK1642-97A patent/SK164297A3/sk unknown
- 1996-06-07 FI FI974640A patent/FI974640A0/fi unknown
- 1996-06-07 JP JP9505135A patent/JPH11509532A/ja active Pending
- 1996-06-07 BR BR9609631A patent/BR9609631A/pt not_active Application Discontinuation
- 1996-06-07 MX MX9710260A patent/MX9710260A/es unknown
- 1996-06-07 EP EP96921264A patent/EP0836599A1/en not_active Withdrawn
- 1996-06-07 WO PCT/US1996/008681 patent/WO1997002259A1/en not_active Ceased
- 1996-06-07 CZ CZ974185A patent/CZ418597A3/cs unknown
-
1997
- 1997-12-29 NO NO976112A patent/NO976112L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH11509532A (ja) | 1999-08-24 |
| EP0836599A1 (en) | 1998-04-22 |
| MX9710260A (es) | 1998-03-29 |
| FI974640A7 (fi) | 1997-12-30 |
| AU6252296A (en) | 1997-02-05 |
| WO1997002259A1 (en) | 1997-01-23 |
| FI974640L (fi) | 1997-12-30 |
| PL324319A1 (en) | 1998-05-25 |
| BR9609631A (pt) | 1999-03-02 |
| CA2225282A1 (en) | 1997-01-23 |
| SK164297A3 (en) | 1998-09-09 |
| NO976112D0 (no) | 1997-12-29 |
| FI974640A0 (fi) | 1997-12-30 |
| NO976112L (no) | 1998-03-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2013254657B2 (en) | Novel compounds | |
| TW536537B (en) | Benzoxazine antimicrobial agents | |
| AU701452B2 (en) | Benzylpiperidines and piperazines as muscarinic antagonists | |
| AU701420B2 (en) | Novel piperazides derived from arylpiperazine, processes for their preparation, their use as medicaments and pharmaceutical compositions comprising them | |
| CZ418597A3 (cs) | 1,6-disubstituované izochromany pro léčbu bolestí hlavy při migréně | |
| NL1028968C2 (nl) | 3- of 4-monogesubstitueerde fenol- en thiofenolderivaten die als H3-liganden bruikbaar zijn. | |
| JPWO2005037269A1 (ja) | 新規ピペリジン誘導体 | |
| CN104470913B (zh) | 用于制造羟基化的环戊基嘧啶化合物的方法 | |
| AU684874B2 (en) | Heterocyclic compounds for the treatment of cns and cardiovascular disorders | |
| HK1211577A1 (en) | Processes for the preparation of (s)-3-4- ((4-(morpholinomethyl) benzyl)oxy)-1-oxoisoindolin-2-yl) piperidine-2,6-dione and pharmaceutically acceptable forms thereof | |
| JP3035356B2 (ja) | ピロリジニルヒドロキサム酸化合物及びその製造方法 | |
| JP2006527769A (ja) | Cb1モジュレーターとしての2,3位置換5,6−ジアリール−ピラジン誘導体 | |
| EP1940823A2 (fr) | Dérivés de la 1-amino-phtalazine substituee, leur préparation et leur application en thérapeutique | |
| HU225747B1 (en) | New benzenesulphonamide compounds, their preparation thereof and pharmaceutical compositions containing them | |
| US20040034036A1 (en) | N-(3,5-dichloro-2-methoxyphenyl)-4-methoxy-3-piperazin-1-yl-benzenesulfonamide | |
| KR20150065190A (ko) | 피라진 유도체 | |
| OA11235A (en) | Quatenary ammonium compounds as tachykinin antagonists | |
| MXPA04012345A (es) | Derivados de pirimidina 2,5-substituida como antagonistas ix del receptor ccr-3. | |
| AU707950B2 (en) | Heterocyclic compounds for treating myocardial ischemia | |
| JPH06306025A (ja) | ジアリールアルカン誘導体 | |
| KR19990028550A (ko) | 편두통 치료용의 1,6-이치환된 이소크로만 | |
| US12338236B2 (en) | Benzoisothiazole and benzoisoxazole compounds for the treatment of mental disorders | |
| KR940009533B1 (ko) | 헥사하이드로디벤조디옥산에서 유도된 암모늄염의 제조방법 | |
| Gao | Design, synthesis and evaluation of novel muscarinic ligands | |
| JPH08231507A (ja) | ビフェニル誘導体 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PD00 | Pending as of 2000-06-30 in czech republic |