CZ20011753A3 - Semihydrochlorid kyseliny 8-kyano-1-cyklopropyl-7-(1S,6S-2,8-diazabicyklo[4,3,0]nonan-8yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolinkarboxylové, způsob přípravy a jeho použití ve směsích s antibakteriálními účinky - Google Patents

Semihydrochlorid kyseliny 8-kyano-1-cyklopropyl-7-(1S,6S-2,8-diazabicyklo[4,3,0]nonan-8yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolinkarboxylové, způsob přípravy a jeho použití ve směsích s antibakteriálními účinky

Info

Publication number: CZ20011753A3
Authority: CZ; Czechia
Prior art keywords: semihydrochloride; nonan; diazabicyclo; cyclopropyl; dihydro
Prior art date: 1998-11-25

Application number

CZ20011753A

Other languages

English (en)

Other versions

CZ300058B6 (cs

Inventor

Thomas Himmler

Hubert Rast

Original Assignee

Bayer Aktiengesellschaft

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-25

Filing date

1999-11-15

Publication date

2001-09-12

1999-11-15 Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft

2001-09-12 Publication of CZ20011753A3 publication Critical patent/CZ20011753A3/cs

2009-01-21 Publication of CZ300058B6 publication Critical patent/CZ300058B6/cs

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CZ20011753A 1998-11-25 1999-11-15 Semihydrochlorid kyseliny 8-kyano-1-cyklopropyl-7-(1S,6S-2,8-diazabicyklo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolinkarboxylové, zpusob prípravy a jeho použití ve smesích s antibakteriálními úcinky CZ300058B6 (cs)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19854357A DE19854357A1 (de)	1998-11-25	1998-11-25	Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure

Publications (2)

Publication Number	Publication Date
CZ20011753A3 true CZ20011753A3 (cs)	2001-09-12
CZ300058B6 CZ300058B6 (cs)	2009-01-21

Family

ID=7888961

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CZ20011753A CZ300058B6 (cs)	1998-11-25	1999-11-15	Semihydrochlorid kyseliny 8-kyano-1-cyklopropyl-7-(1S,6S-2,8-diazabicyklo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolinkarboxylové, zpusob prípravy a jeho použití ve smesích s antibakteriálními úcinky

Country Status (28)

Country	Link
US (1)	US6995170B1 (cs)
EP (1)	EP1133495B1 (cs)
JP (1)	JP2002530408A (cs)
KR (1)	KR100740956B1 (cs)
CN (1)	CN1176921C (cs)
AR (1)	AR023709A1 (cs)
AT (1)	ATE225790T1 (cs)
AU (1)	AU759769B2 (cs)
BR (1)	BR9915684A (cs)
CA (1)	CA2351714C (cs)
CZ (1)	CZ300058B6 (cs)
DE (2)	DE19854357A1 (cs)
DK (1)	DK1133495T3 (cs)
ES (1)	ES2181488T3 (cs)
HK (1)	HK1042704B (cs)
HU (1)	HUP0104367A3 (cs)
IL (2)	IL142837A0 (cs)
NO (1)	NO318053B1 (cs)
NZ (1)	NZ511863A (cs)
PL (1)	PL196508B1 (cs)
PT (1)	PT1133495E (cs)
RU (1)	RU2242475C2 (cs)
SK (1)	SK285561B6 (cs)
TR (1)	TR200101443T2 (cs)
TW (1)	TWI234565B (cs)
UA (1)	UA67875C2 (cs)
WO (1)	WO2000031077A1 (cs)
ZA (1)	ZA013317B (cs)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19854357A1 (de) *	1998-11-25	2000-05-31	Bayer Ag	Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE10224086A1 (de) *	2002-05-31	2003-12-11	Bayer Ag	Pharmazeutische Zubereitungen zur oralen Anwendung enthaltend wirkstoffbeladene Ionentauscherharze sowie strukturviskose Gelbildner als Verdicker
DE102004015981A1 (de) *	2004-04-01	2005-10-20	Bayer Healthcare Ag	Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE102006049520A1 (de) *	2006-10-20	2008-04-24	Bayer Healthcare Ag	Verfahren zur Herstellung von Pradofloxacin
RU2019128568A (ru)	2017-02-13	2021-03-15	Байер Энимэл Хельс ГмбХ	Жидкая композиция, содержащая прадофлоксацин
CN116813614A (zh) *	2023-05-31	2023-09-29	天津大学	一种盐酸普拉沙星二水合物晶体及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3906365A1 (de) *	1988-07-15	1990-01-18	Bayer Ag	7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
DE3910663A1 (de) *	1989-04-03	1990-10-04	Bayer Ag	5-alkylchinoloncarbonsaeuren
DE4120646A1 (de) *	1991-06-22	1992-12-24	Bayer Ag	7-isoindolinyl-chinolon- und naphthyridoncarbonsaeure-derivate
DE19546249A1 (de) *	1995-12-12	1997-06-19	Bayer Ag	Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
EP0882049B1 (de) *	1996-02-23	2002-11-20	Bayer Ag	Gegebenenfalls substituierte 8-cyan-1-cyclopropyl-7-(2,8-diazabicyclo- 4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre derivate
DE19633805A1 (de) *	1996-02-23	1997-08-28	Bayer Ag	Gegenenenfalls substituierte 8-Cyan-l-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre Derivate
DE19854357A1 (de) *	1998-11-25	2000-05-31	Bayer Ag	Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure

1998
- 1998-11-25 DE DE19854357A patent/DE19854357A1/de not_active Withdrawn
1999
- 1999-11-15 WO PCT/EP1999/008778 patent/WO2000031077A1/de not_active Ceased
- 1999-11-15 DE DE59903063T patent/DE59903063D1/de not_active Expired - Lifetime
- 1999-11-15 NZ NZ511863A patent/NZ511863A/en not_active IP Right Cessation
- 1999-11-15 US US09/856,571 patent/US6995170B1/en not_active Expired - Fee Related
- 1999-11-15 PL PL347799A patent/PL196508B1/pl not_active IP Right Cessation
- 1999-11-15 AU AU12716/00A patent/AU759769B2/en not_active Ceased
- 1999-11-15 PT PT99955995T patent/PT1133495E/pt unknown
- 1999-11-15 TR TR2001/01443T patent/TR200101443T2/xx unknown
- 1999-11-15 CA CA2351714A patent/CA2351714C/en not_active Expired - Fee Related
- 1999-11-15 UA UA2001064427A patent/UA67875C2/uk unknown
- 1999-11-15 IL IL14283799A patent/IL142837A0/xx active IP Right Grant
- 1999-11-15 EP EP99955995A patent/EP1133495B1/de not_active Expired - Lifetime
- 1999-11-15 JP JP2000583905A patent/JP2002530408A/ja active Pending
- 1999-11-15 BR BR9915684-9A patent/BR9915684A/pt not_active Application Discontinuation
- 1999-11-15 KR KR1020017005875A patent/KR100740956B1/ko not_active Expired - Fee Related
- 1999-11-15 SK SK684-2001A patent/SK285561B6/sk not_active IP Right Cessation
- 1999-11-15 ES ES99955995T patent/ES2181488T3/es not_active Expired - Lifetime
- 1999-11-15 HK HK02104455.8A patent/HK1042704B/zh not_active IP Right Cessation
- 1999-11-15 DK DK99955995T patent/DK1133495T3/da active
- 1999-11-15 TW TW088119809A patent/TWI234565B/zh not_active IP Right Cessation
- 1999-11-15 CN CNB998136743A patent/CN1176921C/zh not_active Expired - Fee Related
- 1999-11-15 HU HU0104367A patent/HUP0104367A3/hu unknown
- 1999-11-15 RU RU2001117528/04A patent/RU2242475C2/ru not_active IP Right Cessation
- 1999-11-15 CZ CZ20011753A patent/CZ300058B6/cs not_active IP Right Cessation
- 1999-11-15 AT AT99955995T patent/ATE225790T1/de not_active IP Right Cessation
- 1999-11-22 AR ARP990105939A patent/AR023709A1/es unknown
2001
- 2001-04-24 ZA ZA2001/03317A patent/ZA013317B/en unknown
- 2001-04-27 IL IL142837A patent/IL142837A/en not_active IP Right Cessation
- 2001-05-23 NO NO20012532A patent/NO318053B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO318053B1 (no)	2005-01-24
DE19854357A1 (de)	2000-05-31
EP1133495B1 (de)	2002-10-09
RU2242475C2 (ru)	2004-12-20
TWI234565B (en)	2005-06-21
KR20010075694A (ko)	2001-08-09
HUP0104367A3 (en)	2002-12-28
TR200101443T2 (tr)	2001-09-21
IL142837A (en)	2006-08-01
BR9915684A (pt)	2001-08-14
CN1176921C (zh)	2004-11-24
ES2181488T3 (es)	2003-02-16
CA2351714A1 (en)	2000-06-02
PL196508B1 (pl)	2008-01-31
UA67875C2 (uk)	2004-07-15
DE59903063D1 (de)	2002-11-14
PL347799A1 (en)	2002-04-22
HUP0104367A2 (hu)	2002-02-28
JP2002530408A (ja)	2002-09-17
ZA013317B (en)	2002-06-26
KR100740956B1 (ko)	2007-07-19
NO20012532D0 (no)	2001-05-23
AU1271600A (en)	2000-06-13
PT1133495E (pt)	2003-02-28
NO20012532L (no)	2001-07-02
CN1328557A (zh)	2001-12-26
SK6842001A3 (en)	2001-12-03
SK285561B6 (sk)	2007-03-01
WO2000031077A1 (de)	2000-06-02
HK1042704A1 (en)	2002-08-23
ATE225790T1 (de)	2002-10-15
US6995170B1 (en)	2006-02-07
NZ511863A (en)	2003-05-30
EP1133495A1 (de)	2001-09-19
HK1042704B (zh)	2005-09-09
CA2351714C (en)	2010-06-15
AR023709A1 (es)	2002-09-04
AU759769B2 (en)	2003-05-01
DK1133495T3 (da)	2003-02-10
IL142837A0 (en)	2002-03-10
CZ300058B6 (cs)	2009-01-21

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Legal Events

Date	Code	Title	Description
2011-06-08	MM4A	Patent lapsed due to non-payment of fee	Effective date: 20101115