CY1682A - 3-aryloxy-3-substituted propanamines - Google Patents
3-aryloxy-3-substituted propanaminesInfo
- Publication number
- CY1682A CY1682A CY1682A CY168293A CY1682A CY 1682 A CY1682 A CY 1682A CY 1682 A CY1682 A CY 1682A CY 168293 A CY168293 A CY 168293A CY 1682 A CY1682 A CY 1682A
- Authority
- CY
- Cyprus
- Prior art keywords
- aryloxy
- substituted propanamines
- propanamines
- substituted
- Prior art date
Links
- WGYKZJWCGVVSQN-UHFFFAOYSA-N propylamine Chemical class CCCN WGYKZJWCGVVSQN-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94512286A | 1986-12-22 | 1986-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1682A true CY1682A (en) | 1993-10-10 |
Family
ID=25482649
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY1682A CY1682A (en) | 1986-12-22 | 1993-10-10 | 3-aryloxy-3-substituted propanamines |
| CY200500001C CY2005001I1 (el) | 1986-12-22 | 2005-01-27 | 3-aryloxy-3-substituted propanamines |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY200500001C CY2005001I1 (el) | 1986-12-22 | 2005-01-27 | 3-aryloxy-3-substituted propanamines |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP0273658B1 (xx) |
| JP (1) | JP2549681B2 (xx) |
| KR (2) | KR880007433A (xx) |
| CN (1) | CN1019113B (xx) |
| AR (1) | AR243868A1 (xx) |
| AT (1) | ATE57924T1 (xx) |
| AU (1) | AU591007B2 (xx) |
| CA (1) | CA1302421C (xx) |
| CY (2) | CY1682A (xx) |
| DE (3) | DE122005000002I1 (xx) |
| DK (1) | DK174599B1 (xx) |
| EG (1) | EG18230A (xx) |
| ES (1) | ES2019949B3 (xx) |
| GR (1) | GR3001207T3 (xx) |
| HK (1) | HK69693A (xx) |
| HU (1) | HU206309B (xx) |
| IE (1) | IE873449L (xx) |
| IL (1) | IL84863A (xx) |
| LU (1) | LU91131I2 (xx) |
| MX (1) | MX9845A (xx) |
| NL (1) | NL300171I2 (xx) |
| NZ (1) | NZ222980A (xx) |
| PH (1) | PH26556A (xx) |
| PT (1) | PT86389B (xx) |
| SG (1) | SG114992G (xx) |
| SU (1) | SU1598865A3 (xx) |
| ZA (1) | ZA879472B (xx) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4902710A (en) * | 1988-12-14 | 1990-02-20 | Eli Lilly And Company | Serotonin and norepinephrine uptake inhibitors |
| IL98108A0 (en) * | 1990-05-17 | 1992-06-21 | Lilly Co Eli | Chiral synthesis of 1-aryl-3-aminopropan-1-ols |
| EP0571685A1 (en) * | 1992-05-27 | 1993-12-01 | Novo Nordisk A/S | Aryloxyheteroarylpropylamines, their preparation and use |
| US5362886A (en) * | 1993-10-12 | 1994-11-08 | Eli Lilly And Company | Asymmetric synthesis |
| TW344661B (en) * | 1993-11-24 | 1998-11-11 | Lilly Co Eli | Pharmaceutical composition for treatment of incontinence |
| GB0004153D0 (en) | 2000-02-23 | 2000-04-12 | Astrazeneca Uk Ltd | Novel use |
| GB0004149D0 (en) | 2000-02-23 | 2000-04-12 | Astrazeneca Uk Ltd | Novel compounds |
| GB0004151D0 (en) | 2000-02-23 | 2000-04-12 | Astrazeneca Uk Ltd | Novel use |
| GB0004152D0 (en) * | 2000-02-23 | 2000-04-12 | Astrazeneca Uk Ltd | Novel compounds |
| CA2452347A1 (en) * | 2001-07-31 | 2003-02-13 | Pharmacia & Upjohn Company | Treatment of chronic pain with 3-aryloxy-3-phenylpropanamines |
| SE0102640D0 (sv) | 2001-07-31 | 2001-07-31 | Astrazeneca Ab | Novel compounds |
| CA2477088A1 (en) | 2002-02-22 | 2003-10-02 | New River Pharmaceuticals Inc. | Active agent delivery systems and methods for protecting and administering active agents |
| US7659409B2 (en) | 2002-03-19 | 2010-02-09 | Mitsubishi Chemical Corporation | 3-Hydroxy-3-(2-thienyl) propionamides and production method thereof, and production method of 3-amino-1-(2-thienyl)-1-propanols using the same |
| EP1486493A4 (en) * | 2002-03-19 | 2007-04-04 | Mitsubishi Chem Corp | 3-HYDROXY-3- (2-THIENYL) PROPIONIC ACID AMID COMPOUND, METHOD FOR THE PRODUCTION THEREOF AND METHOD FOR PRODUCING A 3-AMINO-1- (2-THIENYL) -1-PROPANOL COMPOUND THEREFOR |
| JPWO2003097632A1 (ja) * | 2002-05-20 | 2005-09-15 | 三菱レイヨン株式会社 | プロパノールアミン誘導体、及び3−n−メチルアミノ−1−(2−チエニル)−1−プロパノールの製造方法、並びにプロパノールアミン誘導体の製造方法 |
| DE10235206A1 (de) * | 2002-08-01 | 2004-02-19 | Basf Ag | Verfahren zur Herstellung von (S)-3-Methylmino-1-(thien-2-yl)propan-1-ol |
| GB0220581D0 (en) | 2002-09-04 | 2002-10-09 | Novartis Ag | Organic Compound |
| GB0229583D0 (en) * | 2002-12-19 | 2003-01-22 | Cipla Ltd | A process for preparing duloxetine and intermediates for use therein |
| DE10302595A1 (de) | 2003-01-22 | 2004-07-29 | Basf Ag | 3-Methylamino-1-(2-thienyl)-1-proganon, seine Herstellung und Verwendung |
| DE10345772A1 (de) | 2003-10-01 | 2005-04-21 | Basf Ag | Verfahren zur Herstellung von 3-Methylamino-1-(thien-2-yl)-propan-1-ol |
| DE102004004719A1 (de) | 2004-01-29 | 2005-08-18 | Basf Ag | Verfahren zur Herstellung von enantiomerenreinen Aminoalkoholen |
| CA2556891C (en) * | 2004-02-19 | 2012-12-18 | Lonza Ag | Process for the preparation of enantiomerically pure 1-substituted-3-aminoalcohols |
| CA2556063A1 (en) * | 2004-02-20 | 2005-09-09 | Pharmacia & Upjohn Company Llc | Method for the preparation of aryl ethers |
| DE102004022686A1 (de) | 2004-05-05 | 2005-11-24 | Basf Ag | Verfahren zur Herstellung optisch aktiver Alkohole |
| GB0410470D0 (en) * | 2004-05-11 | 2004-06-16 | Cipla Ltd | Pharmaceutical compound and polymorphs thereof |
| AR049401A1 (es) | 2004-06-18 | 2006-07-26 | Novartis Ag | Aza-biciclononanos |
| GB0415746D0 (en) | 2004-07-14 | 2004-08-18 | Novartis Ag | Organic compounds |
| WO2006021564A1 (en) * | 2004-08-26 | 2006-03-02 | Neurosearch A/S | Novel substituted aryloxy alkylamines and their use as monoamine neurotransmitter re-uptake inhibitors |
| US20060194869A1 (en) * | 2004-12-23 | 2006-08-31 | Santiago Ini | Process for preparing pharmaceutically acceptable salts of duloxetine and intermediates thereof |
| CA2599475A1 (en) | 2005-03-14 | 2006-09-21 | Teva Pharmaceutical Industries Ltd. | Pure duloxetine hydrochloride |
| GB0507298D0 (en) | 2005-04-11 | 2005-05-18 | Novartis Ag | Organic compounds |
| JP5258561B2 (ja) | 2005-07-15 | 2013-08-07 | アルバニー モレキュラー リサーチ, インコーポレイテッド | アリール置換およびヘテロアリール置換テトラヒドロベンズアゼピンならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するためのその使用 |
| DE102005044736A1 (de) | 2005-09-19 | 2007-03-22 | Basf Ag | Neue Dehydrogenasen, deren Derivate und ein Verfahren zur Herstellung von optisch aktiven Alkanolen |
| EP1838692A2 (en) * | 2005-09-22 | 2007-10-03 | Teva Pharmaceutical Industries Ltd | Dnt-maleate and methods of preparation thereof |
| ITMI20051970A1 (it) | 2005-10-18 | 2007-04-19 | Solmag S P A | Processo per la preparazione di eteri misti derivanti dall'inaftolo e intermedi di forme cristalline definite di + e - duloxetina |
| ES2329413T3 (es) * | 2005-11-30 | 2009-11-25 | F. Hoffmann-La Roche Ag | 3-amino-2-arilpropil azaindoles y usos de los mismos. |
| EP1863782A1 (en) | 2005-12-05 | 2007-12-12 | Teva Pharmaceutical Industries Ltd. | 2-(n-methyl-propanamine)-3-(2-naphtol) thiophene, an imputity of duloxetine hydrochloride |
| GB0525673D0 (en) | 2005-12-16 | 2006-01-25 | Novartis Ag | Organic compounds |
| GB0525672D0 (en) | 2005-12-16 | 2006-01-25 | Novartis Ag | Organic compounds |
| DE102005062662A1 (de) | 2005-12-23 | 2007-06-28 | Basf Ag | Verfahren zur Herstellung optisch aktiver Alkohole |
| DE102005062661A1 (de) | 2005-12-23 | 2007-08-16 | Basf Ag | Verfahren zur Herstellung von optisch aktivem (1S)-3-Chlor-(-thien-2-yl)-propan-1-ol |
| CZ299270B6 (cs) | 2006-01-04 | 2008-06-04 | Zentiva, A. S. | Zpusob výroby hydrochloridu (S)-N-methyl-3-(1-naftyloxy)-3-(2-thienyl)propylaminu |
| US8362279B2 (en) | 2006-01-06 | 2013-01-29 | Msn Laboratories Limited | Process for pure duloxetine hydrochloride |
| WO2008077645A1 (en) | 2006-12-22 | 2008-07-03 | Synthon B.V. | Process for making duloxetine and related compounds |
| JP5543958B2 (ja) * | 2008-04-11 | 2014-07-09 | ウェルズ ファーゴ バンク ナショナル アソシエイション | オリゴマー−アリールオキシ置換プロパンアミンコンジュゲート |
| EP2133072A1 (en) | 2008-06-13 | 2009-12-16 | KRKA, D.D., Novo Mesto | Gastro-resistant pharmaceutical oral compositions comprising duloxetine or its pharmaceutically acceptable derivatives |
| CN101613347B (zh) | 2008-06-23 | 2012-07-04 | 中国人民解放军军事医学科学院毒物药物研究所 | 胺类化合物及其医药用途 |
| HU230480B1 (hu) * | 2008-07-25 | 2016-07-28 | Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság | Eljárás N-metil-ariloxi-propánamin származékok előállítására |
| US8288141B2 (en) | 2008-08-27 | 2012-10-16 | Codexis, Inc. | Ketoreductase polypeptides for the production of 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine |
| EP2329013B1 (en) | 2008-08-27 | 2015-10-28 | Codexis, Inc. | Ketoreductase polypeptides for the production of a 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine |
| EP2429293B1 (en) | 2009-05-12 | 2014-10-29 | Bristol-Myers Squibb Company | CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF |
| DK2429296T3 (en) | 2009-05-12 | 2018-03-12 | Albany Molecular Res Inc | 7 - ([1,2,4,] TRIAZOLO [1,5, -A] PYRIDIN-6-YL) -4- (3,4-DICHLORPHENYL) -1,2,3,4- TETRAHYDROISOQUINOLINE AND USE thereof |
| CZ304602B6 (cs) | 2009-09-02 | 2014-07-30 | Zentiva, K. S. | Způsob krystalizace hydrochloridu (S)-N-methyl-3-(1-naftyloxy)-3-(2-thienyl)propylaminu (hydrochloridu duloxetinu) |
| EP2377525A1 (en) | 2010-03-26 | 2011-10-19 | Laboratorios del Dr. Esteve S.A. | Duloxetine enteric pellets |
| EP2558455B1 (en) | 2010-04-13 | 2017-08-09 | KRKA, D.D., Novo Mesto | Synthesis of duloxetine and/or pharmaceutically acceptable salts thereof |
| US9045468B2 (en) | 2010-08-17 | 2015-06-02 | Albany Molecular Research, Inc. | 2,5-methano- and 2,5-ethano-tetrahydrobenzazepine derivatives and use thereof to block reuptake of norepinephrine, dopamine, and serotonin |
| EP2508519A1 (en) * | 2011-04-07 | 2012-10-10 | Bioindustria Laboratorio Italiano Medicinali S.p.A In forma abbreviata Bioindustria L.I.M. S.p.A. | "Process for the preparation of duloxetine and its hydrochloride salt" |
| GR1007725B (el) | 2011-10-17 | 2012-10-18 | Φαρματεν Αβεε, | Μεθοδος δια την παρασκευη υδροχλωρικης ντουλοξετινης υψηλης καθαροτητας |
| PL224543B1 (pl) | 2013-08-21 | 2017-01-31 | Pabianickie Zakłady Farm Polfa Spółka Akcyjna | Dojelitowa tabletka duloksetyny |
| US9668975B2 (en) | 2014-10-14 | 2017-06-06 | PharmaDax Inc. | Method of preparing drug agglomerate |
| CN105777706B (zh) | 2014-12-25 | 2019-08-23 | 江苏恩华药业股份有限公司 | 一种3-[(苯并[d][1, 3]二氧戊环-4-基)-氧基]-3-芳基丙胺类化合物及其应用 |
| JP2016222628A (ja) * | 2015-06-03 | 2016-12-28 | 株式会社トクヤマ | デュロキセチン塩酸塩の製造方法 |
| JP6182183B2 (ja) * | 2015-07-07 | 2017-08-16 | 東和薬品株式会社 | デュロキセチン塩基及びデュロキセチン塩酸塩の製造方法 |
| CN106349211B (zh) * | 2016-08-26 | 2020-10-16 | 江苏恩华药业股份有限公司 | 2-甲基-3-芳氧基-3-杂芳基丙胺类化合物及应用 |
| EP3339304A1 (en) * | 2016-12-20 | 2018-06-27 | Laboratorios del Dr. Esteve, S.A. | Quinoline and isoquinoline derivatives for treating pain and pain related conditions |
| WO2020035040A1 (zh) | 2018-08-17 | 2020-02-20 | 上海璃道医药科技有限公司 | 3-芳氧基-3-五元杂芳基-丙胺类化合物及其用途 |
| EP3971181A4 (en) * | 2019-05-16 | 2023-11-08 | Shanghai Leado Pharmatech Co. Ltd. | 3-ARYLOXYL-3-FIVE-MEMBED HETEROARYLPROPYLAMINE COMPOUND AND CRYSTAL FORM AND USE THEREOF |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2842555A (en) * | 1954-07-27 | 1958-07-08 | Burroughs Wellcome Co | Method of preparing quaternary salts of amino carbinols |
| AT255400B (de) * | 1965-03-22 | 1967-07-10 | Chemie Linz Ag | Verfahren zur Herstellung von neuen basischen Äthern |
| US3423510A (en) * | 1966-08-31 | 1969-01-21 | Geigy Chem Corp | 3-(p-halophenyl) - 3 - (2'-pyridyl-n-methylpropylamine for the treatment of depression |
| US4018895A (en) * | 1974-01-10 | 1977-04-19 | Eli Lilly And Company | Aryloxyphenylpropylamines in treating depression |
| FR2482956A1 (fr) * | 1980-05-22 | 1981-11-27 | Synthelabo | Cyclohexylalkylamines, leurs procedes de preparation et leur application en therapeutique |
-
1986
- 1986-12-18 KR KR860014449A patent/KR880007433A/ko active Pending
-
1987
- 1987-12-17 IL IL84863A patent/IL84863A/xx not_active IP Right Cessation
- 1987-12-17 CA CA000554601A patent/CA1302421C/en not_active Expired - Lifetime
- 1987-12-17 PT PT86389A patent/PT86389B/pt unknown
- 1987-12-17 DK DK198706648A patent/DK174599B1/da not_active IP Right Cessation
- 1987-12-17 ZA ZA879472A patent/ZA879472B/xx unknown
- 1987-12-17 EG EG731/87A patent/EG18230A/xx active
- 1987-12-17 AU AU82660/87A patent/AU591007B2/en not_active Expired
- 1987-12-17 SU SU874203804A patent/SU1598865A3/ru active
- 1987-12-18 IE IE873449A patent/IE873449L/xx not_active IP Right Cessation
- 1987-12-18 DE DE200512000002 patent/DE122005000002I1/de active Pending
- 1987-12-18 PH PH36267A patent/PH26556A/en unknown
- 1987-12-18 ES ES87311181T patent/ES2019949B3/es not_active Expired - Lifetime
- 1987-12-18 EP EP87311181A patent/EP0273658B1/en not_active Expired - Lifetime
- 1987-12-18 KR KR1019870014449A patent/KR960003808B1/ko not_active Expired - Lifetime
- 1987-12-18 DE DE8787311181T patent/DE3765919D1/de not_active Expired - Lifetime
- 1987-12-18 NZ NZ222980A patent/NZ222980A/xx unknown
- 1987-12-18 AR AR87309638A patent/AR243868A1/es active
- 1987-12-18 JP JP62322617A patent/JP2549681B2/ja not_active Expired - Lifetime
- 1987-12-18 AT AT87311181T patent/ATE57924T1/de active
- 1987-12-18 HU HU875863A patent/HU206309B/hu unknown
- 1987-12-18 MX MX984587A patent/MX9845A/es unknown
- 1987-12-18 DE DE19873765919 patent/DE122005000002I2/de active Active
- 1987-12-18 CN CN87108175A patent/CN1019113B/zh not_active Expired
-
1990
- 1990-12-18 GR GR90401079T patent/GR3001207T3/el unknown
-
1992
- 1992-11-04 SG SG1149/92A patent/SG114992G/en unknown
-
1993
- 1993-07-22 HK HK696/93A patent/HK69693A/en not_active IP Right Cessation
- 1993-10-10 CY CY1682A patent/CY1682A/xx unknown
-
2005
- 2005-01-26 LU LU91131C patent/LU91131I2/fr unknown
- 2005-01-27 CY CY200500001C patent/CY2005001I1/el unknown
- 2005-01-31 NL NL300171C patent/NL300171I2/nl unknown
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