CY1118148T1 - Συνθεση που περιεχει ενωσεις τεταρτοταγους αμμωνιου - Google Patents
Συνθεση που περιεχει ενωσεις τεταρτοταγους αμμωνιουInfo
- Publication number
- CY1118148T1 CY1118148T1 CY20161100773T CY161100773T CY1118148T1 CY 1118148 T1 CY1118148 T1 CY 1118148T1 CY 20161100773 T CY20161100773 T CY 20161100773T CY 161100773 T CY161100773 T CY 161100773T CY 1118148 T1 CY1118148 T1 CY 1118148T1
- Authority
- CY
- Cyprus
- Prior art keywords
- weight
- replaced
- carbon atoms
- alkyl group
- composition containing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
- A61L12/143—Quaternary ammonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/62—Quaternary ammonium compounds
- C07C211/63—Quaternary ammonium compounds having quaternised nitrogen atoms bound to acyclic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Αυτή η εφεύρεση σχετίζεται με συνθέσεις που περιέχουν ενώσεις του τεταρτοταγούς αμμωνίου στις οποίες το άτομο αζώτου είναι αντικατεστημένο με τουλάχιστον μία ομάδα αλκυλίου (alkyl) που έχει τουλάχιστον 12 άτομα άνθρακα, που χαρακτηρίζεται από το ότι η εν λόγω σύνθεση περιλαμβάνει τουλάχιστον 20% σε βάρος ανά βάρος της ολικής σύνθεσης, αλογονίδια αμμωνίου στα οποία το άτομο αζώτου είναι αντικατεστημένο με τουλάχιστον μία ομάδα αλκυλίου (alkyl) που έχει τουλάχιστον 14 άτομα άνθρακα και περισσότερα από 5 %, κατά προτίμηση περισσότερο από 7 % σε βάρος ανά βάρος της ολικής σύνθεσης, αλογονίδια αμμωνίου στα οποία το άτομο αζώτου είναι αντικατεστημένο με τουλάχιστον μία ομάδα αλκυλίου (alkyl) που έχει τουλάχιστον 16 άτομα άνθρακα. Αυτή η εφεύρεση σχετίζεται επίσης με οφθαλμικά γαλακτώματα λαδιού μέσα σε νερό που περιέχουν τέτοιες συνθέσεις που είναι χρήσιμες για την φροντίδα των ματιών ή για την θεραπεία παθήσεων των ματιών.
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06291236.5A EP1891939B1 (en) | 2006-07-28 | 2006-07-28 | Compositions containing quaternary ammonium compounds |
| US11/494,493 US20080026013A1 (en) | 2006-07-28 | 2006-07-28 | Compositions containing quaternary ammonium compounds |
| EP07112097 | 2007-07-09 | ||
| PCT/IB2007/053441 WO2008035246A2 (en) | 2006-07-28 | 2007-07-10 | Compositions containing quaternary ammonium compounds |
| EP07787998.9A EP2049079B1 (en) | 2006-07-28 | 2007-07-27 | Compositions containing quaternary ammonium compounds |
| EP11165011.5A EP2404593B1 (en) | 2006-07-28 | 2007-07-27 | Composition containing quaternary ammonium compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1118148T1 true CY1118148T1 (el) | 2017-06-28 |
Family
ID=65014357
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20161100773T CY1118148T1 (el) | 2006-07-28 | 2016-08-05 | Συνθεση που περιεχει ενωσεις τεταρτοταγους αμμωνιου |
| CY20161101244T CY1118436T1 (el) | 2006-07-28 | 2016-12-02 | Συνθεσεις που περιεχουν ενωσεις τεταρτοταγους αμμωνιου |
| CY2017007C CY2017007I1 (el) | 2006-07-28 | 2017-02-22 | Συνθεσεις που περιεχουν ενωσεις τεταρτοταγους αμμωνιου |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20161101244T CY1118436T1 (el) | 2006-07-28 | 2016-12-02 | Συνθεσεις που περιεχουν ενωσεις τεταρτοταγους αμμωνιου |
| CY2017007C CY2017007I1 (el) | 2006-07-28 | 2017-02-22 | Συνθεσεις που περιεχουν ενωσεις τεταρτοταγους αμμωνιου |
Country Status (17)
| Country | Link |
|---|---|
| US (7) | US7973081B2 (el) |
| EP (2) | EP2404593B1 (el) |
| JP (1) | JP5441058B2 (el) |
| KR (2) | KR101507097B1 (el) |
| AU (1) | AU2007278141B2 (el) |
| CA (1) | CA2659322C (el) |
| CY (3) | CY1118148T1 (el) |
| DK (2) | DK2404593T3 (el) |
| ES (2) | ES2606467T3 (el) |
| HU (2) | HUE030841T2 (el) |
| IL (2) | IL196740A (el) |
| LT (2) | LT2049079T (el) |
| LU (1) | LUC00006I2 (el) |
| PL (2) | PL2404593T3 (el) |
| PT (2) | PT2049079T (el) |
| SI (2) | SI2404593T1 (el) |
| WO (2) | WO2008035246A2 (el) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2916636B1 (fr) * | 2007-05-29 | 2009-09-04 | Octalia Technologies | Vehicule sous forme d'une emulsion huile-dans-eau notamment destine a une utilisation ophtalmique ou dermocosmetique |
| CA2725523C (en) * | 2008-05-28 | 2017-01-10 | Alcon Research, Ltd. | Self-preserved emulsions |
| EP2228058A1 (en) | 2009-03-04 | 2010-09-15 | Novagali Pharma S.A. | Anionic oil-in-water emulsion containing prostaglandins and uses thereof |
| EP2228057A1 (en) * | 2009-03-04 | 2010-09-15 | Novagali Pharma S.A. | Cationic oil-in-water emulsions containing prostaglandins and uses thereof |
| BRPI1009982A2 (pt) | 2009-05-01 | 2017-06-27 | Signal Investment & Man Co | composição antimicrobiana hidratante |
| CA2764802A1 (en) | 2009-06-05 | 2010-12-09 | Allergan, Inc. | Artificial tears and therapeutic uses |
| EP2389939A1 (en) | 2010-05-28 | 2011-11-30 | Novagali Pharma S.A. | Use of prostaglandins F2alpha and analogues for the healing of corneal and conjunctival lesions |
| WO2013098841A1 (en) * | 2011-10-31 | 2013-07-04 | Fdc Limited | Nanodispersion of poorly water soluble drug(s) |
| PL2787969T3 (pl) * | 2011-12-07 | 2021-12-20 | Allergan, Inc. | Skuteczne dostarczanie lipidów do ludzkiego filmu łzowego z zastosowaniem układu emulsji wrażliwej na sól |
| US9907826B2 (en) | 2011-12-07 | 2018-03-06 | Allergan, Inc. | Efficient lipid delivery to human tear film using a salt-sensitive emulsion system |
| EP2664329A1 (de) * | 2012-05-15 | 2013-11-20 | F. Holzer GmbH | Ophthalmologisches Vehikelsystem |
| CA2947274C (en) * | 2014-04-28 | 2019-03-19 | Hampton Technologies | Ophthalmic compositions and methods for treating eyes |
| US20160074178A1 (en) * | 2014-09-17 | 2016-03-17 | Van Phillips | METHODS FOR PREPARING PRECISELY FITTED CASTS for PROSTHETICS |
| EP3011959A1 (en) * | 2014-10-23 | 2016-04-27 | Santen SAS | Quaternary ammonium compound for use as an inhibitor of protein kinase C alpha |
| US10279005B2 (en) | 2014-11-25 | 2019-05-07 | Allergan, Inc. | Stabilized omega-3 ophthalmic compositions |
| US11324800B2 (en) | 2015-01-15 | 2022-05-10 | Wellspring Ophthalmics, Inc. | Aqueous suspensions of cyclosporin |
| US20200237859A1 (en) | 2019-01-25 | 2020-07-30 | Newport Research, Inc. | Aqueous suspensions of cyclosporin |
| PL3266446T3 (pl) * | 2016-07-07 | 2019-05-31 | Salvat Lab Sa | Kompozycja oftalmiczna zawierająca olej rycynowy i trójgliceryd o średniej długości łańcucha |
| HRP20250306T1 (hr) * | 2020-09-18 | 2025-04-25 | Omnivision Gmbh | Oftalmološki pripravak na bazi lipida za liječenje suhog oka |
| US20230398175A1 (en) | 2020-11-09 | 2023-12-14 | Scai Therapeutics | Solid cyclosporin a and dispersion composition comprising same |
| US11471475B1 (en) | 2022-03-08 | 2022-10-18 | Ralph P. Stone | Ophthalmic suspension vehicles and related methods for pharmaceutical ingredient delivery |
| US20240009124A1 (en) * | 2022-07-05 | 2024-01-11 | Primera Compounding, LLC | Ophthalmic Suspension Base having a Micro-fluidized Positively Charged Nanoparticle |
| WO2024069490A1 (en) * | 2022-09-28 | 2024-04-04 | Polaroid Ip B.V. | Antimicrobial coating compositions |
| WO2024226686A2 (en) * | 2023-04-24 | 2024-10-31 | Emory University | Aminoadipate-semialdehyde synthase inhibitors and methods of treating cancer |
| TR2023007877A2 (tr) * | 2023-07-06 | 2023-10-23 | Ardi̇ Farma İlaç Pazarlama Ti̇caret Li̇mi̇ted Şi̇rketi̇ | Stabi̇l çoklu doz si̇klospori̇n yağ i̇çi̇nde su emülsi̇yon kompozi̇syonlari |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB633175A (en) * | 1946-09-03 | 1949-12-12 | Parke Davis & Co | Antibiotic preparations and process for obtaining the same |
| USB724600I5 (el) * | 1968-04-26 | |||
| AU499860B2 (en) | 1975-04-24 | 1979-05-03 | Honda Giken Kogyo Kabushiki Kaisha | Deflector plate to equalise fuel distribution in induction gas flow |
| US5188826A (en) | 1988-02-08 | 1993-02-23 | Insite Vision Incorporated | Topical ophthalmic suspensions |
| FR2648462B1 (fr) * | 1989-06-15 | 1994-01-28 | Oreal | Procede pour ameliorer l'efficacite therapeutique de corticosteroides liposolubles et composition pour la mise en oeuvre de ce procede |
| JPH05116286A (ja) | 1991-10-25 | 1993-05-14 | Matsushita Electric Ind Co Ltd | インク吐出装置 |
| IL101241A (en) | 1992-03-16 | 1997-11-20 | Yissum Res Dev Co | Pharmaceutical or cosmetic composition comprising stabilized oil-in-water type emulsion as carrier |
| IL103907A0 (en) * | 1992-11-27 | 1993-04-04 | Pharmos Corp | Ophthalmic compositions |
| CA2142103C (en) | 1992-08-28 | 2003-07-08 | Haim Aviv | Submicron emulsions as ocular drug delivery vehicles |
| US5951988A (en) * | 1993-03-30 | 1999-09-14 | University Of Saskatchewan | Adjuvant formulation with enhanced immunogenic activity, and related compositions and methods |
| FI108514B (fi) | 1993-06-25 | 2002-02-15 | Cusi Lab | Polymeerimembraanien käyttö sellaisten farmaseuttisten liuosten jakelussa, jotka sisältävät kvaternäärisiä ammoniumyhdisteitä |
| ATE227114T1 (de) * | 1993-08-30 | 2002-11-15 | Unilever Nv | Haarwasch- und konditionierungsmittel |
| DE69527624T2 (de) | 1994-05-20 | 2003-04-03 | Novavax, Inc. | Antimikrobielle öl-in-wasser-emulsionen |
| US5547990A (en) * | 1994-05-20 | 1996-08-20 | Lonza, Inc. | Disinfectants and sanitizers with reduced eye irritation potential |
| US5435998A (en) * | 1994-08-03 | 1995-07-25 | Abelson; Mark B. | Treatment of low-tension glaucoma by topical administration of calcium channel blocking agents |
| ES2094688B1 (es) | 1994-08-08 | 1997-08-01 | Cusi Lab | Manoemulsion del tipo de aceite en agua, util como vehiculo oftalmico y procedimiento para su preparacion. |
| US5767153A (en) | 1995-06-07 | 1998-06-16 | Insite Vision Incorporated | Sustained release emulsions |
| TW446563B (en) * | 1996-01-16 | 2001-07-21 | Colgate Palmolive Co | Low static conditioning shampoo |
| US6071904A (en) | 1996-12-11 | 2000-06-06 | Alcon Laboratories, Inc. | Process for manufacturing ophthalmic suspensions |
| DE69807281T2 (de) | 1997-05-14 | 2003-04-17 | Mitsubishi Chemical Corp., Tokio/Tokyo | Difluprednat enthaltende Zusammensetzungen |
| US20020169138A1 (en) * | 1997-10-24 | 2002-11-14 | Southern Research Institute | Delivery vehicles for bioactive agents and uses thereof |
| AU3548499A (en) | 1998-04-02 | 1999-10-25 | Schepens Eye Research Institute, Inc., The | Corneal organ culture system for chemical toxicity tests of consumer products |
| FR2780879B1 (fr) * | 1998-07-09 | 2002-09-20 | Oreal | Composition cosmetique photoprotectrice contenant un tensio-actif anionique, un compose filtrant le rayonnement ultraviolet et un compose cationique ou zwitterionique amphiphile et son utilisation |
| EP1115406A4 (en) * | 1998-09-25 | 2003-03-05 | Alcon Lab Inc | PLEASANT OPHTHALMIC COMPOSITION, DELAYED DELIVERY OF ACTIVE SUBSTANCES AND METHODS FOR EYE TREATMENT |
| US6030789A (en) | 1999-03-10 | 2000-02-29 | The Gillette Company | Human conjunctival epithelial cell lines with an extended life span |
| US6635676B2 (en) | 1999-04-28 | 2003-10-21 | Regents Of The University Of Michigan | Non-toxic antimicrobial compositions and methods of use |
| DK1214056T3 (da) | 1999-09-24 | 2004-02-09 | Alcon Inc | Topiske suspensionsformuleringer indeholdende ciprofloxacin og dexamethason |
| EP1142566B1 (fr) | 2000-04-07 | 2003-10-01 | Laboratoire Medidom S.A. | Formulations ophtalmiques à base de ciclosporine, d'acide hyaluronique et du polysorbate |
| US20030017181A1 (en) * | 2001-05-31 | 2003-01-23 | Rood Gloria A. | Dermatological compositions and methods |
| US7314624B2 (en) | 2001-06-05 | 2008-01-01 | The Regents Of The University Of Michigan | Nanoemulsion vaccines |
| US6872705B2 (en) | 2001-07-13 | 2005-03-29 | Allergan, Inc. | Use of antimicrobial peptides as preservatives in ophthalmic preparations, including solutions, emulsions, and suspensions |
| US6656460B2 (en) * | 2001-11-01 | 2003-12-02 | Yissum Research Development | Method and composition for dry eye treatment |
| CN100335036C (zh) | 2001-11-01 | 2007-09-05 | 耶路撒冷希伯来语大学依苏姆研究开发公司 | 用于干眼症治疗的方法和组合物 |
| US20030165545A1 (en) * | 2002-01-30 | 2003-09-04 | Allergan, Inc. | Ophthalmic compositions including oil-in-water emulsions, and methods for making and using same |
| AU2003230691A1 (en) | 2002-03-20 | 2003-10-08 | Elan Pharma International Ltd. | Nanoparticulate compositions of angiogenesis inhibitors |
| US20050059583A1 (en) | 2003-09-15 | 2005-03-17 | Allergan, Inc. | Methods of providing therapeutic effects using cyclosporin components |
| JP5382972B2 (ja) | 2003-12-26 | 2014-01-08 | ロート製薬株式会社 | 粘度低下が防止された組成物 |
| US20050175651A1 (en) | 2004-01-09 | 2005-08-11 | L'oreal | Aqueous dispersion of nanocapsules with an oily core |
| US20050158349A1 (en) | 2004-01-20 | 2005-07-21 | Jampani Hanuman B. | Two-phase compositions containing alcohol |
| EP1611879B1 (en) | 2004-07-02 | 2009-08-12 | Novagali Pharma SA | Use of emulsions for intra- and periocular injection |
| EP1655021B1 (en) * | 2004-11-09 | 2008-10-29 | Novagali Pharma SA | Oil-in-water type emulsion with low concentration of cationic agent and positive zeta potential |
| CA2586074C (en) | 2004-11-09 | 2013-07-23 | Novagali Pharma Sa | Ophthalmic oil-in-water type emulsion with stable positive zeta potential |
| AU2007208169A1 (en) | 2006-01-30 | 2007-08-02 | Lawrence R. Bernstein | Use of gallium to treat biofilm-associated infectons |
| US20080026013A1 (en) * | 2006-07-28 | 2008-01-31 | Laura Rabinovich-Guilatt | Compositions containing quaternary ammonium compounds |
| US20090018057A1 (en) * | 2007-07-09 | 2009-01-15 | Gregory Lambert | OIL IN WATER EMULSION COMPRISING NSAIDs AND QUATERNARY AMMONIUM HALIDES |
-
2007
- 2007-07-10 WO PCT/IB2007/053441 patent/WO2008035246A2/en not_active Ceased
- 2007-07-27 JP JP2009521280A patent/JP5441058B2/ja not_active Expired - Fee Related
- 2007-07-27 EP EP11165011.5A patent/EP2404593B1/en active Active
- 2007-07-27 PT PT77879989T patent/PT2049079T/pt unknown
- 2007-07-27 HU HUE07787998A patent/HUE030841T2/en unknown
- 2007-07-27 LT LTEP07787998.9T patent/LT2049079T/lt unknown
- 2007-07-27 SI SI200731814A patent/SI2404593T1/sl unknown
- 2007-07-27 PL PL11165011.5T patent/PL2404593T3/pl unknown
- 2007-07-27 WO PCT/EP2007/057784 patent/WO2008012367A2/en not_active Ceased
- 2007-07-27 PT PT111650115T patent/PT2404593T/pt unknown
- 2007-07-27 PL PL07787998T patent/PL2049079T3/pl unknown
- 2007-07-27 ES ES07787998.9T patent/ES2606467T3/es active Active
- 2007-07-27 SI SI200731866A patent/SI2049079T1/sl unknown
- 2007-07-27 KR KR1020147003945A patent/KR101507097B1/ko active Active
- 2007-07-27 HU HUE11165011A patent/HUE029987T2/en unknown
- 2007-07-27 CA CA2659322A patent/CA2659322C/en active Active
- 2007-07-27 DK DK11165011.5T patent/DK2404593T3/en active
- 2007-07-27 ES ES11165011.5T patent/ES2586381T3/es active Active
- 2007-07-27 KR KR1020097004115A patent/KR101507465B1/ko active Active
- 2007-07-27 US US11/829,428 patent/US7973081B2/en active Active
- 2007-07-27 AU AU2007278141A patent/AU2007278141B2/en active Active
- 2007-07-27 EP EP07787998.9A patent/EP2049079B1/en active Active
- 2007-07-27 DK DK07787998.9T patent/DK2049079T3/da active
-
2009
- 2009-01-27 IL IL196740A patent/IL196740A/en active IP Right Grant
-
2011
- 2011-04-28 US US13/096,512 patent/US8524779B2/en active Active
-
2013
- 2013-08-02 US US13/957,621 patent/US9220694B2/en active Active
-
2015
- 2015-09-21 IL IL241753A patent/IL241753B/en active IP Right Grant
- 2015-11-17 US US14/943,649 patent/US9956289B2/en active Active
-
2016
- 2016-08-05 CY CY20161100773T patent/CY1118148T1/el unknown
- 2016-12-02 CY CY20161101244T patent/CY1118436T1/el unknown
-
2017
- 2017-02-15 LT LTPA2017003C patent/LTC2049079I2/lt unknown
- 2017-02-22 CY CY2017007C patent/CY2017007I1/el unknown
- 2017-02-23 LU LU00006C patent/LUC00006I2/en unknown
-
2018
- 2018-04-05 US US15/946,325 patent/US10842873B2/en active Active
-
2020
- 2020-10-21 US US16/949,237 patent/US11612658B2/en active Active
-
2023
- 2023-02-10 US US18/167,125 patent/US20230181738A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1118148T1 (el) | Συνθεση που περιεχει ενωσεις τεταρτοταγους αμμωνιου | |
| CY1118096T1 (el) | Ρυθμιστες υποδοχεα οπιοειδους | |
| CY1107871T1 (el) | Παραγωγα πυριμιδινης και η χρηση τους ως ρυθμιστων cb2 | |
| EA202193338A1 (ru) | Терапевтические композиции, включающие дейтерированные или частично дейтерированные соединения n,n-диметилтриптамина | |
| CY1106674T1 (el) | Αζαδικυκλικοι ετεροκυκλοι σαν ρυθμιστες υποδοχεα κανναβινοειδους | |
| CY1114457T1 (el) | Συνθεσεις που περιεχουν ενωσεις τεταρτοταγους αμμωνιου (quaternary ammonium) | |
| CY1121162T1 (el) | M-csf-ειδικο μονοκλωνικο αντισωμα και χρησεις αυτου | |
| CY1121898T1 (el) | Ενωσεις αμιδιου ως αγωνιστες tου υποδοχεα 5-ht4 | |
| EA200600048A1 (ru) | Производные бензазепина, используемые для лечения заболеваний, ассоциированных с 5-ht-рецептором | |
| CY1118846T1 (el) | Τριαζολοπυριδαζινες ως ρυθμιστες της κινασης τυροσινης | |
| CY1121865T1 (el) | Οφθαλμολογικες συνθεσεις και η χρηση τους | |
| CY1118299T1 (el) | Ανοσοκατασταλτικες ενωσεις και συνθεσεις | |
| BRPI0414313A (pt) | inibidores de citocinas | |
| CY1109860T1 (el) | Παραγοντες υποδοχεα ισταμινης η3, παρασκευη και θεραπευτικες χρησεις | |
| CY1115489T1 (el) | ΠΑΡΑΛΛΑΓΜΑΤΑ ΠΡΟΕΡΧΟΜΕΝΑ ΑΠΟ ActRIIB ΚΑΙ ΧΡΗΣΕΙΣ ΑΥΤΩΝ | |
| CY1110419T1 (el) | Τρικυκλικες ενωσεις με βαση το 1,6-διυδρο-1,3,5,6-tetpaaza-as-ινδακενιο και φαρμακευτικες συνθεσεις που τις περιεχουν ως αναστολεις της ενζυμικης ενεργοτητας της ικκ | |
| PT729468E (pt) | Antagonistas nao peptidicos de receptores de taquiquininas | |
| CY1110343T1 (el) | 2-(πυριδιν-2-υλο)-πυριμιδινες και η χρησιμοποιηση του για την καταπολεμηση επιζημιων μυκητων | |
| ATE430744T1 (de) | Thiazolylpiperidin-derivate nützlich als h3 rezeptor modulatoren | |
| CY1113257T1 (el) | Παραγωγα βενζυλοπιπεραζινης τα οποια ειναι χρησιμα στη θεραπεια γαστρεντερικων διαταραχων | |
| PA8568101A1 (es) | Indolil-urea derivados de tienopiridinas utiles como agentes antiangiogenicos, y procedimientos para su uso | |
| CY1109214T1 (el) | Μειγματα μυκητοκτονου που βασιζονται σε παραγωγα καρβαμικου και εντομοκτονα | |
| AR053196A1 (es) | N- (pirimidin -2-il-metil) carboxamidas y su empleo como herbicidas y reguladores del crecimiento de las plantas y un procedimiento para combatir plantas no deseadas que las utiliza. | |
| CY1114735T1 (el) | Θεραπευτικες συνθεσεις οι οποιες περιεχουν εναν ειδικο ανταγωνιστη του υποδοχεα της ενδοθηλινης και εναν αναστολεα της pde5 | |
| SA522431498B1 (ar) | مشتقات 3، 6-داي أمينو-بيريدازين-3-يل، تركيبات صيدلية تحتوي عليها واستخدامها في صورة عوامل مساعدة على تلاشي الخلايا |