Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ct Nac De Sanidad AgropecuariafiledCriticalCt Nac De Sanidad Agropecuaria
Priority to CU1998181ApriorityCriticalpatent/CU22823A1/en
Publication of CU22823A1publicationCriticalpatent/CU22823A1/en
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents
(AREA)
Micro-Organisms Or Cultivation Processes Thereof
(AREA)
Abstract
Se desarrolla un procedimiento que permite obtener una cepa de viruela aviar adaptada a cultivos de fibroblastos de embrión de pollo, modificada con características biológicas y moleculares que la diferencian de otras cepas vacunales. Se desarrolla a su vez un nuevo método para la extracción del virus intracelular que permite su producción, evaluación y aplicación como cepa vacunal con inocuidad y eficacia para la protección contra la enfermedad.A procedure is developed that allows to obtain an avian smallpox strain adapted to chicken embryo fibroblast cultures, modified with biological and molecular characteristics that differentiate it from other vaccine strains. A new method for the extraction of the intracellular virus that allows its production, evaluation and application as a vaccine strain with safety and efficacy for the protection against the disease is developed.
CU1998181A1998-12-011998-12-01
PROCEDURE FOR OBTAINING A LIVING VACCINE FROM VIRUELA AVIAR
CU22823A1
(en)
LIVING RECOMBINANT IMMUNOGENIC COMPOSITION COMPRISING THE NEWCASTLE DISEASE VIRUS (NDV) EXPRESSING THE S1 SUBUNIT AND RBD OF THE SARS-CoV-2 SPIKE PROTEIN
immunogenic composition, vaccine, use of a composition or vaccine, method for producing an immunogenic composition, and, use of vlps or capsomeres of hpv 16 and 18 with vlps or capsomeres of at least one other hpv of the cancer-causing type