CU20140126A7 - MANUFACTURING PROCEDURE FOR A PHARMACEUTICAL DOSAGE FORM INCLUDING NIFEDIPINE AND CANDESARTÁN CILEXETILO - Google Patents
MANUFACTURING PROCEDURE FOR A PHARMACEUTICAL DOSAGE FORM INCLUDING NIFEDIPINE AND CANDESARTÁN CILEXETILOInfo
- Publication number
- CU20140126A7 CU20140126A7 CU2014000126A CU20140126A CU20140126A7 CU 20140126 A7 CU20140126 A7 CU 20140126A7 CU 2014000126 A CU2014000126 A CU 2014000126A CU 20140126 A CU20140126 A CU 20140126A CU 20140126 A7 CU20140126 A7 CU 20140126A7
- Authority
- CU
- Cuba
- Prior art keywords
- pharmaceutical dosage
- dosage form
- cilexetilo
- candesartán
- manufacturing procedure
- Prior art date
Links
- 239000002552 dosage form Substances 0.000 title abstract 3
- HYIMSNHJOBLJNT-UHFFFAOYSA-N nifedipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1[N+]([O-])=O HYIMSNHJOBLJNT-UHFFFAOYSA-N 0.000 title abstract 3
- 229960001597 nifedipine Drugs 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- GHOSNRCGJFBJIB-UHFFFAOYSA-N Candesartan cilexetil Chemical compound C=12N(CC=3C=CC(=CC=3)C=3C(=CC=CC=3)C3=NNN=N3)C(OCC)=NC2=CC=CC=1C(=O)OC(C)OC(=O)OC1CCCCC1 GHOSNRCGJFBJIB-UHFFFAOYSA-N 0.000 abstract 2
- 229960004349 candesartan cilexetil Drugs 0.000 abstract 2
- 239000002934 diuretic Substances 0.000 abstract 2
- 230000001882 diuretic effect Effects 0.000 abstract 2
- 239000012729 immediate-release (IR) formulation Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a procedimientos de fabricación para la preparación de una forma de dosificación farmacéutica que comprende nifedipina y candesartán cilexetilo y, opcionalmente, al menos un diurético, caracterizada por que la nifedipina se libera en el organismo de una manera controlada (modificada) y el candesartán cilexetilo se libera rápidamente (liberación inmediata [LI]) y, opcionalmente, el diurético se libera rápidamente (liberación inmediata [LI]), y a las formas de dosificación farmacéuticas que se pueden obtener mediante dichos procedimientos.The present invention relates to manufacturing processes for the preparation of a pharmaceutical dosage form comprising nifedipine and candesartan cilexetil and, optionally, at least one diuretic, characterized in that nifedipine is released in the body in a controlled (modified) manner. and candesartan cilexetil is rapidly released (immediate release [LI]) and, optionally, the diuretic is rapidly released (immediate release [LI]), and to the pharmaceutical dosage forms that can be obtained by such procedures.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13151946 | 2013-01-18 | ||
| PCT/EP2013/059110 WO2013167453A1 (en) | 2012-05-07 | 2013-05-02 | Process for manufacturing a pharmaceutical dosage form comprising nifedipine and candesartan cilexetil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CU20140126A7 true CU20140126A7 (en) | 2015-03-30 |
Family
ID=47603379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU2014000126A CU20140126A7 (en) | 2013-01-18 | 2014-11-03 | MANUFACTURING PROCEDURE FOR A PHARMACEUTICAL DOSAGE FORM INCLUDING NIFEDIPINE AND CANDESARTÁN CILEXETILO |
Country Status (1)
| Country | Link |
|---|---|
| CU (1) | CU20140126A7 (en) |
-
2014
- 2014-11-03 CU CU2014000126A patent/CU20140126A7/en unknown
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