CU20130165A7 - MODIFIED RELEASE OF 4-METHYL-3 - [[- 4- (3- PIRIDINIL) -2-PYRIMIDINYL] AMINO] -N-5- (4- METHYL-1H-IMIDAZOL-1- IL) -3- (TRIFLUOROMETIL) FENIL] SOLUBILIZED BENZAMIDE USING ORGANIC ACIDS - Google Patents
MODIFIED RELEASE OF 4-METHYL-3 - [[- 4- (3- PIRIDINIL) -2-PYRIMIDINYL] AMINO] -N-5- (4- METHYL-1H-IMIDAZOL-1- IL) -3- (TRIFLUOROMETIL) FENIL] SOLUBILIZED BENZAMIDE USING ORGANIC ACIDSInfo
- Publication number
- CU20130165A7 CU20130165A7 CU2013000165A CU20130165A CU20130165A7 CU 20130165 A7 CU20130165 A7 CU 20130165A7 CU 2013000165 A CU2013000165 A CU 2013000165A CU 20130165 A CU20130165 A CU 20130165A CU 20130165 A7 CU20130165 A7 CU 20130165A7
- Authority
- CU
- Cuba
- Prior art keywords
- methyl
- organic acids
- piridinil
- trifluorometil
- fenil
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Se inventaron composiciones farmacéuticas solubles de nilotinib, o de una sal farmacéuticamente aceptable del mismo, utilizando uno o más ácidos orgánicos que funcionan como un agente solubilizante, que aumentan la biodisponibilidad del nilotinib, y que suprimen el efecto del alimento asociado con ciertas composiciones de nilotinib. Las composiciones farmacéuticas están en la forma de formas de dosificación oral sólidas, incluyendo cápsulas y tabletas.Soluble pharmaceutical compositions of nilotinib, or a pharmaceutically acceptable salt thereof, were invented, using one or more organic acids that function as a solubilizing agent, which increase the bioavailability of nilotinib, and which suppress the effect of the food associated with certain nilotinib compositions. . The pharmaceutical compositions are in the form of solid oral dosage forms, including capsules and tablets.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161541306P | 2011-09-30 | 2011-09-30 | |
| PCT/US2012/042205 WO2012174082A1 (en) | 2011-06-14 | 2012-06-13 | Modified release of 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-n-5-(4-methyl-1h-imidazol-1-yl)-3-(trifluoromethyl)phenyl] benzamide solubilized using organic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CU20130165A7 true CU20130165A7 (en) | 2014-04-24 |
Family
ID=52394773
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU2013000165A CU20130165A7 (en) | 2011-09-30 | 2013-12-16 | MODIFIED RELEASE OF 4-METHYL-3 - [[- 4- (3- PIRIDINIL) -2-PYRIMIDINYL] AMINO] -N-5- (4- METHYL-1H-IMIDAZOL-1- IL) -3- (TRIFLUOROMETIL) FENIL] SOLUBILIZED BENZAMIDE USING ORGANIC ACIDS |
Country Status (2)
| Country | Link |
|---|---|
| CU (1) | CU20130165A7 (en) |
| TN (1) | TN2013000440A1 (en) |
-
2013
- 2013-10-29 TN TNP2013000440A patent/TN2013000440A1/en unknown
- 2013-12-16 CU CU2013000165A patent/CU20130165A7/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TN2013000440A1 (en) | 2015-03-30 |
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