CU20100004A7 - PYRIMIDINE MORFOLINE DERIVATIVES USED IN DISEASES RELATED TO MTOR QUINASA AND / OR PI3K - Google Patents
PYRIMIDINE MORFOLINE DERIVATIVES USED IN DISEASES RELATED TO MTOR QUINASA AND / OR PI3KInfo
- Publication number
- CU20100004A7 CU20100004A7 CU20100004A CU20100004A CU20100004A7 CU 20100004 A7 CU20100004 A7 CU 20100004A7 CU 20100004 A CU20100004 A CU 20100004A CU 20100004 A CU20100004 A CU 20100004A CU 20100004 A7 CU20100004 A7 CU 20100004A7
- Authority
- CU
- Cuba
- Prior art keywords
- mtor
- pi3k
- morfoline
- quinasa
- pyrimidine
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 108091007960 PI3Ks Proteins 0.000 title abstract 2
- 102000010400 1-phosphatidylinositol-3-kinase activity proteins Human genes 0.000 title 1
- 101150097381 Mtor gene Proteins 0.000 title 1
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 title 1
- 102100023085 Serine/threonine-protein kinase mTOR Human genes 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 102000038030 PI3Ks Human genes 0.000 abstract 1
- 102000013530 TOR Serine-Threonine Kinases Human genes 0.000 abstract 1
- 108010065917 TOR Serine-Threonine Kinases Proteins 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un compuesto de fórmula (I) ESPACIO PARA LA FÓRMULA o una sal farmacéuticamente aceptable del mismo, procesos para su preparación, composiciones farmacéuticas que los contienen y su uso en terapia, por ejemplo en el tratamiento de enfermedad proliferativa tal como cáncer y particularmente en una enfermedad mediada por una quinasa mTOR quinasa y/o una o más enzimas PI3K.A compound of formula (I) SPACE FOR FORMULA or a pharmaceutically acceptable salt thereof, processes for its preparation, pharmaceutical compositions containing them and their use in therapy, for example in the treatment of proliferative disease such as cancer and particularly in a mTOR kinase kinase-mediated disease and / or one or more PI3K enzymes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20100004A CU20100004A7 (en) | 2010-01-08 | 2010-01-08 | PYRIMIDINE MORFOLINE DERIVATIVES USED IN DISEASES RELATED TO MTOR QUINASA AND / OR PI3K |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20100004A CU20100004A7 (en) | 2010-01-08 | 2010-01-08 | PYRIMIDINE MORFOLINE DERIVATIVES USED IN DISEASES RELATED TO MTOR QUINASA AND / OR PI3K |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CU20100004A7 true CU20100004A7 (en) | 2011-05-27 |
Family
ID=44306259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU20100004A CU20100004A7 (en) | 2010-01-08 | 2010-01-08 | PYRIMIDINE MORFOLINE DERIVATIVES USED IN DISEASES RELATED TO MTOR QUINASA AND / OR PI3K |
Country Status (1)
| Country | Link |
|---|---|
| CU (1) | CU20100004A7 (en) |
-
2010
- 2010-01-08 CU CU20100004A patent/CU20100004A7/en unknown
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