CR8145A - Regulacion de expresion de gen metalproteinasa de la matriz usando senales electricas y electromagneticas especificas y selectivas - Google Patents
Regulacion de expresion de gen metalproteinasa de la matriz usando senales electricas y electromagneticas especificas y selectivasInfo
- Publication number
- CR8145A CR8145A CR8145A CR8145A CR8145A CR 8145 A CR8145 A CR 8145A CR 8145 A CR8145 A CR 8145A CR 8145 A CR8145 A CR 8145A CR 8145 A CR8145 A CR 8145A
- Authority
- CR
- Costa Rica
- Prior art keywords
- expression
- specific
- gene
- electromagnetic signals
- matrix
- Prior art date
Links
- 239000011159 matrix material Substances 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 108010000684 Matrix Metalloproteinases Proteins 0.000 abstract 1
- 210000001188 articular cartilage Anatomy 0.000 abstract 1
- 210000003321 cartilage cell Anatomy 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0004—Homeopathy; Vitalisation; Resonance; Dynamisation, e.g. esoteric applications; Oxygenation of blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H39/00—Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/326—Applying electric currents by contact electrodes alternating or intermittent currents for promoting growth of cells, e.g. bone cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Rheumatology (AREA)
- General Engineering & Computer Science (AREA)
- Radiology & Medical Imaging (AREA)
- Hematology (AREA)
- Rehabilitation Therapy (AREA)
- Cell Biology (AREA)
- Pain & Pain Management (AREA)
- Alternative & Traditional Medicine (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
Abstract
Metodos y dispositivos para la regulacion de la expresion del gen de metaloproteinasa de la matriz en celulas del cartilago a traves de la aplicacion de campos generados por senales electricas y electromagneticas especificas y selectivas en el tratamiento del cartilago articular enfermo o lesionado.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/461,188 US7429471B2 (en) | 2000-02-23 | 2003-06-13 | Regulation of matrix metalloproteinase gene expression using specific and selective electrical and electromagnetic signals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR8145A true CR8145A (es) | 2006-07-14 |
Family
ID=33538972
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR8145A CR8145A (es) | 2003-06-13 | 2005-12-13 | Regulacion de expresion de gen metalproteinasa de la matriz usando senales electricas y electromagneticas especificas y selectivas |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7429471B2 (es) |
| EP (1) | EP1643953A4 (es) |
| JP (1) | JP2007502693A (es) |
| KR (1) | KR100856964B1 (es) |
| CN (1) | CN1822807A (es) |
| AU (1) | AU2004249202A1 (es) |
| BR (1) | BRPI0411369A (es) |
| CA (1) | CA2529374C (es) |
| CR (1) | CR8145A (es) |
| EG (1) | EG24170A (es) |
| IL (1) | IL172508A0 (es) |
| MX (1) | MXPA05013493A (es) |
| NO (1) | NO20060193L (es) |
| WO (1) | WO2004112708A2 (es) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7429471B2 (en) | 2000-02-23 | 2008-09-30 | The Trustees Of The University Of Pennsylvania | Regulation of matrix metalloproteinase gene expression using specific and selective electrical and electromagnetic signals |
| US7374916B2 (en) | 2000-02-23 | 2008-05-20 | The Trustees Of The University Of Pennsylvania | Regulation of aggrecan gene expression using specific and selective electrical and electromagnetic signals |
| US7022506B2 (en) * | 2000-02-23 | 2006-04-04 | The Trustees Of The University Of Pennsylvania | Method and device for treating osteoarthritis, cartilage disease, defects and injuries in the human knee |
| US8313908B2 (en) | 2000-02-23 | 2012-11-20 | The Trustees Of The University Of Pennsylvania | Regulation of stem cell gene production with specific and selective electric and electromagnetic fields |
| US7465566B2 (en) | 2000-02-23 | 2008-12-16 | The Trustees Of The University Of Pennsylvania | Regulation of genes via application of specific and selective electrical and electromagnetic signals |
| US7981611B2 (en) * | 2000-02-23 | 2011-07-19 | The Trustees Of The University Of Pennsylvania | Regulation of fibroblastic growth factor-2 (FGF-2) gene expression in living cells with the application of specific and selective electric and electromagnetic fields |
| US7465546B2 (en) * | 2000-02-23 | 2008-12-16 | The Trustees Of The University Of Pennsylvania | Regulation of transforming growth factor-beta (TGF-β) gene expression in living cells via the application of specific and selective electric and electromagnetic fields |
| AU2004291111A1 (en) * | 2003-11-14 | 2005-06-02 | The Trustees Of The University Of Pennsylvania | Method and device for treating osteoarthritis and cartilage disease, defects, and injuries in the human hip |
| US9440089B2 (en) | 2003-12-05 | 2016-09-13 | Rio Grande Neurosciences, Inc. | Apparatus and method for electromagnetic treatment of neurological injury or condition caused by a stroke |
| US9433797B2 (en) | 2003-12-05 | 2016-09-06 | Rio Grande Neurosciences, Inc. | Apparatus and method for electromagnetic treatment of neurodegenerative conditions |
| US8961385B2 (en) | 2003-12-05 | 2015-02-24 | Ivivi Health Sciences, Llc | Devices and method for treatment of degenerative joint diseases with electromagnetic fields |
| US10350428B2 (en) | 2014-11-04 | 2019-07-16 | Endonovo Therapetics, Inc. | Method and apparatus for electromagnetic treatment of living systems |
| US9656096B2 (en) | 2003-12-05 | 2017-05-23 | Rio Grande Neurosciences, Inc. | Method and apparatus for electromagnetic enhancement of biochemical signaling pathways for therapeutics and prophylaxis in plants, animals and humans |
| US9415233B2 (en) | 2003-12-05 | 2016-08-16 | Rio Grande Neurosciences, Inc. | Apparatus and method for electromagnetic treatment of neurological pain |
| BRPI0506826A (pt) * | 2004-01-12 | 2007-05-29 | Univ Pennsylvania | métodos para melhorar especìfica e seletivamente a expressão de gene de proteìna(s) morfogenéticas ósseas no tecido, dispositivo e métodos de tratamento e método para se determinar um sinal seletivo que gera um campo elétrico |
| BRPI0509444A (pt) | 2004-04-19 | 2007-09-04 | Ivivi Technologies Inc | método para o tratamento eletromagnético de tecidos e células vivos através da intensificação da angiogênese e da neovascularização, aparelho de tratamento eletromagnético e dispositivo gerador de sinais eletromagnéticos |
| US7610100B2 (en) * | 2005-12-30 | 2009-10-27 | Boston Scientific Neuromodulation Corporation | Methods and systems for treating osteoarthritis |
| US20090018613A1 (en) * | 2006-08-02 | 2009-01-15 | Genestim, Llc | Regulation of vascular endothelial growth factor (vegf) gene expression in tissue via the application of electric and/or electromagnetic fields |
| WO2012045079A2 (en) | 2010-10-01 | 2012-04-05 | Ivivi Health Sciences, Llc | Method and apparatus for electromagnetic treatment of head cerebral and neural injury in animals and humans |
| US8343027B1 (en) | 2012-01-30 | 2013-01-01 | Ivivi Health Sciences, Llc | Methods and devices for providing electromagnetic treatment in the presence of a metal-containing implant |
| EP2703001A1 (en) * | 2012-08-26 | 2014-03-05 | XAX Kft. | Tumor vaccination |
| EP3131628A4 (en) | 2014-04-16 | 2017-11-22 | Ivivi Health Sciences, LLC | A two-part pulsed electromagnetic field applicator for application of therapeutic energy |
| WO2016129846A1 (ko) * | 2015-02-12 | 2016-08-18 | 최규환 | 토양 미생물을 이용한 음식물 쓰레기 발효 장치및 축분 비료화 장치, 이에 적합한 바이오필드 발생 장치, 이에 적합한 미생물 전지 및 이에 적합한 미생물 콘덴서 |
| US10806942B2 (en) | 2016-11-10 | 2020-10-20 | Qoravita LLC | System and method for applying a low frequency magnetic field to biological tissues |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4442846A (en) * | 1981-11-10 | 1984-04-17 | University Of Pennsylvania | Distributed port bone-piercing cathode for electrically stimulated osteogenesis |
| US4430999A (en) * | 1981-11-10 | 1984-02-14 | Trustees Of The University Of Pennsylvania | Osteogenesis stimulating cathode assembly for use with an internal fixation device |
| US4506674A (en) * | 1981-11-10 | 1985-03-26 | Trustees Of The University Of Pennsylvania | Method of stimulating osteogenesis with distributed port cathode |
| US4509520A (en) * | 1982-02-22 | 1985-04-09 | Biolectron, Inc. | Electrical stimulating apparatus |
| US4549547A (en) * | 1982-07-27 | 1985-10-29 | Trustees Of The University Of Pennsylvania | Implantable bone growth stimulator |
| US4487834A (en) * | 1982-09-17 | 1984-12-11 | Biolectron, Inc. | Electrical stimulation of articular chondrocytes |
| US4467809A (en) * | 1982-09-17 | 1984-08-28 | Biolectron, Inc. | Method for non-invasive electrical stimulation of epiphyseal plate growth |
| US4467808A (en) * | 1982-09-17 | 1984-08-28 | Biolectron, Inc. | Method for preventing and treating osteoporosis in a living body by using electrical stimulation non-invasively |
| US5269746A (en) * | 1982-12-20 | 1993-12-14 | Jacobson Jerry I | Therapeutic treatment of mammals for epilepsy and Parkinson's disease |
| US4535775A (en) * | 1983-02-10 | 1985-08-20 | Biolectron, Inc. | Method for treatment of non-union bone fractures by non-invasive electrical stimulation |
| IT1159024B (it) * | 1983-06-02 | 1987-02-25 | Ruggero Cadossi | Metodo e dispositivo per il trattamento di tessuti e cellule viventi mediante campi elettromagnetici pulsanti |
| US4600010A (en) * | 1984-10-04 | 1986-07-15 | Biolectron, Inc. | Electric stimulator and test instrument therefor |
| US4998532A (en) * | 1986-05-23 | 1991-03-12 | Lti Biomedical, Inc. | Portable electro-therapy system |
| US5014699A (en) * | 1986-05-23 | 1991-05-14 | Trustees Of The University Of Pennsylvania | Electromagnetic method and apparatus for healing living tissue |
| US6120502A (en) * | 1988-06-13 | 2000-09-19 | Michelson; Gary Karlin | Apparatus and method for the delivery of electrical current for interbody spinal arthrodesis |
| CA2004192A1 (en) * | 1988-11-30 | 1990-05-31 | Jerry I. Jacobson | Therapeutic treatment of mammals |
| US5038797A (en) * | 1990-02-20 | 1991-08-13 | Romaine, Incorporated | Electrical stimulation treatment device and method of use |
| US5273033A (en) * | 1991-09-19 | 1993-12-28 | Murray Electronics Associates Limited Partnership | Electrical stimulation for treatment of osteoarthritis |
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| US5374283A (en) * | 1993-12-01 | 1994-12-20 | Flick; A. Bart | Electrical therapeutic apparatus |
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| US6186940B1 (en) * | 1998-05-18 | 2001-02-13 | Robert N. Kirschbaum | Energized trace elements |
| US6292699B1 (en) * | 1999-01-29 | 2001-09-18 | Electro-Biology, Inc. | Direct current stimulation of spinal interbody fixation device |
| AU5124400A (en) * | 1999-04-29 | 2000-11-17 | North Shore Long Island Jewish Research Corporation | Method for inducing growth and enhancing survival of nervous tissue |
| DE19933719A1 (de) | 1999-07-19 | 2001-01-25 | Medigene Ag | Strukturprotein in Adeno-assoziiertem Virus mit veränderten chromatographischen Eigenschaften, seine Herstellung und Verwendung |
| US7022506B2 (en) * | 2000-02-23 | 2006-04-04 | The Trustees Of The University Of Pennsylvania | Method and device for treating osteoarthritis, cartilage disease, defects and injuries in the human knee |
| US6919205B2 (en) * | 2000-02-23 | 2005-07-19 | The Trustees Of The University Of Pennsylvania | Regulation of type II collagen gene expression using specific and selective electrical and electromagnetic signals |
| US7465566B2 (en) * | 2000-02-23 | 2008-12-16 | The Trustees Of The University Of Pennsylvania | Regulation of genes via application of specific and selective electrical and electromagnetic signals |
| US7130692B2 (en) * | 2000-02-23 | 2006-10-31 | The Trustees Of The University Of Pennsylvania | Portable electrotherapy device for treating osteoarthritis and other diseases, defects and injuries of the knee joint |
| US7465546B2 (en) * | 2000-02-23 | 2008-12-16 | The Trustees Of The University Of Pennsylvania | Regulation of transforming growth factor-beta (TGF-β) gene expression in living cells via the application of specific and selective electric and electromagnetic fields |
| US7429471B2 (en) | 2000-02-23 | 2008-09-30 | The Trustees Of The University Of Pennsylvania | Regulation of matrix metalloproteinase gene expression using specific and selective electrical and electromagnetic signals |
| US6485963B1 (en) * | 2000-06-02 | 2002-11-26 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Growth stimulation of biological cells and tissue by electromagnetic fields and uses thereof |
| EP1330193A4 (en) * | 2000-11-02 | 2006-03-22 | Keith L March | METHOD AND SYSTEM FOR MODULATING OSCILLATING SIGNALS FOR INCREASING BIOLOGICAL EFFECTS |
| US6485113B2 (en) * | 2001-03-08 | 2002-11-26 | Delphi Technologies, Inc. | Haptic braking method and system |
| AU2002318466A1 (en) * | 2001-07-03 | 2003-01-21 | The Trustees Of The University Of Pennsylvania | Device and method for electrically inducing osteogenesis in the spine |
| US7158835B2 (en) * | 2001-12-21 | 2007-01-02 | The Trustees Of The University Of Pennsylvania | Device for treating osteoporosis, hip and spine fractures and fusions with electric fields |
| US6955642B1 (en) * | 2002-11-26 | 2005-10-18 | Ebi, Lp | Pulsed electromagnetic field stimulation method and apparatus with improved dosing |
| AU2004291111A1 (en) * | 2003-11-14 | 2005-06-02 | The Trustees Of The University Of Pennsylvania | Method and device for treating osteoarthritis and cartilage disease, defects, and injuries in the human hip |
| BRPI0506826A (pt) * | 2004-01-12 | 2007-05-29 | Univ Pennsylvania | métodos para melhorar especìfica e seletivamente a expressão de gene de proteìna(s) morfogenéticas ósseas no tecido, dispositivo e métodos de tratamento e método para se determinar um sinal seletivo que gera um campo elétrico |
-
2003
- 2003-06-13 US US10/461,188 patent/US7429471B2/en not_active Expired - Lifetime
-
2004
- 2004-06-14 EP EP04755357A patent/EP1643953A4/en not_active Withdrawn
- 2004-06-14 WO PCT/US2004/019137 patent/WO2004112708A2/en not_active Ceased
- 2004-06-14 MX MXPA05013493A patent/MXPA05013493A/es not_active Application Discontinuation
- 2004-06-14 CA CA2529374A patent/CA2529374C/en not_active Expired - Lifetime
- 2004-06-14 AU AU2004249202A patent/AU2004249202A1/en not_active Abandoned
- 2004-06-14 JP JP2006533804A patent/JP2007502693A/ja active Pending
- 2004-06-14 KR KR1020057023972A patent/KR100856964B1/ko not_active Expired - Lifetime
- 2004-06-14 BR BRPI0411369-1A patent/BRPI0411369A/pt not_active IP Right Cessation
- 2004-06-14 CN CNA2004800201880A patent/CN1822807A/zh active Pending
-
2005
- 2005-12-12 EG EGNA2005000813 patent/EG24170A/xx active
- 2005-12-12 IL IL172508A patent/IL172508A0/en unknown
- 2005-12-13 CR CR8145A patent/CR8145A/es not_active Application Discontinuation
-
2006
- 2006-01-12 NO NO20060193A patent/NO20060193L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2007502693A (ja) | 2007-02-15 |
| WO2004112708A3 (en) | 2005-02-24 |
| EP1643953A2 (en) | 2006-04-12 |
| WO2004112708A2 (en) | 2004-12-29 |
| EP1643953A4 (en) | 2008-11-05 |
| IL172508A0 (en) | 2006-04-10 |
| CN1822807A (zh) | 2006-08-23 |
| CA2529374C (en) | 2010-01-26 |
| EG24170A (en) | 2008-09-14 |
| KR100856964B1 (ko) | 2008-09-04 |
| NO20060193L (no) | 2006-03-06 |
| MXPA05013493A (es) | 2007-03-15 |
| CA2529374A1 (en) | 2004-12-29 |
| KR20060024797A (ko) | 2006-03-17 |
| AU2004249202A1 (en) | 2004-12-29 |
| US20040138709A1 (en) | 2004-07-15 |
| US7429471B2 (en) | 2008-09-30 |
| BRPI0411369A (pt) | 2006-08-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal (granting procedure) |