CO5770094A1 - Composicion farmaceutica orodispersable para la administracion aoromucosa o sublingual de agomelatina - Google Patents
Composicion farmaceutica orodispersable para la administracion aoromucosa o sublingual de agomelatinaInfo
- Publication number
- CO5770094A1 CO5770094A1 CO06125383A CO06125383A CO5770094A1 CO 5770094 A1 CO5770094 A1 CO 5770094A1 CO 06125383 A CO06125383 A CO 06125383A CO 06125383 A CO06125383 A CO 06125383A CO 5770094 A1 CO5770094 A1 CO 5770094A1
- Authority
- CO
- Colombia
- Prior art keywords
- pharmaceutical composition
- composition according
- orodispersible
- core
- diluent
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 9
- 239000003085 diluting agent Substances 0.000 abstract 4
- YJYPHIXNFHFHND-UHFFFAOYSA-N agomelatine Chemical compound C1=CC=C(CCNC(C)=O)C2=CC(OC)=CC=C21 YJYPHIXNFHFHND-UHFFFAOYSA-N 0.000 abstract 3
- 229960002629 agomelatine Drugs 0.000 abstract 3
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- 239000012792 core layer Substances 0.000 abstract 2
- 239000010410 layer Substances 0.000 abstract 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- 229920002472 Starch Polymers 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000008107 starch Substances 0.000 abstract 1
- 235000019698 starch Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
- A61K9/2826—Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Nutrition Science (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Physiology (AREA)
- Psychiatry (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
? Composición farmacéutica de agomelatina orodispersable sólida recubierta, caracterizada por estar compuesta por: - un núcleo central o una capa central compuesta por agomelatina y excipientes que permiten la obtención de una formulación orodispersable; - un recubrimiento orodispersable. Composición farmacéutica conforme con la reivindicación 1, caracterizada por que la agomelatina se obtiene en forma cristalina II. Composición farmacéutica conforme con la reivindicación 1, caracterizada por que contiene un núcleo central. Composición farmacéutica conforme con la reivindicación 1, caracterizada por que contiene una capa central. Composición farmacéutica conforme con la reivindicación 1, caracterizada por que el núcleo o la capa central comprende un diluyente que imparte una propiedad orodispersable. Composición farmacéutica conforme con la reivindicación 5, caracterizada por que el diluyente utilizado en el núcleo central está basado en gránulos obtenidos por medio de coatomización de lactosa y almidón. Composición farmacéutica conforme con la reivindicación 1, caracterizada por que el núcleo o la capa central comprende un diluyente y un agente desintegrador. Composición farmacéutica conforme con la reivindicación 1, caracterizada por que el recubrimiento orodispersable comprende un diluyente que imparte una propiedad orodispersable.<EMI FILE="06125383_1" ID="1" IMF=JPEG HE=50 WI=50 >
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0512647A FR2894475B1 (fr) | 2005-12-14 | 2005-12-14 | Composition pharmaceutique orodispersible pour administra- -tion oromucosale ou sublinguale d'agomelatine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5770094A1 true CO5770094A1 (es) | 2007-06-29 |
Family
ID=36663148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO06125383A CO5770094A1 (es) | 2005-12-14 | 2006-12-14 | Composicion farmaceutica orodispersable para la administracion aoromucosa o sublingual de agomelatina |
Country Status (40)
| Country | Link |
|---|---|
| US (1) | US7892575B2 (es) |
| EP (1) | EP1800669B1 (es) |
| JP (2) | JP4996225B2 (es) |
| KR (3) | KR20070063420A (es) |
| CN (2) | CN101919800A (es) |
| AP (1) | AP2714A (es) |
| AR (1) | AR058332A1 (es) |
| AT (1) | ATE474561T1 (es) |
| AU (1) | AU2006252051B2 (es) |
| BR (1) | BRPI0605214A (es) |
| CA (1) | CA2571202C (es) |
| CO (1) | CO5770094A1 (es) |
| CR (1) | CR8788A (es) |
| CU (1) | CU23603B7 (es) |
| CY (1) | CY1110824T1 (es) |
| DE (1) | DE602006015592D1 (es) |
| DK (1) | DK1800669T3 (es) |
| EA (1) | EA013751B1 (es) |
| ES (1) | ES2348994T3 (es) |
| FR (1) | FR2894475B1 (es) |
| GE (1) | GEP20084509B (es) |
| GT (1) | GT200600500A (es) |
| HN (1) | HN2008000874A (es) |
| HR (1) | HRP20100517T1 (es) |
| IL (1) | IL180036A0 (es) |
| MA (1) | MA28722B1 (es) |
| MX (1) | MXPA06014605A (es) |
| MY (1) | MY143221A (es) |
| NO (1) | NO20065701L (es) |
| NZ (1) | NZ552025A (es) |
| PE (1) | PE20071030A1 (es) |
| PL (1) | PL1800669T3 (es) |
| PT (1) | PT1800669E (es) |
| RS (1) | RS51452B (es) |
| SG (1) | SG133531A1 (es) |
| SI (1) | SI1800669T1 (es) |
| TW (1) | TWI327911B (es) |
| UA (1) | UA86622C2 (es) |
| WO (1) | WO2007068829A1 (es) |
| ZA (1) | ZA200610511B (es) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008008801A2 (en) * | 2006-07-11 | 2008-01-17 | Mcneil Nutritionals, Llc | Solid oral dosage vitamin and mineral compositions |
| SI2238974T1 (sl) | 2009-04-09 | 2013-09-30 | E-Pharma Trento S.P.A. | Granulat za formuliranje orodisperzibilnih tablet |
| CN101781226B (zh) * | 2009-12-23 | 2012-03-28 | 天津泰普药品科技发展有限公司 | 阿戈美拉汀及其药物组合物 |
| WO2011111027A2 (en) | 2010-03-11 | 2011-09-15 | Dexcel Pharma Technologies Ltd. | Oral dispersible delayed release tablet formulation |
| CN101836966A (zh) * | 2010-05-27 | 2010-09-22 | 北京万全阳光医药科技有限公司 | 一种含有阿戈美拉汀的口腔崩解片 |
| CN101991559B (zh) * | 2010-11-25 | 2012-04-18 | 天津市汉康医药生物技术有限公司 | 一种稳定的阿戈美拉汀胶囊药物组合物 |
| US8426461B2 (en) | 2011-01-17 | 2013-04-23 | Takeda Pharmaceutical Company Limited | Orally dispersible tablet |
| KR20140014134A (ko) | 2011-01-17 | 2014-02-05 | 다케다 야쿠힌 고교 가부시키가이샤 | 구강내 분산정 |
| FR2978916B1 (fr) | 2011-08-10 | 2013-07-26 | Servier Lab | Composition pharmaceutique solide pour administration buccale d'agomelatine |
| EP2765985A1 (en) | 2011-10-14 | 2014-08-20 | Takeda Pharmaceutical Company Limited | Orally dispersible tablet |
| CN103169669B (zh) * | 2011-12-26 | 2015-06-17 | 中国人民解放军军事医学科学院毒物药物研究所 | 阿戈美拉汀包衣微丸以及可在口中分散的药物组合物 |
| CN102552211B (zh) * | 2012-02-16 | 2013-07-17 | 福建广生堂药业股份有限公司 | 一种阿戈美拉汀的制剂组合物及其制备方法 |
| FR3000896B1 (fr) * | 2013-01-14 | 2016-08-26 | Philippe Perovitch | Forme galenique pour l'administration de principe(s) actif(s) permettant l'induction acceleree du sommeil et/ou le traitement des troubles du sommeil |
| FR3001894A1 (fr) * | 2013-02-08 | 2014-08-15 | Servier Lab | Composition pharmaceutique solide pour administration buccale d'agomelatine |
| HUE036989T2 (hu) * | 2013-06-06 | 2018-08-28 | Zentiva Ks | Agomelatin készítmény, amely agomelatint ko-kristály formájában tartalmaz |
| EP2810647A1 (en) | 2013-06-06 | 2014-12-10 | Zentiva, a.s. | Pharmaceutical formulations comprising agomelatine in the form of agomelatine co-crystal with an organic acid |
| CN105007904A (zh) * | 2014-02-07 | 2015-10-28 | 科学实验室药物公司 | 全天然无毒舌下药物递送系统 |
| CN104523639B (zh) * | 2014-12-11 | 2017-03-22 | 扬子江药业集团四川海蓉药业有限公司 | 一种阿戈美拉汀片剂及其制备方法 |
| MX2022007331A (es) * | 2019-12-20 | 2022-07-27 | Lts Lohmann Therapie Systeme Ag | Sistema terapéutico transmucosal que contiene agomelatina. |
| CN113597303B (zh) * | 2019-12-20 | 2022-11-18 | 罗曼治疗系统股份公司 | 含有阿戈美拉汀的经粘膜治疗系统 |
| NL2031331B1 (en) | 2022-03-18 | 2023-09-29 | Plethora Therapeutics B V | Transmucosal delivery of a short-acting psychedelic compound |
| NL2031332B1 (en) | 2022-03-18 | 2023-09-29 | Plethora Therapeutics B V | Transmucosal delivery of psychoactive compounds |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5762963A (en) * | 1995-06-07 | 1998-06-09 | Emory University | Method and compositions for controlling oral and pharyngeal pain using capsaicinoids |
| ATE371439T1 (de) * | 2000-07-27 | 2007-09-15 | Roquette Freres | Granulat bestehend aus stärke und laktose |
| JP2002338500A (ja) * | 2001-03-15 | 2002-11-27 | Yamanouchi Pharmaceut Co Ltd | 苦味を低減した口腔内速崩壊錠および苦み低減化方法 |
| US6723348B2 (en) * | 2001-11-16 | 2004-04-20 | Ethypharm | Orodispersible tablets containing fexofenadine |
| FR2834890B1 (fr) * | 2002-01-23 | 2004-02-27 | Servier Lab | Composition pharmaceutique orodispersible d'agomelatine |
| FR2857263B1 (fr) * | 2003-07-09 | 2005-09-09 | Sanofi Synthelabo | Nouvelle composition pharmaceutique solide comprenant de l'amisulpride |
| FR2866335B1 (fr) * | 2004-02-13 | 2006-05-26 | Servier Lab | Nouveau procede de synthese de l'agomelatine |
-
2005
- 2005-12-14 FR FR0512647A patent/FR2894475B1/fr not_active Expired - Fee Related
-
2006
- 2006-12-05 AP AP2006003844A patent/AP2714A/xx active
- 2006-12-05 CR CR8788A patent/CR8788A/es unknown
- 2006-12-08 KR KR1020060124485A patent/KR20070063420A/ko not_active Ceased
- 2006-12-11 NO NO20065701A patent/NO20065701L/no not_active Application Discontinuation
- 2006-12-11 PE PE2006001582A patent/PE20071030A1/es not_active Application Discontinuation
- 2006-12-12 CU CU20060243A patent/CU23603B7/es not_active IP Right Cessation
- 2006-12-12 GE GEAP20069757A patent/GEP20084509B/en unknown
- 2006-12-13 EA EA200602104A patent/EA013751B1/ru not_active IP Right Cessation
- 2006-12-13 MX MXPA06014605A patent/MXPA06014605A/es active IP Right Grant
- 2006-12-13 TW TW095146707A patent/TWI327911B/zh not_active IP Right Cessation
- 2006-12-13 NZ NZ552025A patent/NZ552025A/en not_active IP Right Cessation
- 2006-12-13 MY MYPI20064671A patent/MY143221A/en unknown
- 2006-12-13 BR BRPI0605214-2A patent/BRPI0605214A/pt not_active IP Right Cessation
- 2006-12-13 IL IL180036A patent/IL180036A0/en unknown
- 2006-12-13 AR ARP060105481A patent/AR058332A1/es not_active Application Discontinuation
- 2006-12-13 GT GT200600500A patent/GT200600500A/es unknown
- 2006-12-13 UA UAA200613196A patent/UA86622C2/ru unknown
- 2006-12-14 EP EP06291919A patent/EP1800669B1/fr active Active
- 2006-12-14 CO CO06125383A patent/CO5770094A1/es active IP Right Grant
- 2006-12-14 ZA ZA200610511A patent/ZA200610511B/xx unknown
- 2006-12-14 JP JP2006336625A patent/JP4996225B2/ja not_active Expired - Fee Related
- 2006-12-14 CA CA2571202A patent/CA2571202C/fr not_active Expired - Fee Related
- 2006-12-14 PL PL06291919T patent/PL1800669T3/pl unknown
- 2006-12-14 SI SI200630801T patent/SI1800669T1/sl unknown
- 2006-12-14 ES ES06291919T patent/ES2348994T3/es active Active
- 2006-12-14 PT PT06291919T patent/PT1800669E/pt unknown
- 2006-12-14 DK DK06291919.6T patent/DK1800669T3/da active
- 2006-12-14 AT AT06291919T patent/ATE474561T1/de active
- 2006-12-14 CN CN2010102121892A patent/CN101919800A/zh active Pending
- 2006-12-14 AU AU2006252051A patent/AU2006252051B2/en not_active Ceased
- 2006-12-14 MA MA29530A patent/MA28722B1/fr unknown
- 2006-12-14 US US11/638,960 patent/US7892575B2/en not_active Expired - Fee Related
- 2006-12-14 RS RSP-2010/0411A patent/RS51452B/sr unknown
- 2006-12-14 WO PCT/FR2006/002727 patent/WO2007068829A1/fr not_active Ceased
- 2006-12-14 SG SG200608701-9A patent/SG133531A1/en unknown
- 2006-12-14 CN CN2006101670701A patent/CN1981752B/zh not_active Expired - Fee Related
- 2006-12-14 DE DE602006015592T patent/DE602006015592D1/de active Active
-
2008
- 2008-06-12 HN HN2008000874A patent/HN2008000874A/es unknown
- 2008-11-21 KR KR1020080116206A patent/KR101013667B1/ko not_active Expired - Fee Related
-
2009
- 2009-12-30 KR KR1020090134061A patent/KR20100012858A/ko not_active Withdrawn
-
2010
- 2010-09-21 HR HR20100517T patent/HRP20100517T1/hr unknown
- 2010-10-07 CY CY20101100898T patent/CY1110824T1/el unknown
-
2011
- 2011-12-22 JP JP2011281211A patent/JP2012092132A/ja active Pending
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