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CO5280139A1 - PROCEDURE TO OBTAIN PLANTS WITH A GREATER CONTENT OF FLAVONOIDS AND PHENOLIC COMPOUNDS - Google Patents

PROCEDURE TO OBTAIN PLANTS WITH A GREATER CONTENT OF FLAVONOIDS AND PHENOLIC COMPOUNDS

Info

Publication number
CO5280139A1
CO5280139A1 CO00044702A CO00044702A CO5280139A1 CO 5280139 A1 CO5280139 A1 CO 5280139A1 CO 00044702 A CO00044702 A CO 00044702A CO 00044702 A CO00044702 A CO 00044702A CO 5280139 A1 CO5280139 A1 CO 5280139A1
Authority
CO
Colombia
Prior art keywords
flavonoids
procedure
phenolic compounds
obtain plants
greater content
Prior art date
Application number
CO00044702A
Other languages
Spanish (es)
Inventor
Wilhem Rademacher
Klaus Kramer
Jurgen Schweden
Karin Herbers
Original Assignee
Basf Aktiengesellsschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Aktiengesellsschaft filed Critical Basf Aktiengesellsschaft
Publication of CO5280139A1 publication Critical patent/CO5280139A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H1/00—Processes for modifying genotypes ; Plants characterised by associated natural traits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9771—Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/825—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving pigment biosynthesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/86—Products or compounds obtained by genetic engineering

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)

Abstract

Procedimiento para elevar el contenido de flavonoides y de constituyentes fenólicos en las plantas, caracterizado porque mediante métodos de genética molecular se obtiene una planta en la cual se ha reducido la actividad de la enzima flavanón-3-hidroxilasa.Procedure for raising the content of flavonoids and phenolic constituents in plants, characterized in that by means of molecular genetic methods a plant is obtained in which the activity of the enzyme flavanon-3-hydroxylase has been reduced.

CO00044702A 1999-06-17 2000-06-15 PROCEDURE TO OBTAIN PLANTS WITH A GREATER CONTENT OF FLAVONOIDS AND PHENOLIC COMPOUNDS CO5280139A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19927574A DE19927574A1 (en) 1999-06-17 1999-06-17 Increasing content of flavonoids and phenols in plants, useful for e.g. preventing cardiovascular disease, by reducing activity of flavanone-3-hydroxylase

Publications (1)

Publication Number Publication Date
CO5280139A1 true CO5280139A1 (en) 2003-05-30

Family

ID=7911499

Family Applications (1)

Application Number Title Priority Date Filing Date
CO00044702A CO5280139A1 (en) 1999-06-17 2000-06-15 PROCEDURE TO OBTAIN PLANTS WITH A GREATER CONTENT OF FLAVONOIDS AND PHENOLIC COMPOUNDS

Country Status (16)

Country Link
EP (1) EP1102855A1 (en)
JP (1) JP2003503032A (en)
KR (1) KR20020068256A (en)
CN (1) CN1314943A (en)
AR (1) AR024381A1 (en)
AU (1) AU5970400A (en)
BG (1) BG105246A (en)
BR (1) BR0006869A (en)
CA (1) CA2340319A1 (en)
CO (1) CO5280139A1 (en)
DE (1) DE19927574A1 (en)
HU (1) HUP0103307A2 (en)
IL (1) IL141173A0 (en)
PL (1) PL346059A1 (en)
WO (1) WO2000078980A1 (en)
ZA (1) ZA200101328B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100642939B1 (en) * 2003-02-11 2006-11-10 학교법인 신천학원 Cosmetic soap containing plum extract and extraction method thereof
KR100553522B1 (en) * 2004-02-06 2006-02-20 학교법인 건국대학교 Isoflavone-reinforced germinated green bean and its manufacturing method
WO2005074710A1 (en) * 2004-02-06 2005-08-18 Konkuk University Industrial Coorperation Corp Sprouted bean containing high concentration of isoflavone and the preparing method thereof
KR100663669B1 (en) * 2005-05-18 2007-01-02 금호석유화학 주식회사 Transformed Rice Produces High Concentration of Flavonoids in the Breast Milk
EP2429311A4 (en) * 2009-04-21 2014-03-26 Haas John I Animal feed compositions and feeding methods
EP2286669A1 (en) * 2009-07-29 2011-02-23 Nestec S.A. Flavanones-containing food compositions
WO2013183177A1 (en) * 2012-06-07 2013-12-12 株式会社燦樹 Garlic egg yolk composition and method for producing same
KR101415687B1 (en) * 2012-09-19 2014-07-10 농업회사법인 호트팜 주식회사 Multiple Propagation Methods of in vitro Plantlets Derived from Node Cultures of Aronia using Tissue Culture Techniques
WO2015140589A1 (en) * 2014-03-20 2015-09-24 Hongkong Chuanghui International Limited Method for preparation multifunctional liquid medicament from vegetable feedstock, and the product produced by the method
CN105985936A (en) * 2015-02-02 2016-10-05 中国人民解放军第二军医大学 Erigeron breviscapus flavanone-3-hydroxylase as well as coding gene and application thereof
CN111875689B (en) * 2020-08-07 2022-02-01 山东玄康种业科技有限公司 Method for creating male sterile line by using tomato green stem close linkage marker
US20230321030A1 (en) 2020-08-25 2023-10-12 Otsuka Pharmaceutical Co., Ltd. Kaempferol aglycone-containing extract
CN112391362B (en) * 2020-11-04 2022-07-05 江南大学 Flavonoid 3β-hydroxylase mutant with improved catalytic activity and its application

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5432068A (en) * 1990-06-12 1995-07-11 Pioneer Hi-Bred International, Inc. Control of male fertility using externally inducible promoter sequences
WO1993018142A1 (en) * 1992-03-09 1993-09-16 Washington State University Research Foundation Methods for the regulation of plant fertility
GB9525459D0 (en) * 1995-12-13 1996-02-14 Zeneca Ltd Genetic control of fruit ripening
EP1066385A1 (en) * 1998-02-25 2001-01-10 E.I. Du Pont De Nemours & Company Incorporated Plant flavanone-3-hydroxylase
WO2000050613A2 (en) * 1999-02-22 2000-08-31 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Transgenic plants and method for transforming carnations

Also Published As

Publication number Publication date
ZA200101328B (en) 2002-02-18
BG105246A (en) 2001-10-31
JP2003503032A (en) 2003-01-28
DE19927574A1 (en) 2000-12-21
KR20020068256A (en) 2002-08-27
CN1314943A (en) 2001-09-26
HUP0103307A2 (en) 2001-12-28
IL141173A0 (en) 2002-02-10
EP1102855A1 (en) 2001-05-30
PL346059A1 (en) 2002-01-14
WO2000078980A1 (en) 2000-12-28
BR0006869A (en) 2001-08-07
CA2340319A1 (en) 2000-12-28
AR024381A1 (en) 2002-10-02
AU5970400A (en) 2001-01-09

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