CO2018010827A2 - Anti-complement factor bb antibodies and uses of these - Google Patents
Anti-complement factor bb antibodies and uses of theseInfo
- Publication number
- CO2018010827A2 CO2018010827A2 CONC2018/0010827A CO2018010827A CO2018010827A2 CO 2018010827 A2 CO2018010827 A2 CO 2018010827A2 CO 2018010827 A CO2018010827 A CO 2018010827A CO 2018010827 A2 CO2018010827 A2 CO 2018010827A2
- Authority
- CO
- Colombia
- Prior art keywords
- antibodies
- complement
- complement factor
- treatment
- present description
- Prior art date
Links
- 230000002391 anti-complement effect Effects 0.000 title 1
- 108010008730 anticomplement Proteins 0.000 title 1
- 230000000295 complement effect Effects 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 208000035475 disorder Diseases 0.000 abstract 2
- 230000001404 mediated effect Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente descripción proporciona anticuerpos¬ anti-factor Bb del complemento y composiciones que comprenden los anticuerpos. Los anticuerpos anti-Bb son útiles para el tratamiento de trastornos mediados¬ por el complemento. La presente descripción proporciona métodos para el tratamiento de trastornos mediados ¬por el complemento.The present description provides complement anti-Bb antibody antibodies and compositions comprising the antibodies. Anti-Bb antibodies are useful for the treatment of complement-mediated disorders. The present description provides methods for the treatment of disorders mediated by complement.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662317897P | 2016-04-04 | 2016-04-04 | |
| PCT/US2017/025784 WO2017176651A1 (en) | 2016-04-04 | 2017-04-03 | Anti-complement factor bb antibodies and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO2018010827A2 true CO2018010827A2 (en) | 2018-11-22 |
Family
ID=60000646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CONC2018/0010827A CO2018010827A2 (en) | 2016-04-04 | 2018-10-09 | Anti-complement factor bb antibodies and uses of these |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US10934347B2 (en) |
| EP (1) | EP3452510A4 (en) |
| JP (3) | JP6967528B2 (en) |
| KR (2) | KR20240096672A (en) |
| CN (2) | CN109563158B (en) |
| AU (2) | AU2017246794B2 (en) |
| BR (1) | BR112018070357A2 (en) |
| CA (1) | CA3019332A1 (en) |
| CL (1) | CL2018002810A1 (en) |
| CO (1) | CO2018010827A2 (en) |
| CR (1) | CR20180529A (en) |
| DO (1) | DOP2018000219A (en) |
| EA (1) | EA201892225A1 (en) |
| EC (1) | ECSP18082302A (en) |
| IL (3) | IL262010B (en) |
| MA (1) | MA44878A (en) |
| MX (2) | MX2018012176A (en) |
| MY (1) | MY194603A (en) |
| PE (1) | PE20190209A1 (en) |
| PH (1) | PH12018502137A1 (en) |
| SG (1) | SG11201808525UA (en) |
| TN (1) | TN2018000341A1 (en) |
| WO (1) | WO2017176651A1 (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE044869T2 (en) | 2010-07-28 | 2019-12-30 | Gliknik Inc | Natural human protein fragments for the preparation of fusion protein sequences of multimerized immunoglobulin FC compositions |
| PT3325011T (en) | 2015-07-24 | 2021-01-27 | Gliknik Inc | HUMAN PROTEIN FRAGMENT FUSION PROTEINS TO CREATE MULTIMERIZED CF IMMUNOGLOBULIN COMPOSITIONS ORDERED WITH IMPROVED COMPLEMENT BINDING |
| MA44878A (en) | 2016-04-04 | 2019-03-13 | Bioverativ Usa Inc | COMPLEMENT ANTI-FACTOR BB ANTIBODIES AND USES OF THEM |
| IL266988B2 (en) * | 2016-12-09 | 2024-11-01 | Gliknik Inc | Methods for the treatment of inflammatory disorders with multivalent FC compounds |
| CN110177802A (en) | 2016-12-09 | 2019-08-27 | 格利克尼克股份有限公司 | Manufacturing Optimization of Multimerized Stradomer GL-2045 |
| CA3050692A1 (en) * | 2017-01-17 | 2018-07-26 | The Texas A&M University System | Endolysosomal targeting conjugates for improved delivery of cargo molecules to the endolysosomal compartment of target cells |
| JP7369121B2 (en) * | 2017-10-11 | 2023-10-25 | バイオベラティブ・ユーエスエイ・インコーポレイテッド | How to induce complement activity |
| CN111727243A (en) | 2017-12-19 | 2020-09-29 | 北卡罗来纳-查佩尔山大学 | Methods and compositions for delivering viral vectors across the blood-brain barrier |
| KR20220042128A (en) * | 2019-06-27 | 2022-04-04 | 베르조 테라퓨틱스, 아이엔씨. | Anti-CD53 compositions and methods for modulating myeloid cell inflammatory phenotype, and uses thereof |
| US11820814B2 (en) * | 2019-07-17 | 2023-11-21 | Gemini Therapeutics Sub, Inc. | Factor H potentiating antibodies and uses thereof |
| US20230050339A1 (en) * | 2020-02-18 | 2023-02-16 | Children's Hospital Medical Center | Compositions and methods for treating liver disease |
| KR20230004686A (en) * | 2020-04-20 | 2023-01-06 | 젠자임 코포레이션 | Humanized anti-complement factor Bb antibodies and uses thereof |
| CA3193488A1 (en) | 2020-09-23 | 2022-03-31 | Jason Allan Wiles | Pharmaceutical compounds for the treatment of complement mediated disorders |
Family Cites Families (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US4866132A (en) | 1986-04-17 | 1989-09-12 | The Research Foundation Of State University Of New York | Novel radiopaque barium polymer complexes, compositions of matter and articles prepared therefrom |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| JPH02500329A (en) | 1987-05-21 | 1990-02-08 | クリエイテイブ・バイオマリキユールズ・インコーポレーテツド | Targeted multifunctional protein |
| US5256334A (en) | 1988-09-08 | 1993-10-26 | The Research Foundation Of The State University Of New York | Homogeneous radiopaque polymer-organobismuth composites |
| DE3920358A1 (en) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | BISPECIFIC AND OLIGO-SPECIFIC, MONO- AND OLIGOVALENT ANTI-BODY CONSTRUCTS, THEIR PRODUCTION AND USE |
| US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
| US5595732A (en) | 1991-03-25 | 1997-01-21 | Hoffmann-La Roche Inc. | Polyethylene-protein conjugates |
| DE69233482T2 (en) | 1991-05-17 | 2006-01-12 | Merck & Co., Inc. | Method for reducing the immunogenicity of antibody variable domains |
| CA2115742A1 (en) | 1991-08-20 | 1993-03-04 | Ronald G. Crystal | Adenovirus mediated transfer of genes to the gastrointestinal tract |
| EP0605522B1 (en) | 1991-09-23 | 1999-06-23 | Medical Research Council | Methods for the production of humanized antibodies |
| US5252479A (en) | 1991-11-08 | 1993-10-12 | Research Corporation Technologies, Inc. | Safe vector for gene therapy |
| ATE297465T1 (en) | 1991-11-25 | 2005-06-15 | Enzon Inc | METHOD FOR PRODUCING MULTIVALENT ANTIGEN-BINDING PROTEINS |
| FR2688514A1 (en) | 1992-03-16 | 1993-09-17 | Centre Nat Rech Scient | Defective recombinant adenoviruses expressing cytokines and antitumour drugs containing them |
| CA2592997A1 (en) | 1992-12-03 | 1994-06-09 | Genzyme Corporation | Pseudo-adenovirus vectors |
| US5346981A (en) | 1993-01-13 | 1994-09-13 | Miles Inc. | Radiopaque polyurethanes |
| DE614989T1 (en) | 1993-02-17 | 1995-09-28 | Morphosys Proteinoptimierung | Method for in vivo selection of ligand binding proteins. |
| WO1995000655A1 (en) | 1993-06-24 | 1995-01-05 | Mc Master University | Adenovirus vectors for gene therapy |
| WO1995011984A2 (en) | 1993-10-25 | 1995-05-04 | Canji, Inc. | Recombinant adenoviral vector and methods of use |
| US5643575A (en) | 1993-10-27 | 1997-07-01 | Enzon, Inc. | Non-antigenic branched polymer conjugates |
| WO1996017951A2 (en) | 1994-12-09 | 1996-06-13 | Rpms Technology Limited | Identification of genes responsible for in vivo survival of microorganisms |
| US5939045A (en) | 1994-12-22 | 1999-08-17 | Nissan Chemical Industries, Ltd. | Organic bismuth derivatives for X-ray imaging |
| US5670477A (en) | 1995-04-20 | 1997-09-23 | Joseph F. Poduslo | Method to enhance permeability of the blood/brain blood/nerve bariers to therapeutic agents |
| EP0904107B1 (en) | 1996-03-18 | 2004-10-20 | Board Of Regents, The University Of Texas System | Immunoglobin-like domains with increased half lives |
| ES2166097T5 (en) | 1996-08-27 | 2007-03-16 | Novartis Vaccines And Diagnostics, Inc. | NEISSERIA GLICOCONJUGADOS OF SEROGROUP B MENINGITIDIS AND PROCEDURES FOR USE. |
| WO1998023289A1 (en) | 1996-11-27 | 1998-06-04 | The General Hospital Corporation | MODULATION OF IgG BINDING TO FcRn |
| US6080849A (en) | 1997-09-10 | 2000-06-27 | Vion Pharmaceuticals, Inc. | Genetically modified tumor-targeted bacteria with reduced virulence |
| AU741166B2 (en) | 1997-12-12 | 2001-11-22 | Macromed, Inc. | Heterofunctionalized star-shaped poly(ethylene glycols) for protein modification |
| US6737056B1 (en) | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
| PT1355919E (en) | 2000-12-12 | 2011-03-02 | Medimmune Llc | Molecules with extended half-lives, compositions and uses thereof |
| GB0105924D0 (en) | 2001-03-09 | 2001-04-25 | Microscience Ltd | Promoter |
| PL1713503T3 (en) | 2004-02-10 | 2014-02-28 | Univ Colorado Regents | Inhibition of factor b, the alternative complement pathway and methods related thereto |
| BRPI0512235A (en) | 2004-06-18 | 2008-02-19 | Ambrx Inc | antigen-binding polypeptides and their uses |
| US20090016959A1 (en) | 2005-02-18 | 2009-01-15 | Richard Beliveau | Delivery of antibodies to the central nervous system |
| US8741260B2 (en) | 2005-10-07 | 2014-06-03 | Armagen Technologies, Inc. | Fusion proteins for delivery of GDNF to the CNS |
| KR20180002911A (en) | 2005-11-04 | 2018-01-08 | 제넨테크, 인크. | Use of complement pathway inhibitors to treat ocular diseases |
| SI2913343T1 (en) * | 2005-12-20 | 2019-01-31 | Sbi Biotech Co., Ltd. | Anti-ILT7 antibody |
| CN101970002B (en) * | 2007-08-27 | 2016-05-18 | 诺福麦德治疗学股份有限公司 | By the method for inhibiting complement activation with factor bb specific antibodies |
| AU2008323939A1 (en) * | 2007-11-08 | 2009-05-14 | Genentech, Inc. | Anti-factor B antibodies and their uses |
| WO2009082624A2 (en) * | 2007-12-10 | 2009-07-02 | Zymogenetics, Inc. | Antagonists of il-17a, il-17f, and il-23 and methods of using the same |
| BRPI0923283A2 (en) | 2008-12-05 | 2017-06-06 | Angiochem Inc | therapeutic peptide conjugates and uses thereof |
| EP2483307A1 (en) * | 2009-09-29 | 2012-08-08 | Fraunhofer USA, Inc. | Influenza hemagglutinin antibodies, compositions, and related methods |
| WO2013063395A1 (en) | 2011-10-27 | 2013-05-02 | Nkt Therapeutics Inc. | Humanized antibodies to inkt |
| BR112014020826A8 (en) * | 2012-02-24 | 2017-09-19 | Stem Centrx Inc | ANTIBODY SPECIFICALLY BINDING TO AN Epitope, NUCLEIC ACID, VECTOR OR HOST CELL, DRUG CONJUGATE ANTIBODY, PHARMACEUTICAL COMPOSITION COMPRISING SAID ANTIBODY, USE THEREOF, KIT AND METHOD OF PREPARATION OF THE CONJUGATE |
| AU2013243570B2 (en) * | 2012-04-03 | 2017-12-14 | Novelmed Therapeutics, Inc. | Humanized and chimeric anti-factor Bb antibodies and uses thereof |
| WO2014044793A2 (en) | 2012-09-20 | 2014-03-27 | Max-Delbrück-Centrum für Molekulare Medizin | Cd22-binding peptides |
| LT2914291T (en) * | 2012-11-02 | 2022-06-10 | Bioverativ Usa Inc. | ANTIBODIES TO COMPLEMENT C1S AND METHODS OF THEIR USE |
| EP3556400A1 (en) | 2013-02-22 | 2019-10-23 | AbbVie Stemcentrx LLC | Method of making antidll3-antibody pbd conjugates |
| US9260527B2 (en) | 2013-03-15 | 2016-02-16 | Sdix, Llc | Anti-human CXCR4 antibodies and methods of making same |
| US10035847B2 (en) | 2013-10-02 | 2018-07-31 | The Rockefeller University | Amyloid protofibril antibodies and methods of use thereof |
| SG10202104175YA (en) | 2014-02-27 | 2021-06-29 | Allergan Inc | COMPLEMENT FACTOR Bb ANTIBODIES |
| MX383464B (en) | 2015-07-13 | 2025-03-14 | Cytomx Therapeutics Inc | ANTI-PD-1 ANTIBODIES, ACTIVATABLE ANTI-PD-1 ANTIBODIES, AND METHODS OF USING THE SAME. |
| MA44878A (en) | 2016-04-04 | 2019-03-13 | Bioverativ Usa Inc | COMPLEMENT ANTI-FACTOR BB ANTIBODIES AND USES OF THEM |
| JP7369121B2 (en) | 2017-10-11 | 2023-10-25 | バイオベラティブ・ユーエスエイ・インコーポレイテッド | How to induce complement activity |
| KR20230004686A (en) | 2020-04-20 | 2023-01-06 | 젠자임 코포레이션 | Humanized anti-complement factor Bb antibodies and uses thereof |
-
2017
- 2017-04-03 MA MA044878A patent/MA44878A/en unknown
- 2017-04-03 BR BR112018070357-5A patent/BR112018070357A2/en active Search and Examination
- 2017-04-03 MY MYPI2018001682A patent/MY194603A/en unknown
- 2017-04-03 CN CN201780029742.9A patent/CN109563158B/en active Active
- 2017-04-03 US US16/091,447 patent/US10934347B2/en active Active
- 2017-04-03 SG SG11201808525UA patent/SG11201808525UA/en unknown
- 2017-04-03 EA EA201892225A patent/EA201892225A1/en unknown
- 2017-04-03 CA CA3019332A patent/CA3019332A1/en active Pending
- 2017-04-03 IL IL262010A patent/IL262010B/en unknown
- 2017-04-03 AU AU2017246794A patent/AU2017246794B2/en active Active
- 2017-04-03 TN TNP/2018/000341A patent/TN2018000341A1/en unknown
- 2017-04-03 EP EP17779607.5A patent/EP3452510A4/en active Pending
- 2017-04-03 IL IL311675A patent/IL311675A/en unknown
- 2017-04-03 KR KR1020247018546A patent/KR20240096672A/en active Pending
- 2017-04-03 PE PE2018001946A patent/PE20190209A1/en unknown
- 2017-04-03 JP JP2018552076A patent/JP6967528B2/en active Active
- 2017-04-03 MX MX2018012176A patent/MX2018012176A/en unknown
- 2017-04-03 CR CR20180529A patent/CR20180529A/en unknown
- 2017-04-03 KR KR1020187031483A patent/KR102673420B1/en active Active
- 2017-04-03 CN CN202210862505.3A patent/CN116790614A/en active Pending
- 2017-04-03 WO PCT/US2017/025784 patent/WO2017176651A1/en not_active Ceased
- 2017-04-03 IL IL295288A patent/IL295288B2/en unknown
-
2018
- 2018-10-03 CL CL2018002810A patent/CL2018002810A1/en unknown
- 2018-10-04 PH PH12018502137A patent/PH12018502137A1/en unknown
- 2018-10-04 DO DO2018000219A patent/DOP2018000219A/en unknown
- 2018-10-04 MX MX2023007149A patent/MX2023007149A/en unknown
- 2018-10-09 CO CONC2018/0010827A patent/CO2018010827A2/en unknown
- 2018-10-31 EC ECSENADI201882302A patent/ECSP18082302A/en unknown
-
2021
- 2021-01-19 US US17/151,860 patent/US11851482B2/en active Active
- 2021-09-10 JP JP2021147485A patent/JP7326393B2/en active Active
-
2023
- 2023-08-02 JP JP2023126155A patent/JP2023139289A/en active Pending
- 2023-11-08 US US18/504,416 patent/US20240228599A1/en active Pending
-
2024
- 2024-09-30 AU AU2024224000A patent/AU2024224000A1/en active Pending
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