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CO2017001076A2 - Antihyperalgesic, anti-allodinic and anti-inflammatory pharmaceutical compositions containing pregabalin and meloxicam - Google Patents

Antihyperalgesic, anti-allodinic and anti-inflammatory pharmaceutical compositions containing pregabalin and meloxicam

Info

Publication number
CO2017001076A2
CO2017001076A2 CONC2017/0001076A CO2017001076A CO2017001076A2 CO 2017001076 A2 CO2017001076 A2 CO 2017001076A2 CO 2017001076 A CO2017001076 A CO 2017001076A CO 2017001076 A2 CO2017001076 A2 CO 2017001076A2
Authority
CO
Colombia
Prior art keywords
antihyperalgesic
pharmaceutical compositions
meloxicam
allodinic
compositions containing
Prior art date
Application number
CONC2017/0001076A
Other languages
Spanish (es)
Inventor
Armenta Maria Elena Garcia
Ochoa Victor Guillermo Alvarez
Original Assignee
Pptm Int S A R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53938368&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO2017001076(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pptm Int S A R L filed Critical Pptm Int S A R L
Publication of CO2017001076A2 publication Critical patent/CO2017001076A2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a una novedosa combinación farmacéutica sinérgica de un agente antihiperalgésico, antialodínico y un agente antiinflamatorio, en donde el agente antihiperalgésico, antialodínico es Pregabalina, y el agente antiinflamatorio es Meloxicam. La presente invención además está dirigida a composiciones farmacéuticas que comprenden dicha combinación, y al uso de dicha combinación y composiciones farmacéuticas para la prevención y/o tratamiento del dolor neuropático ocasionado por diversas etiologías.The present invention relates to a novel synergistic pharmaceutical combination of an antihyperalgesic, anti-allodynic agent and an anti-inflammatory agent, wherein the antihyperalgesic, anti-allodynic agent is Pregabalin, and the anti-inflammatory agent is Meloxicam. The present invention is further directed to pharmaceutical compositions comprising said combination, and to the use of said combination and pharmaceutical compositions for the prevention and / or treatment of neuropathic pain caused by various etiologies.

CONC2017/0001076A 2014-07-07 2017-02-06 Antihyperalgesic, anti-allodinic and anti-inflammatory pharmaceutical compositions containing pregabalin and meloxicam CO2017001076A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
MX2014008336A MX2014008336A (en) 2014-07-07 2014-07-07 Antihyperalgesic, antiallodynic and anti-inflammatory pharmacological combination, pharmaceutical compositions containing same and use thereof for treating neuropatic pain.
PCT/IB2015/055127 WO2016005897A1 (en) 2014-07-07 2015-07-07 Combination of pregabalin and meloxicam for the treatment of neuropathic pain

Publications (1)

Publication Number Publication Date
CO2017001076A2 true CO2017001076A2 (en) 2017-05-31

Family

ID=53938368

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2017/0001076A CO2017001076A2 (en) 2014-07-07 2017-02-06 Antihyperalgesic, anti-allodinic and anti-inflammatory pharmaceutical compositions containing pregabalin and meloxicam

Country Status (5)

Country Link
BR (1) BR112017000359A2 (en)
CO (1) CO2017001076A2 (en)
MX (1) MX2014008336A (en)
PE (1) PE20171140A1 (en)
WO (1) WO2016005897A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3687520A4 (en) * 2017-09-28 2021-06-23 Nevakar, Inc Fixed dose combination formulations for treating pain
MX388067B (en) * 2019-07-16 2025-03-19 Federico Amezcua Amezcua A synergistic combination of s-ketorolaco and pregabalin in a pharmaceutical composition for the treatment of neuropathic pain
CN112353767A (en) * 2020-11-16 2021-02-12 海南锦瑞制药有限公司 Diltiazem hydrochloride and pregabalin composition, and preparation method and application thereof
CN116999560A (en) * 2022-04-30 2023-11-07 武汉思瓴生物科技有限公司 Drug combinations that can treat pain and their applications

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6129907A (en) 1999-08-04 2000-10-10 Colgate Palmolive Company Stable hydrogenated lupulone antibacterial oral compositions
AU2003207219A1 (en) 2002-02-05 2003-09-02 Ajinomoto Co., Inc. Medicinal compositions containing gabapentin or pregabalin and n-type calcium channel antagonist
DE10331305A1 (en) 2003-07-10 2005-02-17 Siemens Ag Communication system, peer-to-peer message filtering computer and method for processing a peer-to-peer message
AU2006248645A1 (en) 2005-05-20 2006-11-23 Pfizer Limited Synergistic combinations of non-steroidal antiinflammatory drugs with alpha-delta-ligands
EP2207569B1 (en) 2007-10-09 2013-03-27 Merck Patent GmbH Pharmaceutical compositions containing benfotiamine and one or more pharmaceutically active agents for the treatment of pain conditions of neuropathic origin
CN102908339A (en) 2007-11-23 2013-02-06 格吕伦塔尔有限公司 Tapentadol compositions
MX336979B (en) 2011-12-16 2016-02-09 Senosiain S A De C V Lab Antineuritic pharmaceutical combination and compositions.

Also Published As

Publication number Publication date
MX2014008336A (en) 2016-01-07
WO2016005897A1 (en) 2016-01-14
BR112017000359A2 (en) 2018-06-26
PE20171140A1 (en) 2017-08-09

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