Multiphase composite micromixer combined with flow dividing device
Technical Field
The utility model relates to the technical field of microfluidics, in particular to a multiphase composite micromixer combined with a flow dividing device.
Background
Standard solution configuration is of great importance in scientific and industrial production, and its functions include calibration of concentration instruments for determining other chemical substances, quality control, data comparison and calibration, etc. However, the existing standard solution preparation method has a plurality of problems, mechanical stirring is simple and easy to implement but long in time consumption, ultrasonic treatment is high in cost and can influence solution and solute, and stirring magnetons are not applicable to high-viscosity liquid.
In addition, it is a big problem to have all solutions reach the same concentration. The concept of an effective boundary layer exists during dissolution, there is a solid that can dissolve in a liquid, and if there is no flow of fluid, dissolution of the solid will occur by diffusion of the molecules. The diffusion process makes the fluid build concentration gradient inside, and as the diffusion time is prolonged, the concentration gradient becomes smaller and the dissolution speed becomes slower. If convection occurs in the fluid, dissolved material is continuously washed away by the fluid flowing over the surface, which is exacerbated as the movement of the fluid increases, and obviously the concentration gradient changes more steeply. Conventional treatment methods require dilution by calculation of the ratio and require time for them to reach the same concentration, which can take a lot of time in experimental investigation.
The microfluidic technology can well solve the problem. The micro-fluidic technology can realize micro-scale fluid control, and the automation degree in the process is high, and the high-flux characteristic can also greatly shorten the time required by reagent manufacturing.
The micromixer may be classified into a passive micromixer and an active micromixer according to the difference of input energy. The current micromixers have the following disadvantages:
1. The mixing effect is poor, namely, the fluid flow is mostly laminar under the microscale condition, and under the condition of smaller Reynolds number (10 or even below 1), the satisfactory mixing effect can not be achieved by simply relying on diffusion due to smaller inertia force of the fluid, and the research and design of the micromixer aiming at the condition of low Reynolds number are relatively insufficient at present.
2. Most mixers can only mix two liquids with uniform front and rear concentrations, cannot mix one liquid with nonuniform front and rear concentrations, and cannot be applied to a scene requiring taking a trace amount of quantitative concentration liquid.
3. The structure is complex, the processing difficulty is great, and in order to improve the mixing effect, the structural design of some micromixers is complex, for example, the micromixers have special geometric shapes, internal structures or micro-nano scale characteristics, which bring great challenges to manufacturing, high-precision processing equipment and process are needed, and the manufacturing cost and time are increased.
Disclosure of utility model
The utility model aims to provide a multiphase composite micromixer combined with a flow dividing device, which has the effects of high reliability, high mixing efficiency, wide application range and capability of carrying out multiphase and quantitative mixing, and can play a larger role in scientific research and social life.
The utility model provides a multiphase composite micromixer combining a flow dividing device, which comprises a mixing chip, a cover plate and an electromagnetic micro valve, wherein the mixing chip is provided with a mixing flow passage, the mixing flow passage comprises a liquid inlet, a flow dividing and manufacturing time difference area, a mixing area and a liquid outlet, the liquid inlet, the flow dividing and manufacturing time difference area, the mixing area and the liquid outlet are sequentially communicated, the flow dividing and manufacturing time difference area comprises a flow dividing narrow channel and a flow dividing wide channel, the inner diameter of the flow dividing narrow channel is smaller than that of the flow dividing wide channel, an input port of the flow dividing narrow channel is communicated with an input port of the flow dividing wide channel, an output port of the flow dividing narrow channel is communicated with an output port of the flow dividing wide channel, the cover plate is used for sealing and covering the mixing flow passage, and the electromagnetic micro valve is used for controlling the opening and closing of the liquid outlet.
In one embodiment, the split wide channel comprises a wide flow section and a narrow flow section which are communicated with each other, wherein the inner diameter of the wide flow section is larger than that of the narrow flow section, an input port of the wide flow section is communicated with an input port of the split narrow channel, and an output port of the narrow flow section is communicated with an output port of the split narrow channel.
In one embodiment, the wide flow section, the narrow flow section and the split narrow channel enclose a triangular shape.
In one embodiment, the mixing region is a T-shaped square wave type mixing channel.
In one embodiment, baffles are arranged at the corners of the T-shaped square wave type mixing channel.
In one embodiment, the cover plate is a glass cover plate.
In one embodiment, a valve groove is formed in the surface, facing away from the mixing flow channel, of the mixing chip, and the electromagnetic micro valve is arranged in the valve groove.
In one embodiment, the electromagnetic micro valve is provided with a spring, and the spring is used for pushing the electromagnetic micro valve which is not electrified to shade the liquid outlet.
The beneficial effects of the utility model are as follows:
1. the multiphase composite micromixer can rapidly mix liquid with uneven concentration before and after a single strip, and has high mixing efficiency and high mixing speed.
2. The speed of combining the electromagnetic micro valve is high, and the concentration mixing of the preset mass or volume of the solution is completed.
3. The multiphase composite micromixer skillfully utilizes the baffle structure, reduces the occupied space of the chip, has exquisite and simple structure, is convenient to manufacture and install, has modularized characteristics, and is easy to integrate and apply.
Drawings
In order to more clearly illustrate the technical solutions of the present utility model, the drawings that are needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present utility model, and that other drawings can be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram of a structure provided by an embodiment of the present utility model;
FIG. 2 is an enlarged schematic view of the portion A of FIG. 1;
FIG. 3 is a schematic view of the mixing channel structure of FIG. 1;
FIG. 4 is an enlarged schematic view of the portion B of FIG. 3;
FIG. 5 is a graph of the mixing effect of a T-shaped square wave mixing channel without baffles;
FIG. 6 is a graph of the mixing effect of a T-shaped square wave mixing channel after baffle plates are arranged;
FIG. 7 is a schematic diagram of a simulation provided by the present utility model;
FIG. 8 is a second simulation diagram provided by the present utility model;
FIG. 9 is a concentration surface plot;
Fig. 10 is a concentration plot of outlet fluid arc length in the interval 0-300 um.
The reference numerals are as follows:
10. 11, valve groove;
20. A cover plate;
30. An electromagnetic micro valve 31 and a spring;
40. Mixing flow channel, 41, liquid inlet, 42, flow dividing and manufacturing time difference area, 421, flow dividing narrow channel, 422, flow dividing wide channel, 4221, wide flow section, 4222, narrow flow section, 43, mixing area, 431, baffle, 44, liquid outlet.
Detailed Description
The technical solutions in the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model.
The utility model provides a multiphase compound micromixer combined with a flow dividing device, which is implemented as shown in fig. 1 to 4, and comprises a mixing chip 10, a cover plate 20 and an electromagnetic micro valve 30, wherein the mixing chip 10 is provided with a mixing flow channel 40, the mixing flow channel 40 comprises a liquid inlet 41, a flow dividing and manufacturing time difference area 42, a mixing area 43 and a liquid outlet 44 which are sequentially communicated, the flow dividing and manufacturing time difference area 42 comprises a flow dividing narrow channel 421 and a flow dividing wide channel 422, the inner diameter of the flow dividing narrow channel 421 is smaller than that of the flow dividing wide channel 422, an input port of the flow dividing narrow channel 421 is communicated with an input port of the flow dividing wide channel 422, an output port of the flow dividing narrow channel 421 is communicated with an output port of the flow dividing wide channel 422, the cover plate 20 is used for sealing and covering the mixing flow channel 40, particularly the cover plate 20 is a glass cover plate, and the electromagnetic micro valve 30 is used for controlling the opening and closing of the liquid outlet 44.
When the liquid mixing device is used, substances to be dissolved can be pre-buried in the liquid inlet 41, once fluid is input, the fluid can flow through the flow dividing and time difference manufacturing area 42, the liquid with the same concentration gradient can flow dividing and flow dividing narrow channel 421 and wide flow dividing channel 422, at the moment, the flow speed of the fluid in the wide flow dividing channel 422 can be reduced because the wide flow dividing channel 422 is suddenly widened from narrow, namely, when the fluid in the narrow flow dividing channel 421 and the fluid in the wide flow dividing channel 422 are recombined, the concentration of the fluid in the narrow flow dividing channel 421 is lower than that of the fluid in the wide flow dividing channel 422, and the purpose of front-back mixing of a section of uneven liquid is achieved.
After the fluids are joined, they are mixed in the mixing area 43, and after the mixing is completed, the electromagnetic micro valve 30 is only opened, and the mixed liquid can be output through the liquid outlet 44.
As shown in fig. 3, the split-flow wide channel 422 includes a wide flow section 4221 and a narrow flow section 4222 which are mutually connected, wherein the inner diameter of the wide flow section 4221 is larger than that of the narrow flow section 4222, the input port of the wide flow section 4221 is connected with the input port of the split-flow narrow channel 421, the output port of the narrow flow section 4222 is connected with the output port of the split-flow narrow channel 421, and the wide flow section 4221, the narrow flow section 4222 and the split-flow narrow channel 421 form a triangle.
After the arrangement mode is adopted, the arrangement area of the diversion wide channels 422 can be increased in a limited space, so that the dissolution effect in the diversion wide channels 422 is further improved.
As shown in fig. 1 to 3, in this embodiment, a valve groove 11 is disposed on the surface of the mixing chip 10 facing away from the mixing flow channel 40, an electromagnetic micro valve 30 is disposed in the valve groove 11, the electromagnetic micro valve 30 is provided with a spring 31, and the spring 31 is used for pushing the electromagnetic micro valve 30 that is not electrified to block the liquid outlet 44.
After the arrangement mode is adopted, when the electromagnetic micro valve 30 is not electrified, the electromagnetic micro valve 30 is subjected to thrust action due to the pretightening force action generated by the spring 31, so that the liquid outlet 44 is blocked, and when the electromagnetic micro valve 30 is electrified, the electromagnetic suction force generated by the electromagnetic micro valve 30 overcomes the elastic force of the spring 31, so that the electromagnetic micro valve 30 is in an open state, and fluid can smoothly flow out through the liquid outlet 44.
As shown in fig. 3 and 4, the mixing region 43 is a T-shaped square wave mixing channel, and the baffles 431 are disposed at the corners of the T-shaped square wave mixing channel.
After the arrangement, the baffle 431 can strengthen the vortex in the T-shaped square wave type mixing channel, so that the mixing effect is enhanced.
For example, fig. 5 is a mixing effect diagram of a T-shaped square wave type mixing channel when the baffle 431 is not provided, fig. 6 is a mixing effect diagram of a T-shaped square wave type mixing channel after the baffle 431 is provided, and the two are simulated by comsol 6.2.2, wherein the simulation setting parameters are that the inlet flow velocity v=0.03 m/s, the upper port concentration is 0mol/m 3, the lower port concentration is 1mol/m 3, and the comparison can show that the mixing efficiency of the T-shaped square wave type mixing channel after the baffle 431 is provided can be remarkably improved.
Specifically, the utility model also provides theoretical explanation and simulation verification, which are specifically as follows:
The fluid introduced into the liquid inlet 41 flows in the mixing flow channel 40 under the action of the air valve, and simultaneously dissolves the solute buried in the area of the liquid inlet 41 when flowing, because more solute is easy to form saturated liquid when the solute begins to dissolve, the solute in the area of the liquid inlet 41 is less and contacts with the fluid along with the time, so that the concentration of the fluid begins to be reduced, and the phenomenon that the concentration of the fluid entering the flow channel is higher than that at the rear end is formed. The fluid of the isoconcentration land is split into two after passing through the split and created moveout region 42 as described above. Because the fluid in the split wide channel 422 is to flow through the manufacturing time difference region, single-strength non-uniform fluid back and forth mixing is achieved when the split narrow channel 421 and the dissolution fluid in the split wide channel 422 meet. After that, the liquid enters a T-shaped square wave type mixing channel provided with a baffle 431, the corner enables the fluid to deflect vertically, the liquid in the T-shaped square wave type mixing channel is disturbed, obvious secondary flow is formed, and the mixing effect is enhanced. Because of the existence of the baffle 431, the speed of the fluid flowing through the gap between the baffle 431 and the pipe wall is increased, and meanwhile, a large centrifugal force is generated, the fluid flowing through the baffle 431 generates expansion vortex in the flow channel behind the baffle 431 under the action of the centrifugal force, the fluid is disturbed again, and the mixing effect is further enhanced.
The flow line of the fluid in the whole flow passage plane is predicted by comsol 6.2.2, and the speed of the fluid in the plane is calculated, so that the chip is manufactured to meet the requirement of micro quantitative sampling, and the concentration of the fluid in the linear length of an outlet is calculated within 0-300 um. The computational fluid dynamics software is based on finite elements, the simulation condition is that a circular area and a linear structure area are two-dimensional, fluid is water with sectional concentration, the concentration of 0-3s is 5mol/m 3, the concentration of 3-10s is (6.5-0.5 x t) mol/m 3, the geometric dimensions of the flow channels are all in the micrometer scale, wherein a numerical model adopts a continuous equation, a viscous incompressible Navier-Stokes equation and a convection diffusion equation.
The continuity equation is:
▽u=0
The viscous incompressible Navier-Stokes equation (Navier-Stokes Equations) is:
the convective diffusion equation is:
Wherein u is the velocity vector of the fluid, ρ is the fluid density, v is the kinematic viscosity of the fluid, t is the time, p is the fluid pressure, c is the molar concentration of the component, and D is the diffusion coefficient of the component.
Besides the basic hydrodynamic analysis equation, the Reynolds number (Re) can reflect the motion state of the fluid and is used for analyzing the mixed performance of the fluid, and for the design of the flow channel size, the estimation of the inflow speed and the comparison of the mixing efficiency have larger reference values, and the mathematical definition formula is as follows:
In the simulation process, the inner wall of the channel in the flow channel is set to be a boundary condition which can not slide, the outlet is not provided with pressure, and the temperature of the fluid is 298.15K.
From the simulation effect, the mixing effect is good, the error is small, the efficiency is high, and the structural device has sufficient feasibility, and is particularly shown in the following figures 7 to 10.
As shown in fig. 9, the density surface chart was observed, and it was found that the density chart color was almost uniform when the liquid was discharged from the liquid outlet 44.
As shown in FIG. 10, the concentration curve diagram of the outlet fluid arc length in the interval of 0-300um is observed, the extreme value is smaller than 0.04mol/m 3, the relative error is smaller than 1%, and the mixing effect and efficiency are higher.
While the foregoing is directed to the preferred embodiments of the present utility model, it will be appreciated by those skilled in the art that changes and modifications may be made without departing from the principles of the utility model, such changes and modifications are also intended to be within the scope of the utility model.