CN203929723U - Fluid capturing apparatus - Google Patents
Fluid capturing apparatus Download PDFInfo
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- CN203929723U CN203929723U CN201420198062.3U CN201420198062U CN203929723U CN 203929723 U CN203929723 U CN 203929723U CN 201420198062 U CN201420198062 U CN 201420198062U CN 203929723 U CN203929723 U CN 203929723U
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- mover
- groove
- stator
- face
- capturing apparatus
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- 239000012530 fluid Substances 0.000 title claims abstract description 33
- 238000012546 transfer Methods 0.000 claims description 4
- 238000003032 molecular docking Methods 0.000 claims description 2
- 238000004458 analytical method Methods 0.000 abstract description 25
- 230000003068 static effect Effects 0.000 abstract description 3
- 239000012898 sample dilution Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 description 34
- 238000010586 diagram Methods 0.000 description 10
- 238000010790 dilution Methods 0.000 description 10
- 239000012895 dilution Substances 0.000 description 10
- 238000005070 sampling Methods 0.000 description 10
- 238000002347 injection Methods 0.000 description 7
- 239000007924 injection Substances 0.000 description 7
- 239000007791 liquid phase Substances 0.000 description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 238000013461 design Methods 0.000 description 3
- 235000011187 glycerol Nutrition 0.000 description 2
- 238000004811 liquid chromatography Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000011144 upstream manufacturing Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000007405 data analysis Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000004817 gas chromatography Methods 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
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- Sampling And Sample Adjustment (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
A kind of fluid capturing apparatus that target fluid is carried out to trace picked-up.It is made up of stator and mover: mover is movable, and end face is carved with two or more grooves; Stator is static all the time, and end face correspondence position has two pairs or more interface, stator back side linking parsing pipeline.The crush seal assembling in opposite directions of the end face of stator and mover, on stator end face, the connection of interface is to realize by the groove of mover end face.After mover rotates to an angle, there is variation in the path on the end face coordinating with stator, originally be switched to current-carrying pipeline the inside at the groove b of target fluid passage, target fluid at groove b has also been switched to current-carrying system together, groove b volume is exactly the intake of target fluid, and groove b volume range is tens to receive and be raised to several microlitres.This has realized the object of micro-picked-up target fluid, and this has been avoided the Sample Dilution operation to be analyzed in stratographic analysis application, and then has reduced analysis deviation.
Description
Technical field
The utility model relates to a kind of fluid capturing apparatus, especially gas, liquid is carried out to micro-picked-up.
Background technology
Typical case's application of fluid analysis (gas-liquid) is gas chromatography, liquid chromatography, all needs to treat analytic sample and absorbs quantitatively.Current common practice is the quantitative picked-up (concrete principle is as Figure 1A-1, Figure 1A-2, Figure 1B-1, Figure 1B-2) of switching to implement sample by the A/B state of transfer valve.Transfer valve is made up of stator and mover: mover is rotatable, is carved with 3 grooves on end face; Stator is static all the time, on end face to there being 6 interfaces, back side linking parsing pipeline.The crush seal assembling in opposite directions of the end face of stator and mover, the connection on stator between any two adjacent interfaces is to realize by the groove of mover end face.A condition in Figure 1A-1 and Figure 1A-2 (Load loading), sample liquid to be analyzed flows through following path: the outside injection annulus 7-of the 5th interface 5-the first groove a-the 3rd interface 3-the 4th interface 4-the second groove b-the 6th interface 6-sewer pipe; Current-carrying liquid flows through following path: first interface 1-the 3rd groove c-the second interface 2-analytic system.The mover certain angle that turns clockwise, for the B state shown in Figure 1B-1 and Figure 1B-2 (Inject sample introduction), also rotation thereupon of groove on end face, the array mode of stator and mover has sent variation, and sample liquid to be analyzed flows through following path: the 5th interface 5-the second groove b-the 6th interface 6-sewer pipe; Current-carrying liquid flows through following path: the outside injection annulus 7-of first interface 1-the second groove a-the 3rd interface 3-the 4th interface 4-the 3rd groove c-the second interface 2-analytic system.A condition is switched to after B state, and " the outside injection annulus 7 of the first groove a-" inner sample liquid to be analyzed also automatically switches to current-carrying flow path system, completes the operation of quantitative picked-up sample to be analyzed.Picked-up volume is by " the outside injection annulus 7 of the first groove a-" internal duct volume decision, and minimum value is also greater than 5 microlitres conventionally.The common volume of the outside injection annulus 7 of chromatogram analysis equipment is 20 microlitres.The upper limit of detection of most of chromatograms is lower, therefore, need to treat analytic sample and first dilute decades of times, then enters analytic system by the sample to be analyzed switching after quantitative picked-up 20 microlitre dilutions.Dilution complex operation, more importantly brings very large analysis deviation, and manually the analysis deviation of dilution operation is even up to 10+%.
Utility model content
Operate and bring the problem of analysis deviation in order to overcome loaded down with trivial details dilution, the utility model provides a kind of switching by internal groove to realize the device of trace picked-up target fluid, therefore just can high concentration stoste direct injection analysis without dilution, and analyze the stability of data and repeated far above traditional dilution analysis method.
The fluid capturing apparatus that the utility model provides, there is the stator and the mover that switch for realizing two-way stream, realize wherein one of stream sample by the relative motion of described stator and mover and transfer to quantitatively an other road stream, wherein, the end face of mover has at least 2 grooves, the end face of stator has at least 2 docking ports, the crush seal assembling in opposite directions of the end face of stator and mover, and the each described groove on stator on the every pair of described interface and mover is for being directly communicated with and realizing one of described stream.
Described groove be 2 to more, be preferably 2～10
Described groove is best for being 4～6.
Preferably, described groove is evenly distributed, and the distance at the two ends of each described groove equates with the distance between interface every pair described.
The volume of part or all of described groove can be not identical.
The volume range of described groove can be 0.01 to receive and be raised to 5 microlitres.
The volume range of described groove is preferably 0.05 and receives and be raised to 2 microlitres.
The preferred movement mode of mover is for rotating.
The back side of described stator can be connected with the pipeline that is communicated with to form described two-way stream with described interface.Be the part that above-mentioned pipeline can be used as the utility model capturing apparatus, also can use time, reconnect.
Capturing apparatus of the present utility model in use, be arranged on the injector upstream of analytical equipment, the beneficial effects of the utility model are, do not affecting analytic function and the performance of existing device, do not change in client's use habit situation yet, avoided loaded down with trivial details dilution operation, can obtain simultaneously high-quality, analyze data reliably.
Brief description of the drawings
Figure 1A-1 is the fundamental diagram of the A condition of fluid capturing apparatus of the prior art;
Figure 1A-2 are the view of the mover under state shown in Figure 1A-1;
Figure 1B-1 is the fundamental diagram of the B state of fluid capturing apparatus of the prior art;
Figure 1B-2 are the view of the mover under state shown in Figure 1B-1;
Fig. 2 A-1 is the fundamental diagram of the A condition of the utility model fluid capturing apparatus;
Fig. 2 A-2 is the view of the mover under state shown in Fig. 2 A-1;
Fig. 2 B-1 is the fundamental diagram of the B state of the utility model fluid capturing apparatus;
Fig. 2 B-2 is the view of the mover under state shown in Fig. 2 B-1;
Fig. 3 A-1 is the fundamental diagram of the A condition of the utility model fluid capturing apparatus specific embodiment 1;
Fig. 3 A-2 is the view of the mover under state shown in Fig. 3 A-1;
Fig. 3 B-1 is the fundamental diagram of the B state of the utility model fluid capturing apparatus;
Fig. 3 B-2 is the view of the mover under state shown in Fig. 3 B-1;
Fig. 4 A-1 is the fundamental diagram of the A condition of the utility model fluid capturing apparatus specific embodiment 2;
Fig. 4 A-2 is the view of the mover under state shown in Fig. 4 A-1;
Fig. 4 B-1 is the fundamental diagram of the B state of the utility model fluid capturing apparatus;
Fig. 4 B-2 is the view of the mover under state shown in Fig. 4 B-1;
Fig. 5 A-1 is the fundamental diagram of the A condition of the utility model fluid capturing apparatus specific embodiment 3;
Fig. 5 A-2 is the view of the mover under state shown in Fig. 5 A-1;
Fig. 5 B-1 is the fundamental diagram of the B state of the utility model fluid capturing apparatus;
Fig. 5 B-2 is the view of the mover under state shown in Fig. 5 B-1;
Fig. 6 is the reproducible signal graph of liquid phase replicate analysis that utilizes fluid capturing apparatus of the present utility model to carry out;
Fig. 7 is the signal graph that utilizes the analysis results from residue tests that fluid capturing apparatus of the present utility model carries out.
Embodiment
The utility model solves the technical scheme that its technical matters adopts, and replaces traditional external injection annulus with the built-in groove on mover end face, realizes the trace picked-up for the treatment of analytic sample.Concrete principle is as shown in Fig. 2 A-1, Fig. 2 A-2, Fig. 2 B-1, Fig. 2 B-2: device is made up of stator and mover: mover is movable, typical motion mode is to rotate to an angle, end face is carved with 2 or 2 above grooves, and the length of groove equates with stator corresponding interface distance; Stator is static all the time, and end face correspondence position has 4 or 4 above interfaces, back side linking parsing pipeline.The crush seal assembling in opposite directions of the end face of stator and mover, the connection between 2 interfaces of stator is to realize by the groove of mover end face.A condition in Fig. 2 A-1 and Fig. 2 A-2 (Load loading), sample liquid to be analyzed flows through following path: the 3rd interface 3-the second groove b-the 4th interface 4-sewer pipe; Current-carrying liquid flows through following path: second interface 2-the first groove a-first interface 1-analytic system.Mover turns clockwise after certain angle, for B state shown in Fig. 2 B-1 and Fig. 2 B-2 (Inject sample introduction), also rotation thereupon of groove on mover end face, also there is variation in the array mode of stator and mover, and sample liquid to be analyzed flows through following path: the 3rd interface 3-the 3rd groove c-the 4th interface 4-sewer pipe; Current-carrying flows through following path: second interface 2-the first groove b-first interface 1-analytic system.A condition is switched to after B state, and " the second groove b " inner sample liquid to be analyzed also automatically switches to current-carrying system path, completes quantitative picked-up sample liquid operation to be analyzed, and intake is determined by " the second groove b " volume, conventionally receives and be raised to several microlitres from tens.Complete once after complete sampling action, mover rotates to an angle counterclockwise again, allows device recover A condition (Load loading), prepares sampling next time.
Below in conjunction with drawings and Examples, the utility model is further illustrated.
Embodiment 1
Concrete structure is shown in Fig. 3 A-1, Fig. 3 A-2, Fig. 3 B-1 and Fig. 3 B-2, on mover, only have 2 grooves, in the time of 3A-1 and Fig. 3 A-2A state (Load loading), sample liquid stream to be analyzed and current-carrying stream are communicated with by the second groove b and the first groove a of mover respectively.Mover turns clockwise certain angle while being switched to B state shown in Fig. 3 B-1 and Fig. 3 B-2 (Inject loading), and the 3rd interface 3 of sample flow path to be analyzed and the 4th interface 4 are not communicated with, and B state analysis sample liquid does not need to flow; Current-carrying stream is communicated with by the second groove b.In this design 1, the intake of sample liquid is determined by the volume of the second groove b.Complete once after complete sampling action, mover rotates to an angle counterclockwise again, allows device recover A condition (Load loading), and sample liquid stream the second groove b to be analyzed is communicated with, external force pump sample liquid flows through the second groove b, prepares sampling next time.
Embodiment 2
Concrete structure is shown in Fig. 4 A-1, Fig. 4 A-2, Fig. 4 B-1 and Fig. 4 B-2, has the groove of 6 different volumes on mover, the first groove a, and, the second groove b, the 3rd groove c, the 4th groove d, the 5th groove e and the 6th groove f.In the time of A condition shown in 4A-1 and Fig. 4 A-2 (Load loading), sample liquid stream to be analyzed and current-carrying stream are communicated with by the second groove b and the first groove a of mover respectively.Mover turns clockwise certain angle during to B state shown in Fig. 4 B-1 and Fig. 4 B-2 (Inject loading), and sample liquid flow route the 3rd groove c to be analyzed is communicated with; Current-carrying stream is communicated with by the second groove b, and the intake of sample liquid is determined by the volume of the second groove b.
After completing once and analyzing, sample liquid to be analyzed re-injects the 3rd interface 3 of stator, and now sample liquid flow route the 3rd groove c to be analyzed is communicated with, and then the mover certain angle that again turns clockwise completes blocked operation.The intake of current sample liquid equals the volume of the 3rd groove c.Use the 3rd groove c as quantitative sampling volume as thought always, complete once after complete sampling action, mover rotates to an angle counterclockwise again, allow device recover A condition (Load loading), sample liquid stream to be analyzed is communicated with by the 3rd groove c again, external force sample liquid flows through the 3rd groove c, prepares sampling next time.
This specific design has 6 different volumes grooves to select, and sample liquid to be analyzed flows through a certain groove, then rotates mover certain angle, allows this groove be communicated with the interface of current-carrying flow path system, has realized the object of quantitatively absorbing using this channel volume as sample.The utility model also can be designed to the related device of more grooves.Principle and using method are similar.
Embodiment 3
Concrete structure is shown in Fig. 5 A-1, Fig. 5 A-2, Fig. 5 B-1 and Fig. 5 B-2, has 3 grooves on mover.In the time of A condition shown in Fig. 5 A-1 and Fig. 5 A-2 (Load loading), sample liquid stream to be analyzed and current-carrying stream are communicated with by the second groove b and the first groove a of mover respectively.Mover moves a certain distance while being switched to B state shown in Fig. 5 B-1 and Fig. 5 B-2 (Inject loading) to the right, and sample flow path to be analyzed is communicated with by the 3rd groove c; Current-carrying stream is communicated with by the second groove b.In this design, the intake of sample liquid is determined by the volume of the second groove b.Complete once after complete sampling action, mover moves a certain distance recovery A condition more conversely to the left side, and sample liquid flow route the second groove b to be analyzed is communicated with, and external force pump drives sample liquid to flow through the second groove b, prepares sampling next time.
Below by the performance of experimental verification the utility model capturing apparatus.
Experiment adopts the high pressure liquid chromatography of Shimadzu: host C BM-20A, constant temperature oven CTO-20A, pump LC-20AT, detecting device RID-10A, and Bole (Bio-Rad) chromatographic column HPX-87H.Configuration glycerine sample liquid is detected object.Other are operating as liquid phase routine operation or according to shop instruction.The utility model apparatus structure adopting in experiment is shown in Fig. 2 A-1 and 2B-1, and the volume that plays the second groove b of sample liquid quantitative function on mover end face is 0.2 microlitre.The utility model device is connected on the upstream of existing high-pressure liquid phase system admission valve, and high-pressure liquid phase system mobile phase is according to current-carrying flow path in Fig. 2 B-1.Manually by sample liquid to be analyzed sampling injector rinse 3 times, then from the normal sample introduction of the utility model device.
Analyze the reappearance experiment of data
78g/L glycerine sample repeats 7 times and analyzes.Original signal is shown in Fig. 6.Data analysis shows to increase after this device at high-pressure liquid phase system, the mean deviation 0.0423% of same sample replicate analysis data, and coefficient of variation CV value is 0.058% (these two parameter values is all more low better).The full-automatic injector of the stability of replicate analysis data and liquid phase is suitable, reaches liquid chromatograph and think highly of the limit of complex analysis data reappearance.
Analysis interference between different samples
Whether have analysis residual phenomena in order to examine or check previous sample, two sample 78g/L to be analyzed and 5.1g/L compartment analyses that concentration difference is very large, repeat 2 times.Original signal is shown in Fig. 7.Data results shows: do not find the residual interference problem of analysis between sample adjacent, variable concentrations.
Reduce the requirement to operating personnel
Tradition dilution analysis method: in certain client unit, arbitrarily specify certain operating personnel according to classic method, one sample independently to be diluted 5 times, the then sample analysis after each dilution 1 time, totally 5 times, analyze maximum deviation-9.017%, mean deviation 3.61% and the coefficient of variation CV value 5.64% of data.Conventionally people is for the mean deviation of dilution analysis data is in 1～5% scope, and maximum deviation is in 3～15% scopes.The quality of analyzing data depends critically upon operating personnel's technical merit.
The utility model: under identical liquid phase systems, the utility model device is installed, by identical operating personnel to a sample (actual concentrations with suitable above), not diluting repetition sample introduction analyzes 5 times, analyze the maximum deviation 0.096% of data, mean deviation 0.044%, coefficient of variation CV value 0.062%.(these three values are all more low better).
| Number of times | Peak area | Mean value | Deviation (5) |
| 1 | 133907 | 133995.8 | -0.06627 |
| 2 | 133938 | 133995.8 | -0.04314 |
| 3 | 134008 | 133995.8 | 0.009105 |
| 4 | 134001 | 133995.8 | 0.003881 |
| 5 | 134125 | 133995.8 | 0.096421 |
| Mean value | 133995.8 | Mean deviation | 0.043763 |
Learn by contrast experiment: use after the utility model, greatly reduce operating personnel's artificial analysis deviation, the reappearance that repeats sample introduction analysis data is very good, suitable with the full-automatic injector of liquid chromatography.Do not observe the analysis quality of data and operating personnel's technical merit and have the obvious degree of association.
Claims (9)
1. fluid capturing apparatus, there is stator and mover for realizing two-way stream, realize wherein one of stream sample by the relative motion of described stator and mover and transfer to quantitatively an other road stream, it is characterized in that, the end face of mover has at least 2 grooves, the end face of stator has at least 2 docking ports, the crush seal assembling in opposite directions of the end face of stator and mover, and the each described groove on stator on the every pair of described interface and mover is for being directly communicated with and realizing one of described stream.
2. fluid capturing apparatus according to claim 1, is characterized in that, described groove is 2～10.
3. fluid capturing apparatus according to claim 2, is characterized in that, described groove is 4～6.
4. fluid capturing apparatus according to claim 1, is characterized in that, described groove is evenly distributed, and the distance at the two ends of each described groove equates with the distance between interface every pair described.
5. fluid capturing apparatus according to claim 1, is characterized in that, the volume of part or all of described groove is not identical.
6. fluid capturing apparatus according to claim 5, is characterized in that, the volume range of described groove is 0.01 to receive and be raised to 5 microlitres.
7. fluid capturing apparatus according to claim 6, is characterized in that, the volume range of described groove is 0.05 to receive and be raised to 2 microlitres.
8. fluid capturing apparatus according to claim 1, is characterized in that, the mode of motion of mover is for rotating.
9. fluid capturing apparatus according to claim 1, is characterized in that, the back side of described stator is connected with the pipeline that is communicated with to form described two-way stream with described interface.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420198062.3U CN203929723U (en) | 2014-04-22 | 2014-04-22 | Fluid capturing apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420198062.3U CN203929723U (en) | 2014-04-22 | 2014-04-22 | Fluid capturing apparatus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203929723U true CN203929723U (en) | 2014-11-05 |
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ID=51825522
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420198062.3U Expired - Fee Related CN203929723U (en) | 2014-04-22 | 2014-04-22 | Fluid capturing apparatus |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203929723U (en) |
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2014
- 2014-04-22 CN CN201420198062.3U patent/CN203929723U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20141105 Termination date: 20150422 |
|
| EXPY | Termination of patent right or utility model |