CN203885672U - 冠状动脉急诊治疗用双联药物洗脱支架 - Google Patents
冠状动脉急诊治疗用双联药物洗脱支架 Download PDFInfo
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- CN203885672U CN203885672U CN201420322764.8U CN201420322764U CN203885672U CN 203885672 U CN203885672 U CN 203885672U CN 201420322764 U CN201420322764 U CN 201420322764U CN 203885672 U CN203885672 U CN 203885672U
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- 210000004351 coronary vessel Anatomy 0.000 title claims abstract description 13
- 239000003814 drug Substances 0.000 title claims abstract description 13
- 229940079593 drug Drugs 0.000 title abstract 4
- 239000011248 coating agent Substances 0.000 claims abstract description 16
- 238000000576 coating method Methods 0.000 claims abstract description 16
- 108010073863 saruplase Proteins 0.000 claims abstract description 8
- 230000002537 thrombolytic effect Effects 0.000 claims abstract description 8
- ZAHRKKWIAAJSAO-UHFFFAOYSA-N rapamycin Natural products COCC(O)C(=C/C(C)C(=O)CC(OC(=O)C1CCCCN1C(=O)C(=O)C2(O)OC(CC(OC)C(=CC=CC=CC(C)CC(C)C(=O)C)C)CCC2C)C(C)CC3CCC(O)C(C3)OC)C ZAHRKKWIAAJSAO-UHFFFAOYSA-N 0.000 claims abstract description 6
- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 claims abstract description 6
- 229960002930 sirolimus Drugs 0.000 claims abstract description 6
- 239000003146 anticoagulant agent Substances 0.000 claims description 6
- 206010020880 Hypertrophy Diseases 0.000 claims description 5
- 210000004204 blood vessel Anatomy 0.000 claims description 4
- 208000007536 Thrombosis Diseases 0.000 abstract description 8
- 239000000463 material Substances 0.000 abstract description 2
- 238000002560 therapeutic procedure Methods 0.000 abstract description 2
- 206010020718 hyperplasia Diseases 0.000 abstract 2
- 230000008719 thickening Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- KKJUPNGICOCCDW-UHFFFAOYSA-N 7-N,N-Dimethylamino-1,2,3,4,5-pentathiocyclooctane Chemical compound CN(C)C1CSSSSSC1 KKJUPNGICOCCDW-UHFFFAOYSA-N 0.000 description 1
- 208000006117 ST-elevation myocardial infarction Diseases 0.000 description 1
- 206010072810 Vascular wall hypertrophy Diseases 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 208000037803 restenosis Diseases 0.000 description 1
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Abstract
本实用新型涉及一种医疗器械，具体是一种冠状动脉急诊治疗用双联药物洗脱支架，包括由若干支架杆支撑形成的支架，所述支架杆一侧靠近血管腔侧上涂覆有由尿激酶原制成的溶栓涂层，支架杆另一侧靠近血管壁侧上涂覆有由雷帕霉素制成的防增生涂层。本实用新型所述的冠状动脉急诊治疗用双联药物洗脱支架，结构新颖、构思巧妙，雷帕霉素制成的防增生涂层在有效抑制血管壁内膜增厚的同时，溶栓涂层的尿激酶原释放出来有效地减少急诊经冠状动脉介入治疗后支架血栓形成的并发症，研究材料证明支架置入后的血栓形成主要集中在第一周之内，而溶栓涂层的尿激酶原释放时间为3至5天，与血栓形成时间吻合。
Description
技术领域
本实用新型涉及一种医疗器械，具体是一种冠状动脉急诊治疗用双联药物洗脱支架。
背景技术
药物洗脱支架有效地解决了冠状动脉支架置入后再狭窄的问题。在急性ST段抬高性心肌梗死，介入治疗是获益最大的疾病。但是在高血栓负荷状态下置入支架后，无复流、慢血流以及支架内血栓的形成严重影响了疗效。
发明内容
本实用新型为了解决上述技术问题，提供了一种冠状动脉急诊治疗用双联药物洗脱支架。
本实用新型是通过以下技术方案实现：冠状动脉急诊治疗用双联药物洗脱支架，包括由若干支架杆支撑形成的支架，所述支架杆一侧靠近血管腔侧上涂覆有由尿激酶原制成的溶栓涂层，支架杆另一侧靠近血管壁侧上涂覆有由雷帕霉素制成的防增生涂层。
本实用新型所述的冠状动脉急诊治疗用双联药物洗脱支架，结构新颖、构思巧妙，雷帕霉素制成的防增生涂层在有效抑制血管壁内膜增厚的同时，溶栓涂层的尿激酶原释放出来有效地减少急诊经冠状动脉介入治疗后支架血栓形成的并发症，研究材料证明支架置入后的血栓形成主要集中在第一周之内，而溶栓涂层的尿激酶原释放时间为3至5天，与血栓形成时间吻合。
附图说明
图1为本实用新型所述冠状动脉急诊治疗用双联药物洗脱支架的支架杆的剖面图。
图中：1-支架杆，2-溶栓涂层，3-防增生涂层。
具体实施方式
冠状动脉急诊治疗用双联药物洗脱支架，包括由若干支架杆1支撑形成的支架，所述支架杆1一侧靠近血管腔侧上涂覆有由尿激酶原制成的溶栓涂层2，支架杆1另一侧靠近血管壁侧上涂覆有由雷帕霉素制成的防增生涂层3。
Claims (1)
1.冠状动脉急诊治疗用双联药物洗脱支架，包括由若干支架杆（1）支撑形成的支架，其特征在于，所述支架杆（1）一侧靠近血管腔侧上涂覆有由尿激酶原制成的溶栓涂层（2），支架杆（1）另一侧靠近血管壁侧上涂覆有由雷帕霉素制成的防增生涂层（3）。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420322764.8U CN203885672U (zh) | 2014-06-18 | 2014-06-18 | 冠状动脉急诊治疗用双联药物洗脱支架 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420322764.8U CN203885672U (zh) | 2014-06-18 | 2014-06-18 | 冠状动脉急诊治疗用双联药物洗脱支架 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203885672U true CN203885672U (zh) | 2014-10-22 |
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| CN201420322764.8U Expired - Fee Related CN203885672U (zh) | 2014-06-18 | 2014-06-18 | 冠状动脉急诊治疗用双联药物洗脱支架 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203885672U (zh) |
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2014
- 2014-06-18 CN CN201420322764.8U patent/CN203885672U/zh not_active Expired - Fee Related
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| C14 | Grant of patent or utility model | ||
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| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20141022 Termination date: 20170618 |