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CN203634235U - Left atrial appendage occluder - Google Patents

Left atrial appendage occluder Download PDF

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Publication number
CN203634235U
CN203634235U CN201320725116.2U CN201320725116U CN203634235U CN 203634235 U CN203634235 U CN 203634235U CN 201320725116 U CN201320725116 U CN 201320725116U CN 203634235 U CN203634235 U CN 203634235U
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China
Prior art keywords
atrial appendage
left atrial
film body
appendage occluder
thin
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Expired - Fee Related
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CN201320725116.2U
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Chinese (zh)
Inventor
李安宁
林逸贤
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Lifetech Scientific Shenzhen Co Ltd
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Lifetech Scientific Shenzhen Co Ltd
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Priority to CN201320725116.2U priority Critical patent/CN203634235U/en
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Abstract

The utility model relates to an left atrial appendage occluder which comprises a sealing disc and a fixed bracket connected with the sealing disc and positioned on one side of the sealing disc, wherein the fixed bracket includes a connecting part connected to the sealing disc, and a plurality of support bodies; after radially radiating from the connecting part to the remote end and being matched with one another to form concave parts, the support bodies are bent to extend to the close end to form a plurality of mutually-separated suspended supporting sections which are each provided with at least one anchoring thorn facing the sealing disc; the left atrial appendage occluder further comprises a film body; the support bodies are connected in series through the film body. The left atrial appendage occluder can effectively restrain relative positions of the support sections and relative motion among the support sections through the film body, and thus avoids the twisting of the support sections when the fixed bracket is pushed out and released from a delivery sheath.

Description

Left atrial appendage occlusion device
Technical field
This utility model relates to medical apparatus and instruments, relates in particular to a kind of method getting involved by microcatheter technology utilization and be sent to the stopper at the selected position of human body, produces the disease of thrombosis so that apoplexy for prevention because atrial fibrillation causes left auricle.
Background technology
It is to utilize at present increasing Therapeutic Method that the method getting involved by microcatheter technology utilization is treated disease, and Catheter Interventional Therapy method is placed various materials, apparatus and medicine heart, the artery and vein vascular to human body.
Placing stopper by conduit interventional method in the heart of human body, arteriovenous, left auricle time, due to heart, the artery and vein vascular of human body, especially the anatomical structure complexity of left auricle, require apparatus accurately to arrive predetermined position, anatomical structure, the mechanics that will well adapt to predetermined position require and hemodynamics requirement simultaneously, must have a well design to the structure of apparatus.Only human body is being produced under the prerequisite of Wicresoft's wound, first, in the skin place puncture near blood vessel, seal wire is from puncture orifice intravasation, conduit is under the guiding of seal wire, its one end arrives predetermined position, and the other end is stayed external, then utilizes conduit and pusher that apparatus is sent to predetermined position.In the time carrying out this type of operation, require very little flexible conduit, conduit and seal wire will be designed under X-ray, there is good development simultaneously.Once conduit has arrived predetermined position, removes seal wire, utilize passage that pusher sets up by conduit the end of apparatus guiding catheter, in the time that apparatus all exposes from the end of conduit, apparatus will disconnect with pusher, to realize the release of apparatus.
Such as, place stopper in left auricle by conduit interventional method, prevention forms thrombosis because atrial fibrillation causes left auricle, and this thrombosis goes upward to the apoplexy that brain causes; Or prevent this XUESHUANTONG to cross human body blood circulation arrival other positions of health, the systemic thromboembolism causing.Put stopper in left auricle, shutoff left auricle, blocking-up enters the blood flow of left auricle, can eliminate because atrial fibrillation causes the thrombosed risk of left auricle, prevention of stroke.Such apparatus is to be all connected with carrier by screw thread conventionally at present, reaches and is easy to connect the effect that pushes and discharge.
With reference to figure 1 and Fig. 2, Fig. 1 is the position view of existing a kind of left atrial appendage occlusion device in heart and left auricle anatomical structure, and Fig. 2 is the structural representation of existing a kind of left atrial appendage occlusion device.Wherein: 01 is that left atrium, 02 is that left auricle, 03 is left auricle chamber wall.This stopper comprises two parts, seal disc 11 and fixed mount 12, fixed mount 12 is made up of multiple supporters 13, on each supporter 13, be provided with mooring anchor (or being called anchor thorn) 15, each supporter 13 starts to extend to the bulb of supporter end 14 from mooring anchor 15 positions, all relatively separate; The seal disc 11 of this left atrial appendage occlusion device is provided with attaching nut 16.This stopper has good elasticity, can be incorporated in the wide sheath of 2~4mm, by vascular access, be sent in left auricle 02, then withdraw from leisure sheath pipe, the fixed mount 12 of stopper can launch at left auricle intracavity, the shape that the supporter 13 of fixed mount 12 can adapt to left auricle 02 abuts on left heart wall, and the mooring anchor 15 on supporter 13 can thrust in left auricle chamber wall 03 simultaneously, ensures firm fixing, and seal disc 11 can paste the oral area at left auricle 02, as shown in Figure 1.Finally free the wirerope being connected with left atrial appendage occlusion device, reach like this shutoff left auricle, blocking blood flow enters the object of left auricle.
There is following limitation in aforementioned left atrial appendage occlusion device: the supporter end of fixed mount is relatively to separate, and unsettled, due to the feature of its structure, takeing in sheath Guan Zhonghou, again release sheath pipe, the risk that exists supporter end to tangle, can cause fixed mount normally to launch failure, make operative failure.
Utility model content
The purpose of this utility model is to provide a kind of left atrial appendage occlusion device, avoids tangling between supporter.
The technical solution adopted in the utility model is: the left atrial appendage occlusion device providing comprises seal disc and is connected and is positioned at the fixed mount of described seal disc one side with described seal disc; Described fixed mount comprises the connecting portion and the multiple supporter that are connected with described seal disc; Described multiple supporter gives off from described connecting portion to distal radial and coordinates and forms depressed area, form multiple unsettled supporting sections spaced apart from each other through bending to proximal extension, and described supporting section is provided with at least one thorn of the anchor towards described seal disc, described left atrial appendage occlusion device also comprises thin-film body, and all supporters are all connected by thin-film body.
In the left atrial appendage occlusion device according to this utility model embodiment, described thin-film body comprises at least one annular membrane, and described annular membrane is fixed on all supporters, around described depressed area, and exposes all or part of described depressed area.
In the left atrial appendage occlusion device according to this utility model embodiment, described thin-film body comprises spheric thin film, and described spheric thin film also hides described depressed area.
In the left atrial appendage occlusion device according to this utility model embodiment, described at least one, anchor stings through described thin-film body.
In the left atrial appendage occlusion device according to this utility model embodiment, the thickness that described thin-film body is positioned at described anchor thorn near zone is more than or equal to the thickness in all the other regions of described thin-film body.
In the left atrial appendage occlusion device according to this utility model embodiment, described supporter is also provided with multiple fixing holes, and described thin-film body is fixed on described supporter in the mode of sewing up by described multiple fixing holes.
In the left atrial appendage occlusion device according to this utility model embodiment, described thin-film body overlays on described supporter by bio-compatible adhesive plaster.
In the left atrial appendage occlusion device according to this utility model embodiment, the root 1~5mm of the described anchor thorn of proximal edge distance of described thin-film body.
In the left atrial appendage occlusion device according to this utility model embodiment, described anchor thorn is through stretching out length outside described thin-film body after described thin-film body between 1~3mm.
Compared with prior art, the technical scheme that this utility model adopts at least possesses following advantage: because left atrial appendage occlusion device also comprises the thin-film body of all supporters of connecting, can effectively retrain relative position and the relative motion between each supporting section by this thin-film body, thereby reduce tangling between supporting section while even avoiding left atrial appendage occlusion device fixed mount to release release from delivery sheath.
Brief description of the drawings
Below in conjunction with drawings and Examples, the utility model is described in further detail, in accompanying drawing:
Fig. 1 is the position view of existing left atrial appendage occlusion device in heart and left auricle anatomical structure;
Fig. 2 is the structural representation of existing left atrial appendage occlusion device;
Fig. 3 shows the schematic diagram of the left atrial appendage occlusion device that this utility model one embodiment provides;
Fig. 4 is the schematic diagram at another visual angle of left atrial appendage occlusion device shown in Fig. 3;
Fig. 5 and 6 shows the schematic diagram of fixed mount in Fig. 3;
Fig. 7 shows the partial schematic diagram of supporter and thin-film body in Fig. 3;
Fig. 8 shows the schematic diagram after the device of left atrial appendage occlusion shown in Fig. 3 discharges in left auricle;
The schematic diagram of the left atrial appendage occlusion device that Fig. 9 provides for the another embodiment of this utility model;
Figure 10 is the schematic diagram at another visual angle of left atrial appendage occlusion device shown in Fig. 9;
Figure 11 is the schematic diagram after left atrial appendage occlusion device shown in Fig. 9 discharges in left auricle;
Figure 12 is the schematic diagram of left atrial appendage occlusion device shown in Fig. 9 do not seal left auricle oral area completely in dispose procedure time.
Detailed description of the invention
In order to make the purpose of this utility model, technical scheme and advantage clearer, below in conjunction with drawings and Examples, this utility model is further elaborated.Should be appreciated that specific embodiment described herein is only in order to explain this utility model, and be not used in restriction this utility model.
In order more clearly to describe the structure of left atrial appendage occlusion device (being designated hereinafter simply as stopper), limit term " far-end " and " near-end " herein, above-mentioned term is the common terminology in interventional medical device field.Particularly, " far-end " represents one end away from operator in operation process, and " near-end " represents one end near operator in operation process.
Referring to Fig. 3 to Fig. 8, the left atrial appendage occlusion device 10 that this utility model one embodiment provides comprises seal disc 100, is connected and is positioned at the fixed mount 200 of seal disc 100 1 sides and is fixed on the thin-film body 300 on fixed mount 200 with seal disc 100.
Seal disc 100 is formed by the macromolecule silk braiding of nickel-titanium metal silk or bio-compatible, and its relative fixed mount 200 is positioned at near-end.
Fixed mount 200 comprises the connecting portion 210 and the multiple supporter 220 that are connected with seal disc 100; Multiple supporters 220 give off from connecting portion 210 to distal radial and coordinate and form depressed area 221, form multiple unsettled supporting sections 222 spaced apart from each other through bending to proximal extension, and supporting section 222 is provided with at least one thorn of the anchor towards seal disc 100 223.
In actual production, can, from the end of a NiTi pipe along cutting out many supporters 220 towards the direction of the other end, then strut each supporter 220 with mould, heat treatment shaping, the part that this NiTi pipe is not cut is connecting portion 210.Can require to select according to mechanical property and dimensions the number of supporter 220, as the six roots of sensation, eight, nine, 12 and ten six roots of sensation etc.When cutting, the anchor thorn 223 arranging on supporter 220 is cut out simultaneously.
Referring to Fig. 5 and Fig. 6, supporter 220 comprises multiple sections of drawing that give off to distal radial from connecting portion 210 224, multiple son field 225 and multiple unsettled supporting section 222.Respectively the section of drawing 224, centered by connecting portion 210, complements each other to form depressed area 221.Each section of drawing 224 is connected with two son fields 225 respectively away from one end of connecting portion 210.Described two son field 225 shapes form an angle.Preferably, form acute angle.One near self in every son field 225 two son fields corresponding with the adjacent section of drawing 224 crosses, and forms unsettled supporting section 222 through bending backward proximal extension.Each supporting section 222 is spaced from each other.That is to say, around connecting portion 210, the every section of drawing 224 coordinates formation to be similar to " people " character form structure with two coupled son fields 225, and every adjacent two " people " font structure extends a supporting section 222 after the one end away from connecting portion 210 is connected.Supporting section 222 roughly becomes U-shaped section, and the one end being connected with son field 225 is provided with anchor thorn 223, the treated formation spheroid 226 in its unsettled end.Referring to Fig. 6, the section of drawing 224 and son field 225 are equipped with multiple fixing holes 227 near the end of supporting section 222.
Still as shown in Figures 3 and 4, thin-film body 300 adopts PET or PTFE or silica gel material to make conventionally, also can adopt other biocompatibility and physical property to meet the requirements of thin-film material.This thin-film body 300 comprises an annular membrane, and it stings 223 by anchor and is fixed on whole son fields 225 of fixed mount 200 with the mode of sewing up cooperation, connects thus, and expose all or part of depressed area 221 with all supporters 220.When this stopper 10 is after left auricle discharges, thin-film body 300 forms the outer surface that supporter 220 contacts with left auricle chamber wall.Described stitching refers to passes fixing hole 227 suture, then through annular membrane body 300, then suture knotting fixes thin-film body 300.
As shown in Figure 7, the width of annular membrane body 300 can sting 223 according to anchor and determines to the position of the supporters 220 of fixed mount 200 and the fixing hole 227 of annular membrane body 300.In the present embodiment, this thin-film body 300 can sting 223 roots towards proximal extension 1~5mm from anchor, and thin-film body 300 can be from the fixing hole 227 of supporter 220 and annular membrane body 300 towards approximately 2~10mm of remote extension.The thickness of this thin-film body 300 should meet the following conditions: anchor thorn 223 should be between 1~3mm through stretching out length outside thin-film body 300 after thin-film body 300, does not come off guaranteeing after anchor thorn 223 inserts left auricle.
Schematic diagram after the stopper that Fig. 8 shows above-described embodiment discharges in left auricle, as shown in Figure 8, after fixed mount 200 is placed in left auricle, fixed mount 200 and annular membrane body 300 launch with the state of Fig. 8, the supporter 220 of this fixed mount 200 is fitted in left auricle chamber wall 03 together with annular membrane body 300, fixed mount 200 and left auricle chamber wall 03 are with a Cylindrical Surfaces Contact, comparing in the existing left atrial appendage occlusion device shown in Fig. 1 only has each supporter 220 to contact with left auricle chamber wall 03, contact area increases tens times, left auricle chamber wall 03 is stressed more even like this, anchor thorn 223 on each supporter 220 is penetrated in left auricle chamber wall 03 uniformly, simultaneously stressed less in unit are, avoid the stressed excessive damage causing left auricle chamber wall 03 of certain point.
And thin-film body 300 can retrain the relative distance between each supporter 220 effectively, avoids relative motion.Thin-film body 300 has softly thin, compressible and elastic feature, therefore in the process of releasing again after fixed mount 200 is taken in delivery sheath, this thin-film body 300 pastes all the time on the supporter 220 of fixed mount 200, and along with supporter 220 closes up and launches, even avoid thereby can reduce the risk that tangles between supporter 220, the carrying out smoothly of the operation of guarantee.
Separately, due to structure and the size characteristics of annular membrane body 300, the root that its edge exceeds anchor thorn 223 has a segment distance, therefore in the time that anchor thorn 223 stabs left auricle chamber wall 03 and penetrates into certain degree of depth, annular membrane body 300 entirety can be to certain obstruction control action of having thrust of anchor thorn 223, can arrive the effect that effective control anchor thorn 223 thrusts left auricle chamber wall 03 degree of depth, reduce the excessive damage of coming to left auricle chamber cornice due to unbalance stress.In addition, under extreme situation, certain anchor thorn 223 has punctured left auricle chamber wall 03, according to existing left atrial appendage occlusion device, the blood of left atrial appendage can penetrate in pericardial cavity from the position puncturing, and can cause pericardial effusion, serious meeting causes cardiac arrest, critical life.But for this embodiment, once left auricle chamber wall 03 is punctured by anchor thorn 223, this thin-film body 300 can cover piercing orientation immediately, facilitate the formation of microthrombus simultaneously nearby, stop up punctured hole by thrombosis, stop blood to penetrate in pericardial cavity, lower the even risk of cardiac arrest of pericardial effusion.Meanwhile, thin-film body can accelerate the thrombosis of the blood of left interior portion, and then flesh, accelerates the process of whole left auricle flesh.
Referring to Fig. 9 to Figure 12, the left atrial appendage occlusion device 20 that the another embodiment of this utility model provides has the structure similar with aforementioned left atrial appendage occlusion device 10, comprise seal disc 400, be connected and be positioned at the fixed mount 500 of seal disc 400 1 sides with seal disc 400, and be fixed on the thin-film body 600 on fixed mount 500, itself and left atrial appendage occlusion device 10 differences are, this thin-film body 600 is spheric, proximal edge is apart from the root 1~5mm of anchor thorn 523, the remote area of thin-film body 600 covers whole depressed area (capped, not show in figure).Thin-film body 600 is fixed by suture way at fixing hole 527 and 528 places with supporter 520, and each supporter 520 is provided with same fixing hole 527 and 528 in same position.Fixing mode is identical with above-mentioned first embodiment.
The thin-film body 600 of this another embodiment except have with above-mentioned first embodiment same mechanism of action and advantage, also there is following characteristics, under some extreme situations, as shown in figure 12, the seal disc 11 of left atrial appendage occlusion device does not seal the oral area of left auricle completely, the direction that blood may represent along arrow 05 enters left auricle, at this moment the spherical thin-film body 600 in this second embodiment can form second barrier near oral area in auricle, stop blood to enter the position, more deep of left auricle, reduce thrombotic risk.
Compared with previous embodiment, the left atrial appendage occlusion device of the present embodiment can not blocked because left atrial appendage occlusion device seal disc seals left auricle oral area completely and cause the blood flow that enters left auricle deep, reduces thrombotic risk.
It is worth mentioning that, in other embodiment of this utility model, thin-film body also can arrange different thickness by zones of different, for example, the thin-film body that is positioned at anchor thorn near zone is more than or equal to the thickness in these all the other regions of thin-film body, thus, once left auricle chamber wall is punctured by anchor, the anchor thorn that will more effectively prevent the thickening thin-film body that is positioned at anchor thorn near zone injects hemorrhage after left auricle, accelerates thrombosis.This thin-film body also can be laminate film structure, comprises compared with plural layers in anchor thorn region.For example, thin-film body can comprise ground floor thin film and second layer thin film, and ground floor thin film is hemispherical thin film, and second layer thin film is annular membrane, and ground floor thin film and second layer thin film are overlapping at anchor thorn near zone, to strengthen the thickness of anchor thorn near zone thin-film body.This thin-film body also can comprise multiple thin film, and these multiple thin film are intervally arranged successively along distal-to-proximal direction on fixed mount.
Thin-film body can be fixed on the arbitrarily applicable position of supporter, comprises any place or the many places of depressed area, the section of drawing, son field and supporting section, as long as guarantee to be connected in series under naturalness at this left atrial appendage occlusion device and fixing each supporter.Separately, no matter whether anchor thorn, through thin-film body, all also can be fixed to thin-film body on supporter by alternate manner.For example, utilize biological glue that thin-film body is bonded on fixed mount.If thin-film body is made up of pellosil, can utilize the characteristic of silica gel itself, the silica gel materials of liquid is adhered on supporter through Overheating Treatment.
The foregoing is only preferred embodiment of the present utility model; not in order to limit this utility model; all any amendments of doing within spirit of the present utility model and principle, be equal to and replace and improvement etc., within all should being included in protection domain of the present utility model.

Claims (9)

1.一种左心耳封堵器,包括密封盘、以及与所述密封盘连接且位于所述密封盘一侧的固定架;所述固定架包括与所述密封盘连接的连接部、以及多个支撑体;所述多个支撑体从所述连接部向远端径向辐射出并配合形成凹陷区后,经弯折向近端延伸形成多个相互隔开的悬空支承段,且所述支承段设有至少一个朝向所述密封盘的锚刺,其特征在于:所述左心耳封堵器还包括薄膜体,所有所述支撑体通过所述薄膜体串联。1. A left atrial appendage occluder, comprising a sealing disc and a fixing frame that is connected with the sealing disc and is positioned at one side of the sealing disc; the fixing bracket includes a connecting portion that is connected with the sealing disc, and multiple a support body; the plurality of support bodies radially radiate from the connecting part to the distal end and cooperate to form a concave area, and then extend to the proximal end after being bent to form a plurality of suspended support sections spaced apart from each other, and the said support bodies The support section is provided with at least one anchor thorn facing the sealing disk, and the feature is that: the left atrial appendage occluder further includes a thin film body, and all the supporting bodies are connected in series through the thin film body. 2.如权利要求1所述的左心耳封堵器,其特征在于:所述薄膜体包括至少一个环绕所述凹陷区的环形薄膜,所述环形薄膜与所有支撑体串联,且暴露出全部或部分所述凹陷区。2. The left atrial appendage occluder according to claim 1, wherein the film body comprises at least one annular film surrounding the recessed area, the annular film is connected in series with all supports, and exposes all or part of the recessed area. 3.如权利要求1所述的左心耳封堵器,其特征在于:所述薄膜体包括球面形薄膜,所述球面形薄膜还遮盖所述凹陷区。3 . The left atrial appendage occluder according to claim 1 , wherein the film body comprises a spherical film, and the spherical film also covers the depressed area. 4 . 4.如权利要求1-3任一项所述的左心耳封堵器,其特征在于:至少一个所述锚刺穿过所述薄膜体。4. The left atrial appendage occluder according to any one of claims 1-3, characterized in that at least one of said anchors pierces through said membrane body. 5.如权利要求4所述的左心耳封堵器,其特征在于:所述薄膜体位于所述锚刺附近区域的厚度大于或等于所述薄膜体其余区域的厚度。5 . The left atrial appendage occluder according to claim 4 , wherein the thickness of the film body near the anchor bar is greater than or equal to the thickness of the rest of the film body. 6 . 6.如权利要求4所述的左心耳封堵器,其特征在于:所述支撑体还设有多个固定孔,所述薄膜体通过所述多个固定孔以缝合的方式固定在所述支撑体上。6. The left atrial appendage occluder as claimed in claim 4, characterized in that: said supporting body is also provided with a plurality of fixing holes, and said thin film body is fixed on said fixing hole by suturing. on the support. 7.如权利要求4所述的左心耳封堵器,其特征在于:所述薄膜体通过生物相容粘胶贴覆在所述支撑体上。7. The left atrial appendage occluder according to claim 4, characterized in that: the film body is pasted on the support body by biocompatible adhesive. 8.如权利要求4所述的左心耳封堵器,其特征在于:所述薄膜体的近端边缘距离所述锚刺的根部1~5mm。8. The left atrial appendage occluder according to claim 4, characterized in that: the proximal edge of the membrane body is 1-5 mm away from the root of the anchor thorn. 9.如权利要求4所述的左心耳封堵器,其特征在于:所述锚刺穿过所述薄膜体后伸出所述薄膜体之外的长度介于1~3mm。9 . The left atrial appendage occluder according to claim 4 , wherein the length of the anchor penetrating through the membrane body and protruding out of the membrane body is 1-3 mm. 10 .
CN201320725116.2U 2013-11-14 2013-11-14 Left atrial appendage occluder Expired - Fee Related CN203634235U (en)

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Cited By (10)

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Publication number Priority date Publication date Assignee Title
CN103598902A (en) * 2013-11-14 2014-02-26 先健科技(深圳)有限公司 Left aurcle plugging device
CN104274224A (en) * 2014-09-29 2015-01-14 上海形状记忆合金材料有限公司 Left atrial appendage occlusion device
WO2017016411A1 (en) * 2015-07-28 2017-02-02 杭州诺茂医疗科技有限公司 Left auricle occluding device
WO2017071353A1 (en) * 2015-10-28 2017-05-04 先健科技(深圳)有限公司 Left atrial appendage occluder
CN106901792A (en) * 2015-12-29 2017-06-30 深圳市科奕顿生物医疗科技有限公司 Occluder for left auricle
WO2017114348A1 (en) * 2015-12-29 2017-07-06 深圳市科奕顿生物医疗科技有限公司 Left atrial appendage closure device
CN110025349A (en) * 2019-05-08 2019-07-19 广东脉搏医疗科技有限公司 Anchoring type occluder for left auricle
EP3398536A4 (en) * 2015-12-31 2019-08-21 Lifetech Scientific (Shenzhen) Co., Ltd. LEFT APPARATUS OCCLUSION DEVICE LEFT
EP3398537A4 (en) * 2015-12-31 2019-09-04 Lifetech Scientific (Shenzhen) Co., Ltd. OCCLUSION DEVICE OF THE LEFT APPENDIX LEFT
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WO2015070733A1 (en) * 2013-11-14 2015-05-21 先健科技(深圳)有限公司 Left atrial appendage occluder
CN103598902B (en) * 2013-11-14 2017-01-25 先健科技(深圳)有限公司 Left aurcle plugging device
US11806019B2 (en) 2013-11-14 2023-11-07 Lifetech Scientific (Shenzhen) Co., Ltd Left atrial appendage occluder
CN103598902A (en) * 2013-11-14 2014-02-26 先健科技(深圳)有限公司 Left aurcle plugging device
CN104274224A (en) * 2014-09-29 2015-01-14 上海形状记忆合金材料有限公司 Left atrial appendage occlusion device
EP3241498B1 (en) 2014-12-31 2019-09-18 Lifetech Scientific (Shenzhen) Co., Ltd. Left atrial appendage occluder
CN114287986B (en) * 2014-12-31 2023-12-01 先健科技(深圳)有限公司 left atrial appendage occluder
CN114287986A (en) * 2014-12-31 2022-04-08 先健科技(深圳)有限公司 Left auricle plugging device
WO2017016411A1 (en) * 2015-07-28 2017-02-02 杭州诺茂医疗科技有限公司 Left auricle occluding device
US11026694B2 (en) 2015-07-28 2021-06-08 Hangzhou Nuomao Medtech Co., Ltd. Left atrial appendage occluder
WO2017071353A1 (en) * 2015-10-28 2017-05-04 先健科技(深圳)有限公司 Left atrial appendage occluder
US10813646B2 (en) 2015-10-28 2020-10-27 Lifetech Scientific (Shenzhen) Co., Ltd Left atrial appendage occluder
RU2738426C1 (en) * 2015-12-29 2020-12-14 Шэньчжэнь Кид Биомедикал Текнолоджи Ко.Лтд Left atrial appendage occluder (versions)
CN106901792B (en) * 2015-12-29 2019-11-01 深圳市科奕顿生物医疗科技有限公司 Occluder for left auricle
AU2016381148B2 (en) * 2015-12-29 2021-12-09 Shenzhen Kyd Biomedical Technology Co.Ltd Left atrial appendage closure device
US11291454B2 (en) 2015-12-29 2022-04-05 Shenzhen Kyd Biomedical Technology Co. Ltd. Left atrial appendage closure apparatus
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